Oldinski
Rachael Oldinski, Colchester, VT US
Patent application number | Description | Published |
---|---|---|
20160067378 | DECELLULARIZATION AND RECELLULARIZATION OF WHOLE ORGANS - The present invention provides systems and methods for the decellularization and recellularization of tissue segments. In certain instances the invention comprises coating or sealing decellularized tissue segments with a cross-linked alginate hydrogel. The present invention also provides a decellularization kit, which may be used to generate decellularized tissue segments for high throughput studies. Also included are compositions and methods of tissue sealants comprising methacrylated alginate. | 03-10-2016 |
Rachael Kurkowski Oldinski, Fort Collins, CO US
Patent application number | Description | Published |
---|---|---|
20080318022 | Outer layer material having entanglement of hydrophobic polymer host blended with a maleated hydrophobic polymer co-host, and hydrophilic polymer guest - An outer layer material having an entanglement comprising an intermingling of cloaked hydrophilic guest and a hydrophobic polymer host, wherein molecules of the guest have been crosslinked with each other. Under certain circumstances, using complexes of the guest may be desirable or even necessary. Prior to intermingling with the guest, a host blend may be produced to include a physical blend of a hydrophobic polymer host and a maleated hydrophobic co-host (preferably, an anhydride functionalized hydrophobic polymer, whereby the polymer so functionalized, is the same as that selected for the host). The intermingling of the guest and host, or host-co-host blend, includes a physical tangling, whether it also comprises crosslinking by primary bonding (e.g., chemical/covalent bonding) there-between. Also a method of producing an outer layer material having such an entanglement, including the steps of: temporarily cloaking at least a portion of the hydrophilic groups of the guest; intermingling at least a portion of the cloaked groups with a porous polymeric structure by diffusing the guest with cloaked groups into at least a portion of the structure's pores; within the pores, crosslinking at least a portion of the molecules of the guest with the guest; and removing the cloaking. Cloaking may be performed by silylation or acylation. Intermingling may be performed by producing a mixture of guest and host, or host blend, (whether in solution, powdered, granular, etc., form); next, a crosslinking of the guest with itself is performed; then, the mixture is molded into the outer layer with or without additional crosslinking of the host to the host. | 12-25-2008 |
Rachael Kurkowski Oldinski, Seattle, WA US
Patent application number | Description | Published |
---|---|---|
20130197160 | COPOLYMER SYNTHESIZED FROM A MODIFIED GLYCOSAMINOGLYCAN (GAG) AND AN ANHYDRIDE FUNCTIONALIZED HYDROPHOBIC POLYMER - A new copolymer synthesized from a glycosaminoglycan (GAG) such as hyaluronan/hyaluronic acid (HA), chondroitin sulfates, derma tan sulfates, keratan sulfates, heparan sulfate, and heparin, and an anhydride functionalized hydrophobic polymer, i.e., any polyolefin which has been ‘functionalized’ (grafted onto the backbone or incorporated into the backbone) with anhydride functional groups, such as maleic anhydride-graft-polyethylene, (or, maleated polyethylene), maleic anhydride-graft-polystyrene, maleic anhydride-graft-polypropylene, etc. The functionalized polyolefin may be a polyolefin backbone to which the anhydride functional groups have been grafted, or otherwise incorporated with the backbone. Also, a unique synthesis technique combines a modified GAG with a graft polyolefin, resulting in a unique copolymer with its constituents by-and-large covalently bound to each other. | 08-01-2013 |
20140094568 | OUTER LAYER HAVING ENTANGLEMENT OF HYDROPHOBIC POLYMER HOST BLENDED WITH A MALEATED HYDROPHOBIC POLYMER CO-HOST, AND HYDROPHILIC POLYMER GUEST - The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a hydrophilic guest, including in one embodiment the steps of: intermingling cloaked hydrophilic guest complexes with the hydrophobic host; crosslinking molecules of the guest with the guest; and performing a hydrolysis reaction. | 04-03-2014 |
Robert Oldinski, Bay City, MI US
Patent application number | Description | Published |
---|---|---|
20090215959 | FLUOROPLASTIC SILICONE VULCANIZATES - Fluoroplastics containing fluorocarbon resins and silicones are prepared by first mixing a fluorocarbon resin with a compatibilizer, then adding a curable organopolysiloxane with a radical initiator, and vulcanizing the organopolysiloxane in the mixture. The fluoroplastics can be processed by various techniques, such as extrusion, vacuum forming, injection molding, blow molding or compression molding, to fabricate plastic parts. The resulting fabricated parts can be re-processed (recycled) with little or no degradation of mechanical properties. | 08-27-2009 |
Robert Leo Oldinski, Bay City, MI US
Patent application number | Description | Published |
---|---|---|
20130074919 | ACTUATABLE PUNCH ASSEMBLY, METHOD OF USING SAME, AND A LAMINATE PREPARED THEREBY - An actuatable punch assembly forms a hole within an article. The actuatable punch assembly comprises a base plate coupled to the actuator. At least one segment block is adjustably coupled to the base plate. At least one cutting device for forming the hole within the article is coupled to the segment block. The segment block is adjustable relative to the base plate. The cutting device is adjustable relative to the segment block. As such, the cutting device is adjustable relative to the base plate for varying a position of the cutting device relative to the article to vary a size of the hole formed in the article. | 03-28-2013 |