Williams, Cambridge
Andrea Williams, Cambridge GB
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20100113379 | cAMP DEPENDENT INDUCTION OF AUTOPHAGY - The present invention relates to the induction of autophagy via mTOR independent pathways which modulated intracytosolic cAMP levels. In some embodiments, autophagy may be induced in a cell by reducing intracytosolic cAMP levels, for example using a cAMP antagonist, such as clonidine. This may be useful, for example in the treatment of neurodegenerative disorders or pathogen infections. | 05-06-2010 |
Brandon Williams, Cambridge, MA US
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20140082217 | Peer-to-peer connection establishment using TURN - A relay service enables two peers attempting to communicate with one another to each connect to a publicly-accessible relay server, which servers are associated with an overlay network and are selected by a directory service. After end-to-end connectivity is established, preferably the hosts communicate with each other by relaying data packets via the overlay network relay servers. Communications (both connection control messages and data being relayed) between a host and a relay server occurs at an application layer using a modified version of the TURN protocol. | 03-20-2014 |
20150381566 | Peer-to-peer connection establishment using TURN - A relay service enables two peers attempting to communicate with one another to each connect to a publicly-accessible relay server, which servers are associated with an overlay network and are selected by a directory service. After end-to-end connectivity is established, preferably the hosts communicate with each other by relaying data packets via the overlay network relay servers. Communications (both connection control messages and data being relayed) between a host and a relay server occurs at an application layer using a modified version of the TURN protocol. | 12-31-2015 |
Brian John Williams, Cambridge GB
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20110046155 | HYDROBENZAMIDE DERIVATIVES AS INHIBITORS OF HSP90 - The invention provides an acid addition salt of a compound of the formula (1) Also provided by the invention are processes for preparing the compound of formula (1) and alkyl analogues thereof, novel intermediates for use in the process and methods for preparing the intermediates. The invention also provides new medical uses of compounds of the formula (1) and its ethyl analogue. | 02-24-2011 |
20110098290 | PHARMACEUTICAL COMPOUNDS - The invention provides a compound of the formula (1): | 04-28-2011 |
20130210820 | Pharmaceutical Compounds - The invention provides a compound of the formula (1): | 08-15-2013 |
20140221394 | HYDROBENZAMIDE DERIVATIVES AS INHIBITORS OF HSP90 - The invention provides an acid addition salt of a compound of the formula ( | 08-07-2014 |
David Arfon Williams, Cambridge GB
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20090080118 | EMR SENSOR WITH INTEGRATED SIGNAL AMPLIFICATION - A Lorentz magnetoresistive sensor having integrated signal amplification. The sensor is constructed upon a substrate such as a semiconductor material, and an amplification circuit such as transistor is constructed directly into the substrate on which the magnetoresistive device is constructed. This integrated signal amplification greatly enhances sensor performance by eliminating a great deal of signal noise that would otherwise be added to the read signal. | 03-26-2009 |
David Hugh Williams, Cambridge GB
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20140135234 | METHOD FOR IDENTIFYING ANTIBIOTIC TARGETS BY COMPLEMENTED SEQUENCING - Disclosed is a method for identifying an essential gene which serves as an antibiotic target in a bacterium, the method comprising the steps of: | 05-15-2014 |
20140141979 | METHOD FOR IDENTIFYING ANTIBIOTIC TARGETS - Disclosed is a method for identifying an essential gene which serves as an antibiotic target in a bacterium, the method comprising the steps of: | 05-22-2014 |
Emelio Williams, Cambridge, MA US
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20130282928 | WIRELESS ADAPTER FOR CONNECTING A COMPUTING DEVICE DIRECTLY TO A NON-MASTER PERIPHERAL DEVICE WITH LEGACY INTERFACE AND METHOD OF USE - A wireless adapter and method of using the adapter for wireless connection via communication protocols, communication and data exchange between non-master peripheral devices that have legacy interface such as legacy wired serial computer interfaces and computing devices. The wireless adapter includes a wireless module such as a radio transmission/reception module that supports one or more wireless interfaces and has embedded software stack with at least one or several communication protocols. The wireless module is connected to a microprocessor emulating role of a master device. The adapter interface connector plugs into the legacy interface connector of the non-master peripheral device. The microprocessor emulates a master device in legacy interface in combination with a voltage regulator/converter so the wireless adapter plays a role of a master device in legacy interface with the non-master peripheral device acting as a non-master device in interface. This establishes a wireless connection between the computing device and the non-master peripheral device across the wireless adapter. | 10-24-2013 |
