Patent application number | Description | Published |
20110202100 | Defibrillator Display - Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR) are described herein. | 08-18-2011 |
20110202101 | Defibrillator Charging - Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR). | 08-18-2011 |
20110284004 | WIRELESS VENTILATOR REPORTING - A medical ventilation monitoring system includes a patient ventilation unit defining an airflow path, the unit arranged so that when the unit is applied to a patient, the airflow path is in fluid communication with the patient's airway; an airflow sensor in the air flow path positioned to sense the presence of ventilation airflow to or from the patient; and a wireless transceiver arranged to receive data that is generated by a portable medical device, and to use the data to provide feedback to a rescuer regarding proper administration of ventilation. | 11-24-2011 |
20120010543 | Defibrillator Display Including CPR Depth Information - Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR) are described herein. | 01-12-2012 |
20120302910 | WIRELESS VENTILATOR REPORTING - Systems and methods regarding ventilation of a patient, such as a victim at the scene of an emergency are described herein. | 11-29-2012 |
20130296719 | RESCUE PERFORMANCE METRIC - A computer-implemented method for providing summary information for lifesaving activities is disclosed. | 11-07-2013 |
20140180138 | Ventilation Monitoring - According to an embodiment of the present invention, a ventilation monitoring device comprises at least one processor and at least one memory including computer program code. The at least one memory and the computer program code is configured with the at least one processor to cause the ventilation monitoring device to determine whether an intubated subject's tracheal tube is properly placed by receiving an indication of a subject's breath from at least one sensor. | 06-26-2014 |
20140213941 | Defibrillator Display Including CPR Depth Information - Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR) are described herein. | 07-31-2014 |
20140292534 | SYSTEM AND METHOD FOR WIRELESS AED DOCKING - According to an embodiment of the present invention, a system comprises a removable interface module and wireless dock for an automated external defibrillator. The removable interface module includes a first processor, a first memory and first low-power radio transceiver communicatively coupled with the first processor and configured to receive status information from the automated external defibrillator. The removable interface module further includes a wireless power receiver and a rechargeable energy storage device electrically coupled with the wireless power receiver and configured to receive power wirelessly for the removable interface module. The wireless dock includes a second processor, a second memory and second low-power radio transceiver communicatively coupled with the second processor and configured to receive the status information from the removable interface module when the automated external defibrillator is powered off and transmit the status information through a networking interface. The wireless dock further comprises a wireless power transmitter. | 10-02-2014 |
20140365175 | Rescue Performance Metrics for CPR and Traumatic Brain Injury - A computer-implemented method for providing summary information for lifesaving activities is disclosed. | 12-11-2014 |
20150018695 | Defibrillator Display - Systems and methods related to the field of cardiac resuscitation, and in particular to devices for assisting rescuers in performing cardio-pulmonary resuscitation (CPR) are described herein. | 01-15-2015 |
20150157816 | REPERFUSION PROTECTION IN RESUSCITATION - An apparatus and method for resuscitating a patient suffering from cardiac arrest or another condition in which normal circulation has been interrupted. A ventilator is used for delivering a gas mixture to the patient. The ventilator is configured to adjust the partial pressure of CO2 to one or more partial pressures high enough to slow expiration of CO2 from the patient's lungs and thereby maintain a reduced pH in the patient's tissues for a period of time following return of spontaneous circulation. | 06-11-2015 |
Patent application number | Description | Published |
20140201627 | EMS DECISION SUPPORT INTERFACE, EVENT HISTORY, AND RELATED TOOLS - Embodiments of the present invention include systems and methods for display and navigation of a clinical decision support process with portions thereof on separate display screens, as well as systems and methods for dynamically changing visual characteristics of softkeys on a patient monitor/defibrillator user interface screen based on clinical decision support or differential diagnosis processes, as well as a code review interface configured to permit a user to see what was displayed on a patient monitor/defibrillator user interface screen at any time during a medical event, as well as to see snapshots of other recorded parameters over the course of the medical event for purposes of code review, patient transfer, and improved patient care. | 07-17-2014 |
