Hagit
Hagit Ashush, Ashkelon IL
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20110190380 | METHODS FOR DELIVERY OF SIRNA TO BONE MARROW CELLS AND USES THEREOF - The present invention relates to a method for the delivery of therapeutic oligonucleotides to bone marrow, and in particular delivery of siRNA to a subset of bone marrow cells. The method comprises systemically administering siRNA to a subject in need thereof, to reduce or inhibit expression of a gene associated with a disease or disorder or to symptoms associated with a disease or disorder associated with the cells. The invention further relates to chemically modified siRNA compounds, to pharmaceutical compositions comprising such compounds and to methods of using such compounds and compositions in the treatment of disease. | 08-04-2011 |
Hagit Avsian, Charlotte, NC US
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20130023072 | Substrate For Integrated Modules - A method of fabricating a plurality of components using wafer-level processing can include bonding first and second wafer-level substrates together to form a substrate assembly, such that first surfaces of the first and second substrates confront one another, the first substrate having first electrically conductive elements exposed at the first surface thereof, forming second electrically conductive elements contacting the first conductive elements, and processing the second substrate into individual substrate elements. The second conductive elements can extend through a thickness of the first substrate and can be exposed at a second surface thereof opposite the first surface. The processing can include trimming material to produce the substrate elements at least some of which have respective different controlled thicknesses between first surfaces adjacent the first substrate and second surfaces opposite therefrom. | 01-24-2013 |
Hagit Eldar-Finkelman, Shoham IL
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20080312188 | Glycogen synthase kinase-3 inhibitors - Novel compounds designed to allow interactions with binding sites of GSK-3 and hence are capable of inhibiting GSK-3 activity, via inhibition of substrate binding are disclosed. Further disclosed are pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions. | 12-18-2008 |
20090062180 | Glycogen synthase kinase-3 inhibitors - Novel conjugates that are capable of inhibiting GSK-3 activity, a process of producing same, pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions are disclosed. Methods of treating affective disorders using GSK-3 inhibitors are further disclosed. | 03-05-2009 |
20130303441 | GLYCOGEN SYNTHASE KINASE-3 INHIBITORS - Novel peptide inhibitors of GSK-3, compositions containing same and uses thereof are disclosed. The novel peptide inhibitors are substrate-competitive inhibitors and have an amino acid sequence designed so as to bind to a defined binding site subunit in GSK-3. | 11-14-2013 |
20130310303 | GLYCOGEN SYNTHASE KINASE-3 INHIBITORS - Novel peptide inhibitors of GSK-3, compositions containing same and uses thereof are disclosed. The novel peptide inhibitors are substrate-competitive inhibitors and have an amino acid sequence designed so as to bind to a defined binding site subunit in GSK-3. Also disclosed are GSK-3 substrate competitive inhibitors which bind to the defined binding site subunit in the enzyme. Also disclosed are mutants of GSK-3 and uses thereof for identifying a putative GSK-3 substrate competitive inhibitor. | 11-21-2013 |
Hagit Elmaleh, Paris FR
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20150322014 | METHOD OF PREPARATION OF CRYSTAL FORMS OF 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDOPYRIDYN-4-YL)-5-METHOXYPYRI- DINE-2-CARBOXAMIDE AND CRISTAL FORMS THEREOF - The present invention relates to a process of preparation of Crystal Forms of 4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxidopyridin-4-yl)-5-methoxypyridine-2-carboxamide of formula (I), said Crystal Forms which are designated as Crystal Forms A to I A and their use as a medicament. | 11-12-2015 |
Hagit Elmaleh, Ormesson Sur Marne FR
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20110144362 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME - The invention relates to anhydrides, solvates and ethanol hetero-solvates and hydrates of dimethoxy docetaxel or (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β, 10β-dimethoxy-9-oxo-tax-11-ene-13α-yl, and to the preparation thereof. | 06-16-2011 |
20130178639 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME - The invention relates to anhydrides, solvates and ethanol hetero-solvates and hydrates of dimethoxy docetaxel or (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β, 10β-dimethoxy-9-oxo-tax-11-ene-13α-yle, and to the preparation thereof. | 07-11-2013 |
20140350272 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME - The invention relates to anhydrides, solvates and ethanol hetero-solvates and hydrates of dimethoxy docetaxel or (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β, 10β-dimethoxy-9-oxo-tax-11-ene-13α-yle, and to the preparation thereof. | 11-27-2014 |
Hagit Frankel-Mullerad, Galil Ma'Aravi IL
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20130177485 | DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY - A diagnostic device is provided for distinguishing between amniotic fluid and urine in female secretion. The device can be employed as a panty shield or can be adhered onto a panty shield or can be employed in a simple pad that is pressed against a substrate provided with female secretion. | 07-11-2013 |
Hagit Frenkel-Mullerad, Galil-Ma'Aravi IL
