Jose M.
Jose M. Alandy, Camarillo, CA US
Patent application number | Description | Published |
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20100012786 | GIMBALED, ARTICULATED AND SLIDING SINGLE AND DUAL WALL PRESSURE BALANCED TRANSFER TUBES - The present invention provides an apparatus and method for connecting two sub-flow systems (e.g. airplane fuel tanks) and conveying a fluid between the two sub-systems using a pressured balanced transfer tube, particularly when there are large radial and axial movements or offsets between the sub-systems. Unlike conventional fluid transfer systems, the present apparatus and method allow for the pressure in the transfer tube to be balanced to internalize the pressure forces and prevent the exertion of pressure forces on the sub-systems connected to the transfer tube. | 01-21-2010 |
20120090696 | BREAKAWAY THREAD-LOCK QUICK CONNECT/DISCONNECT COUPLING - A female coupler for a breakaway thread-lock quick disconnect coupling having a retainer wire positioned interiorly of an outer housing and a coupler support portion that prevents contamination of the retainer wire and a capture space formed by grooves in the outer housing and an inner housing, which may prevent degradation of performance and/or decrease the chances that the retainer wire is dislodged. | 04-19-2012 |
Jose M. Aurrecoechea, San Diego, CA US
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20130213045 | Coated Porous Metallic Mat - A porous metallic mat is provided. The porous metallic mat includes a plurality of fibers and a protective coating. The plurality of fibers is sintered into a mat configuration. The protective coating is provided on the porous metallic mat. The protective coating includes a diffusion aluminide configured to provide oxidation resistance to the porous metallic mat. | 08-22-2013 |
Jose M. Borrega, Boston, MA US
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20130298963 | LATERAL PHOTOVOLTAIC DEVICE FOR NEAR FIELD USE - A device, method and process of fabricating an interdigitated multicell thermo-photo-voltaic component that is particularly efficient for generating electrical energy from photons in the red and near-infrared spectrum received from a heat source in the near field. Where the absorbing region is germanium, the device is capable of generating electrical energy by absorbing photon energy in the greater than 0.67 electron volt range corresponding to radiation in the infrared and near-infrared spectrum. Use of germanium semiconductor material provides a good match for converting energy from a low temperature heat source. The side that is opposite the photon receiving side of the device includes metal interconnections and dielectric material which provide an excellent back surface reflector for recycling below band photons back to the emitter. Multiple cells may be fabricated and interconnected as a monolithic large scale array for improved performance. | 11-14-2013 |
Jose M. Bouza, Ii, Bumpass, VA US
Patent application number | Description | Published |
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20080317265 | ANTI-EAVESDROPPING DEVICE - An anti-eavesdropping device is described. The device comprises a receiving compartment for receiving an electronic device, a noise generator, and an EMI filter. The receiving compartment is sealable to minimize signal emissions from the interior to the exterior and from the exterior to the interior, and the noise generator is coupled with the receiving compartment and the EMI filter. The EMI filter is operatively coupled with the noise generator. | 12-25-2008 |
20130077799 | ANTI-EAVESDROPPING DEVICE - An anti-eavesdropping device is described. The device comprises a receiving compartment for receiving an electronic device, a noise generator, and an EMI filter. The receiving compartment is sealable to minimize signal emissions from the interior to the exterior and from the exterior to the interior, and the noise generator is coupled with the receiving compartment and the EMI filter. The EMI filter is operatively coupled with the noise generator. | 03-28-2013 |
Jose M. Bruno-Barcena, Raleigh, NC US
Patent application number | Description | Published |
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20090042236 | Method of identifying hydrogen evolving diazotrophic bacteria - MohC is required for expression of uptake hydrogenase in | 02-12-2009 |
20150307856 | BETA-HEXOSYL-TRANSFERASES AND USES THEREOF - This invention relates generally to the discovery of novel recombinant forms of β-hexosyl-transferases (BHT) and uses thereof to produce galacto-ligosaccharides (GOS) or as food additives. | 10-29-2015 |
Jose M. Capilla, Tournefeuille FR
Patent application number | Description | Published |
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20080315853 | Dc-Dc Converter Controller Having Optimized Load Transient Response and Method Thereof - A power supply controller ( | 12-25-2008 |
20090261794 | DC-DC CONVERTER CONTROLLER HAVING OPTIMIZED LOAD TRANSIENT RESPONSE AND METHOD - A power supply controller ( | 10-22-2009 |
20110012578 | DC-DC CONVERTER CONTROLLER HAVING OPTIMIZED LOAD TRANSIENT RESPONSE - In one embodiment, a power supply controller is configured to turn off a first output transistor but inhibit turning off a second output transistor. | 01-20-2011 |
20140085947 | OFF-LINE POWER CONVERTER AND INTEGRATED CIRCUIT SUITABLE FOR USE IN SAME - An off-line power converter includes an integrated circuit power factor controller including a multi-function input terminal, a drive terminal for providing a drive signal to a gate of a drive transistor, a processing circuit coupled to the multi-function input terminal and, based on a signal received from the multi-function input terminal, providing at least one current signal representative of a current conducted in the off-line power converter, and at least one voltage signal representative of a voltage provided to a load, and a controller for providing the drive signal selectively in response to the at least one current signal and the at least one voltage signal. | 03-27-2014 |
Jose M. Carballido Herrera, Allschwil CH
Patent application number | Description | Published |
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20140099708 | Anti-IL12Rbeta1 Antibodies And Their Use In Treating Autoimmune And Inflammatory Disorders - The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of both the heterodimeric IL12 and IL23 receptors. The invention more specifically relates to specific antibodies that are IL12 and IL23 receptor antagonists capable of inhibiting IL12/IL18 induced IFNγ production of blood cells and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by inhibiting IFNγ production, IL12 and/IL23 signaling, such as rheumatoid arthritis, psoriasis or inflammatory bowel diseases or other autoimmune and inflammatory disorders. | 04-10-2014 |
20140120101 | Anti-IL12Rbeta1 Antibodies And Their Use In Treating Autoimmune And Inflammatory Disorders - The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of both the heterodimeric IL12 and IL23 receptors. The invention more specifically relates to specific antibodies that are IL12 and IL23 receptor antagonists capable of inhibiting IL12/IL18 induced IFNγ production of blood cells and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by inhibiting IFNγ production, IL12 and/IL23 signaling, such as rheumatoid arthritis, psoriasis or inflammatory bowel diseases or other autoimmune and inflammatory disorders. | 05-01-2014 |
20140248265 | THERAPEUTIC ANTIBODIES BINDING IL 12RBETA1 - The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of the heterodimeric IL12 receptor (together with IL12Rβ2 chain) as well as IL23 receptor (together with IL23Rα chain). The invention more specifically relates to specific antibodies that are IL12 and IL23 receptor antagonists capable of inhibiting IL12/IL18 induced IFNy production of T cells and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by inhibiting IFNy production, such as rheumatoid arthritis, psoriasis or inflammatory bowel diseases or other autoimmune and inflammatory disorders. | 09-04-2014 |
Jose M. Castro-Perez US
Patent application number | Description | Published |
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20150320724 | METHODS OF TREATING DIABETES BY ADMINISTERING A GLUCAGON RECEPTOR ANTAGONIST IN COMBINATION WITH A CHOLESTEROL ABSORPTION INHIBITOR - Use of a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor for the treatment of diabetes and related conditions is disclosed. | 11-12-2015 |
