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Alicia

Alicia Aispuro, Coachella, CA US

Patent application numberDescriptionPublished
20140013988SHORT DURATION CHEMILUMINESCENT COMPOSITION - One aspect of the invention relates to chemiluminescent compositions comprising an oxalate composition, an activator composition and a H01-16-2014
20140013989SHORT DURATION CHEMILUMINESCENT COMPOSITION - One aspect of the invention relates to chemiluminescent compositions comprising an oxalate composition, an activator composition and a H01-16-2014

Alicia Algeciras-Schimnich, Rochester, MN US

Patent application numberDescriptionPublished
20120164626DETECTION OF HIGH GRADE DYSPLASIA IN CERVICAL CELLS - Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.06-28-2012
20130237590ASSESSING THYROID NEOPLASMS - This document provides methods and materials involved in assessing thyroid neoplasms. For example, methods and materials for using microRNA (miR) levels (e.g., miR122 levels) to determine whether a thyroid neoplasm (e.g., a follicular thyroid neoplasm) is benign or malignant as well as methods and materials for using miR levels (e.g., miR122 levels) to determine whether a malignant thyroid cancer patient is likely to have a favorable or unfavorable outcome are provided. This document also provides methods and materials involved in treating cancer.09-12-2013

Alicia Algeciras-Schimnich, Naperville, IL US

Patent application numberDescriptionPublished
20090269768DETECTION OF HIGH GRADE DYSPLASIA IN CERVICAL CELLS - Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.10-29-2009

Alicia Allamena, Manheim, PA US

Patent application numberDescriptionPublished
20090100768COVER FOR PRESTRESSED CONCRETE MEMBER - A cover includes a body adapted to secure over a fitting disposed in a prestressed concrete member for lifting the concrete member. The body has a surface feature configured to achieve a substantially fluid tight seal with the concrete member.04-23-2009
20090293389COVER FOR PRESTRESSED CONCRETE MEMBER - A prestressed structural concrete system is disclosed that includes a prestressed concrete structural member and a cover configured to securely engage a cavity of the member to substantially seal the cavity from an outside environment. The cover includes a surface configured to achieve a substantially fluid tight seal with the concrete member.12-03-2009

Alicia Bertone, Columbus, OH US

Patent application numberDescriptionPublished
20080233564Methods of Using Databases to Greate Gene-Expression Microarrays, Microarrays Greated Thereby, and Uses of the Microarrays - Methods of preparing biological databases, and databases prepared according to those methods. In some embodiments, the methods can be performed entirely using computer resources, relying solely on publicly available biological sequence information. The methods of the invention can be used to generate species-specific nucleic acid microarrays 09-25-2008

Alicia Boto Castro, San Cristobal ES

Patent application numberDescriptionPublished
20120157520DIOXANES DERIVED FROM REGROUPING CARBOHYDRATES AND C-GLYCOSIDES, PROCESS FOR OBTAINING SAME AND USES THEREOF - The present invention relates to compounds with a dioxane nucleus derived from carbohydrates and C-glucosides, process for obtaining same, to the use of such compounds as cytotoxic and antiproliferative agents and to the use thereof for producing a cancer treatment drug.06-21-2012

Alicia Bravo Garcia, Madrid ES

Patent application numberDescriptionPublished
20100120675INHIBITOR OF THE URACIL-DNA GLYCOSYLASE ENZYME AND USES THEREOF - The present invention relates to a protein which has the capacity to bind to and inhibit the viral uracil DNA glycosylase (UDG) enzyme and its use as a therapeutic agent; in particular, as an antiviral agent.05-13-2010
20120040890INHIBITOR OF THE URACIL-DNA GLYCOSYLASE ENZYME AND USES THEREOF - The present invention relates to a protein which has the capacity to bind to and inhibit the viral uracil DNA glycosylase (UDG) enzyme and its use as a therapeutic agent; in particular, as an antiviral agent.02-16-2012

Alicia Brown, Fayetteville, AR US

Alicia Casals Gelpi, Barcelona ES

Patent application numberDescriptionPublished
20120136372Robotic System for Laparoscopic Surgery - It comprises a supporting structure in which at least one arm is slidably attached. Each arm comprises first and second members hinged to each other. The first member is rotatably hinged to the supporting structure and it can be rotated about a longitudinal axis and the second member may receive a joint having at least two degrees of freedom for attaching a tool. The longitudinal axis of the first member is substantially perpendicular to an axis joining the first member and the second member to each other. A simplified architecture is obtained allowing for accurate and efficient spatial movement of the tool holding arm.05-31-2012

