Patent application number | Description | Published |
20120067244 | Less than lethal projectile and a method for producing the same - A less than lethal projectile and method of producing the same comprising of a sealed filled polymeric pouch containing a shot within. The sealed filled polymeric pouch is formed in a form, fill, and seal machine. An automatic loading ammunition machine is fed empty shell casings; the ammunition machine automatically loads the empty shell casing with pre-determined quantities of wad, primer, and gun powder, and subsequently moves the sealed filled polymeric pouch into a projectile compartment of the empty shell casing producing a fully-loaded shell casing to be loaded into a barrel of an ammunition. The polymeric pouch is capable of being inserted into various shell casings depending on the intended use thus allowing for officers and soldiers to select from an array of munitions when confronted with a situation where less than lethal means are required. | 03-22-2012 |
20120076263 | Method And Apparatus For Scanning Objects In Transit - A method and apparatus for identifying hazardous material or potential dangers. The method and apparatus is directed to a non-destructive, non-intrusive scanning system that uses a dual energy x-ray scanning apparatus to transmit and display data within a computer system. The software within the computer system provides for scan data transfer, a cataloging of image data and real time analytics. The real time analytics will find data from a watch list and correlate the data to the scan; it will also compare the scan data to a reference library, and it will additionally perform advanced pattern correlations to look for unusual and or suspicious patterns. | 03-29-2012 |
20120240807 | Less Than Lethal Cartridge - A less than lethal cartridge for a projectile which when fired has a velocity which will not kill an individual struck by the projectile. The less than lethal cartridge has a rim which is deeper or thicker than a rim on a conventional lethal cartridge. The caliber of the cartridge is also selected so that regular lethal ammunition is not available in this caliber. The preferred caliber of the less than lethal cartridge is .490. The less than lethal cartridge contains a polymeric projectile or alternatively, a sealed filled polymeric pouch containing shot therein. | 09-27-2012 |
20120279106 | Reduced lethality gun - A gun that has a plurality of frangible barrels. At the proximal end of each barrel is a chamber that receives a cartridge. The cartridge has a reduced charge as compared to a conventional cartridge. Each barrel may have an inner sleeve formed from a malleable material. The out member of each barrel is comprised of a rigid material such as, but not limited to, a filled plastic. The inner sleeve is rigid enough to withstand the pressure of the reduced charge cartridge when fired, but is malleable enough to expand from the pressure generated by a standard charge cartridge. When the inner sleeve expands, the outer member fragments and destroys the weapon. The expansion of the inner sleeve and fragmentation of the outer member upon firing a standard charge reduces the propelling force in the bullet. As a result, the weapon is destroyed and the bullet is fired with a greatly reduced force. The barrels on the gun don not rotate. The hammer is mounted in a revolving mechanism that is rotated in a circular path from one barrel to the next when the trigger is pulled. Pulling the trigger also compresses and then releases a revolving member that forces the hammer into contact with one of the firing pins. | 11-08-2012 |
20130111797 | Multiple cartridge assembly for less than lethal cartridge - A multiple cartridge assembly is described which facilitates speed loading of a four barrel less than lethal gun. Four less than lethal cartridges are attached to the multiple cartridge assembly and arranged to correspond with the breech of a four barrel less than lethal gun. Each less than lethal cartridge is constructed with a projectile which when fired has a velocity which will not kill an individual struck by the projectile. The less than lethal cartridge has a rim which is deeper or thicker than a rim on a conventional lethal cartridge. The caliber of the cartridge is also selected so that regular lethal ammunition is not available in this caliber. The preferred caliber of the less than lethal cartridge is 0.490. The less than lethal cartridge contains a polymeric projectile or alternatively, a sealed filled polymeric pouch containing shot therein. | 05-09-2013 |
Patent application number | Description | Published |
20090219784 | Method and Apparatus for Investigating a Borehole with a Caliper - Embodiments of the present invention relate to a caliper and method for mapping the dimensions and topography of a formation such as the sidewall of a borehole. Examples of formations in which embodiments of the invention can be used include, but are not limited to, an oil, gas, pile borehole or barrette that has been drilled or excavated into the earth. | 09-03-2009 |