Jose M. Castro-Perez, Medford, MA US
Patent application number | Description | Published |
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20090302210 | MASS SPECTROMETER - A mass spectrometer comprising a collision, fragmentation or reaction cell ( | 12-10-2009 |
20110095176 | Mass Spectrometer - A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound. | 04-28-2011 |
Jose M. Castro-Perez, New Providence, NJ US
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20120112055 | Mass Spectrometer - A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound. | 05-10-2012 |
20150320724 | METHODS OF TREATING DIABETES BY ADMINISTERING A GLUCAGON RECEPTOR ANTAGONIST IN COMBINATION WITH A CHOLESTEROL ABSORPTION INHIBITOR - Use of a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor for the treatment of diabetes and related conditions is disclosed. | 11-12-2015 |
Jose M. Cerdas, Galveston, TX US
Patent application number | Description | Published |
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20150197323 | WEARABLE AND BUOYANT LIFE SAVING APPARATUSES - A wearable life saving apparatus may have or include at least one inflatable raft attached to at least one tethering material for securing the inflatable raft(s) to a user's body. The tethering material may be a cord, a string, a strap, or some other mechanism allowing the wearable life saving apparatus to be worn by a user. The inflatable raft may have a compressed gas unit mounted inside, inboard, or on each inflatable raft. The compressed gas unit may have a release mechanism that is releasable exterior to the at least one inflatable buoyancy body. | 07-16-2015 |
Jose M. Corcelles Pereira, Madrid ES
Patent application number | Description | Published |
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20100084865 | STATOR CONTROLLED INDUCTION GENERATORS WITH SHORT-CIRCUITED ROTOR - A generator is connectable to a turbine for generating electric power or a motor. An electric power generator system or a motor comprises an asynchronous short-circuited rotor generator or motor comprising a stator, a rotor, and a transformer having a first winding and a second winding, the first winding having a first end and a second end. The stator and the transformer are connectable in series with an electric power distribution grid. | 04-08-2010 |
20110018270 | DOUBLY-CONTROLLED ASYNCHRONOUS GENERATOR - An electric power generator system or a motor comprising a doubly-fed asynchronous generator or motor comprising a stator and a rotor; a transformer having a first winding and a second winding, the first winding having a first end and a second end; and wherein the stator and the transformer are connectable in series with an electric power distribution grid. | 01-27-2011 |
Jose M. Cruz-Albrecht, Oak Park, CA US
Patent application number | Description | Published |
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20110200225 | ADVANCED BACKGROUND ESTIMATION TECHNIQUE AND CIRCUIT FOR A HYPER-SPECTRAL TARGET DETECTION METHOD - A system, circuit and methods for target detection from hyper-spectral image data are disclosed. Filter coefficients are determined using a modified constrained energy minimization (CEM) method. The modified CEM method can operate on a circuit operable to perform constrained linear programming optimization. A filter comprising the filter coefficients is applied to a plurality of pixels of the hyper-spectral image data to form CEM values for the pixels, and one or more target pixels are identified from the CEM values. The process may be repeated to enhance target recognition by using filter coefficients determined by excluding the identified target pixels from the hyper-spectral image data. | 08-18-2011 |
Jose M. Eirin, Toronto CA
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20140210178 | Multi-Use Vehicle Assembly - A multi-use vehicle assembly provides a means for entertainment and mobilization. The vehicle assembly includes a frame assembly having a first frame coupled to a second frame. The frame assembly has a center frame coupled to and extending between the first frame and the second frame. A plurality of wheels is coupled to the frame assembly. The plurality of wheels comprises a left back wheel, a right back wheel, and a central front wheel. The left back wheel is coupled to the first frame. The right back wheel is coupled to the second frame. The central front wheel is coupled to the center frame. A steering mechanism is coupled to the frame assembly. The steering mechanism is mechanically coupled to the central front wheel. A drive system is operationally coupled to one of the plurality of wheels. | 07-31-2014 |
Jose M. Fernandes Portocarrero, Macieira Da Maia PT
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20140014668 | HYBRID PRESSURE VESSELS FOR HIGH PRESSURE APPLICATIONS - A pressure vessel is provided including an inner tank formed from a tank liner surrounded by a wound layer of composite filaments. A protective jacket is disposed on the inner tank that facilitates stacking and portability of the pressure vessel and helps to define an air passage for convective heat transfer between the hybrid tank and the environment. | 01-16-2014 |
Jose M. Fernandeze Martinez, Cordoba ES
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20090138993 | Sunflower seeds with high delta-tocopherol content - The present invention relates to sunflower seeds which have been genetically modified through two artificial induction cycles of mutations followed in each case by processes for the identification of mutant individuals which have the desired character. The disclosed seeds are characterised in that they contain between 26% and 80% of the tocopherols as delta-tocopherol. This high delta-tocopherol production is determined by the genotype of the seeds which have been modified to this effect, and is always obtained independently of the culture conditions, thereby obtaining an inheritable character. Today, sunflower seeds producing such high levels of delta-tocopherol do not exist. Genetically modified sunflower plants which produce through self-fertilisation seeds with high delta-tocopherol levels and the oil with high natural delta-tocopherol concentration, extracted from the seeds, are also objectives of the present invention. | 05-28-2009 |
Jose M. Fiandor, Madrid ES
Patent application number | Description | Published |
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20090054379 | 7-Pyrollyl 9-Aminoacyl Tetracycline Compounds and Methods of Use Thereof - A compound of formula (I): | 02-26-2009 |
20100075929 | 9-AMINOACYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF - A compound of formula (I): | 03-25-2010 |
20100081826 | 7-PYRROLYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF - A compound of Formula (I): | 04-01-2010 |
20110160165 | 7-Pyrazolyl Tetracycline Compounds and Methods of Use Thereof - The present invention provides compounds of Formula (I) and related methods and formulations: | 06-30-2011 |
Jose M. Furtado, Campinas BR
Patent application number | Description | Published |
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20110093680 | FLEXIBLE MEMORY CONTROLLER FOR AUTONOMOUS MAPPING OF MEMORY - A memory controller implements flexible memory mapping for storage of data units in a memory. The memory controller logically partitions the memory into a plurality of blocks or block segments and manages the storage of data units among the plurality of blocks/block segments. The memory controller can operate in one of three modes: a monolithic mode whereby the memory is modeled as a plurality of blocks, whereby each block is treated as a “monolithic” block; a fragmented mode whereby the memory is modeled as a plurality of blocks segments of varying sizes; and a combined mode whereby the memory is initially partitioned into a plurality of equal-sized blocks, and whereby each block can be used as a monolithic block or a fragmented block comprising a plurality of block segments of different sizes, and wherein monolithic blocks can be converted to fragmented blocks and fragmented blocks can be converted back to monolithic blocks. | 04-21-2011 |
Jose M. Galmes, San Diego, CA US
