Patent application number | Description | Published |
20090005764 | Method for Modifying the Refractive Index of Ocular Tissues - A method for modifying the refractive index of ocular tissues. The method comprises irradiating select regions of ocular tissue with a visible or near-IR laser. The irradiation results in the formation of structures in the ocular tissue, characterized by a change in refractive index, and which exhibit little or no scattering loss. | 01-01-2009 |
20090076187 | High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers - An intraocular lens comprising a polymer that is prepared from a monomer mixture comprising a monomer of formula | 03-19-2009 |
20090141234 | High Water Content Silicone Hydrogels - Silicone hydrogels formed from a hydrated polymerization product of a monomer mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; and (b) a minor amount of a silicone-containing monomer, wherein the hydrogel has a water content of greater than 50 weight percent are disclosed. | 06-04-2009 |
20090146328 | Method for Providing Lens Blanks - A method provides a machineable silicon-containing lens blank by removal of diluent from the lens blank. The method involves casting a lens blank in a mold, wherein the lens blank is made of a polymerization product of a monomeric mixture comprising a silicone-containing monomer and an organic diluent; removing the lens blank from the mold; and removing organic diluent from the lens blank. | 06-11-2009 |
20090168012 | COATING SOLUTIONS COMPRISING SEGMENTED INTERACTIVE BLOCK COPOLYMERS - This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reacting with complementary surface functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method. | 07-02-2009 |
20090168013 | Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains - A method for reducing the modulus of polymer siloxane hydrogel compositions by employing monomeric polysiloxanes endcapped with trimethylsilyl to reduce the crosslinking density of the hydrogel. The synthesis consists of a single vessel acid catalyzed ring opening polymerization and may be employed to produce copolymers useful as hydrogel contact lens materials. | 07-02-2009 |
20090169716 | COATING SOLUTIONS COMPRISING SURFACE ACTIVE SEGMENTED BLOCK COPOLYMERS - This invention is directed toward surface treatment of a device. The surface treatment comprises the placing of surface active segmented block copolymers to the surface of the substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method. | 07-02-2009 |
20090171027 | SEGMENTED INTERACTIVE BLOCK COPOLYMERS - This invention is directed toward interactive segmented block copolymers useful to treat the surface of a substrate by means of interactive functionalities of the interactive segmented block copolymer material binding with complementary surface functionalities of the polymer substrate. | 07-02-2009 |
20090171049 | SEGMENTED REACTIVE BLOCK COPOLYMERS - This invention is directed toward reactive segmented block copolymers useful to treat the surface of a substrate by means of reactive functionalities of the reactive segmented block copolymer material reacting with complementary surface reactive functionalities of the polymer substrate. | 07-02-2009 |
20090171050 | SURFACE ACTIVE SEGMENTED BLOCK COPOLYMERS - This invention is directed toward surface active segmented block copolymers useful to treat the surface of a substrate by means of surface active functionalities of the surface active segmented block copolymer material binding with complementary surface functionalities of the polymer substrate. | 07-02-2009 |
20090171459 | COATING SOLUTIONS COMPRISING SEGMENTED REACTIVE BLOCK COPOLYMERS - This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method. | 07-02-2009 |
20090173044 | Packaging Solutions - Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a substantially water-soluble silicone-containing surfactant. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity. | 07-09-2009 |
20090191256 | HIGH WATER CONTENT OPHTHALMIC DEVICES - An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed. | 07-30-2009 |
20090192275 | MULTI-ARMED MACROMONOMERS - Multi-armed macromonomers containing multiple side chains attached to a siloxy-containing core terminated on each end with one or more first substantially linear polysiloxane radicals having a polymerizable ethylenically unsaturated-containing terminal group, wherein each side chain comprises a second substantially linear polysiloxane radical having a polymerizable ethylenically unsaturated-containing terminal group are disclosed. Biomedical devices such as contact lenses formed from the multi-armed macromonomers are also disclosed. | 07-30-2009 |
20090274744 | Drug delivery system based on cationic siloxanyl macromonomers - Matrix controlled diffusion drug delivery systems are described herein which are based on one or more silicon-containing monomers of the general formula: | 11-05-2009 |
20090274745 | Drug delivery systems based on catonic siloxanyl macromonomers - Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: | 11-05-2009 |
20100039613 | SILICONE CONTACT LENSES WITH WRINKLED SURFACE - At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens. | 02-18-2010 |