20110056303 | METHOD AND APPARATUS FOR TESTING LOAD-BEARING CAPACITY UTILIZING A RING CELL - An annular assembly, or ring cell, is provided for testing the load bearing capacity of piles. The ring cell walls of the annular assembly can be made of stamped material. The ring cell walls can be an outer ring wall and an inner ring wall. Alternately, the ring cell walls can have a “U”-type shape cross-section including an outer ring wall, an inner ring wall, and a top wall. Fluid can be provided to the annular assembly through fluid supply lines into an expansion zone. The expansion zone can be a space having a bladder for filling with fluid. In another embodiment, the expansion zone can be a space between a filler material capable of withstanding high pressure separated with a membrane. The pressure of the fluid in the expansion zone can be monitored during testing. | 03-10-2011 |
20110283805 | METHOD AND APPARATUS FOR TESTING LOAD-BEARING CAPACITY - In an embodiment, a hydraulic jack is provided having a first portion and a second portion. The first portion attached to a first section of a structure and the second portion attached to a second section of the structure. When a pressurized fluid is forced between the first portion and the second portion, a load is transferred to the first section and the second section by the pressure of the fluid on the first portion and the second portion. The first section and the second section are forced apart by the load, thus creating or enlarging at least one void in the structure. The pressurized fluid fills or partially fills one or more of the at least one void, thereby increasing the surface area effectively normal to the direction of the load in contact with the pressurized fluid. | 11-24-2011 |
20110283816 | METHOD AND APPARATUS FOR INTERNALLY DETERMINING A LOAD APPLIED BY A JACK - An embodiment of the subject invention is directed to a jack incorporating one or more strain gauges. The one or more strain gauges can be positioned on, within, or integral to the jack. When a load or force is applied by the jack, one or more materials within the jack are deformed or displaced as a result of the applied load. The one or more strain gauges are used to measure the deformation or displacement and thus measure the strain. The measured strain can be used to determine the magnitude of the load applied by the jack. In an embodiment, a plurality of strain gauges are used and the resulting strain measurements can be combined to determine the applied load. | 11-24-2011 |
20120090401 | METHOD AND APPARATUS FOR TESTING LOAD-BEARING CAPACITY - In an embodiment, a hydraulic jack is provided having a first portion and a second portion. The first portion attached to a first section of a structure and the second portion attached to a second section of the structure. When a pressurized fluid is forced between the first portion and the second portion, a load is transferred to the first section and the second section by the pressure of the fluid on the first portion and the second portion. The first section and the second section are forced apart by the load, thus creating or enlarging at least one void in the structure. The pressurized fluid fills or partially fills one or more of the at least one void, thereby increasing the surface area effectively normal to the direction of the load in contact with the pressurized fluid. | 04-19-2012 |
20130068033 | METHOD AND APPARATUS FOR TESTING LOAD-BEARING CAPACITY UTILIZING A RING CELL - An annular assembly, or ring cell, is provided for testing the load bearing capacity of piles. The ring cell walls of the annular assembly can be made of stamped material. The ring cell walls can be an outer ring wall and an inner ring wall. Alternately, the ring cell walls can have a “U”-type shape cross-section including an outer ring wall, an inner ring wall, and a top wall. Fluid can be provided to the annular assembly through fluid supply lines into an expansion zone. The expansion zone can be a space having a bladder for filling with fluid. In another embodiment, the expansion zone can be a space between a filler material capable of withstanding high pressure separated with a membrane. The pressure of the fluid in the expansion zone can be monitored during testing. | 03-21-2013 |
20130247679 | METHOD AND APPARATUS FOR TESTING LOAD-BEARING CAPACITY - In an embodiment, a hydraulic jack is provided having a first portion and a second portion. The first portion attached to a first section of a structure and the second portion attached to a second section of the structure. When a pressurized fluid is forced between the first portion and the second portion, a load is transferred to the first section and the second section by the pressure of the fluid on the first portion and the second portion. The first section and the second section are forced apart by the load, thus creating or enlarging at least one void in the structure. The pressurized fluid fills or partially fills one or more of the at least one void, thereby increasing the surface area effectively normal to the direction of the load in contact with the pressurized fluid. | 09-26-2013 |