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20120313778 | CONTROLLING PRINTING OF A DOCUMENT THAT MAY CONTAIN MICR CHARACTERS - A technique includes in a machine, processing data indicative of a document to be printed by a printer and which may contain magnetic ink character recognition (MICR) characters to determine whether the data indicates any MICR characters. The technique includes comparing a result of the determination to an intent indicated by a job ticket associated with the document; and controlling the printing of the document by the printer, including selectively performing corrective action in response to the comparison. | 12-13-2012 |
20120313988 | APPLYING BONDING AGENT FOR SUPPLEMENTAL INK - A method for applying a bonding agent for supplemental ink includes, with a control system of a printing apparatus, determining regions of an image corresponding to regions where a supplemental ink is to be printed, and with the control system, adding an amount of pixels of a standard color channel to portions of a bitmap representing the image, the portions corresponding to the regions where the supplemental ink is to be printed. The amount of pixels is sufficient to trigger application of a bonding agent at the regions. | 12-13-2012 |
20140111818 | Data Flow to a Printing Device - A method of increasing data flow to a printing device includes, with a first raster image processor, converting a document into a first bitmap having a first dot density and representing a black color plane of the document; with a second raster image processor, converting the document into a second bitmap at a second dot density that is a relatively lower dot density than that of the first bitmap, the second bitmap representing other color planes of the document; and transmitting data of the first and second bitmaps to a printing device for printing to a print medium. | 04-24-2014 |
20140355042 | Printing System - An example method for operating a printing system in accordance with aspects of the present disclosure includes receiving, at a printing unit, a print job, receiving, at the printing unit, a trigger generated by a finishing unit, and initiating the print job based on the generated trigger. | 12-04-2014 |
Jose M. Hernandez, Jr., Miramar, FL US
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20100217159 | GAIT SYMMETRY MEASUREMENT AND IMPROVEMENT - A gait-enhancing system and method of enhancing gait includes generating a reference signal having substantially equal durations between occurrences and providing the reference signal to a user. Contact between the feet of the user with a surface is received and occurrence of a trigger signal is generated in response to the contact. An occurrence of the trigger signal is compared with an occurrence of a reference signal, and a guidance signal is produced as a function of the amount of time that the trigger signal led or lagged the reference signal. The guidance signal is provided to the user in order to promote symmetry in stride between one foot and the other foot of the user, enhancing the user's gait. | 08-26-2010 |
20150133825 | METHOD OF ENHANCING GAIT OF A USER - A gait-enhancing system and method of enhancing gait includes generating a reference signal having substantially equal durations between occurrences and providing the reference signal to a user. Contact between the feet of the user with a surface is received and occurrence of a trigger signal is generated in response to the contact. An occurrence of the trigger signal is compared with an occurrence of a reference signal, and a guidance signal is produced as a function of the amount of time that the trigger signal led or lagged the reference signal. The guidance signal is provided to the user in order to promote symmetry in stride between one foot and the other foot of the user, enhancing the user's gait. | 05-14-2015 |
Jose M. Herrera, Jr., Laredo, TX US
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20140305983 | HANGER BRACKET FOR TRANSFORMING AND CONCEALING EXISTING GUN HOLSTERS - A hanger bracket is attached to any existing gun holster with the existing holster belt clip removed from the holster and attached to a top of the bracket. The bottom of the bracket is attached to the holster at the previous attachment location of the belt clip to the holster. The belt clip is attached over the outside of a belt of a user and the bracket, holster and gun are inserted down inside the pants of the user for complete concealment. The shape, spacing, orientation, and number of holster attachment openings through the bracket make it adaptable to a variety of holsters and adjustable to various vertical heights of the holster attachment to the bracket. | 10-16-2014 |
Jose M. Lazaro Bolos, Madrid ES
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20120178092 | Method for the Replication, Amplification or Sequencing of a DNA Template - Methods for replicating, amplifying or sequencing a deoxyribonucleic acid with a φ29 type DNA polymerase are disclosed, along with kits for carrying out the methods. | 07-12-2012 |
20120190014 | PHAGE PHI 29 DNA POLYMERASE CHIMERA - A DNA polymerase chimera comprising an amino-terminal (N-terminal) region encoding a φ29 type DNA polymerase and a carboxyl-terminal (C-terminal) region comprising at least one HhH domain which are bound by means of a connecting amino acid sequence is disclosed along with and the use thereof for replicating, amplifying or sequencing a template DNA. Also disclosed is a method for replicating, amplifying or sequencing a deoxyribonucleic acid with said DNA polymerase chimera and kits for carrying out said methods. | 07-26-2012 |
20130236886 | Phage Phi 29 DNA Polymerase Chimera - A DNA polymerase chimera comprising an amino-terminal (N-terminal) region encoding a φ29 type DNA polymerase and a carboxyl-terminal (C-terminal) region comprising at least one HhH domain which are bound by a connecting amino acid sequence is disclosed along with and the use thereof for replicating, amplifying or sequencing a template DNA. Also disclosed is a method for replicating, amplifying or sequencing a deoxyribonucleic acid with a DNA polymerase chimera and kits for carrying out the methods. | 09-12-2013 |
20140178939 | METHOD FOR DNA AMPLIFICATION BASED ON THE ORIGINS OF REPLICATION OF THE BACTERIOPHAGE P29 AND ASSOCIATED NUCLEOTIDE SEQUENCES - The present invention refers to a DNA amplification method based on the origins of replication of bacteriophage φ29, and to the genic constructs, vectors and oligonucleotides that can be used in the method for amplifying an exogenous sequence of interest. | 06-26-2014 |
Jose M. Lobez, Boston, MA US
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20110081724 | METHOD AND APPARATUS FOR DETERMINING RADIATION - The present invention relates to devices, systems, and methods for determination of ionizing radiation. In some embodiments, the devices comprise nanocomposite materials containing nanostructures (e.g., carbon nanotubes) dispersed in radiation sensitive polymers. In some cases, the device may include a conductive pathway that may be affected upon exposure to ionizing radiation. Embodiments described herein may provide inexpensive, large area, low power, and highly sensitive radiation detection materials/devices. | 04-07-2011 |
20120073662 | COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING POLY(THIOPHENES) - The present invention generally relates to compositions comprising at least one poly(thiophene) and an n-type material. The compositions can be used in a variety of applications, for example, in photovoltaic cells. | 03-29-2012 |
20120295360 | METHOD AND APPARATUS FOR DETERMINING RADIATION - The present invention relates to devices, systems, and methods for determination of ionizing radiation. In some embodiments, the devices comprise nanocomposite materials containing nanostructures (e.g., carbon nanotubes) dispersed in radiation sensitive polymers. In some cases, the device may include a conductive pathway that may be affected upon exposure to ionizing radiation. Embodiments described herein may provide inexpensive, large area, low power, and highly sensitive radiation detection materials/devices. | 11-22-2012 |
Jose M. Lobez Comeras, New York, NY US
