Patent application number | Description | Published |
20080294261 | Method for treating herniated discs - A method is effective for treating herniated discs. The method includes (a) surgically remove a herniated portion of disc annulus from a herniated disc, or surgically depressing and holding a herniated portion of disc annulus within original boundaries of the herniated disc, and (b) re-enforcing the surgically treated disc with an effective amount of a biocompatible degradable polymeric compound, such as a fibrin sealant. | 11-27-2008 |
20090054994 | Methods and kits for prophylactically reinforcing degenerated spinal discs and facet joints near a surgically treated spinal section - A method is effective for prophylactically treating discs and facet joints near a spinal section that requires surgery. The method comprises the steps of performing a surgical procedure on a section of a spine, and reinforcing a disc or a facet joint adjacent to the surgically treated area with an effective amount of an injected, in situ curable biocompatible matrix or biocompatible polymeric compound. The procedure delays or prevents the development of permanent or irreversible degenerative changes in the treated disc and/or facet joint, thus offering the spinal surgery patient a higher probability of long-term success for arresting disc and facet joint degeneration and prevention of latent adjacent disc/facet joint problems. | 02-26-2009 |
20090181092 | Methods for Treating Joints and Discs with a Carrier Matrix and Cells - Methods for enhancing pain relief and accelerating repair of painful disruptions associated with damaged and/or degenerated synovial joints and spinal discs are disclosed. These methods include injecting an effective amount of a biocompatible matrix or biocompatible polymeric compound, as well as a plurality of cells, into and/or around the damaged and/or degenerated synovial joints or spinal discs. The plurality of cells may include fibroblast cells, chondrocytes, genetically altered cells, stem cells such as mesenchymal stem cells, or combinations thereof. | 07-16-2009 |
20090181892 | METHODS AND KITS FOR TREATING JOINTS AND SOFT TISSUES - Methods to treat and provide pain relief for damaged and degenerated tissues of a musculoskeletal joint are disclosed. These methods include introducing into, around and/or on the musculoskeletal joint an effective amount of biocompatible matrix or biocompatible polymeric compound to reduce pain associated with the damaged and degenerated tissues of a musculoskeletal joint, wherein at least a portion of it is activated and polymerized in situ. Examples of the musculoskeletal joints include intervertebral joints and synovial joints. | 07-16-2009 |
20090324678 | Methods and kits for treating joints and soft tissues - Methods to treat and provide pain relief for damaged and degenerated tissues of a musculoskeletal joint are disclosed. These methods include introducing into, around and/or on the musculoskeletal joint an effective amount of a pharmaceutical composition containing a biocompatible matrix or biocompatible polymeric compound, a pain reliever, and a corticosteroid formulated for extended-release, wherein at least a portion of the biocompatible matrix or biocompatible polymeric compound is activated and polymerized in situ. Also disclosed is a composition for treating a damaged or degenerated joint or soft tissue. The composition contains a polymerizable material capable of forming a biocompatible and biodegradable matrix in situ at a treatment site, a pain reliever; and a corticosteroid formulated for extended-release. | 12-31-2009 |
20120277867 | Interbody fusion device and associated methods - A medical device comprising a non-enclosed housing configured to fit between two adjacent vertebrae; one or more housing fasteners extending at least partially through the housing, one or more driving mechanisms operationally positioned in relationship to at least one housing fastener, such that activation of at least one driving mechanism engages and drives at least one housing fastener to compress into at least one adjacent vertebrae and one or more plates removably coupled to the housing. | 11-01-2012 |
20120277873 | Interbody fusion device with lipped anterior plate and associated methods - A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention device whose function is to prevent migration of the load bearing device. One or more fasteners secure the retention device to the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion. The second piece can be configured to include lips that abut the apothyseal rings during, with the plate including bores angled such that fasteners penetrate the apothyseal rings. | 11-01-2012 |
20130030547 | Composite Bone Graft Kit - A composite bone graft which comprises an allograft bone component; a synthetic bone substitute, wherein the synthetic bone substitute is in contact with the allograft bone component. The composite is arranged in a core/outer layer structure. | 01-31-2013 |
20150127106 | COMPOSITE BONE GRAFT DEVICE - A composite bone graft which comprises an allograft bone component; a synthetic bone substitute, wherein the synthetic bone substitute is in contact with the allograft bone component. The composite is arranged within a resorbable mesh casing. | 05-07-2015 |
Patent application number | Description | Published |
20080206298 | Enhanced biological autologous tissue adhesive composition and methods of preparation and use - The invention includes a composition useful for preparing a tissue sealant for use on a patient, comprising: autologous fibrinogen, an activating agent and at least one supplement. The invention includes a method of treating a disc having at least one defect, comprising: introducing a composition into the disc, wherein the composition comprises autologous fibrinogen and an activating agent, and wherein the composition forms fibrin. | 08-28-2008 |
20100137816 | Injection of fibrin sealant including an anesthetic in spinal applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 06-03-2010 |
20100143327 | Injection of fibrin sealant including an anesthetic in spinal applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 06-10-2010 |
20100233148 | Injection of fibrin sealant including an anesthetic in spinal applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 09-16-2010 |
20110213464 | INJECTION OF FIBRIN SEALANT IN THE ABSENCE OF CORTICOSTEROIDS IN SPINAL APPLICATIONS - A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 09-01-2011 |
20120156284 | ENHANCED BIOLOGICAL AUTOLOGOUS TISSUE ADHESIVE COMPOSITION AND METHODS OF PREPARATION AND USE - The invention includes a composition useful for preparing a tissue sealant for use on a patient, comprising: autologous fibrinogen, an activating agent and at least one supplement. The invention includes a method of treating a disc having at least one defect, comprising: introducing a composition into the disc, wherein the composition comprises autologous fibrinogen and an activating agent, and wherein the composition forms fibrin. | 06-21-2012 |
20120328600 | INJECTION OF FIBRIN SEALANT USING RECONSTITUTED COMPONENTS IN SPINAL APPLICATIONS - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 12-27-2012 |
20130296777 | Apparatus And Method For Injection Of Fibrin Sealant In Spinal Applications - An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use. | 11-07-2013 |
20140052070 | Injection Of Fibrin Sealant Including An Anesthetic In Spinal Applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 02-20-2014 |
20150245916 | Unitary Spinal Disc Implant - A unitary intervertebral device, having no moving components is provided for non-fusion articulation applications. The interbody articulating device allows for limited flexion and rotation between adjacent vertebrae, helping to preserve or restore near-normal motion between adjacent vertebrae. Rotational motion is achieved through one or more protrusions incorporated into the spinal interbody device. In one articulating form, a first protrusion extends perpendicularly from the superior aspect of the disc-shaped interbody device to form a spike or rotational protrusion, while a second protrusion extends axially from the inferior aspect of the interbody device to form a second spike or rotational protrusion. Protrusions preferably extend perpendicular from the apex of both the first and second arcuate articulating surfaces. In another form, a single protrusion extends axially from the superior aspect of a circular-shape of the interbody device to form a spike or anchoring protrusion, while the inferior surface may be slightly rounded and/or comprising a bone-ingrowth promoting surface. In another form, one or both of the first and/or second arcuate surfaces may be highly polished. Numerous planar geometries are described to define various profiles of the disc replacement implant which may be utilized, including irregular Reuleaux polygons. Numerous variations of the disc replacement and methods of use are described. Similarly configured fusion salvage devices are also described. | 09-03-2015 |