Patent application number | Description | Published |
20090131643 | Rapid metal organic framework molecule synthesis method - A rapid, simple and versatile metal organic framework molecule (MOF) synthesis method particularly adapted to make non-linear MOFs includes heating MOF precursors, such as a metal or metal oxide and an organic ligand, in a microwave oven for a period sufficient to achieve crystallization. Microwave-assisted MOF synthesis yields high quality MOF crystals in a reaction time ranging from about 5 seconds to about 2.5 minutes, compared to hours and days required in conventional solvothermal and hydrothermal methods. In addition, microwave assisted methods provide MOF materials with uniform crystal size and well-defined shape. Further, microwave synthesis of MOFs allows the size and shape of MOF crystals to be tailored for use in a wide range applications by manipulating reaction conditions. Secondary growth processes may also be employed to grow larger crystals using seeds obtained from microwave-assisted synthesis methods. | 05-21-2009 |
20090211452 | Micromachined Gas Chromatography Columns For Fast Separation of Organophosphonate and Organosulfur Compounds and Methods for Deactivating Same - Improved microcolumns and methods for producing microcolumns particularly suitable for use in gas chromatographs are disclosed. In particular, following deposition of the stationary phase coating, the microcolumns are subjected to a postcoating treatment with a molecule that binds to the active sites in the stationary phase column thereby eliminating or reducing loss of gas chromatograph performance associated with those active sites. The postcoating treatment molecule binds to the same active sites as the analytes of interest. | 08-27-2009 |
20100132547 | HIGH GAIN SELECTIVE METAL ORGANIC FRAMEWORK PRECONCENTRATORS - Novel metal organic framework (MOF) molecules and methods of synthesizing them are described. MOFs are organometallic crystalline structures that have high sorption capacity due to high surface area, tailorable selectivity, an inert nature, and thermal stability at high temperatures. MOFs may be used as sorbents in preconcentrators for analytical devices to provide orders of magnitude of improved sensitivity in analyte detection. MOFs are also useful as sorbents in new compact and portable micropreconcentrator designs such as a modified purge and trap system and a multi-valve microelectromechanical system (MEMS) to achieve high gain in analyte detection. Further, MOFs may be used as coatings for novel microstructure arrays in micropreconcentrators where the microstructures are designed to increase the surface area to volume ratio inside the micropreconcentrator while minimizing the pressure drop across the micropreconcentrator. | 06-03-2010 |
20110284394 | Portable Electrochemical Multiphase Microreactor for Sensing Trace Chemical Vapors - A multiphase microreactor includes gas and liquid microchannels separated by a nanoporous membrane. Rapid mass transfer of gas samples into the liquid electrolyte allows the microchannel/membrane assembly to be used as a fast and sensitive gas sensor. When the oxime chemistry is adapted into the microchannel sensor, the microchannel sensor selectively responds to organophosphates and organophosphate simulants. In addition, a double microchannel design may be used to reduce voltage drift and incorporate a reference electrode into the sensor assembly. Methods of detecting organophosphates are also disclosed. | 11-24-2011 |
20120212242 | Graphene-Based Sensor - Sensors containing Graphene with Extended Defects are described. | 08-23-2012 |
20120308903 | Novel Catalyst Mixtures - Catalysts that include at least one catalytically active element and one helper catalyst can be used to increase the rate or lower the overpotential of chemical reactions. The helper catalyst can simultaneously act as a director molecule, suppressing undesired reactions and thus increasing selectivity toward the desired reaction. These catalysts can be useful for a variety of chemical reactions including, in particular, the electrochemical conversion of CO | 12-06-2012 |
20130015064 | Sensors For Carbon Dioxide And Other End Uses - Electrochemical sensors measure an amount or concentration of CO | 01-17-2013 |
20130023404 | Novel Catalyst Mixtures - Catalyst mixtures include at least one Catalytically Active Element and, as a separate constituent, one Helper Catalyst. The catalysts can be used to increase the rate, modify the selectivity or lower the overpotential of chemical reactions. These catalysts are useful for a variety of chemical reactions including, in particular, the electrochemical conversion of CO | 01-24-2013 |
20130075273 | On Demand Carbon Monoxide Generator For Therapeutic and Other Applications - A device that can produce carbon monoxide for therapeutic and laboratory applications is disclosed. The device includes and electrochemical cell that converts carbon dioxide or a carbon dioxide containing molecule such as a carbonate or bicarbonate or bicarbonate into carbon monoxide and oxygen. The cell contains additives so pure carbon monoxide is obtained. | 03-28-2013 |
20130157174 | Electrocatalysts For Carbon Dioxide Conversion - Electrocatalysts for carbon dioxide conversion include at least one catalytically active element with a particle size above 0.6 nm. The electrocatalysts can also include a Helper Catalyst. The catalysts can be used to increase the rate, modify the selectivity or lower the overpotential of electrochemical conversion of CO | 06-20-2013 |