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20140363638 | Surface Modification Using Functional Carbon Nanotubes - Techniques for CNT solubilization and surface-selective deposition via polymer-mediated assembly are provided. In one aspect, a method for self-assembly of CNTs on a substrate is provided. The method includes the following steps. One or more surfaces of the substrate are coated with a thiol-reactive compound. The substrate is contacted with carbon nanotube-polymer assemblies dispersed in a solvent, wherein the carbon nanotube-polymer assemblies include the carbon nanotubes wrapped in a polymer having side chains with thiol groups. Wherein by way of the step of contacting the substrate with the carbon nanotube-polymer assemblies, the carbon nanotube-polymer assemblies selectively bind to the surfaces of the substrate based on an interaction between the thiol groups in the polymer and the thiol-reactive compound on the surfaces of the substrate and thereby self-assemble on the substrate. | 12-11-2014 |
20140363641 | Surface Modification Using Functional Carbon Nanotubes - Techniques for CNT solubilization and surface-selective deposition via polymer-mediated assembly are provided. In one aspect, a method for self-assembly of CNTs on a substrate is provided. The method includes the following steps. One or more surfaces of the substrate are coated with a thiol-reactive compound. The substrate is contacted with carbon nanotube-polymer assemblies dispersed in a solvent, wherein the carbon nanotube-polymer assemblies include the carbon nanotubes wrapped in a polymer having side chains with thiol groups. Wherein by way of the step of contacting the substrate with the carbon nanotube-polymer assemblies, the carbon nanotube-polymer assemblies selectively bind to the surfaces of the substrate based on an interaction between the thiol groups in the polymer and the thiol-reactive compound on the surfaces of the substrate and thereby self-assemble on the substrate. | 12-11-2014 |
20140363643 | Surface-Selective Carbon Nanotube Deposition Via Polymer-Mediated Assembly - Techniques for carbon nanotube (CNT) solubilization and surface-selective deposition via polymer-mediated assembly are provided. In one aspect, a method for self-assembly of carbon nanotubes on a substrate is provided. The method includes the following steps. A charge is created on one or more surfaces of the substrate. The substrate is contacted with carbon nanotube-polymer assemblies dispersed in a solvent, wherein the carbon nanotube-polymer assemblies include the carbon nanotubes wrapped in a polymer having side chains with charged functional groups, and wherein by way of the contacting step the carbon nanotube-polymer assemblies selectively bind to the charged surfaces of the substrate based on complementary electrostatic interactions between the charged functional groups on the polymer and the charged surfaces of the substrate and thereby self-assemble on the substrate. A resulting structure is also provided. | 12-11-2014 |
20140364574 | Surface-Selective Carbon Nanotube Deposition via Polymer-Mediated Assembly - Techniques for carbon nanotube (CNT) solubilization and surface-selective deposition via polymer-mediated assembly are provided. In one aspect, a method for self-assembly of carbon nanotubes on a substrate is provided. The method includes the following steps. A charge is created on one or more surfaces of the substrate. The substrate is contacted with carbon nanotube-polymer assemblies dispersed in a solvent, wherein the carbon nanotube-polymer assemblies include the carbon nanotubes wrapped in a polymer having side chains with charged functional groups, and wherein by way of the contacting step the carbon nanotube-polymer assemblies selectively bind to the charged surfaces of the substrate based on complementary electrostatic interactions between the charged functional groups on the polymer and the charged surfaces of the substrate and thereby self-assemble on the substrate. A resulting structure is also provided. | 12-11-2014 |
20150034834 | Radiation Detector Based on Charged Self-Assembled Monolayers on Nanowire Devices - Radiation detectors having nanowires with charged, radiation-labile coatings configured to change the electrical properties of nanowires are provided. In one aspect, a radiation detection device is provided. The radiation detector device includes at least one nanowire having a radiation-labile coating with charged moieties on a surface thereof, wherein the radiation-labile coating is configured to degrade upon exposure to radiation such that the charged moieties are cleaved from the radiation-labile coating upon exposure to radiation and thereby affect a transconductance of the nanowire. | 02-05-2015 |
20150037895 | Hydrocarbon Detector Based on Carbon Nanotubes - Hydrocarbon detectors having CNTs coated with an amphiphilic coating capable of sequestering an active molecule are provided. In one aspect, a hydrocarbon detection device is provided. The hydrocarbon detector device includes a plurality of CNTs dispersed in a polar solvent, wherein each of the CNTs is coated with an amphiphilic coating having molecules with a hydrophilic moiety and a hydrophobic moiety, and wherein the coating creates a hydrophobic environment proximal to a surface of each of the CNTs; and one or more hydrophobic active molecules sequestered in the hydrophobic environment proximal to the surface of each of the CNTs. | 02-05-2015 |
20150104352 | USE OF DISULFIDE BONDS TO FORM A REVERSIBLE AND REUSABLE COATING FOR NANOFLUIDIC DEVICES - A reusable coating for a nanopore structure is disclosed herein. A nanopore structure includes a substrate comprising a nanochannel and a monolayer of a chemical compound disposed onto at least a portion of a surface of the nanochannel. The chemical compound forms a reversible bond with at least one analyte binding compound introduced into the nanochannel. Methods for making and using the reusable coating are also disclosed. | 04-16-2015 |
20150104877 | USE OF DISULFIDE BONDS TO FORM A REVERSIBLE AND REUSABLE COATING FOR NANOFLUIDIC DEVICES - A reusable coating for a nanopore structure is disclosed herein. A nanopore structure includes a substrate comprising a nanochannel and a monolayer of a chemical compound disposed onto at least a portion of a surface of the nanochannel. The chemical compound forms a reversible bond with at least one analyte binding compound introduced into the nanochannel. Methods for making and using the reusable coating are also disclosed. | 04-16-2015 |
Jose M. Lora, London GB
Jose M. Moita, Edmonton CA
Patent application number | Description | Published |
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20150282434 | CURB FOR LANDSCAPING - There is provided a curb for landscaping having a base portion, a cover portion, a curb front end and a curb rear end. The base portion has a top surface and a flat bottom surface. The cover portion has an outer surface and an inner surface. The base portion and the cover portion have front and rear edges, and these front edges are attached to define the curb front end. The cover portion overlies and extends above the base portion such that the rear edges are spaced apart. The curb rear end has one or more drainage openings above the top surface of the base portion, and the curb front end has one or more drainage outlets adjacent to and above the front edge of the base portion, the drainage outlets being in fluid communication with the drainage openings and permitting water to drain through the curb body. | 10-08-2015 |
Jose M. Molineros, Encino, CA US
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20120328203 | Image Registration - A method and apparatus for processing images. Clusters of first features identified in a first image are identified. Each cluster in the clusters comprises a first group of features from the first features. A transformation for registering each cluster in the clusters with a corresponding cluster comprising a second group of features from second features identified in a second image is identified using an initial correspondence between the first features in the first image and the second features in the second image. A set of clusters from the clusters of the first features is identified using the transformation identified for each cluster. A final transformation for registering the first image with the second image is identified using the set of clusters. | 12-27-2012 |
20130004017 | Context-Based Target Recognition - A method and apparatus for identifying a target object. A group of objects is identified in an image. The group of objects provides a context for identifying the target object in the image. The target object is searched for in the image using the context provided by the group of objects. | 01-03-2013 |
Jose M. Mora-Gutierrez, Sevilla ES
