Patent application number | Description | Published |
20080265208 | Functional infrared flourescent particle - An infrared fluorescent particle comprising a functional group or a substance that is capable of binding to an analyte, wherein fluorescence at infrared wavelength is emitted from the particle upon exposure of the particle to excitation light at infrared wavelength. The infrared fluorescent particle of the present invention is capable of binding to the analyte. Due to a high penetration of the fluorescence and the excitation light into biological substances, the infrared fluorescent particle of the present invention can reduce an influence of luminescence, light absorption or light scattering which is occurred due to the analyte and the surrounding substances. | 10-30-2008 |
20090029482 | FUNCTIONAL PARTICLE, AND METHOD FOR SEPARATION OF TARGET SUBSTANCE USING THE SAME - The particles of the present invention are high density particles which enable a preferential binding of a target substance thereto and inhibit a binding of “substances other than the target substance” thereto. The particles of the present invention are characterized in that a substance or functional group capable of binding to a target substance is immobilized on the surface of a particle body; the particles have a density of 3.5 g/cm | 01-29-2009 |
20110048162 | Grip - A grip comprises a grip body forming a gripping control portion of a manually operable device to be held with the operator's palm and fingers. The grip body includes a ball-receiving surface coming into contact with the ball of the thumb, a palm-receiving surface coming into contact with a middle portion of the palm and the ball of the little finger, a finger-receiving surface coming into contact with the fingers, an open surface positioned between the tips of the fingers and the ball of the thumb for receiving the thumb when the grip body is held, and a switch mounted on a top portion of the grip body to be operable with the thumb. The grip body further comprises a thumb-guiding portion in the form of a shallow groove formed at an upper part of the ball-receiving surface of the grip body, the inside of the first joint of the thumb being placed along the thumb-guiding portion when the switch is operated, and a rising portion formed on at least either one of portions between the thumb-guiding surface and the open surface and between the thumb-guiding surface and the palm-receiving surface for applying resistance when the operator's hand advances into the switch. | 03-03-2011 |
20110089118 | SURFACE-ROUGHENED HIGH-DENSITY FUNCTIONAL PARTICLE, METHOD FOR PRODUCING THE SAME AND METHOD FOR TREATING TARGET SUBSTANCE WITH THE SAME - The particle of the present invention is a high-density particle to which a target substance can be bound, wherein the surface of the particle body is a roughened surface. The particle is characterized in that a substance or functional group to which a target substance can bind is immobilized on the roughened surface of the particle body, and the specific surface area of the particle is 1.4 to 100 times the specific surface area of a true spherical particle having the same particle size and the same density as those of the particle of the invention. In the particle of the invention, the accumulated micropore volume [cm | 04-21-2011 |
20120061608 | FUNCTIONAL PARTICLE WITH ROUGH-SURFACED POLYMER COATING - There is provided a magnetic particle to which a large amount of target substance can bind upon separation, analysis and the like of the target substance, the particle exhibiting a higher rate of the magnetic separation. The magnetic particle to which a target substance can bind, comprising a core particle having magnetism and a polymer coat layer comprising a polymer shell portion in which a rough coating of polymer is provided on a surface of the core particle. This magnetic particle has a roughness due to a surface roughness of the polymer shell portion wherein a specific surface area (m | 03-15-2012 |
Patent application number | Description | Published |
20080320609 | Diabetes Model Animal - We prepared a transgene comprising human HB-EGF precursor cDNA, as a diphtheria toxin receptor gene, at the downstream of an insulin promoter, and introduced this transgene into a mouse fertilized egg, to produce a transgenic mouse of the present invention. In this mouse, human HB-EGF precursors are expressed specifically in islet beta cells, and by injection of diphtheria toxin, islet beta cells are selectively destroyed, resulting in that the mouse shows diabetes two or three days after the injection. This mouse can be utilized in screening and development of new medicines and therapy protocols for diabetes. | 12-25-2008 |
20090217394 | Diabetes Model Animal - The present invention relates to a diabetes animal model. Specifically, the present invention relates to a transgenic nonhuman animal, into which recombinant DNA comprising a gene encoding a diphtheria toxin receptor and an insulin promoter for regulating expression of the above gene has been introduced. | 08-27-2009 |
20100235926 | Hairless Transgenic Animal - The present invention provides a hairless transgenic nonhuman animal used in the development of a therapy for dermatitis such as human atopic dermatitis and drug discovery. Specifically, the present invention provides a transgenic nonhuman animal, into which recombinant DNA comprising a heparin-binding EGF gene and a type 2 keratin gene promoter for regulating expression of the above gene has been introduced. | 09-16-2010 |