Noriaki Tanaka
Noriaki Tanaka, Okayama JP
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20080206733 | Method of Inducing Differentiation of Embryo-Stem Cell Into Hepatocyte and Hepatocyte Induced by the Method - With respect to a method for differentially inducing embryo-stem cells into hepatocytes, in order to obtain safe hepatocytes that are adequately functionable and able to supply in large quantity, a method for differentially inducing embryo-stem cell into hepatocyte, wherein the embryo-stem cells are cultured in the presence of deletion type hepatocyte growth factor is provided. Further, a method for differentially inducing embryo-stem cells into hepatocytes comprising (a) a step of forming the embryoid body of the embryo-stem cells and (b) a step of culturing the embryoid body in the presence of deletion type hepatocyte growth factor is provided. | 08-28-2008 |
20090148424 | Reversibly immortalized mammalian liver cells and use thereof - The present invention provides a reversibly immortalized mammalian liver cell line, especially CYNK-1 (deposited with International Patent Organism Depository, National Institute of Advanced Industrial Science and Technology, address: AIST Tsukuba Central 6, 1-1, Higashi 1-Chome, Tsukuba-shi, Ibaraki-ken, 305-8566 Japan, deposited date: Mar. 10, 2004, accession number: FERM BP-08657) comprising an immortalizing gene interposed between a pair of site-specific recombination sequences and a suicide gene in the outside of the pair of site-specific recombination sequences, characterized in that the suicide gene can exhibit its function after excision of the pair of site-specific recombination sequences, or passage cell line thereof; a mammalian liver cell obtained by excising the immortalizing gene from the reversibly immortalized mammalian liver cell line or passage cell line thereof; and use of these cells. By utilizing the reversibly immortalized mammalian liver cell line of the present invention enables the obtainment of the number of the liver cells and utilization as materials for artificial liver reactors and cell preparations. | 06-11-2009 |
20090221068 | Cell Cultivation Method and Cell Culture - Provided is a cell cultivation method in which the cell is cultured using a peptide hydrogel as a scaffold, for carrying out high-dimensional culture of a cell such as porcine hepatocyte, human hepatocyte, porcine pancreatic islet or human pancreatic islet for a long period under conditions where cell survival, cell morphology and cell functions are maintained. Also provided are a cell culture including a cell and a peptide hydrogel obtained by the above-described cultivation method, a bioreactor including the cell culture, and a cell preparation including the cell culture. | 09-03-2009 |
20110065117 | Mesothelioma Specific Transferred Promoter And Use Thereof - Provided is a promoter showing transcriptional activity in a mesothelioma-specific manner and showing low transcriptional activity in other kinds of cancer cells and normal cells including mesothelium. Also provided are applications of the promoter, and more specifically, a gene therapy vector and a therapeutic agent for mesothelioma each including the promoter. The promoter includes a CRI1 gene-derived promoter, which is one kind of mesothelioma markers. The use of a vector including a cell death-inducing gene or a cell lysis-inducing gene as a transgene and carrying the CRI1 gene-derived promoter upstream of the transgene can induce a cell death or cell lysis action in a mesothelioma-specific manner. That is, the gene therapy vector and the therapeutic agent for mesothelioma each include a virus vector carrying the CRI1 gene-derived promoter. | 03-17-2011 |
20110097714 | AMPLIFICATION METHOD OF METHYLATED OR UNMETHYLATED NUCLEIC ACID - The object of the present invention is to provide a gene amplification method, wherein the method can amplify both methylated and unmethylated nucleic acids present in a biological sample, and further regulate the amplification ratio of the methylated and/or unmethylated nucleic acid as needed. Such objects can be solved by an amplification method using a nonspecific primer which can hybridize both with methylated and unmethylated nucleic acids and a specific primer which specifically hybridizes with either methylated or unmethylated nucleic acid, and further by an amplification method which can change the amplification ratio of methylated or unmethylated nucleic acid by changing the mixing rate of these primers. | 04-28-2011 |
Noriaki Tanaka, Tottori JP
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20110044949 | ONCOLYTIC VIRUS REPLICATING SELECTIVELY IN TUMOR CELLS - By using a virus having a gene sequence comprising a telomerase promoter and an E1 gene (preferably a sequence comprising E1A gene, IRES sequence and E1B gene) or by using an anticancer agent comprising the virus, the virus replicates in cancer cells to thereby produce an efficient anticancer effect. | 02-24-2011 |