20130333487 | METHOD AND APPARATUS FOR INTERNALLY DETERMINING A LOAD APPLIED BY A JACK - An embodiment of the subject invention is directed to a jack incorporating one or more strain gauges. The one or more strain gauges can be positioned on, within, or integral to the jack. When a load or force is applied by the jack, one or more materials within the jack are deformed or displaced as a result of the applied load. The one or more strain gauges are used to measure the deformation or displacement and thus measure the strain. The measured strain can be used to determine the magnitude of the load applied by the jack. In an embodiment, a plurality of strain gauges are used and the resulting strain measurements can be combined to determine the applied load. | 12-19-2013 |
Patent application number | Description | Published |
20080311036 | Imaging of Neural and Organ Injury or Damage - In vivo determination of regional damage with neural and organ injury specific imaging agents. Rapid, and non-invasive imaging compositions and methods for assessment of the extent of neurotoxic cell loss or nervous system damage resulting from nervous system injury due to ischemia, stroke, trauma, chemical or electrical insult, acute drug overdose or exposure to substance abuse (such as “recreational drugs”) infection or other insults. The same or similar rapid, and non-invasive imaging compositions and methods for assessment of the extent of the organ injury comprises any damage, injury or infection, functional failure to specific organs such as liver, kidney, prostate, lung, skeletal muscle, heart, pancreas, stomach, small and large intestine, bladder and the reproductive system as well as damage, injury or infection, functional failure to multi-organs, trauma-hemorrhagic shock and sepsis. In particular, neural and organ damage is detected via protease inhibitor-based radionuclide-labeled imaging ligand binding to overactivated proteases (calpains, caspases, cathepsins, proteasome, metalloproteases, granzyme B or other proteases) that are specific to neural or organ injury or damage. | 12-18-2008 |
20100047817 | Synaptotagmin and Collapsin Response Mediator Protein as Biomarkers for Traumatic Brain Injury - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological fluids after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (CSF). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 02-25-2010 |
20100196942 | BIOMARKERS OF LIVER INJURY - Novel, sensitive and specific markers for diagnostics and monitoring of liver injuries, including, but not limited to ischemic liver damage, are provided. This includes identification several enzymes of arginine/urea/nitric oxide cycle, sulfuration enzymes and spectrin breakdown related products, among others. | 08-05-2010 |
20120196307 | SYNAPTOTAGMIN AND COLLAPSIN RESPONSE MEDIATOR PROTEIN AS BIOMARKERS FOR TRAUMATIC BRAIN INJURY - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological samples after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (biological samples). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 08-02-2012 |
Patent application number | Description | Published |
20110082203 | PROCESS TO DIAGNOSE OR TREAT BRAIN INJURY - A process for diagnosing and treating a neurological condition in a subject is provided that includes assaying a biological sample of a subject for the presence of one or more biomarkers; diagnosing a neurological condition based on a ratio of one or more of the biomarkers in the sample; and administering a therapeutic to the subject to alter the ratio of one or more biomarkers. The diagnosis numerous neurological conditions such as brain injury, or multiple organ injury is provided. | 04-07-2011 |
20110143375 | BIOMARKER DETECTION PROCESS AND ASSAY OF NEUROLOGICAL CONDITION - The subject invention provides a robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject. The invention provides measurement of two or more biomarkers in a biological fluid such as CSF or serum resulting in a synergistic mechanism for determining the extent of neurological damage in a subject with an abnormal neurological condition and for discerning subtypes thereof or tissue types subjected to damage. | 06-16-2011 |
20110191039 | SHOCK WAVE GENERATOR FOR BIOMEDICAL STUDIES - A process of measuring blast shock includes exposing a shock model to an output of a shockwave generator. The propagation of the output is sensed with a sensor platform to generate sensor wave propagation data. The data recorded by the sensor platform is analyzed to measure the blast shock. The blast shock alone or as a component of a cumulative blast exposure can be correlated with an injury metric. A system for measuring cumulative blast shock is provided that includes a sensor platform and an algorithm operating on a microprocessor for analyzing the data recorded by the sensor platform to measure the cumulative blast exposure to injury metrics. | 08-04-2011 |