Alicia Casals Gelpí, Sant Just Desvern ES

Patent application numberDescriptionPublished
20130182417LAMP - A lamp having a first module for being attached to a ceiling or wall element, a second module connected to the first module and being rotatable with respect to the first module along a first axis, a third module having one or more light-emitting elements, the third module being connected to the second module and rotatable with respect to the second module along a second axis, the second axis being substantially perpendicular to the first axis.07-18-2013
20150184839LAMP AND PLENUM FOR LAMINAR AIR FLOW CEILING - A lamp having a first module for being attached to a ceiling or wall element, a second module connected to the first module and being rotatable with respect to the first module along a first axis, a third module having one or more light-emitting elements, the third module being connected to the second module and rotatable with respect to the second module along a second axis, the second axis being substantially perpendicular to the first axis.07-02-2015

Alicia Casals Gelpí, Sant Just Desvern ES

Patent application numberDescriptionPublished
20130182417LAMP - A lamp having a first module for being attached to a ceiling or wall element, a second module connected to the first module and being rotatable with respect to the first module along a first axis, a third module having one or more light-emitting elements, the third module being connected to the second module and rotatable with respect to the second module along a second axis, the second axis being substantially perpendicular to the first axis.07-18-2013

Alicia Chung, Berkeley, CA US

Patent application numberDescriptionPublished
20150376272INHIBITION OF ANGIOGENESIS IN REFRACTORY TUMORS - The present invention relates generally to the inhibition of tumor angiogenesis. In particular, the invention concerns the prevention or treatment of tumor angiogenesis and the suppression of tumor growth in tumors refractory to an anti-vascular endothelial growth factor (VEGF) treatment, using IL-17 antagonists, such as anti-IL-17 antibodies and other antagonists.12-31-2015

Alicia Cirujeda Ranzenberger, Zaragoza ES

Patent application numberDescriptionPublished
20160000022BIODEGRADABLE MULCH FOR AGRICULTURAL APPLICATIONS - Biodegradable mulch of the type used in various agricultural applications is made by multi-layer extrusion from a mixture of two compostable biodegradable polymers that comply with the EN13432 standard and that include potato starch, a black masterbatch and biodegradable recycled polymers. The mulch self-degrades in a short period of time, becoming a compostable material that enriches the soil, avoiding the collecting and cleaning tasks that are necessary in conventional mulches.01-07-2016

Alicia Constain, Miami, FL US

Patent application numberDescriptionPublished
20150105710UPPER BODY POSTURE CORRECTOR ASSEMBLY - The present invention pertains to a posture correcting assembly comprising a first strap with a first loop, a first band and a first attachment point; and a second strap with a second loop, a second band and a second attachment point, wherein the first loop hangs from a first shoulder of the user's body, the second loop hangs from a second shoulder of the users body, the first band wraps posteriorly around the user's body, the second band wraps posteriorly around the user's body, and the first attachment point and the second attachment point interconnect at the anterior side of the user's body. The present invention also pertains to a method for placing the fore mentioned posture correcting assembly on a user's body.04-16-2015

Alicia Da Conceicao, San Jose, CA US

Patent application numberDescriptionPublished
20140089612ELECTRONIC COUNTER IN NON-VOLATILE LIMITED ENDURANCE MEMORY - An electronic counter comprising 03-27-2014

Alicia Dobarro Rodríguez, Rubí-Barcelona ES

Patent application numberDescriptionPublished
20150037406NOVEL CRYSTALLINE FORM OF SITAGLIPTIN SULFATE - A novel crystalline form of sitagliptin sulfate is provided. In addition, a method for obtaining the crystalline form, pharmaceutical compositions comprising the novel crystalline form and the crystalline form for use as a medicament are provided.02-05-2015

Alicia El Haj, Highpeak GB

Patent application numberDescriptionPublished
20110034753STEM CELL TARGETING AND ACTIVATION USING MAGNETIC PARTICLES - The present invention provides a method of selectively activating and/or targeting stem cells which enables the cells to then be manipulated mechanically in a remote manner wherein the method comprises magnetically manipulating a stem cell in vivo or in vitro by the association of a magnetisable particle within the stem cell.02-10-2011