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20120057721 | COMPONENT HAVING A MICROMECHANICAL MICROPHONE STRUCTURE, AND METHOD FOR OPERATING SUCH A MICROPHONE COMPONENT - A concept is proposed for a MEMS microphone which may be operated at a relatively low voltage level and still have comparatively high sensitivity. The component according to the present invention includes a micromechanical microphone structure having an acoustically active diaphragm which functions as a deflectable electrode of a microphone capacitor ( | 03-08-2012 |
Jose M. Moran-Mirabal, Ithaca, NY US
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20090072728 | ELECTROSPUN LIGHT-EMITTING FIBERS - The invention teaches electrospun light-emitting fibers made from ionic transition metal complexes (“iTMCs”) such as [Ru(bpy) | 03-19-2009 |
20120097832 | ELECTROSPUN LIGHT-EMITTING FIBERS - The invention teaches electrospun light-emitting fibers made from ionic transition metal complexes (‘iTMCs”) such as [Ru(bpy) | 04-26-2012 |
Jose M. Ordovas, Framingham, MA US
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20080275728 | Method for Personalized Diet Design for Females of Asian Origin - The present invention provides methods for personalized diet design for females of Asian origin, wherein females who are homozygous for the PLIN 11482A are advised to avoid diets high in fat and low in carbohydrates, to avoid or manage metabolic syndrome and conditions related to metabolic syndrome, such as insulin resistance, diabetes, and cardiovascular disease. | 11-06-2008 |
20090222282 | Method for Personalized Diet Design - The present invention is directed to methods of developing dietary guidelines, particularly associated with dietary consumption of fatty acids. We discovered an association of a polymorphic marker with regulation of plasma lipid levels in response to dietary intake of polyunsaturated fatty acids. Accordingly, the present invention provides methods for providing individualized guidance in design of dietary interventions to alter plasma lipid profiles by genotyping APOA5 locus, wherein the presence of APOA5−1131C, APOA5−3G, APOA5 IVS3+476A, and APOA5 1259C alleles or alleles that are found to be in tight linkage disequilibrium with APOA5−1131C, APOA5−3G, APOA5 IVS3+476A, and APOA5 1259C alleles, is indicative of the individual being susceptible to altered plasma lipid levels in response to intake of n-6 polyunsaturated fatty acids. | 09-03-2009 |
20100184081 | GENETIC MARKERS FOR OBESITY - The present invention is directed to new genetic variants or polymorphisms at the perilipin locus (PLIN) including PLIN1: 6209T (allele 1)>C (allele 2); PLIN3 10171 (allele 1) A >T (allele 2); PLIN4: 11482G (allele 1)>A (allele 2); PLIN5: 13041A (allele 1)>G (allele 2) and PLIN6: 14995A (allele 1)>T (allele 2), and their use in diagnostic and prognostic applications for obesity and obesity-related diseases, such as metabolic syndrome and cardiovascular disease. | 07-22-2010 |
Jose M. Orro, Cary, NC US
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20100250981 | DYNAMIC MEMORY VOLTAGE SCALING FOR POWER MANAGEMENT - In the context of computer systems, the present invention broadly contemplates the ability to dynamically adjust the voltage and frequency of DRAM memory modules that are dual-voltage tolerant based on system performance. The invention allows a computer system to dynamically scale the memory voltage between a lower and a higher voltage, thereby allowing the system to save power when the system is idle or in low usage, but also allowing the system to realize the full memory performance when running more intensive applications. | 09-30-2010 |
Jose M. Revuelta, Cantabria ES
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20140052242 | REPLACEMENT PROSTHETIC HEART VALVE, SYSTEM AND METHOD OF IMPLANT - A prosthetic heart valve for functionally replacing a previously implanted prosthetic heart valve is disclosed. The prosthetic heart valve includes a collapsible support structure with leaflets and anchors mounted to the support structure. The support structure also includes an inflow end and an outflow end. The anchors include a radially outwardly extending first anchor proximate to the inflow end and a radially outwardly extending second anchor proximate to the outflow end. The first anchor includes a first configuration and the second anchor includes a second configuration where the first configuration is different than the second configuration. The previously implanted prosthetic heart valve serves as a platform for securement of the prosthetic heart valve to the patient's native tissue. | 02-20-2014 |
Jose M. San Juan, Bilbao ES
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20100140439 | Superelastic Alloy Structural Geometry for Ultrahigh Mechanical Damping - A mechanical structure is provided with a crystalline superelastic alloy that is characterized by an average grain size and that is characterized by a martensitic phase transformation resulting from a mechanical stress input greater than a characteristic first critical stress. A configuration of the superelastic alloy is provided with a geometric structural feature of the alloy that has an extent that is no greater than about 200 micrometers and that is no larger than the average grain size of the alloy. This geometric feature is configured to accept a mechanical stress input. | 06-10-2010 |
20140326849 | Superelastic Alloy Structural Geometry for Ultrahigh Mechanical Damping - A mechanical structure is provided with a crystalline superelastic alloy that is characterized by an average grain size and that exhibits a martensitic phase transformation resulting from a mechanical stress input greater than a characteristic first critical stress. A configuration of the superelastic alloy is provided with a geometric structural feature of the alloy that has an extent that is no greater than about 200 micrometers and that is no larger than the average grain size of the alloy. This geometric feature undergoes the martensitic transformation without intergranular fracture of the geometric feature. | 11-06-2014 |
Jose M. Soler Pons, Gerona ES
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20110192297 | PRINTING SYSTEM HAVING A RAISED IMAGE PRINTING CYLINDER - A printing arrangement having a rotatable printing cylinder and raised image and non-raised non-image portions on the circumference of the printing cylinder. The arrangement has an array of smooth rollers for applying an ink onto the image on the printing cylinder and not applying ink onto the non-image portion. A first smooth roller is mounted for rotation near the printing cylinder and a second smooth roller mounted for rotation near the first roller forming an ink gap between the two smooth rollers. Ink is dispersed across the first smooth roller and applied onto the image on the printing cylinder. The arrangement has a rotatable counter pressure cylinder mounted with the printing cylinder such that when a web is passed through a gap between the printing and counter pressure cylinders, and when ink applied to the image portion on the printing cylinder, ink is transferred from the image onto the substrate material. | 08-11-2011 |
Jose M. Trevejo, Brighton, MA US
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20090239252 | RAPID DETECTION OF VOLATILE ORGANIC COMPOUNDS FOR IDENTIFICATION OF BACTERIA IN A SAMPLE - In various embodiments, the invention relates to a method for identifying the presence of particular bacteria in a sample. The method includes collecting a sample that includes or has been exposed to the particular bacteria and detecting, in the sample, at least one volatile organic compound indicative of the presence of the bacteria. | 09-24-2009 |
20100291617 | RAPID DETECTION OF VOLATILE ORGANIC COMPOUNDS FOR IDENTIFICATION OF MYCOBACTERIUM TUBERCULOSIS IN A SAMPLE - In various embodiments, the invention relates to a method for identifying the presence of particular bacteria in a sample. The method includes collecting a sample that includes or has been exposed to the particular bacteria and detecting, in the sample, at least one volatile organic compound indicative of the presence of the bacteria. | 11-18-2010 |
Jose M. Vieltes, Madrid ES
Patent application number | Description | Published |