20140296675 | USE OF MUSCLE OXYGEN SATURATION AND PH IN CLINICAL DECISION SUPPORT - Embodiments of the present invention include a system having at least one sensor configured to monitor a muscle oxygen saturation (SmO2) level of a patient who is undergoing cardiac arrest and to generate a signal representing SmO2 level; a user interface device; a processor communicably coupled to the user interface device, the processor configured to cause the user interface device to present an array of two or more possible nodes of a clinical decision support tree, wherein at least one of the nodes indicates cardiopulmonary resuscitation (CPR) treatment of the patient with no ventilation, and wherein at least another of the nodes indicates CPR treatment of the patient with active ventilation; determine which of the two or more possible nodes should be emphasized based on the SmO2 level; and update the array of the two or more possible nodes based on the determination. | 10-02-2014 |
20150134297 | PHYSIOLOGICAL INPUT TO DETERMINE VALIDITY OF DATA - Systems and methods for determining validity of physiological data according to an embodiment of the present invention include a patient sensor configured to acquire patient data from a patient, wherein the patient data is physiological; and an environmental sensor configured to acquire environmental data related to validity of the patient data, wherein a value of the environmental data has a clinical effect on the validity of the patient data but not on performance of the environmental sensor; a control/monitoring system, wherein the control/monitoring system is configured to determine whether the environmental data satisfies one or more conditions indicative of the validity of the patient data and to flag the patient data that is invalid based on the determination. | 05-14-2015 |
Patent application number | Description | Published |
20110038455 | MONOCHROMATIC X-RAY METHODS AND APPARATUS - According to some aspects, an x-ray apparatus for imaging and/or radiation therapy is provided, the x-ray apparatus comprises an electron source capable of generating electrons, at least one first target arrange to receive electrons from the electron source, the at least one first target comprising material that, in response to being irradiated by the electrons, emits broad spectrum x-ray radiation, at least one second target arranged to receive at least some of the broad spectrum x-ray radiation, the at least one second target comprising material that, in response irradiation by broad spectrum x-ray radiation from the first target, emits monochromatic x-ray radiation, and at least one detector position to detect at least some of the monochromatic x-ray radiation emitted from the at least one second target. According to some aspects, a relatively low cost, relatively small footprint x-ray apparatus for generating monochromatic x-ray radiation suitable for medical/clinical purposes and appropriate for use in existing medical facilities such as hospitals and/or small clinical settings is provided. | 02-17-2011 |
20130188773 | MONOCHROMATIC X-RAY METHODS AND APPARATUS - According to some aspects, an x-ray apparatus for imaging and/or radiation therapy is provided, the x-ray apparatus comprises an electron source capable of generating electrons, at least one first target arranged to receive electrons from the electron source, the at least one first target comprising material that, in response to being irradiated by the electrons, emits broad spectrum x-ray radiation, at least one second target arranged to receive at least some of the broad spectrum x-ray radiation, the at least one second target comprising material that, in response to irradiation by broad spectrum x-ray radiation from the first target, emits monochromatic x-ray radiation, and at least one detector positioned to detect at least some of to the monochromatic x-ray radiation emitted from the at least one second target. According to some aspects, a relatively low cost, relatively small footprint x-ray apparatus for generating monochromatic x-ray radiation suitable for medical/clinical purposes and appropriate for use in existing medical facilities such as hospitals and/or small clinical settings is provided. | 07-25-2013 |
20130188778 | HYBRID X-RAY OPTIC APPARATUS AND METHODS - According to some aspects, a hybrid optic is provided. The hybrid optic comprises a capillary optic for receiving x-rays from an x-ray source at an entrance portion of the capillary optic and for providing x-rays at an exit portion of the capillary optic, and a grazing incidence multi-shell optic (GIMSO) coupled, at an entrance portion of the GIMSO, to the exit portion of the capillary optic to receive x-rays emerging from the exit portion of the capillary optic, the GIMSO including an exit portion for providing x-rays. | 07-25-2013 |
20150366526 | MONOCHROMATIC X-RAY METHODS AND APPARATUS - According to some aspects, an x-ray apparatus for imaging and/or radiation therapy is provided, the x-ray apparatus comprises an electron source capable of generating electrons, at least one first target arranged to receive electrons from the electron source, the at least one first target comprising material that, in response to being irradiated by the electrons, emits broad spectrum x-ray radiation, at least one second target arranged to receive at least some of the broad spectrum x-ray radiation, the at least one second target comprising material that, in response to irradiation by broad spectrum x-ray radiation from the first target, emits monochromatic x-ray radiation, and at least one detector positioned to detect at least some of the monochromatic x-ray radiation emitted from the at least one second target. According to some aspects, a relatively low cost, relatively small footprint x-ray apparatus for generating monochromatic x-ray radiation suitable for medical/clinical purposes and appropriate for use in existing medical facilities such as hospitals and/or small clinical settings is provided. | 12-24-2015 |