Alicia Espeleta Vega, Monterrey MX

Patent application numberDescriptionPublished
20090011109Method For Producing a Casing-Less Sausage or Similar Type Food Product and Product Thus Obtained - A process for elaborating a casing-less sausage- or similar-type food product, the process comprises the steps consisting in preparing an emulsion-type sausage paste having a gel-like viscosity; extruding the sausage paste into portions of a predetermined shape, which maintain said shape and which have at least one essentially flat surface; cooking the upper and lower surfaces of the said portions in order to form a skin that is obtained by applying heat to the external sausage paste of said portions, thereby leaving a core which is surrounded by the skin and which consists of the sausage paste that was not used to form the skin; performing a second cooking step in order to cook the cores, thereby forming sausage-type food products; and finally cooling the sausage-type food products prior to packing. The product thus obtained consists of a body which has at least one essentially-flat surface and which has a skin that is obtained upon heating, and a core which is surrounded by the skin and which consists of the cooked sausage paste that was not used to form the skin.01-08-2009
20100074998Meat Substitute Food Product And Process For Preparing The Same - A process for preparing meat substitute food products, including the steps of hydrating under vacuum of at least one vegetable protein mixed with water and at least one colorant; mixing at least one meat product with the hydrated and colored vegetable protein mixture; mixing flavoring units and texturised units into the mixture of meat products and hydrated and colored vegetable protein, thus obtaining a prepared paste; cooking said prepared paste; and shaping said cooked paste to produce an appearance similar to a meat product. The substitute meat food product obtained according to the invention can have the appearance, for example, of example, to steak, cutlet, skirt steak, cured steak, breaded veal cutlet, breaded skirt steak, veal escalope, a shredded meat, ground meat, lump meat, meat strips or meatballs.03-25-2010

Patent applications by Alicia Espeleta Vega, Monterrey MX

Alicia Essler, North Yorkshire GB

Patent application numberDescriptionPublished
20090104690DEVICE FOR DETECTING AN ENZYME IN A SAMPLE - A device for detecting a mammalian host-derived enzyme in a sample of a wound fluid, said device comprising: a housing having an inlet for the sample and side walls defining a fluid flow path extending from said inlet an indicator moiety that is bound to a solid substrate by means of a peptide linker moiety that is cleavable by said host-derived enzyme, said solid substrate being located in a reaction zone of said fluid flow path; and a detector moiety located in a detection zone downstream from the reaction zone in said fluid flow path, wherein the detector moiety interacts with an indicator moiety that has been cleaved from said solid substrate to produce a detectable change in said detection zone. Suitably, the device further comprises a control moiety located in a control zone in said device, wherein the control moiety can interact with a component of the wound fluid sample to improve the accuracy of the device. Also provided are systems comprising a device of the invention and a swab or biopsy punch adapted for use therewith.04-23-2009

Alicia Foucourt, Canteleu FR

Patent application numberDescriptionPublished
20140275064DYRK1 INHIBITORS AND USES THEREOF - The present invention relates to novel thiazolo[5,4-f]quinazoline compounds and methods that are useful in the amelioration, treatment or control of Down's syndrome or early Alzheimer's disease or in the amelioration, treatment or control of cancers, especially solid tumors. More specifically, the invention relates to DYRK1A and/or DYRK1B inhibitors and to methods for preparing such compounds.09-18-2014

Alicia GarcÍa Arroyo, Madrid ES

Patent application numberDescriptionPublished
20160129128ANTIBODY DRUG CONJUGATES - Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R05-12-2016

Alicia Gomez-Lopez, Madrid ES

Patent application numberDescriptionPublished
20120107809METHOD FOR SIMULTANEOUSLY DETECTING HISTOPLASMA CAPSULATUM AND PARACOCCIDIOIDES BRASILIENSIS - The present invention relates to a method for simultaneously detecting DNA of 05-03-2012

Alicia Gurnee, Watsonville, CA US

Patent application numberDescriptionPublished
20150262515Cord Clamp Identifiers - An identification bead includes a first element having a size and shape with engagement elements and a first trough from one edge to another, a second element having the same size and shape with engagement elements, a second trough from one edge to another, a surface for addition of indicia, and rubber-like insert elements with half-cylindrical troughs matching the troughs of the rigid elements, and a thickness. The first and second rigid elements are enabled to join with the engagement elements engaged and the insert elements between the rigid elements with the half-cylindrical first and second troughs facing in a manner to provide a cylindrical channel for a wire or cable, such that the joining of the rigid elements deforms the insert elements, placing pressure on a wire or cable passing through the cylindrical channel.09-17-2015

Alicia Hammond, Gulf Shores, AL US

Patent application numberDescriptionPublished
20150375920TRASH BAG DISPENSING SYSTEMS AND METHODS - A system for dispensing trash bags comprises a dispenser including an opening from which stored trash bags may be removed. A prong is positioned to extend partially across the opening of the dispenser. In an additional embodiment, the dispenser is stored within a container having a plurality of exterior walls, an upper opening, and a floor. The floor of the dispenser contains an elevated portion with an aperture extending therethrough. A prong is positioned to extend partially across the aperture. In additional embodiments, the disclosure pertains to methods of removing a trash bag from a dispenser where the bag comes into contact with a prong extending either from the dispenser or the container. The prong acts to at least partially unfold the bag upon removal from the dispenser, aiding the user in securing the trash bag to a garbage can.12-31-2015