20140093799 | Devices And Processes For Carbon Dioxide Conversion Into Useful Fuels And Chemicals - Electrochemical devices for converting carbon dioxide to useful reaction products include a solid or a liquid with a specific pH and/or water content. Chemical processes using the devices are also disclosed, including processes to produce CO, HCO | 04-03-2014 |
20140239231 | Carbon Dioxide Conversion To Fuels And Chemicals - An environmentally beneficial process for the production of fuels and chemicals employs carbon dioxide from a natural source or from an artificial chemical source that would otherwise be discharged into the environment. The carbon dioxide is converted to formic acid and the formic acid is then non-biologically converted to fuels and/or chemicals without the intermediate process of hydrogenating the formic acid to methanol or reacting the formic acid with ammonia to form formamide. In the present process, formic acid is converted to one of seven primary feedstocks: formaldehyde, acrylic acid, methane, ethylene, propylene, syngas, and C5-C7 carbohydrates. The formaldehyde, acrylic acid, methane, ethylene, propylene, syngas and/or short chain carbohydrates can either be used directly, or can be converted into a wealth of other products. | 08-28-2014 |
20150122640 | Electrochemical Devices Employing Novel Catalyst Mixtures - An electrochemical device comprises an anode and a cathode. An electrocatalyst mixture is placed between said anode and cathode. The electrocatalyst mixture comprises at least one Catalytically Active Element and, separately, at least one Helper Catalyst comprising an organic molecule, an organic ion, or a mixture of organic molecules and organic ions. The electrocatalyst mixture electrochemically converts carbon dioxide to one or more carbonaceous reaction products via the reaction: CO | 05-07-2015 |
20150209722 | Electrocatalytic Process For Carbon Dioxide Conversion - An electrocatalytic process for carbon dioxide conversion includes combining a Catalytically Active Element and Helper Catalyst in the presence of carbon dioxide, allowing a reaction to proceed to produce a reaction product, and applying electrical energy to said reaction to achieve electrochemical conversion of said reactant to said reaction product. The Catalytically Active Element can be a metal in the form of supported or unsupported particles or flakes with an average size between 0.6 nm and 100 nm. the reaction products comprise at least one of CO, HCO | 07-30-2015 |
20150376802 | Electrochemical Devices Comprising Novel Catalyst Mixtures - Electrochemical devices comprising electrocatalyst mixtures include at least one Catalytically Active Element and, as a separate constituent, one Helper Catalyst. The electrocatalysts can be used to increase the rate, modify the selectivity or lower the overpotential of chemical reactions. These electrocatalysts are useful for a variety of chemical reactions including, in particular, the electrochemical conversion of CO | 12-31-2015 |
Patent application number | Description | Published |
20100158923 | REDUCING POLYGLUTAMINE-BASED AGGREGATION - The disclosure features, inter alia, methods for treating or preventing neurodegenerative disorders and disorders that caused at least in part by polyglutamine aggregation. The method can include reducing activity of the IGF-1/GH axis in a subject. One exemplary neurodegenerative disorder that is also caused at least in part by polyglutamine aggregation is Huntington's disease. | 06-24-2010 |
20110123512 | METHOD OF REGULATING THE HEAT SHOCK RESPONSE - The present invention is directed to method of modulating a heat shock response in a first cell of a multicellular organism comprising stimulating or inhibiting an HSR signaling activity of a second cell, wherein the second cell is a neuronal cell that regulates heat shock response activation in the first cell and that does not directly innervate the first cell. | 05-26-2011 |
20110237907 | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS - The present invention relates to the identification of compounds and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided compounds. | 09-29-2011 |
20110311508 | METHOD OF MODULATING HSF-1 - The present invention is directed to methods of modulating HSF1 activity comprising modifying the acetylation of the DNA binding domain of the HSF1. | 12-22-2011 |
20120046309 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS - The present invention relates to the identification of inventive pyrimidine-2,4,6-triones (PYT compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the inventive PYT compounds. | 02-23-2012 |
20120264765 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis - The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds. | 10-18-2012 |
20130310439 | METHOD OF REDUCING PROTEINS MISFOLDING AND/OR AGGREGATION - The present invention is directed to methods of reducing protein misfolding and/or aggregation in a subject and to method of treating a condition mediated by a dysfunction in protein homeostasis comprising modulating cholinergic signaling activity. | 11-21-2013 |
20140371313 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis - The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds. | 12-18-2014 |
20150203456 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS - The present invention relates to the identification of inventive pyrimidine-2,4,6-triones (PYT compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the inventive PYT compounds. | 07-23-2015 |