20150369758 | METHODS AND APPARATUS FOR DETERMINING INFORMATION REGARDING CHEMICAL COMPOSITION USING X-RAY RADIATION - According to some aspects, a method is provided comprising generating first monochromatic x-ray radiation at a first energy, directing at least some of the first monochromatic x-ray radiation to irradiate subject matter of interest, detecting at least some of the first monochromatic x-ray radiation transmitted through the subject matter of interest, and determining information about a chemical composition of the subject matter of interest based, at least in part, on the detected first monochromatic x-ray radiation and the first energy. | 12-24-2015 |
Patent application number | Description | Published |
20080296086 | DIAPHRAGM SURROUND - A surround for supporting a diaphragm used to create acoustic waves includes a rib section extending away from the diaphragm and a membrane section that is supported by the rib section. The membrane section has a thickness in a direction substantially normal to opposing top and bottom surfaces of the membrane section which is substantially thinner than a thickness of the rib section in a direction substantially normal to opposing top and bottom surfaces of the rib section. A restoring force returning the diaphragm to a home position is contributed to more due to deformation of the rib section than to deformation of the membrane section. | 12-04-2008 |
20090139794 | Diaphragm Surrounding - A surround for a diaphragm includes at least one rib section oriented to be extended during excursions of the diaphragm. The surround includes at least one membrane section supported by one or more rib sections contributing to a compliance characteristic different from the contribution of the one or more rib sections. | 06-04-2009 |
20100014702 | Resonating Cone Transducer - An electroacoustical transducer includes a bobbin, a first acoustic radiator coupled to the bobbin through a first surround having a mechanical compliance, a second acoustic radiator generally rigidly coupled to the bobbin, and a basket. The first acoustic radiator is coupled to the basket through a second surround, and the second acoustic radiator is coupled to the basket through a third surround. The first surround is constructed to cause the first acoustic radiator to move out of phase with the second acoustic radiator relative to the bobbin when actuated by the bobbin at acoustic frequencies at and above a resonant frequency of the first acoustic radiator. | 01-21-2010 |
20120043157 | THREE DIMENSIONAL ACOUSTIC PASSIVE RADIATING - A three dimensional acoustic passive radiator diaphragm. A diaphragm a three dimensional volume. An acoustic driver radiates pressure waves into the three dimensional volume to cause the diaphragm to expand and contract. The three dimensional passive radiator may include a core of a porous, compressible material. | 02-23-2012 |
20120160598 | ACOUSTIC DIAPHRAGM SUSPENDING - A suspension element for mechanically coupling an acoustic diaphragm to a stationary element. The suspension element is characterized by a total compliance. The total compliance includes a shear compliance and a beam compliance. The beam compliance is not significantly larger than the shear compliance. | 06-28-2012 |
20130306397 | Acoustic Diaphragm Suspending - A suspension element for mechanically coupling an acoustic diaphragm to a stationary element. The suspension element is characterized by a total compliance. The total compliance includes a shear compliance and a beam compliance. The beam compliance is not significantly larger than the shear compliance. | 11-21-2013 |
20140064522 | Speaker - A speaker includes a housing and four substantially similar electro-acoustic drivers secured inside the housing. The drivers are driven by substantially the same audio signal and are arranged such that the net mechanical vibrational force between the drivers and the housing is substantially zero. Four substantially similar passive radiators are secured inside the housing and driven by acoustic energy from the four drivers. The passive radiators are arranged such that the net mechanical vibrational force between the passive radiators and the housing is substantially zero. | 03-06-2014 |
Patent application number | Description | Published |
20120132521 | SYSTEMS AND DEVICES FOR TREATING WATER, WASTEWATER AND OTHER BIODEGRADABLE MATTER - The invention relates to bio-electrochemical systems for the generation of methane from organic material and for reducing chemical oxygen demand and nitrogenous waste through denitrification. The invention further relates to an electrode for use in, and a system for, the adaptive control of bio-electrochemical systems as well as a fuel cell. | 05-31-2012 |
20130075279 | MICROBIALLY-BASED SENSORS FOR ENVIRONMENTAL MONITORING - The present invention relates to the field of surface water monitoring. More specifically, the present invention provides low-cost, real-time bio-electrochemical sensors for surface water monitoring based on the metabolism of one or more electrogenic microbes. | 03-28-2013 |
20130112601 | DENITRIFICATION AND PH CONTROL USING BIO-ELECTROCHEMICAL SYSTEMS - The present invention provides reactor designs, component designs, and operating schemes for removing nitrates and chemical oxygen demand from any suitable wastewater stream. The invention also provides reactor designs, component designs, and operating schemes designed to modify and improve pH and water quality in wastewater streams. | 05-09-2013 |