Alicia Hegglin, Zug CH

Patent application numberDescriptionPublished
20140170737STACKABLE MICRO-FLUIDIC CELLS - An assay assembly that includes an assay bar having a plurality flow cells is disclosed. Each of the flow cells includes an inlet, an outlet, and an inside surface defining an inner volume. The outlet includes a valve that is configured to retain liquid within the inner volume of the flow cell. Each assay bar is configured to be reversibly stacked upon another assay bar, such that the flow cells of the stacked assay bars are in fluid communication with each other. This way, the outlet of a first flow cell of a first assay bar is in fluid communication with the inlet of a second flow cell of a second assay bar. The assay assembly may include a multitude of assay bars to form a composite assay assembly, with the flow cells of the stacked assay bars being in fluid communication with each other.06-19-2014

Alicia Higa-Brauneck, Hawthorne, CA US

Patent application numberDescriptionPublished
20140159751Passive Multi-Layered Corrosion Sensor - The invention concerns corrosion sensors comprising a resistor, a voltage meter for determining voltage output across said resistor; and at least three different layers, each layer comprising a different material, said layers comprising: (a) non-corrosive conducting layer; (b) metal layer; and (c) electrically insulating layer deposed between the conducting layer and the metal layer; wherein the resistor connects the conducting layer and the metal layer. The invention further concerns use of such sensors use in monitoring and trouble-shooting corrosion impacts.06-12-2014

Alicia Ismach, Netanya IL

Patent application numberDescriptionPublished
20090327133SECURE MECHANISM AND SYSTEM FOR PROCESSING FINANCIAL TRANSACTIONS - A system for secure processing payment transactions between merchants and customers, via financial institutions, the system comprising apparatus for generating global transaction identifiers each of which is recognized by the merchants as a transaction ID and by the financial institutions as a fundable entity, and methods useful in conjunction therewith.12-31-2009

Alicia Langsteiner, Ostrusza PL

Patent application numberDescriptionPublished
20130240583SET OF CONTAINERS AND A METHOD OF CAR BODY REINFORCEMENT - A set of containers comprising containers made of materials able to transfer collision forces, when the car body is hit, where the containers are shaped in relation to each other and in relation to the surfaces limiting the car boot space in such a way that they fill this space completely. The invention refers also to the method of car body reinforcement by filling the car boot with the containers shaped in relation to each other and in relation to the surfaces limiting the car boot space in such a way that they fill this space completely.09-19-2013

Alicia Lasocha, Mogilany PL

Patent application numberDescriptionPublished
20130244866Catalyst For Direct Decomposition of Nitric Oxide And Method of Manufacturing The Catalyst - The oxide catalyst for the direct NO decomposition to N2 and 02 is deposited on the austenitic acid-proof steel substrate and contains the phase with aFe203 structure and the phase with spinel structure and the lattice parameters close to the lattice parameters of NiFe204. Those phases form the micro-crystallites that additionally contain Cr and Mn and eventually Si. The catalyst according to the invention is manufactured by the at least twice heating of the austenitc acid-proof steel substrate in the atmosphere containing oxygen, up to the temperature from the 600-850° C. range, with the rate of 2-6° C./min, followed by the annealing at that temperature for 2-6 hours.09-19-2013

Alicia Le-Sattler, Bochum DE

Patent application numberDescriptionPublished
20130211030PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE POLYMERS - The present invention relates to water and solvent-free polymers, in particular water and solvent-free synthetic rubber products like styrene butadiene rubber products and butadiene rubber products as well as a process for the production thereof. The invention further relates to a device suitable to accomplish said process.08-15-2013
20150252126HIGH-MOONEY NDBR HAVING MOONEY JUMP - The invention relates to methods for achieving a step increase in the Mooney viscosity in production of high-molecular-weight polybutadiene having >95% by weight content of cis-1,4 units and <1% by weight 1,2-vinyl content, characterized in that 09-10-2015

Alicia López Nevot, Granada ES

Patent application numberDescriptionPublished
20150218635METHOD FOR OBTAINING DATA THAT CAN BE USED FOR THE DIAGNOSIS AND PROGNOSIS OF NEUROSENSORY HYPOACUSIS - A method for obtaining useful data for the determination of an individual's risk of suffering from severe sensorineural hearing loss, preferably in Ménière's disease, primers useful in the determination and kit comprising same.08-06-2015

Alicia Moreno-Gonzelez, Redmond, WA US

Patent application numberDescriptionPublished
20140155861EXTRUSION METHODS AND DEVICES FOR DRUG DELIVERY - Disclosed herein are devices and methods for delivering agents to a solid tissue.06-05-2014