Gareth H. Williams, Cambridge GB
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20100143943 | DETECTION OF DYSPLASTIC OR NEOPLASTIC CELLS USING ANTI-MCM2 ANTIBODIES - Determination of cellular growth abnormality, particularly cancerous abnormality, by detection of target polypeptides or encoding mRNA, where the target polypeptides are members of the preinitiation complex of DNA replication in tissue, cells or fluid. Target polypeptides include CDC6, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Test samples include tissue of the cervix (both biopsy and smear samples), breast, colon, lung, bladder, skin, larynx, oesophagus, bronchus, lymph nodes and urinary tract (both biopsy and cytology smear samples), in determination of cancerous and pre-cancerous cellular growth abnormality, and cells spun from urine, blood and serum, in determination of haematological malignancies and evidence of metastatic sarcoma and carcinoma. | 06-10-2010 |
20120178103 | DETECTION OF DYSPLASTIC OR NEOPLASTIC CELLS USING ANTI-MCM6 ANTIBODIES - Determination of cellular growth abnormality, particularly cancerous abnormality, by detection of target polypeptides or encoding mRNA, where the target polypeptides are members of the preinitiation complex of DNA replication in tissue, cells or fluid. Target polypeptides include CDC6, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Test samples include tissue of the cervix (both biopsy and smear samples), breast, colon, lung, bladder, skin, larynx, oesophagus, bronchus, lymph nodes and urinary tract (both biopsy and cytology smear samples), in determination of cancerous and pre-cancerous cellular growth abnormality, and cells spun from urine, blood and serum, in determination of haematological malignancies and evidence of metastatic sarcoma and carcinoma. | 07-12-2012 |
20130273577 | DETECTION OF DYSPLASTIC OR NEOPLASTIC CELLS USING ANTI-MCM3 ANTIBODIES - Determination of cellular growth abnormality, particularly cancerous abnormality, by detection of target polypeptides or encoding mRNA, where the target polypeptides are members of the preinitiation complex of DNA replication in tissue, cells or fluid. Target polypeptides include CDC6, MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7. Test samples include tissue of the cervix (both biopsy and smear samples), breast, colon, lung, bladder, skin, larynx, oesophagus, bronchus, lymph nodes and urinary tract (both biopsy and cytology smear samples), in determination of cancerous and pre-cancerous cellular growth abnormality, and cells spun from urine, blood and serum, in determination of haematological malignancies and evidence of metastatic sarcoma and carcinoma. | 10-17-2013 |
Jared Williams, Cambridge, MA US
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20160078455 | METHOD OF ENHANCING CUSTOMER RELATIONSHIP MANAGEMENT CONTENT AND WORKFLOW - Forward-looking sales activities are poorly served by existing Customer Relationship Managements systems, as the customer information those systems maintain by definition does not include the speculatively interested “leads” pursued in initial sales contacts. An Enrichment database, asynchronously loaded with corporate and optionally individual contact information in anticipation of use, provides real-time access to information in support of such first customer contacts. The Enrichment information may also be used to expedite creation and revision of CRM records. | 03-17-2016 |
Jason Geraint Seaborne Williams, Cambridge GB
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20100264335 | PATTERN WRITING ON A ROTATING SUBSTRATE - A method of producing an array of islands ( | 10-21-2010 |
Jonathan Tyson Williams, Cambridge GB
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20140192692 | Power Saving for a Communication Device - A communication device comprising: a first radio capable of communicating according to a first protocol and having a set of operational modes; and a second radio capable of communicating according to a second protocol, the communication device being configured to, in dependence on one or more communications by the second radio in accordance with the second protocol, selecting one mode of operation for the first radio from the set of operational modes, wherein said one or more communications comprises: sending a first message; and a response or non-response to the first message. | 07-10-2014 |
Lyndsay Williams, Cambridge GB
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20080317386 | Playback of Digital Images - A method of displaying digital images is described in which a display length indicator is received and digital images are accessed. A set of digital images are selected from the accessed digital images in accordance with the display length indicator and displayed in a predetermined order. The method may be performed by a computer program, which may be embodied on a computer readable medium. | 12-25-2008 |