20130299400 | BIO-ELECTROCHEMICAL SYSTEM FOR TREATING WASTEWATER - The invention relates to bio-electrochemical systems for treating wastewater, and sour gas produced by anaerobic digestion of organic material. The invention further relates to novel anode/cathode pairing schemes, and electric and hydraulic architectures for use in bio-electrochemical systems. | 11-14-2013 |
20140069806 | BIO-ELECTROCHEMICAL SYSTEMS - The present invention provides bio-electrochemical systems having various configurations for the treatment of water, wastewater, gases, and other biodegradable matter. In one aspect, the invention provides bio-electrochemical systems configured for treating wastewater while generating multiple outputs. In another aspect, the invention provides bio-electrochemical systems configured for improving the efficiency of electrodialysis removal systems. In yet another aspect, the invention provides bio-electrochemical systems configured for use in banks and basins. | 03-13-2014 |
20140353170 | BIOLOGICAL OXYGEN DEMAND SENSORS - Bioelectrochemical Systems (BES) for use as Biological Oxygen Demand (BOD) sensors, systems incorporating BES sensors for measuring BOD, and methods of using the sensors and systems for measuring BOD. The disclosed sensors are inexpensive to construct, long-lasting, have a fast response, and a large dynamic range. The invention includes biological oxygen demand (BOD) sensors which incorporate at least three working electrodes, at least one counter electrode, a reservoir for dilution fluid, and a sensor for measuring an electric current or a voltage which flows from the working electrodes to the counter electrode. The BOD sensors will typically also include at least one electrically active microbe disposed in proximity to the working electrode. | 12-04-2014 |
20150114904 | SYSTEM AND METHOD FOR WASTE TREATMENT - Systems and methods for treating multi-component waste streams. In general, systems and methods described herein employ a first chamber and a second chamber separated by a barrier and a filtration component that is fluidically connected to the first and second chambers. A waste stream to be treated will flow into the first chamber for treatment of the carbon-containing waste, then into the filtration component for the separation of the stream into a solid waste fraction and a liquid waste fraction. | 04-30-2015 |
20150147593 | Electrodes for Cost-Effective Bio-Electrochemical Systems - An electrode for use in bio-electrochemical systems is described, including: a substantially planar electrode material; a frame comprising a non-conductive substance; and one or more first conductive substances linked or secured to the frame. Bio-electrochemical systems, racks for inserting the electrode, and methods of using the racks are also described. | 05-28-2015 |
20150210575 | BIOLOGICAL TREATMENT SYSTEMS UTILIZING SELECTIVELY PERMEABLE BARRIERS - The invention includes a variety of systems that can be used to remove contaminants from a fluidic medium, typically an aqueous medium. In an embodiment, the systems contain treatment zones including a semi-permeable barrier constructed to segregate cultures of microorganisms that metabolize the contaminants from the media. The semi-permeable barriers allow the contaminants to be exchanged between the medium and the culture, however the culture is kept away from the media. With time, the microorganisms consume the contaminants and the medium is cleaned. In some embodiments, the system additionally includes electrodes and uses exoelectrogenic microorganisms to remove contaminants. | 07-30-2015 |
20150300982 | Microbially-Based Sensors for Environmental Monitoring - The present invention relates to the field of surface water monitoring. More specifically, the present invention provides low-cost, real-time bio-electrochemical sensors for surface water monitoring based on the metabolism of one or more electrogenic microbes. | 10-22-2015 |
Patent application number | Description | Published |
20090325176 | Gene Expression Profiles Associated with Asthma Exacerbation Attacks - The present invention provides methods for the assessment, diagnosis, or prognosis of asthma exacerbation, by assessing the level of expression of asthma exacerbation gene products in a sample derived from a patient. The markers of the present invention can be used in methods to identify or evaluate agents capable of modulating marker expression levels in subjects with asthma. | 12-31-2009 |
20120101108 | Anaplastic Lymphoma Kinase In Kidney Cancer - The invention provides methods to identify, diagnose, and treat kidney cancer through the detection of expression and/or activity of anaplastic lymphoma kinase (ALK). The detection of the presence of a polypeptide with ALK kinase activity (e.g., by detecting expression and/or activity of the polypeptide), identify those kidney cancers that are likely to respond to an ALK-inhibiting therapeutic. | 04-26-2012 |