Alicia Pompei, Minneapolis, MN US

Patent application numberDescriptionPublished
20110101611TRANSACTION PRODUCT WITH FOLDABLE SHEET - A transaction product includes a first cover panel, a second cover panel, and an intermediate sheet, and an account identifier. The intermediate sheet transitions between a collapsed and an extended position and defines fold lines dividing the intermediate sheet into sections. When the intermediate sheet is in the collapsed position, the sections form a stack. The first cover panel is coupled with one of the sections that forms a top of the stack, and the second cover panel is coupled with another of the sections that forms a bottom of the stack. The account identifier is coupled with at least one of the first and second cover panels and the intermediate sheet and links the transaction product to an account or record configured to track a value available for use toward a purchase of one or more of goods and services. Other products, combinations, and associated methods are also disclosed.05-05-2011
20120274024TRANSACTION PRODUCT WITH FOLDABLE SHEET - A transaction product includes a first cover panel, a second cover panel, and an intermediate sheet, and an account identifier. The intermediate sheet transitions between a collapsed and an extended position and defines fold lines dividing the intermediate sheet into sections. When the intermediate sheet is in the collapsed position, the sections form a stack. The first cover panel is coupled with one of the sections that forms a top of the stack, and the second cover panel is coupled with another of the sections that forms a bottom of the stack. The account identifier is coupled with at least one of the first and second cover panels and the intermediate sheet and links the transaction product to an account or record configured to track a value available for use toward a purchase of one or more of goods and services. Other products, combinations, and associated methods are also disclosed.11-01-2012

Alicia Ponte-Sucre De Vanegas, Wurzburg DE

Patent application numberDescriptionPublished
20100286198Biofilm-Inhibiting Effect and Anti-Infective Activity of N,C- Linked Arylisoquinolines and the Use Thereof - Anti-infective and biofilm-inhibiting activities of aryl isoquinoline-derivatives of the general formulae 1 to 311-11-2010

Alicia Regueiro-Ren, Middletown, CT US

Patent application numberDescriptionPublished
20090306095COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.12-10-2009
20090325985Diketopiperidine Derivatives as HIV Attachment Inhibitors - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, diketopiperidine derivatives that possess unique antiviral activity are provided. These compounds are useful for the treatment of HIV and AIDS.12-31-2009
20100009993Diketo Fused Azolopiperidines and Azolopiperazines as Anti-HIV Agents - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, diketo fused azolopiperidine and azolopiperazine derivatives that possess unique antiviral activity are provided. These compounds are useful for the treatment of HIV and AIDS.01-14-2010
20100093752PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.04-15-2010
20110118279PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.05-19-2011
20110212971DIKETO FUSED AZOLOPIPERIDINES AND AZOLOPIPERAZINES AS ANTI-HIV AGENTS - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, diketo fused azolopiperidine and azolopiperazine derivatives that possess unique antiviral activity are provided. These compounds are useful for the treatment of HIV and AIDS.09-01-2011
20110245268PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.10-06-2011
20120095017PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.04-19-2012
20120142653C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 and C-28 betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.06-07-2012
20120142707MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 betulinic acid and other structurally related natural products derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.06-07-2012
20120238583PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.09-20-2012
20130029954C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-28 amines of C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS. In particular, the following compounds are provided herein, including pharmaceutically acceptable salts thereof:01-31-2013
20130030005PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.01-31-2013
20130035318C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:02-07-2013
20130072465NOVEL BETULINIC ACID DERIVATIVES WITH ANTIVIRAL ACTIVITY - Compounds of Formula I:03-21-2013
20130210787C-3 CYCLOALKENYL TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-3 cycloalkenyl triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV:08-15-2013
20130289046PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.10-31-2013
20130296554C-17 BICYCLIC AMINES OF TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 bicyclic amines of triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:11-07-2013
20140135342PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.05-15-2014
20140221361C-19 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-19 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I and II:08-07-2014
20140243298C-3 ALKYL AND ALKENYL MODIFIED BETULINIC ACID DERIVATIVES - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV:08-28-2014
20140343000COMPOSITIONS HAVING C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:11-20-2014
20150087652PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.03-26-2015
20150259342SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives having the Formula I:09-17-2015
20150291655TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY - Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I:10-15-2015
20150329543PRODRUGS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.11-19-2015
20160075703SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives having the Formula I:03-17-2016

Patent applications by Alicia Regueiro-Ren, Middletown, CT US

Alicia Rodriguez Gascon, Leioa - Vizcaya ES

Patent application numberDescriptionPublished
20120183589Lipid Nanoparticles For Gene Therapy - The present invention relates to a lipid nanoparticle system comprising a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide and, optionally, a positively charged peptide, useful for the release of pharmacologically active molecules, and especially for transfecting genetic material into cells and/or tissues. It also relates to methods for obtaining nanoparticles, to pharmaceutical compositions comprising it, as well as to the use thereof in gene therapy.07-19-2012