20110111480 | Telomelysin/GFP-expressing recombinant virus - The present invention provides a reagent for cancer cell detection or cancer diagnosis. The present invention relates to a reagent for cancer cell detection, comprising a recombinant virus where a replication cassette comprising a promoter from human telomerase, an E1A gene, an IRES sequence and an E1B gene in this order is integrated in E1 region of the viral genome and a labeling cassette comprising a gene encoding a labeling protein and a promoter capable of regulating the expression of the gene encoding the labeling protein is integrated in E3 region of the viral genome. | 05-12-2011 |
Noriaki Tanaka, Sendai JP
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20100315037 | RESISTOR TESTING CIRCUIT AND BATTERY CHARGER INCLUDING RESISTOR TESTING CIRCUIT - A resistor testing circuit for a battery charger that tests divisional resistors used to estimate the resistance of a thermistor in a battery pack. The battery charger when activated conducts a self test. In the self test, switches are sequentially switched to form groups of resistors and test the connection state of the resistors groups. When a defect is detected by the self test, the battery charger stops performing charging. When no defects are detected by the self test, the thermistor of the battery pack is used to estimate temperature. The charging current is determined in correspondence with the temperature. Then, charging is started. | 12-16-2010 |
Noriaki Tanaka, Kanagawa JP
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20100238473 | DRAWING PROCESSING APPARATUS, IMAGE OUTPUTTING APPARATUS, METHOD FOR DRAWING PROCESSING AND COMPUTER READABLE MEDIUM - A drawing processing apparatus is provided and includes: a plurality of character definition information memories each storing definition information on a character shape; a registering portion that, when a drawing command containing the definition information on the character shape is received, determines one of the plurality of character definition information memories for each character contained in the drawing command, depending on whether the definition information on the character shape is simple definition information that defines the character shape itself of the character or is a combinational definition information that defines a combination of simple or combinational definition information defining components of the character; and a drawing process instructing portion that instructs to read, from the plurality of character definition information memories, the definition information on the character shape corresponding to the character to be processed, to execute a drawing process of the each character contained in the drawing command. | 09-23-2010 |
20150019393 | INFORMATION PROCESSING APPARATUS AND METHOD, AND NON-TRANSITORY COMPUTER READABLE MEDIUM - An information processing apparatus includes an obtaining unit, a calculator, and an output unit. The obtaining unit obtains fee information indicating a fee of a service used by multiple users. The calculator calculates a distributed price to be charged to each of the multiple users if the fee indicated by the fee information obtained by the obtaining unit is distributed among the multiple users. The output unit outputs data indicating distributed prices calculated by the calculator and items of identification information for identifying the multiple users to which the distributed prices are charged. | 01-15-2015 |
Noriaki Tanaka, Okayama-Shi JP
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20100150884 | Anticancer Agent to Be Combined with Telomelysin - The present invention relates to providing a pharmaceutical composition with a still more enhanced anticancer activity. Specifically, the present invention relates to a pharmaceutical composition for combination therapy for tumors, comprising a recombinant virus comprising a polynucleotide containing a promoter for human telomerase, an E1A gene, an IRES sequence and an E1B gene in this order, and a substance having an antitumor effect. | 06-17-2010 |
20130029415 | CELL CULTIVATION METHOD AND CELL CULTURE - Provided is a cell cultivation method in which the cell is cultured using a peptide hydrogel as a scaffold, for carrying out high-dimensional culture of a cell such as porcine hepatocyte, human hepatocyte, porcine pancreatic islet or human pancreatic islet for a long period under conditions where cell survival, cell morphology and cell functions are maintained. Also provided are a cell culture including a cell and a peptide hydrogel obtained by the above-described cultivation method, a bioreactor including the cell culture, and a cell preparation including the cell culture. | 01-31-2013 |
20140377862 | CELL CULTIVATION METHOD AND CELL CULTURE - Provided is a cell cultivation method in which the cell is cultured using a peptide hydrogel as a scaffold, for carrying out high-dimensional culture of a cell such as porcine hepatocyte, human hepatocyte, porcine pancreatic islet or human pancreatic islet for a long period under conditions where cell survival, cell morphology and cell functions are maintained. Also provided are a cell culture including a cell and a peptide hydrogel obtained by the above-described cultivation method, a bioreactor including the cell culture, and a cell preparation including the cell culture. | 12-25-2014 |