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20120231972 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same - The present invention relates to a probe compound that can comprise any substrate or metabolite of an enzymatic reaction in addition to an indicator component, such as, for example, a fluorescence dye, or the like. Moreover, the present invention relates to means for detecting enzymes in form of an array, which comprises any number of probe compounds of the invention which each comprise a different metabolite of interconnected metabolites representing the central pathways in all forms of life. Moreover, the present invention relates to a method for detecting enzymes involving the application of cell extracts or the like to the array of the invention which leads to reproducible enzymatic reactions with the substrates. These specific enzymatic reactions trigger the indicator (e.g. a fluorescence signal) and bind the enzymes to the respective cognate substrates. Moreover, the invention relates to means for isolating enzymes in form of nanoparticles coated with the probe compound of the invention. The immobilisation of the cognate substrates or metabolites on the surface of nanoparticles by means of the probe compounds allows capturing and isolating the respective enzyme, e.g. for subsequent sequencing. | 09-13-2012 |
Jose M. Zabala Zabala, Asteasu (guipuzcoa) ES
Patent application number | Description | Published |
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20110245031 | BOGIE PLATE FOR WIND TURBINE - Bogie plate ( | 10-06-2011 |
Jose M. Zubeldia, London GB
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20090175783 | COMPOUNDS AND IMAGING METHODS - The present invention relates to methods of distinguishing between active and inactive blood clots in vivo, including assisting in the determination of whether it is appropriate or not to continue anticoagulant therapy for an individual patient with previously diagnosed venous thrombo-embolic disease (VTE). | 07-09-2009 |
José M. Álvarez Pastor, Salamanca ES
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20110253901 | DEVICE FOR DETECTING HIGHLY ENERGETIC PHOTONS | 10-20-2011 |
José M. Asua González, Donostia-San Sebastian-Gipuzkoa ES
Patent application number | Description | Published |
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20120208014 | AQUEOUS HYBRID POLYURETHANE-ACRYLIC ADHESIVES - A process for the preparation of adhesives compositions comprising polymerization of a mixture of acrylic and methacrylic monomers comprising one or more acrylate or methacrylate having active hydrogens in the presence of an isocyanate terminated polyurethane prepolymer and optionally a chain extender. | 08-16-2012 |
José M. Barral, Galveston, TX US
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20090325874 | Inhibition of inositol 1,4,5-triphosphate receptor calcium channel/cytochrome c interactions and uses thereof - The present invention demonstrates selective pharmacological targeting and inhibition of apoptotic calcium release in lymphocytes from inositol 1,4,5-trisphosphate receptor calcium channels may enhance the immunologic response to tumor cells which have acquired adaptive changes in death receptor signaling to promote survival. The present invention provides methods of protecting lymphocytes from tumor cell-induced apoptotic cell death by contacting lymphocytes with one or more cell permeant peptide(s). Also provided are methods of inhibiting caspase activation and blocking calcium release by blocking binding of cytochrome c to the inositol 1,4,5-triphosphate receptor calcium channel. In addition, methods are provided to treat a cancer, enhance immunologic response by administering or applying small molecule inhibitor, e.g., cell permeant peptides specific for the cytochrome c binding domain of inositol 1,4,5-triphosphate receptor calcium channel. | 12-31-2009 |
José M. Barral, Galveston, TX US
Patent application number | Description | Published |
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20090325874 | Inhibition of inositol 1,4,5-triphosphate receptor calcium channel/cytochrome c interactions and uses thereof - The present invention demonstrates selective pharmacological targeting and inhibition of apoptotic calcium release in lymphocytes from inositol 1,4,5-trisphosphate receptor calcium channels may enhance the immunologic response to tumor cells which have acquired adaptive changes in death receptor signaling to promote survival. The present invention provides methods of protecting lymphocytes from tumor cell-induced apoptotic cell death by contacting lymphocytes with one or more cell permeant peptide(s). Also provided are methods of inhibiting caspase activation and blocking calcium release by blocking binding of cytochrome c to the inositol 1,4,5-triphosphate receptor calcium channel. In addition, methods are provided to treat a cancer, enhance immunologic response by administering or applying small molecule inhibitor, e.g., cell permeant peptides specific for the cytochrome c binding domain of inositol 1,4,5-triphosphate receptor calcium channel. | 12-31-2009 |
20130149699 | Translation Kinetic Mapping, Modification and Harmonization - The profile of translation elongation rate along an mRNA is modulated in a directed manner by locally altering codon usage, in particular utilizing differences in ribosomal dwell times among pairs of synonymous codons translated by a single tRNA through wobble base pairing. Unlike codon optimization based on organism-specific codon frequencies or tRNA pools, the methods of the invention need not change the tRNA that translates the codon, rather modulating the interaction between a given tRNA and the mRNA coding sequence. | 06-13-2013 |
José M. Berenguer Prieto, Valencia ES
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20120309872 | BITUMINOUS MATERIAL AND ITS USE FOR THE CONSTRUCTION OF SUB-BALLAST - The present invention relates to a novel bituminous material using vulcanized rubber powder from out-of-use tires, and the use of the same for the construction of sub-ballast. | 12-06-2012 |
José M. Berenguer Prieto, Valencia ES
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20120309872 | BITUMINOUS MATERIAL AND ITS USE FOR THE CONSTRUCTION OF SUB-BALLAST - The present invention relates to a novel bituminous material using vulcanized rubber powder from out-of-use tires, and the use of the same for the construction of sub-ballast. | 12-06-2012 |
José M. Carballido Herrera, Basel CH
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20110076270 | Therapeutic Binding Molecules - A molecule comprising at least one antigen binding site, comprising in sequence the hypervariable regions CDR1, CDR2 and CDR3, said CDR1 having the amino acid sequence Asn-Tyr-Ile-Ile-His (NYIIH), said CDR2 having the amino acid sequence Tyr-Phe-Asn-Pro-Tyr-Asn-His-Gly-Thr-Lys-Tyr-Asn-Glu-Lys-Phe-Lys-Gly (YFNPYNHGTKYNEKFKG) and said CDR3 having the amino acid sequence Ser-Gly-Pro-Tyr-Ala-Trp-Phe-Asp-Thr (SGPYAWFDT); e.g. further comprising in sequence the hypervariable regions CDR1′, CDR2′ and CDR3′, CDR1′ having the amino acid sequence Arg-Ala-Ser-Gln-Asn-Ile-Gly-Thr-Ser-Ile-Gln (RASQNIGTSIQ), CDR2′ having the amino acid sequence Ser-Ser-Ser-Glu-Ser-Ile-Ser (SSSESIS) and CDR3′ having the amino acid sequence Gln-Gln-Ser-Asn-Thr-Trp-Pro-Phe-Thr (QQSNTWPFT), e.g. a chimeric or humanised antibody, useful as a pharmaceutical. | 03-31-2011 |
José M. Carballido Herrera, Allschwil CH
Patent application number | Description | Published |
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20120034231 | COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES - The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of the heterodimeric IL12 receptor (together with IL12Rβ2 chain) as well as IL23 receptor (together with IL23Rα chain). The invention more specifically relates to specific antibodies that are IL12 and IL23 receptor antagonists capable of inhibiting IL12/IL18 induced IFNγ production of T cells and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by inhibiting IFNγ production, such as rheumatoid arthritis, psoriasis or inflammatory bowel diseases or other autoimmune and inflammatory disorders. | 02-09-2012 |
20120082681 | ANTI-IL12RBETA1 ANTIBODIES AND THEIR USE IN TREATING AUTOIMMUNE AND INFLAMMATORY DISORDERS - The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of both the heterodimeric IL12 and IL23 receptors. The invention more specifically relates to specific antibodies that are IL12 and IL23 receptor antagonists capable of inhibiting IL12/1L18 induced IFNγ production of blood cells and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by inhibiting IFNγ production, IL12 and/IL23 signaling, such as rheumatoid arthritis, psoriasis or inflammatory bowel diseases or other autoimmune and inflammatory disorders. | 04-05-2012 |