Alicia Rodríguez Gascón, Leioa ES

Patent application numberDescriptionPublished
20130324592Lipid Nanoparticles for Treating Ocular Diseases - The present invention relates to the use of a lipid nanoparticle system, where the nanoparticles comprise a nucleic acid, a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide, and optionally a positively charged peptide for the treatment and prevention of eye diseases.12-05-2013

Alicia Roisman-Ismach, Tel Mond IL

Patent application numberDescriptionPublished
20110208600Point of Sale Payment System and Method - A point of sale (POS) payment system does not require the payor to disclose confidential and sensitive financial information to the payee in order to settle the transaction. The payee presents the payor with an invoice or bill. The payor requests from their bank (or proxy for the bank) a payment token for a predefined sum and receives the payment token electronically, such as via smart phone or other portable device. The payment token is transferred to the payee as payment for the invoice. The payee stores the electronic payment token or the data associated therewith and submits the token to the payor bank (or proxy for the bank) to settle the transaction or invoke the settlement process.08-25-2011

Alicia Rufner, Columbia City, IN US

Patent application numberDescriptionPublished
20080319137ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.12-25-2008
20090192610ORTHOPEDIC COMPONENT OF LOW STIFFNESS - An orthopedic component having multiple layers that are selected to provide an overall modulus that is substantially lower than the modulus of known orthopedic components to more closely approximate the modulus of the bone into which the orthopedic component is implanted. In one exemplary embodiment, the orthopedic component is an acetabular shell. For example, the acetabular shell may include an outer layer configured for securement to the natural acetabulum of a patient and an inner layer configured to receive an acetabular liner. The head of a femoral prosthesis articulates against the acetabular liner to replicate the function of a natural hip joint. Alternatively, the inner layer of the acetabular shell may act as an integral acetabular liner against which the head of the femoral prosthesis articulates.07-30-2009
20100022677REDUCTION OF FREE RADICALS IN CROSSLINKED POLYETHYLENE BY INFRARED HEATING - UHMWPE is exposed to crosslinking radiation and than heated utilizing infrared radiation. In one exemplary embodiment, the infrared radiation is provided by an infrared heater having a tungsten heating element with a quartz tube. In this embodiment, the infrared radiation may have the wavelength from about 1.0 micron to about 1.5 microns. In another exemplary embodiment, the UHMWPE is compression molded into bars prior to exposure to the crosslinking radiation.01-28-2010
20100022678REDUCTION OF FREE RADICALS IN CROSSLINKED POLYETHYLENE BY INFRARED HEATING - UHMWPE is exposed to crosslinking radiation and than heated utilizing infrared radiation in an inert environment. In one exemplary embodiment, the infrared radiation is provided by an infrared heater having a tungsten heating element with a quartz tube. In this embodiment, the infrared radiation may have the wavelength from about 1.0 micron to about 1.5 microns. In another exemplary embodiment, the UHMWPE is compression molded into bars prior to exposure to the crosslinking radiation.01-28-2010
20100029858ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.02-04-2010
20110028600ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.02-03-2011
20110133371ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.06-09-2011
20120157591 Antioxidant Stabilized Crosslinked Ultra-High Molecular Weight Polyethylene For Medical Device Applications - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.06-21-2012
20140131925ORTHOPEDIC COMPONENT OF LOW STIFFNESS - An orthopedic component having multiple layers that are selected to provide an overall modulus that is substantially lower than the modulus of known orthopedic components to more closely approximate the modulus of the bone into which the orthopedic component is implanted. In one exemplary embodiment, the orthopedic component is an acetabular shell. For example, the acetabular shell may include an outer layer configured for securement to the natural acetabulum of a patient and an inner layer configured to receive an acetabular liner. The head of a femoral prosthesis articulates against the acetabular liner to replicate the function of a natural hip joint. Alternatively, the inner layer of the acetabular shell may act as an integral acetabular liner against which the head of the femoral prosthesis articulates.05-15-2014
20140194934ANTIOXIDANT STABALIZED CROSSLINKED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.07-10-2014
20140194935ANTIOXIDANT STABILIZED CROSSLINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.07-10-2014
20160108184ANTIOXIDANT STABILIZED CROSSLINKED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE FOR MEDICAL DEVICE APPLICATIONS - An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation, In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.04-21-2016

Patent applications by Alicia Rufner, Columbia City, IN US

Alicia Ruthrauff, Bethlehem, PA US

Patent application numberDescriptionPublished
20150320542COMPOSITE LUMEN WITH REINFORCING TEXTILE AND MATRIX - A composite hollow lumen and a method for producing the lumen are provided. The lumen includes a tubular textile formed of yarns having a first tensile strength and a matrix material in which the tubular textile is embedded to form a conduit having a bore and a sidewall substantially impermeable to liquid. The matrix material has a second tensile strength that is lower than the first tensile strength. The method for producing a composite lumen includes selecting yarns having a first tensile strength, selecting an elastomeric matrix material having a second tensile strength that is lower that the first tensile strength, forming a tubular textile of the yarns, and embedding the tubular textile in the matrix material to form a conduit having a bore and conduit walls that are substantially impermeable to liquid. The elastomeric matrix material is a biodegradable or bioresorbable polyester.11-12-2015