20150056193 | EGFR AND ROS1 KINASE IN CANCER - The present disclosure provides methods of that include detecting in a biological sample from a patient having or suspected of having cancer the presence of a polypeptide having ROS1 kinase activity or a polynucleotide encoding the same and detecting in the biological sample the presence of a mutant EGFR polypeptide or a polynucleotide encoding the same. In some aspects, the disclosure provides methods of treating a patient for cancer that include determining that a biological sample from a tumor in the patient includes a polypeptide having ROS1 kinase activity or a polynucleotide encoding the same and a mutant EGFR polypeptide or a polynucleotide encoding the same and administering to the patient a therapeutically effective amount of a ROS1 inhibitor and an EGFR inhibitor, thereby treating the patient for cancer. | 02-26-2015 |
20150369810 | ANAPLASTIC LYMPHOMA KINASE IN KIDNEY CANCER - The invention provides methods to identify, diagnose, and treat kidney cancer through the detection of expression and/or activity of anaplastic lymphoma kinase (ALK). The detection of the presence of a polypeptide with ALK kinase activity (e.g., by detecting expression and/or activity of the polypeptide), identify those kidney cancers that are likely to respond to an ALK-inhibiting therapeutic. | 12-24-2015 |
Patent application number | Description | Published |
20130296231 | CHARGED NUTRITIVE PROTEINS AND METHODS - Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in a benchmark protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in a benchmark protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 11-07-2013 |
20140212541 | Charged Nutritive Proteins and Methods - Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in a benchmark protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in a benchmark protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 07-31-2014 |
20140342978 | Charged Nutritive Proteins and Methods - Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in a benchmark protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in a benchmark protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 11-20-2014 |
20150011482 | Nutritive Fragments, Proteins and Methods - Nutritive proteins are provided. In some embodiments the nutritive proteins comprise a first polypeptide sequence comprising a fragment of a naturally-occurring nutritive protein. In some embodiments the fragment comprises at least one of a) an enhanced ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein; b) an enhanced ratio of leucine residues to total amino acid residues present in the nutritive protein; and c) an enhanced ratio of essential amino acid residues to total amino acid residues present in the nutritive protein. In some embodiments, the fragment comprises at least one of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein, that is equal to or greater than the corresponding ratio present in a benchmark protein such as whey, egg or soy protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 01-08-2015 |
20150080296 | Nutritive Fragments, Proteins and Methods - Nutritive proteins are provided. In some embodiments the nutritive proteins comprise a protein digestibility corrected amino acid score (PDCAAS) that exceeds a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 03-19-2015 |
20150087602 | Nutritive Proteins and Methods - Nutritive proteins are provided. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in whey protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in whey protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in whey protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 03-26-2015 |
20150093495 | Nucleic Acids, Cells, and Methods for Producing Secreted Proteins - A method for producing a secreted recombinant polypeptide sequence is provided. In some embodiments it comprises providing a recombinant microorganism comprising a recombinant nucleic acid comprising a first nucleic acid sequence encoding the recombinant polypeptide sequence operatively linked to a second nucleic acid sequence encoding a signal peptide; and culturing the recombinant microorganism in a culture medium under conditions sufficient for production and secretion of the recombinant protein by the recombinant microorganism. In some embodiments the coding sequence for the signal peptide is not native to the recombinant microorganism. In some embodiments the recombinant microorganism is photo synthetic. Also provided are recombinant photosynthetic microorganisms, isolated polypeptides comprising a signal peptide comprising an amino acid sequence disclosed herein, and isolated nucleic acids comprising a coding sequence for one of the signal peptides, among other things. | 04-02-2015 |
20150126441 | Nutritive Fragments and Proteins with Low or No Phenylalanine and Methods - Nutritive proteins comprising no phenylalanine (Phe) are provided. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in a benchmark protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in a benchmark protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. The compositions are useful, for example, to provide protein in the diet of subjects with a disorder characterized by accumulation of Phe in the body. | 05-07-2015 |
20150232520 | Charged Nutritive Fragments, Proteins and Methods - Charged nutritive proteins provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in a benchmark protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in a benchmark protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in a benchmark protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things. | 08-20-2015 |