José M. Carballido Herrera, Basel CH
Patent application number | Description | Published |
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20100183602 | Induction of Tolerogenic Phenotype in Mature Dendritic Cells - The present invention relates to the use of a CD45 binding molecule to modulate the function of Dendritic cells. In particular the present invention relates to the use of a CD45 binding molecule to induce tolerogenic dendritic cells, useful in the treatment of diseases or disorders such as autoimmune diseases, transplant rejection. | 07-22-2010 |
20110076270 | Therapeutic Binding Molecules - A molecule comprising at least one antigen binding site, comprising in sequence the hypervariable regions CDR1, CDR2 and CDR3, said CDR1 having the amino acid sequence Asn-Tyr-Ile-Ile-His (NYIIH), said CDR2 having the amino acid sequence Tyr-Phe-Asn-Pro-Tyr-Asn-His-Gly-Thr-Lys-Tyr-Asn-Glu-Lys-Phe-Lys-Gly (YFNPYNHGTKYNEKFKG) and said CDR3 having the amino acid sequence Ser-Gly-Pro-Tyr-Ala-Trp-Phe-Asp-Thr (SGPYAWFDT); e.g. further comprising in sequence the hypervariable regions CDR1′, CDR2′ and CDR3′, CDR1′ having the amino acid sequence Arg-Ala-Ser-Gln-Asn-Ile-Gly-Thr-Ser-Ile-Gln (RASQNIGTSIQ), CDR2′ having the amino acid sequence Ser-Ser-Ser-Glu-Ser-Ile-Ser (SSSESIS) and CDR3′ having the amino acid sequence Gln-Gln-Ser-Asn-Thr-Trp-Pro-Phe-Thr (QQSNTWPFT), e.g. a chimeric or humanised antibody, useful as a pharmaceutical. | 03-31-2011 |
José M. Carballido Herrera, Vienna AT
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20090208997 | GPR18 as a Biomaker for TH1 Mediated Immune Response - The present invention provides the use of GPR18 in diseases or disorders mediated by Th1 cell activation. | 08-20-2009 |
20090317827 | Receptor In Dendritic Cells - The present invention provides the use of GPR91 as a target in dendritic cells. | 12-24-2009 |
José M. Catala-Civera, Valencia ES
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20080292813 | Microwave Heating Device With Irradiation Arrangement - The invention relates to a heating device ( | 11-27-2008 |
José M. Catala-Civera, Valencia ES
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20080292813 | Microwave Heating Device With Irradiation Arrangement - The invention relates to a heating device ( | 11-27-2008 |
José M. Corral, Quedlinburg DE
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20140096280 | MEANS AND METHODS TO INDUCE APOMIXIS IN PLANTS - The present invention relates to nucleic acid molecules for use in inducing aponnixis in a plant, transgenic cells, in particular transgenic plant cells, comprising said nucleic acid molecule, transgenic plants, in particular plant seeds, comprising said nucleic acid molecule, methods for inducing apomixis in a plant, methods for the production of apomictic plants and uses thereof. | 04-03-2014 |
20150299727 | Improved Methods for Inducing Apomixis in Plants - The present invention relates to methods for inducing apomixis in a plant, methods for the production of apomictic plants and the plants and plant seeds obtained thereby. | 10-22-2015 |
José M. Gil Cunquero, Jaen ES
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20120308586 | COMPOSITION BASED ON EXTRA VIRGIN OLIVE OILS - This invention relates to a composition based on a mixture of different olive oils, preferably virgin and extra virgin olive oils, from ecological farms, and to the use thereof in the treatment or prevention of different disorders in humans and animals. Moreover, this invention also relates to a dermatological/dermocosmetic preparation that comprises the composition of this invention and to the use of this dermatological/dermocosmetic preparation in the treatment of skin disorders in humans and animals. Underlying these systemic and/or skin disorders, there are metabolic and immunoinflammatory-oxidative alterations, which may be positively modified by the systemic (oral) or topical (cutaneous) use of the composition of this invention. The special physical-chemical structure of the composition allows for a better digestive and cutaneous arrangement. | 12-06-2012 |
José M. Gil Cunquero, Jaen ES
Patent application number | Description | Published |
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20120308586 | COMPOSITION BASED ON EXTRA VIRGIN OLIVE OILS - This invention relates to a composition based on a mixture of different olive oils, preferably virgin and extra virgin olive oils, from ecological farms, and to the use thereof in the treatment or prevention of different disorders in humans and animals. Moreover, this invention also relates to a dermatological/dermocosmetic preparation that comprises the composition of this invention and to the use of this dermatological/dermocosmetic preparation in the treatment of skin disorders in humans and animals. Underlying these systemic and/or skin disorders, there are metabolic and immunoinflammatory-oxidative alterations, which may be positively modified by the systemic (oral) or topical (cutaneous) use of the composition of this invention. The special physical-chemical structure of the composition allows for a better digestive and cutaneous arrangement. | 12-06-2012 |
José M. Gomora Elena, Madrid ES
Patent application number | Description | Published |
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20100216173 | CITRULLINATED FIBRIN-FILAGGRIN CHIMERIC POLYPEPTIDE CAPABLE OF DETECTING THE ANTIBODIES GENERATED IN RHEUMATOID ARTHRITIS - The present invention concerns a chimeric polypeptide, capable of detecting the antibodies generated in rheumatoid arthritis, comprising at least two citrulinated peptide subunits: (i) one derived from the α or β chain of the fibrin and (ii) a second derived from the filaggrin. In addition, the invention comprises an antigenic composition, a method and a kit for the diagnosis of rheumatoid arthritis, from the detection of the autoantibodies generated during the course of said disease. | 08-26-2010 |
José M. Gomora Elena, Madrid ES
Patent application number | Description | Published |
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20100216173 | CITRULLINATED FIBRIN-FILAGGRIN CHIMERIC POLYPEPTIDE CAPABLE OF DETECTING THE ANTIBODIES GENERATED IN RHEUMATOID ARTHRITIS - The present invention concerns a chimeric polypeptide, capable of detecting the antibodies generated in rheumatoid arthritis, comprising at least two citrulinated peptide subunits: (i) one derived from the α or β chain of the fibrin and (ii) a second derived from the filaggrin. In addition, the invention comprises an antigenic composition, a method and a kit for the diagnosis of rheumatoid arthritis, from the detection of the autoantibodies generated during the course of said disease. | 08-26-2010 |
José M. Gonzalez De Buitrago Arriero, Salamanca ES
Patent application number | Description | Published |
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20120220480 | METHOD FOR THE DETECTION OF RENAL DAMAGE - The invention relates to a method for determining the presence of renal damage in an individual and also to a method for detecting one or several proteins selected from the list comprising Reg3B, fetuin B, Ras-related GTP-binding protein A serine protease inhibitor A3L, subunit 1 of COP9, gamma subunit of ATP synthase, gelsolin, ribonuclease UK114, aminoacylase 1A, alpha-enolase, keratin 5, parvalbumin alpha, ribonuclease 4 or serine protease inhibitor A3K. The renal damage may be acute renal failure. Said renal pathologies may be caused by the administration of a nephrotoxic agent, wherein the nephrotoxic agent may be an aminoglycoside antibiotic such as gentamicin, or cisplatin. The invention also provides means to differentiate the renal damage or renal failure induced by gentamicin from that induced by cisplatin, through the biochemical analysis of the urinary level of Reg3B and/or gelsolin, or fragments thereof. | 08-30-2012 |
José M. Guillén-Rodríguez, Tucson, AZ US
Patent application number | Description | Published |