Alicia Sambueli, Buenos Aires AR

Patent application numberDescriptionPublished
20090176244METHODS AND COMPOSITIONS FOR THE DIAGNOSIS OF CROHN'S DISEASE - The present invention provides methods and materials, including kits, to evaluate Crohn's disease, including to diagnose, monitor, or determine the efficacy of treatment for Crohn's Disease. The methods involve determining the presence, absence, or level of zonulin in a subject sample. In certain embodiments, the need for more laborious and/or invasive tests to monitor disease state is minimized or obviated.07-09-2009
20130295594METHODS AND COMPOSITIONS FOR THE DIAGNOSIS OF CROHN'S DISEASE - The present invention provides methods and materials, including kits, to evaluate Crohn's disease, including to diagnose, monitor, or determine the efficacy of treatment for Crohn's Disease. The methods involve determining the presence, absence, or level of zonulin in a subject sample. In certain embodiments, the need for more laborious and/or invasive tests to monitor disease state is minimized or obviated.11-07-2013
20160109444METHODS AND COMPOSITIONS FOR THE DIAGNOSIS OF CROHN'S DISEASE - The present invention provides methods and materials, including kits, to evaluate Crohn's disease, including to diagnose, monitor, or determine the efficacy of treatment for Crohn's Disease. The methods involve determining the presence, absence, or level of zonulin in a subject sample. In certain embodiments, the need for more laborious and/or invasive tests to monitor disease state is minimized or obviated.04-21-2016

Patent applications by Alicia Sambueli, Buenos Aires AR

Alicia Santos Savio, Ciudad De La Habana CU

Patent application numberDescriptionPublished
20090005294Peptides for the Treatment of Cancer Associated with the Human Papilloma Virus (HPV) and Other Epithelial Tumors - This invention is related to the Molecular Pharmacology field and especially to the development of peptides useful for treating epithelial tumors and mainly those associated to oncogenic types of HPVs. The main objective of this invention is to identify peptides whose structure permits to block the Casein Kinase II (CKII) phosphorylation domain by direct interaction with such a site. In the present invention it is shown eleven cyclic peptides with different aminoacid sequences which inhibit the CKII phosphorylation in vitro, exhibit cytotoxicity on HPV-16 transformed cells (CaSki) and also increase the sensitivity of these cells to the cytostatic effect of interferon (IFN). Furthermore, the invention relates to the use of these peptides conjugated or fused to other peptides and chemical compounds which penetrates into cells as well as with the use of both peptide and chemical mimetic molecules.01-01-2009
20090136511Interleukin-15 Antagonist Peptide - Current invention is related to the molecular pharmacology branch particularly to a peptide belonging to the Interleukin-15 sequence (IL-15) which is able to inhibit IL-15 biological activity, analogues or mimetic of such peptides. In the current invention it is shown that the peptide inhibits both IL-15-induced T cells proliferation upon binding to the IL15 receptor α subunit (IL15Rα) and TNFα-mediated apoptosis.05-28-2009
20110251140PEPTIDE ANTAGONIST OF INTERLEUKIN-15 ACTIVITY - The present invention is related to the field of molecular immunology, particularly to a peptide derived from the sequence of interleukine-15 (IL-15), wherein said peptide was optimized to inhibit the biological activity of this molecule. In the present invention, it is shown that this peptide inhibits IL-15-induced T cell proliferation, Tumor Necrosis Factor α (TNFα) induction and the expression of IL-8 and IL-6 by the IL-15 receptor a subunit (IL-15Rα), all these effects mediated by the binding of the peptide to the IL-15Rα. The invention is also related to the use of the peptide to treat pathologies where the abnormal expression of IL-15 or IL-15Rα is related to the course of the disease, such as rheumatoid arthritis (RA) and prostate cancer.10-13-2011

Patent applications by Alicia Santos Savio, Ciudad De La Habana CU

Alicia Scheffer-Wong, San Jose, CA US

Patent application numberDescriptionPublished
20150148239SPATIAL MOLECULAR BARCODING OF IN SITU NUCLEIC ACIDS - This disclosure provides, among other things, a method for analyzing a planar cellular sample. In some embodiments, the method comprises: (a) indirectly or directly attaching nucleic acid tags to binding sites in a planar cellular sample; (b) contacting the planar cellular sample with a solid support comprising an array of spatially addressed features that comprise oligonucleotides, wherein each oligonucleotide comprises a molecular barcode that identifies the feature in which the oligonucleotides is present; (c) hybridizing the nucleic acid tags, or a copy of the same, with the oligonucleotides to produce duplexes; and (d) extending the oligonucleotides in the duplexes to produce extension products that each comprises (i) a molecular barcode and (ii) a copy of a nucleic acid tag. Other embodiments, e.g., kits and the like, are also described.05-28-2015