Noriaki Tanaka, Suntou-Gun JP
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20100080623 | ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS - An electrophotographic image forming apparatus includes a cartridge supporting member movable between an inside position inside the main assembly of the apparatus and an outside position outside the main assembly, a light source, a light guide member, on the cartridge supporting member, for guiding the light from the light source to electrically discharge charge remaining on a drum after a developed image on the drum is transferred onto recording material when the cartridge is in an image forming position, an interrelating member for moving the light source to an operating position where the light enters the light guide member in interrelation with movement of the cartridge supporting member from the outside to the inside positions, and a positioning member positioning the light source at the operating position. | 04-01-2010 |
20100104326 | IMAGE FORMING APPARATUS - An image forming apparatus includes a cartridge including at least one of an image bearing member and a developing device; a main assembly including an opening; an openable member movable between a closed position in which the opening is covered and an open position in which the opening is exposed; and a movable member for supporting the cartridge. The movable member is movable between an inside position in which the cartridge is located inside the main assembly and a pulled out position in which the movable member is outwardly pulled out from the main assembly. The openable member is prevented, from moving from the open position to the closed position, in a state in which the movable member is located outside the open position but is movable from the open position to the closed position in a state in which the movable member is located at the open position. | 04-29-2010 |
Noriaki Tanaka, Asakuchi-Gun JP
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20080233642 | MAMMALIAN IMMORTALIZED LIVER CELL - The present invention provides a mammalian immortalized liver cell obtained by transferring a cell proliferation factor gene located between a pair of site-specific recombination sequences into a mammalian liver cell. | 09-25-2008 |
20090209033 | Immortalized hepatocyte cell line secreting modified insulin with glucose sensitivity - The present invention provides a cell line which can be substituted for β cells in human mature pancreatic islets and express insulin in a glucose-concentration dependent manner, and enables the easy obtainment of the number of cells which meets the demand. The present invention also provides a therapeutical cell preparation for treating diabetes. The cell lines of the present invention can be obtained by integrating both a nucleotide sequence encoding tamoxifen-induced Cre recombinase and a nucleotide sequence encoding insulin regulated by glucose-sensitive promoter into the chromosome in a human immortalized hepatic cell line FERM BP-7498 containing the TERT gene inserted in between a pair of LoxP sequences. | 08-20-2009 |
Noriaki Tanaka, Kakamigahara-Shi JP
Noriaki Tanaka, Sakai-Shi JP
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20130068945 | METHOD FOR DETERMINING STAGE OF CHRONIC KIDNEY DISEASE, DEVICE THEREFOR AND METHOD FOR OPERATING THE SAME - This invention provides a method or device for determining the stage of chronic kidney disease. | 03-21-2013 |
Noriaki Tanaka, Atsugi JP
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20130300510 | OSCILLATING DEVICE AND ELECTRONIC APPARATUS - An oscillating device includes an atomic oscillator, an oven controlled crystal oscillator, a correcting unit configured to correct an output signal of the oven controlled crystal oscillator on the basis of an output signal of the atomic oscillator, a housing configured to house the atomic oscillator and the oven controlled crystal oscillator, and a temperature adjusting unit configured to adjust the temperature in the housing to a predetermined temperature. | 11-14-2013 |
Noriaki Tanaka, Chino JP
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20140203963 | TIMING SIGNAL GENERATING DEVICE, ELECTRONIC APPARATUS, MOVING OBJECT, METHOD OF GENERATING TIMING SIGNALS, AND METHOD OF CONTROLLING SATELLITE SIGNAL RECEIVER - A timing signal generating device includes a GPS receiver and a processing unit. The GPS receiver functions as a positioning calculation unit, and receives satellite signals transmitted from GPS satellites and performs positioning calculation based on trajectory information and time information contained in the received satellite signals. Further, the processing unit functions as a position information generation unit, and generates position information of a receiving point based on a mode value or a median value in results of the positioning calculation at a plurality of times by the GPS receiver. | 07-24-2014 |