20090153526 | DETERMINING THE LOCATION OF THE TIP OF AN ELECTRONIC STYLUS - An electronic stylus system includes an electronic stylus and base receiving unit. The electronic stylus includes a first ultrasonic transmitter, a second ultrasonic transmitter, an electromagnetic transmitter, and a writing tip. The base receiver unit includes a first ultrasonic receiver, a second ultrasonic receiver, and an electromagnetic receiver. The ultrasonic receivers of the base unit are operable to receive signals transmitted by the ultrasonic transmitters of the electronic stylus. Similarly, the electromagnetic receiver of the base unit is operable to receive signals transmitted by the electromagnetic transmitter of the stylus. The location of the tip of the electronic stylus relative to a given reference point is determined using the locations of two ultrasonic transmitters relative to the two ultrasonic receivers. | 06-18-2009 |
20090191824 | METHODS AND APPARATUS FOR TRANSMITTING POWER AND DATA USING THE HUMAN BODY - Methods and apparatus for distributing power and data to devices coupled to the human body are described. The human body is used as a conductive medium, e.g., a bus, over which power and/or data is distributed. Power is distributed by coupling a power source to the human body via a first set of electrodes. One or more devices to be powered, e.g., peripheral devices, are also coupled to the human body via additional sets of electrodes. The devices may be, e.g., a speaker, display, watch, keyboard, etc. A pulsed DC signal or AC signal may be used as the power source. By using multiple power supply signals of differing frequencies, different devices can be selectively 15 powered. For example, a 100 Hz signal may be used to power a first device while a 150 Hz signal may be used to power a second device. Digital data and/or other information signals, e.g., audio signals, can be modulated on the power signal using frequency and/or amplitude modulation techniques. The power source and peripheral devices can interact to form a complete computer network where the body serves as the bus coupling the devices together. Devices can include optional batteries, one or more CPUs, transmit/receive circuitry, and/or input/output circuitry. In one particular exemplary network implementation the first device to be placed on the body operates as a master device, e.g., bus master, with one or more subsequently added devices working as slaves. | 07-30-2009 |
20090284611 | Transferring of Digital Images - A method of transferring images from a first device to a second device and computer program code for performing this method is described. A connection characteristic for a connection between the first & second devices is determined and at least one image is selected from a plurality of images on the first device for transfer dependent upon both the connection characteristic and image selection criteria. The selected image(s) are then transferred over the connection from the first device to the second device. | 11-19-2009 |
20100171846 | Automatic Capture Modes - An image capture device is described which is operable in any one of a number of capture modes. The device comprises a camera, a memory and a processor. The memory stores a plurality of sets of capture triggers, with each set of capture triggers being associated with one of the plurality of capture modes. The processor selects one of the plurality of capture modes, such that the device is operable in the selected capture mode. In the selected capture mode, an image is captured automatically when a capture trigger within the associated set of capture triggers is satisfied. | 07-08-2010 |
20150086177 | RECALL DEVICE - A small wearable recall device is provided to capture images triggered by a combination of a detection of a capture condition (e.g., changes in motion, temperature or light level) followed by a relatively stable period, as detected by an accelerometer. By triggering on the combination of a detected capture condition followed by a detected stability condition, a clearer image of the environment of an interesting event is expected to be captured. The small size of the recall device makes it possible to integrate it into common portable consumer products, such as MP3 players, purses, clothing, hats, backpacks, necklaces, collars, and other human-wearable products. | 03-26-2015 |
Marian Williams, Cambridge GB
Patent application number | Description | Published |
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20110046155 | HYDROBENZAMIDE DERIVATIVES AS INHIBITORS OF HSP90 - The invention provides an acid addition salt of a compound of the formula (1) Also provided by the invention are processes for preparing the compound of formula (1) and alkyl analogues thereof, novel intermediates for use in the process and methods for preparing the intermediates. The invention also provides new medical uses of compounds of the formula (1) and its ethyl analogue. | 02-24-2011 |
20110098290 | PHARMACEUTICAL COMPOUNDS - The invention provides a compound of the formula (1): | 04-28-2011 |
Peter Williams, Cambridge GB
Patent application number | Description | Published |
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20120194366 | MULTI-BIT DIGITAL TO ANALOGUE CONVERTER AND A DELTA-SIGMA ANALOGUE TO DIGITAL CONVERTER - The present invention relates to a multi-bit digital to analogue converter (DAC) and to a delta-sigma analogue to digital converter employing such a DAC. The DAC has a multi-bit input, a plurality of elements for processing an input signal received at the input and a selector for selecting, based on the input signal, one or more of the DAC elements to process the signal. The DAC has control means for controlling the selector such that if the input to the DAC is below a predetermined level for a predetermined period of time the selector is operative to select only a single one of the DAC elements to process the input signal. Also disclosed is a delta-sigma analogue to digital converter (ADC) employing such a DAC. | 08-02-2012 |