Alicia Scheffer-Wong, Santa Clara, CA US

Patent application numberDescriptionPublished
20150367345CONTINUOUS FLOW CENTRIFUGAL MICROFLUIDIC PARTICLE CONCENTRATOR, AND RELATED METHODS - A microfluidic disk for concentrating particles includes a plurality of distribution channels and separation channels. A sample fluid is flowed through the distribution channels while the disk is spun. Particles of the sample fluid flow into the separation channels where they accumulate. The particles in the separation channels may be subjected to an analysis.12-24-2015

Alicia Suminski, Paris FR

Patent application numberDescriptionPublished
20140188686AUCTIONING MECHANISMS FOR DARK ORDER BLOCK TRADING - Auctioning mechanisms adapted to improve the integrity of dark order block trading is provided.07-03-2014
20140188693AUCTIONING MECHANISMS FOR DARK ORDER BLOCK TRADING - Auctioning mechanisms adapted to improve the integrity of dark order block trading is provided.07-03-2014
20150073974AUCTIONING MECHANISMS FOR DARK ORDER BLOCK TRADING - Auctioning mechanisms adapted to improve the integrity of dark order block trading is provided.03-12-2015
20150095208AUCTIONING MECHANISMS FOR DARK ORDER BLOCK TRADING - Auctioning mechanisms adapted to improve the integrity of dark order block trading is provided.04-02-2015

Alicia Valero Masa, Bilbao ES

Patent application numberDescriptionPublished
20150247891Detection of High Impedance Faults - A method detects a high-impedance fault occurring in an electric distribution circuit that distributes a three-phase alternating current. The method includes the steps of applying a plurality of electrical signal analysis techniques that provide a plurality of fault detection indicators, and generating a signal that indicates a high-impedance fault depending on the outcome of the fault detection indicators. The method is characterized by determining a randomness of the residual current of the three-phase alternating current prior to determining the plurality of fault detection indicators, and generating a trigger signal depending on the randomness of the residual current. The step of determining the plurality of fault detection indicators requires that the trigger signal has been generated.09-03-2015

Alicia Wang, Wappingers Falls, NY US

Patent application numberDescriptionPublished
20100301446IN-LINE STACKING OF TRANSISTORS FOR SOFT ERROR RATE HARDENING - Each one of a pair of CMOS transistors is formed in its own island and a gate terminal for each transistor is formed by a single, in-line conductor connecting both gate terminals together. This type of “in-line” connection achieves nearly a five-time improvement in the reduction of the ability of ionizing radiation particles to strike both transistors at the same time as compared to prior art “side-by-side” transistor stacking through use of a relatively smaller solid angle spanning the two transistors. This results in “hardening” of the transistors and improving their resistance to single event upsets and, thus, improving the soft error rate (SER) of the transistors.12-02-2010
20100301463REDUCED SOFT ERROR RATE THROUGH METAL FILL AND PLACEMENT - A method for reducing single event upsets in an integrated circuit includes the step of providing a plurality of levels within the integrated circuit, wherein the plurality of levels within the integrated circuit are in a stacked arrangement. The method also includes the step of providing a plurality of metal fill patterns within each of the plurality of levels within the integrated circuit. The method further includes the step of placing the plurality of metal fill patterns within at least one of the plurality of levels in a pattern such that a line of sight towards an active silicon layer does not exist within the stacked arrangement of the plurality of levels, thereby increasingly absorbing ionizing radiation particles, and thereby reducing single event upsets in the integrated circuit.12-02-2010

Alicia Wong, Antioch, CA US

Patent application numberDescriptionPublished
20120002857HYBRID DUAL-MODALITY IMAGE PROCESSING SYSTEM AND METHOD - Hybrid dual-modality image processing systems and methods are disclosed. For example, an image processing system includes a computer for processing SPECT tomographic projection data and a CT volume image. The computer derives a SPECT transverse volume image from the projection data and registers the SPECT transverse volume image with the CT volume image to obtain an attenuation map and registration information. The computer uses the attenuation map and the registration information to derive a SPECT transverse volume image with attenuation correction. The computer uses the registration information to derive a SPECT transverse volume image without attenuation correction. The SPECT transverse volume images, with and without attenuation correction, are derived at or near the same time, using the same registration information. The registration information is stored in, carried by, or otherwise communicated through the attenuation map for subsequent processing of the SPECT transverse volume images.01-05-2012
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