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20110065139 | DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY - A diagnostic device is provided for distinguishing between amniotic fluid and urine in female secretion. The device can be employed as a panty shield or can be adhered onto a panty shield or can be employed in a simple pad that is pressed against a substrate provided with female secretion. | 03-17-2011 |
Hagit Gershtenman-Avsian, Huntersville, NC US
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20110181854 | FOCUS COMPENSATION FOR OPTICAL ELEMENTS AND APPLICATIONS THEREOF - Optical imaging apparatus are provided having the desired focal properties, which can be manufactured and/or assembled at the wafer level. | 07-28-2011 |
Hagit Hamdani, Haifa IL
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20110066686 | Public BOT Management in Private Networks - A system for managing the use of BOTs by computer network users, the system including a gateway-to-BOT communications manager configured to relay communications to a BOT on behalf of a computer user in a manner that prevents the BOT from associating the communications with the computer user, and a gateway-to-user communications manager configured to relay the communications from the computer user to the gateway-to-BOT communications manager, and relay to the computer user communications received from the gateway-to-BOT communications manager that originate from the BOT. | 03-17-2011 |
20120284323 | PUBLIC BOT MANAGEMENT IN PRIVATE NETWORKS - A system for managing the use of BOTs by computer network users, the system including a gateway-to-BOT communications manager configured to relay communications to a BOT on behalf of a computer user in a manner that prevents the BOT from associating the communications with the computer user, and a gateway-to-user communications manager configured to relay the communications from the computer user to the gateway-to-BOT communications manager, and relay to the computer user communications received from the gateway-to-BOT communications manager that originate from the BOT. | 11-08-2012 |
Hagit Koren-Lichtig, Moshav Mishmeret IL
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20150118280 | BIOACTIVE COMPOUNDS PROTECTION METHOD AND COMPOSITIONS CONTAINING THE SAME - The present invention relates to means for protecting bioactive materials in mammalian food or feed formulations used to enhance the health status of mammals. | 04-30-2015 |
20150238573 | NUTRITIONAL FOOD AND FEED, COMPOSITION, PROCESSING AND METHOD OF USE - The present invention relates to means for protecting and incorporating bioactive compounds in food or feed formulations used to enhance the health status and growth performance of human and non-human organisms. | 08-27-2015 |
Hagit Krug, Bar Yam IL
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20110274647 | IL6R/IL6 Chimera for Therapy of Chemotherapy-Induced Peripheral Neuropathy - The invention relates to the use of IL-6R/IL-6 chimera in chemotherapy induced neuropathy. | 11-10-2011 |
Hagit Messer-Yaron, Kfar Saba IL
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20090160700 | Monitoring and Mapping of Atmospheric Phenomena - A computerized system for mapping an atmospheric phenomenon in a geographic region. Multiple free-space electromagnetic communications links are previously distributed in the geographic region. The system includes an interface to monitoring mechanisms attached respectively to the free-space electromagnetic communications links. The monitoring mechanisms respectively monitor attenuation levels of the free-space electromagnetic communications links. A processor simultaneously processes the attenuation levels, and maps in the geographic region the atmospheric phenomenon. The simultaneous processing preferably applies a non-linear model which relates the attenuation levels the atmospheric phenomenon, and solves a tomographic problem based on the non-linear model and the attenuation levels. The tomographic problem is preferably solved by an interactive algorithm based on consecutive refinement and linear inversion at each iteration. Alternatively, an interpolation is performed based on respective inverse distance from the communications links. Preferably, the interpolation is further based on respective lengths of communications links. A data interface preferably provides to subscribers temporal information related to the atmospheric phenomenon within portions of the geographic region. | 06-25-2009 |
Hagit Peretz-Soroka, Ramat-Gan IL
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20130224789 | METHODS OF MONITORING AND ANALYZING METABOLIC ACTIVITY PROFILES DIAGNOSTIC AND THERAPEUTIC USES OF SAME - A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: | 08-29-2013 |
20140255972 | METHODS OF MONITORING AND ANALYZING METABOLIC ACTIVITY PROFILES DIAGNOSTIC AND THERAPEUTIC USES OF SAME - A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: | 09-11-2014 |
Hagit Shilo-Volin, Meytar IL
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20110008267 | Pharmaceutical and Cosmeceutical Wash-Off Mousse Shampoo Compositions, Processes for Preparing the Same and Uses Thereof - A method for treating a disease or disorder of the skin or scalp of a mammal while simultaneously cleansing the skin or scalp is disclosed. The method includes administering to the skin or scalp a mousse formed from a composition that includes a therapeutically or cosmeceutically effective amount of at least one active pharmaceutical ingredient, 10% to 50% by weight of a cleansing agent selected from the group consisting of anionic surfactants, nonionic surfactants and combinations thereof, a pharmaceutically acceptable mousse-forming carrier that includes a propellant, the propellant being 3% to 50% by weight of the composition, and water being about 40% to about 90% by weight of the composition, waiting a period of time; and rinsing said skin or scalp with water to remove the mousse. | 01-13-2011 |