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20110066147 | SYSTEM AND METHOD FOR PREDICTING LESION SIZE SHORTLY AFTER ONSET OF RF ENERGY DELIVERY - Lesion size or volume prediction shortly after the onset of an ablation procedure can inform or control the ablation procedure. The prediction and/or control is made without regard to an actual detected temperature in the vicinity of the ablation electrodes. As a consequence, the system has utility with irrigated catheter constructions and other situations in which local irrigation in the vicinity of an ablation site would otherwise interfere with a prediction or control scheme that solely relies upon temperature measurements. | 03-17-2011 |
José M. Guillén-Rodríguez, Tucson, AZ US
Patent application number | Description | Published |
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20110066147 | SYSTEM AND METHOD FOR PREDICTING LESION SIZE SHORTLY AFTER ONSET OF RF ENERGY DELIVERY - Lesion size or volume prediction shortly after the onset of an ablation procedure can inform or control the ablation procedure. The prediction and/or control is made without regard to an actual detected temperature in the vicinity of the ablation electrodes. As a consequence, the system has utility with irrigated catheter constructions and other situations in which local irrigation in the vicinity of an ablation site would otherwise interfere with a prediction or control scheme that solely relies upon temperature measurements. | 03-17-2011 |
José M. Hoyos Irisarri, Lugo ES
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20130089433 | CONVERTIBLE WIND TURBINE NACELLE COVER - A convertible nacelle cover with an integrated platform for avoiding the use of auxiliary devices when performing maintenance operations on the components of a wind turbine nacelle, in cases in which the nacelle is not large enough to allow workers standing in it. | 04-11-2013 |
José M. Hoyos Irisarri, Lugo ES
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20130089433 | CONVERTIBLE WIND TURBINE NACELLE COVER - A convertible nacelle cover with an integrated platform for avoiding the use of auxiliary devices when performing maintenance operations on the components of a wind turbine nacelle, in cases in which the nacelle is not large enough to allow workers standing in it. | 04-11-2013 |
José M. Lagarón Cabello, Paterna (valencia) ES
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20120301514 | DEVELOPMENT OF BIOACTIVE ELECTROSPUN COATINGS FOR BIOMEDICAL APPLICATIONS - The present invention relates to a bioactive composition obtained through the technique of electrospinning and composed of at least one polymer. Furthermore, the invention also discloses a process for the incorporation of such electrospun bioactive composition, as a coating over a plastic matrix to obtain composite materials for their use in both biodegradable and non-biodegradable biomedical implants and in tissue engineering. | 11-29-2012 |
José M. Lagarón Cabello, Paterna (valencia) ES
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20120301514 | DEVELOPMENT OF BIOACTIVE ELECTROSPUN COATINGS FOR BIOMEDICAL APPLICATIONS - The present invention relates to a bioactive composition obtained through the technique of electrospinning and composed of at least one polymer. Furthermore, the invention also discloses a process for the incorporation of such electrospun bioactive composition, as a coating over a plastic matrix to obtain composite materials for their use in both biodegradable and non-biodegradable biomedical implants and in tissue engineering. | 11-29-2012 |
José M. Llacer Gallach, Jaen ES
Patent application number | Description | Published |
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20120308586 | COMPOSITION BASED ON EXTRA VIRGIN OLIVE OILS - This invention relates to a composition based on a mixture of different olive oils, preferably virgin and extra virgin olive oils, from ecological farms, and to the use thereof in the treatment or prevention of different disorders in humans and animals. Moreover, this invention also relates to a dermatological/dermocosmetic preparation that comprises the composition of this invention and to the use of this dermatological/dermocosmetic preparation in the treatment of skin disorders in humans and animals. Underlying these systemic and/or skin disorders, there are metabolic and immunoinflammatory-oxidative alterations, which may be positively modified by the systemic (oral) or topical (cutaneous) use of the composition of this invention. The special physical-chemical structure of the composition allows for a better digestive and cutaneous arrangement. | 12-06-2012 |
José M. Llacer Gallach, Jaen ES
Patent application number | Description | Published |
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20120308586 | COMPOSITION BASED ON EXTRA VIRGIN OLIVE OILS - This invention relates to a composition based on a mixture of different olive oils, preferably virgin and extra virgin olive oils, from ecological farms, and to the use thereof in the treatment or prevention of different disorders in humans and animals. Moreover, this invention also relates to a dermatological/dermocosmetic preparation that comprises the composition of this invention and to the use of this dermatological/dermocosmetic preparation in the treatment of skin disorders in humans and animals. Underlying these systemic and/or skin disorders, there are metabolic and immunoinflammatory-oxidative alterations, which may be positively modified by the systemic (oral) or topical (cutaneous) use of the composition of this invention. The special physical-chemical structure of the composition allows for a better digestive and cutaneous arrangement. | 12-06-2012 |
José M. Lopez Novoa, Salamanca ES
Patent application number | Description | Published |
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20120220480 | METHOD FOR THE DETECTION OF RENAL DAMAGE - The invention relates to a method for determining the presence of renal damage in an individual and also to a method for detecting one or several proteins selected from the list comprising Reg3B, fetuin B, Ras-related GTP-binding protein A serine protease inhibitor A3L, subunit 1 of COP9, gamma subunit of ATP synthase, gelsolin, ribonuclease UK114, aminoacylase 1A, alpha-enolase, keratin 5, parvalbumin alpha, ribonuclease 4 or serine protease inhibitor A3K. The renal damage may be acute renal failure. Said renal pathologies may be caused by the administration of a nephrotoxic agent, wherein the nephrotoxic agent may be an aminoglycoside antibiotic such as gentamicin, or cisplatin. The invention also provides means to differentiate the renal damage or renal failure induced by gentamicin from that induced by cisplatin, through the biochemical analysis of the urinary level of Reg3B and/or gelsolin, or fragments thereof. | 08-30-2012 |
José M. Martinez Melero, Valencia ES
Patent application number | Description | Published |
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20120309872 | BITUMINOUS MATERIAL AND ITS USE FOR THE CONSTRUCTION OF SUB-BALLAST - The present invention relates to a novel bituminous material using vulcanized rubber powder from out-of-use tires, and the use of the same for the construction of sub-ballast. | 12-06-2012 |
José M. Martinez Melero, Valencia ES
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20120309872 | BITUMINOUS MATERIAL AND ITS USE FOR THE CONSTRUCTION OF SUB-BALLAST - The present invention relates to a novel bituminous material using vulcanized rubber powder from out-of-use tires, and the use of the same for the construction of sub-ballast. | 12-06-2012 |
José M. Martinez-Ortega, Laval CA
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20120165088 | SYSTEM AND METHOD FOR AN INTERACTIVE LOTTERY GAME OVER A NETWORK - A system and method for increasing player odds at the expense of sharing the jackpot. The interactive lottery game consists in forming as many closed groups as possible, i.e., paid lottery entries, by having players wager small amounts in opened groups, i.e., unpaid lottery entries, before the day of the jackpot draw. Three levels of play are controlled by the system: i) random group play, chosen by players to place wagers; ii) customized group play, chosen by players to close specific groups; and iii) interactive group play for players transferring wagers from players' opened groups to other groups according to game strategies. This is a wiser lottery game because represent higher return on investment for players while increasing house profitability. It defines a new interactive lottery game accessible from any portable device or personal computer as long as players are connected to a network. | 06-28-2012 |