20100118261 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES - Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics. | 05-13-2010 |
20100298933 | Optical Material and Method for Modifying the Refractive Index - The invention is directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. | 11-25-2010 |
20100315588 | Biomedical devices - Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a hydrophilic polymer comprising one or more hydrophilic units and one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed. | 12-16-2010 |
20100317816 | Biomedical devices - Biomedical devices such as contact lenses formed from a comprising a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization of one or more ethylenically unsaturated hydrophilic monomers or one or more ethylenically unsaturated hydrophobic monomers are disclosed. | 12-16-2010 |
20100318185 | Biomedical Devices - Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed. | 12-16-2010 |
20110009519 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 01-13-2011 |
20110009587 | MONO ETHYLENICALLY UNSATURATED POLYCARBOSILOXANE MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 01-13-2011 |
20110009658 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 01-13-2011 |
20110115110 | Method of Making Silicone Hydrogels with Fluorinated Side Chain Polysiloxanes - A method of making a silicone hydrogel contact lens from a monomer mixture that includes: N-vinyl-N-methyl acetamide, N-vinyl pyrrolidone or a mixture thereof; a monofunctional polysiloxanylalkyl monomer, and a polysiloxane-containing monomer having a perfluorinated side chain on a terminal carbon. The monomer mixture is charged to a mold and then subjected to spin casting or static casting. The casted mold is exposed to visible light or UV radiation. The resulting silicone hydrogel contact lens has an oxygen permeability of at least about 120 Barrers, a water content of at least about 20 weight percent, and a modulus from 40 g/mm | 05-19-2011 |
20110146206 | SYNTHESIS OF CATIONIC SILOXANE PREPOLYMERS - This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing the cationic siloxane prepolymer. | 06-23-2011 |
20120141408 | High Water Content Ophthalmic Devices - An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed. | 06-07-2012 |
20120277342 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES - Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics. | 11-01-2012 |
20120329905 | High Refractive Index Lenses - An optical copolymer comprising: a constituent derived from a sulfated lens monomer of general formula I | 12-27-2012 |
20130138093 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX - An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer. | 05-30-2013 |
20130178934 | Optical Material and Method for Modifying the Refractive Index - A laser system for modifying the index of refraction of an optical hydrogel material. The laser system comprises a computer program to determine the position and shape of refractive structures to be written into the optical hydrogel material to correct a patient's vision, and a focused laser that generates laser light having a wavelength of from 400 nm to 900 nm, and which operates with an average power of 10 mW to 1000 mW to produce a pulse energy from 0.05 nJ to 1000 nJ with a peak intensity at focus of greater than 10 | 07-11-2013 |
20130197125 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 08-01-2013 |
20130226162 | Method for Modifying the Refractive Index of Ocular Tissues - A laser system for changing the index of refraction of cornea tissue in a living eye. The laser system comprises a laser that provides laser pulses with a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ, and a control device for setting the operating parameters of the laser below an optical breakdown threshold of the tissue to avoid photo-disruption and tissue destruction of the tissue, and to direct the laser pulses at the cornea tissue resulting in a change in the index of refraction of the tissue within regions irradiated by the laser pulses. | 08-29-2013 |
20130289294 | ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUPS COMPRISING POLYCARBOSILOXANE MONOMERS - The present application relates to novel monomers comprising polycarbosiloxane monomers useful in certain specific embodiments in the manufacture of devices. More particularly, the present application relates to certain ethylenically unsaturated free radical polymerizable monomers comprising polycarbosiloxane monomers. Even more particularly, the present application pertains to monomers comprising polycarbosiloxane monomers which further comprise at least two ethylenically unsaturated free radical polymerizable groups. | 10-31-2013 |
20140371481 | SYNTHESIS OF FREE RADICAL POLYMERIZABLE ETHYLENICALLY UNSATURATED POLOXAMERS AND POLOXAMINES - A new synthetic method of forming free radical polymerizable end terminal functionalized poloxamers and poloxamines in commercial scale batches which uses a binary system of inhibitors to eliminate the formation of high molecular weight impurities. It has also been surprisingly discovered that the inorganic impurities formed during the commercial scale synthetic process are removed by the use of resin materials. | 12-18-2014 |