20130223635 | LOW POWER AUDIO DETECTION - Devices and methods of detecting a predetermined audio signal in audio signals are provided. A device includes a processor coupled to a clock signal generator, a power controller and an audio detector. The power controller controls a clock rate provided to the processor by the clock signal generator, to control the device to operate in a low power mode having a relatively low power consumption or in a normal power mode having a relatively high power consumption. The audio detector receives audio signals and detects, in the low power mode, probable presence of a predetermined audio signal in the audio signals. The power controller controls the device to switch from the low power mode to the normal power mode responsive to the detected presence of the predetermined audio signal by the audio detector. | 08-29-2013 |
Peter Andrew Rees Williams, Cambridge GB
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20140192692 | Power Saving for a Communication Device - A communication device comprising: a first radio capable of communicating according to a first protocol and having a set of operational modes; and a second radio capable of communicating according to a second protocol, the communication device being configured to, in dependence on one or more communications by the second radio in accordance with the second protocol, selecting one mode of operation for the first radio from the set of operational modes, wherein said one or more communications comprises: sending a first message; and a response or non-response to the first message. | 07-10-2014 |
20150154486 | PROTECTION OF AN NFC OR RFID RADIO IN THE PRESENCE OF STRONG ELECTROMAGNETIC FIELDS - Methods and devices are described, including a near-field communications (NFC) or radio frequency identification (RFID) device comprising an NFC or RFID circuit, an antenna having at least a first terminal, a first rectifier connected to the first terminal of the antenna, a switch between the first rectifier and the NFC or RFID circuit, a voltage detector for detecting a voltage in the device caused by a signal received at the antenna, and a control module for controlling the switch, wherein when the voltage exceeds a threshold magnitude, the control module controls the switch to be in an open state and, after a predetermined time period, determines whether the voltage still exceeds the threshold magnitude and, if the voltage still exceeds the predetermined magnitude, controls the switch to be in the open state. | 06-04-2015 |
20150188407 | VOLTAGE REGULATOR - A method of operating a voltage regulator including a source voltage rail and a plurality of output voltage rails, the method including: converting a source voltage on the source voltage rail to a respective output voltage on each output voltage rail; selecting an output voltage rail; comparing the output voltage on the selected output voltage rail to a reference voltage for the selected output voltage rail; and if the output voltage of the selected output voltage rail is less than the reference voltage for the selected output voltage rail, controlling the voltage regulator to increase the output voltage on the selected output voltage rail, wherein the frequency at which an output voltage rail is selected is dependent upon the rate at which the voltage regulator has previously increased the output voltage on that output voltage rail. | 07-02-2015 |
20150188517 | CHIP PADS - An integrated circuit having an external connection pad and an active circuit for generating signals to be output from the integrated circuit by means of the pad, the integrated circuit including an interface circuit associated with the pad, the interface circuit including a latch coupled between the pad and an output of the active circuit, the latch being capable of operating in a first mode in which the state of the pad follows the state of the output of the active circuit and a second mode in which the state of the pad is held by the latch. | 07-02-2015 |
T. Haydn Williams, Cambridge GB
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20090255023 | SURGICAL AND MEDICAL GARMENTS AND MATERIALS INCORPORATING SHEAR THICKENING FLUIDS - A surgical garment in the form of a surgical gown, a surgical glove or a surgical mask incorporates a shear thickening fluid as a layer on at least one of the inner and outer surface of the garment, the viscosity of which shear thickening fluid increases to inhibit penetration of the garment. | 10-15-2009 |
Tyler Williams, Cambridge, MA US
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20130262471 | REAL TIME MAPPING OF USER MODELS TO AN INVERTED DATA INDEX FOR RETRIEVAL, FILTERING AND RECOMMENDATION - A catalog record is bridged to information stored in at least one inverted index by receiving an application user interface call associated with a predetermined filter request including a record identifier identifying a record in a relational database. A bitset is generated based on item identifiers in the record. The bitset is applied to at least one inverted index to obtain metadata associated with the item identifiers. | 10-03-2013 |