20150307562 | ENGINEERED SECRETED PROTEINS AND METHODS - Nutritive proteins are provided herein. Also provided are various other embodiments including nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, vectors for expressing the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins. Nutritive proteins include engineered proteins, wherein the engineered proteins comprise a sequence of at least 20 amino acids that comprise an altered amino acid sequence compared to the amino acid sequence of a reference secreted protein and a ratio of essential amino acids to total amino acids present in the engineered protein higher than the ratio of essential amino acids to total amino acids present in the reference secreted protein. In some embodiments, the engineered protein comprises at least one essential amino acid residue substitution of a non-essential amino acid residue in the reference secreted protein. | 10-29-2015 |
Patent application number | Description | Published |
20080309920 | Method and System for Optoelectronic Detection and Location of Objects - Disclosed are methods and systems for optoelectronic detection and location of moving objects. The disclosed methods and systems capture one-dimensional images of a field of view through which objects may be moving, make measurements in those images, select from among those measurements those that are likely to correspond to objects in the field of view, make decisions responsive to various characteristics of the objects, and produce signals that indicate those decisions. The disclosed methods and systems provide excellent object discrimination, electronic setting of a reference point, no latency, high repeatability, and other advantages that will be apparent to one of ordinary skill in the art. | 12-18-2008 |
20080310676 | Method and System for Optoelectronic Detection and Location of Objects - Disclosed are methods and systems for optoelectronic detection and location of moving objects. The disclosed methods and systems capture one-dimensional images of a field of view through which objects may be moving, make measurements in those images, select from among those measurements those that are likely to correspond to objects in the field of view, make decisions responsive to various characteristics of the objects, and produce signals that indicate those decisions. The disclosed methods and systems provide excellent object discrimination, electronic setting of a reference point, no latency, high repeatability, and other advantages that will be apparent to one of ordinary skill in the art. | 12-18-2008 |
20090257621 | Method and System for Dynamic Feature Detection - Disclosed are methods and systems for dynamic feature detection of physical features of objects in the field of view of a sensor. Dynamic feature detection substantially reduces the effects of accidental alignment of physical features with the pixel grid of a digital image by using the relative motion of objects or material in and/or through the field of view to capture and process a plurality of images that correspond to a plurality of alignments. Estimates of the position, weight, and other attributes of a feature are based on an analysis of the appearance of the feature as it moves in the field of view and appears at a plurality of pixel grid alignments. The resulting reliability and accuracy is superior to prior art static feature detection systems and methods. | 10-15-2009 |
20090273668 | METHOD FOR SETTING PARAMETERS OF A VISION DETECTOR USING PRODUCTION LINE INFORMATION - Disclosed are systems and methods for setting various operating parameters of a vision detector from production line information that can be supplied by a manufacturing technician who is not skilled in the art of the invention. These operating parameters include shutter time, video gain, idle time, frame count, and locator search range. The production line information includes line speed, field of view size, direction of motion, and object spacing. | 11-05-2009 |
20100199475 | System and method for utilizing a linear sensor - Systems and methods for utilizing linear optoelectronic sensors are provided. A plurality of linear sensors may be utilized to obtain velocity measurements of a web material at two points. The acceleration of the web material may be determined from the velocity measurements and a control signal issued to a servo to maintain proper tension along the web material. | 08-12-2010 |
20110063459 | SYSTEM AND METHOD FOR ACQUIRING A STILL IMAGE FROM A MOVING IMAGE - This invention provides a system and method captures a moving image of a scene that can be more readily de-blurred as compared to images captured through the above-referenced and other known methods operating on an equivalent exposure-time interval. Rather than stopping and starting the integration of light measurement during the exposure-time interval, photo-generated current is switched between multiple charge storage sites in accordance with a temporal switching pattern that optimizes the conditioning of the solution to the inverse blur transform. By switching the image intensity signal between storage sites all of the light energy available during the exposure-time interval is transduced to electronic charge and captured to form a temporally decomposed representation of the moving image. As compared to related methods that discard approximately half of the image intensity signal available over an equivalent exposure-time interval, such a temporally decomposed image is a far more complete representation of the moving image and more effectively de-blurred using simple linear de-convolution techniques. | 03-17-2011 |