20120202231 | SYNERGISTIC BIOMARKER ASSAY OF NEUROLOGICAL CONDITION USING S-100B - Processes and assays are provided for detecting and determining the magnitude of traumatic brain injury such as that from impact or percussive trauma or stroke. The inventive assays and processes recognize a synergistic correlation between detection of S-IOOb and one or more other injury specific biomarkers. | 08-09-2012 |
20130022982 | MICRO-RNA, AUTOANTIBODY AND PROTEIN MARKERS FOR DIAGNOSIS OF NEURONAL INJURY - Processes and materials are provided for the detection, diagnosis, or determination of the severity of a neurological injury or condition, including traumatic brain injury, multiple-organ injury, stroke, Alzeimer's disease, Pakinson disease and Chronic Traumatic Encephalopathy (CTE). The processes and materials include biomarkers detected or measured in a biological sample such as whole blood, serum, plasma, or CSF. Such biomarkers include Tau and GFAP proteins, their proteolytic breakdown products, brain specific or enriched micro-RNA, and brain specific or enriched protein directed autoantibodies. The processes and materials are operable to detect the presence of absence of acute, subacute or chronic brain injuries and predict outcome for the brain injury. | 01-24-2013 |
20130029362 | MARKERS AND ASSAYS FOR DETECTION OF NEUROTOXICITY - A process and assay for diagnosing neurotoxicity in a subject is provided. The extent of a neurotoxic insult to a subject is assessed through the measurement of one or more biomarkers in a biological fluid, such as CSF or serum. Other uses and advantages afforded include pre-market drug discovery, monitoring, drug neurotoxicity screening and post market assessment of safety and monitoring for drug of known potential neurotoxicity. | 01-31-2013 |
20140018299 | METHOD AND DEVICE TO DETECT, MONITOR AND PROMOTE NEURAL REGENERATION AND IMPROVEMENT OF COGNITIVE FUNCTION IN A SUBJECT SUFFERING FROM NEURAL INJURY - Severe traumatic brain (TBI) injuries are often associated with long-term and disabling consequences. Prognosis and chronic treatment planning following severe TBI remain challenging. The discovery of specific brain biomarkers could create new opportunities for more accurate clinical assessments identifying groups that may experience better outcomes when exposed to an intervention. The present invention provides a method of detection of Microtubule-associated protein-2 (MAP-2), a marker of dendritic damage, in a biological sample of survivors after TBI and evaluates the recovery of the patient, including an improvement in cognitive abilities and function. | 01-16-2014 |
20140024053 | METHODS, KITS AND DEVICES FOR DETECTING BII-SPECTRIN, AND BREAKDOWN PRODUCTS THEREOF, AS BIOMARKERS FOR THE DIAGNOSIS OF NEURAL INJURY - The present invention identifies biomarkers that are diagnostic of neural injury, neuronal disorder or neurotoxicity and is related to the discovery that proteases are selectively activated in subjects suffering from nervous system damage as compared to healthy subjects. Breakdown products reflecting protease activation are produced and detection of these different biomarkers of the invention is also diagnostic of the degree of severity and type of nerve damage in a subject. | 01-23-2014 |
20140275294 | DEVICES AND METHODS FOR BIOMARKER DETECTION PROCESS AND ASSAY OF LIVER INJURY - An in vitro diagnostic (IVD) device is used to detect the presence of and/or severity of liver injury in a subject. The IVD device relies on an immunoassay which identifies biomarkers that are diagnostic of liver injury in a biological sample, such as whole blood, plasma, serum. The inventive IVD device may measure one or more of several specific markers in a biological sample and output the results to a machine readable format wither to a display device or to a storage device internal or external to the IVD. | 09-18-2014 |
20140342381 | DEVICES AND METHODS FOR BIOMARKER DETECTION PROCESS AND ASSAY OF NEUROLOGICAL CONDITION - The present invention relates to an exemplary in vitro diagnostic (IVD) device used to detect the presence of and/or severity of neural injuries or neuronal disorders in a subject. The IVD device relies on an immunoassay which identifies biomarkers that are diagnostic of neural injury and/or neuronal disorders in a biological sample, such as whole blood, plasma, serum, cerebrospinal fluid (CSF). The inventive IVD device may measure one or more of several neural specific markers in a biological sample and output the results to a machine readable format wither to a display device or to a storage device internal or external to the IVD. | 11-20-2014 |