Patent application number | Description | Published |
20080206104 | Accurate Magnetic Biosensor - The invention provides a method, a device and a system for determining the concentration of at least one sort of targets in a fluid containing at least one sort of polarizable of polarized magnetic labels in a fluid, the sensing surface comprising at least one sort of binding sites capable to specifically attach to at least one sort of biological entities linked to the magnetic labels, the sensing device further comprising at least one magnetic sensor element, the sensing device further comprising distinction means for time-resolved distinguishing between magnetic labels specifically attached to the binding sites versus labels non-specifically attached. The method and device according to the present invention may be applied to biomolecular diagnostics. | 08-28-2008 |
20080207464 | Amplification of Nucleric Acids with Magnetic Detection - The present invention describes a method of amplifying nucleic acids and determining the amount of amplified nucleic acids using magnetic detection. The detection can be performed during the amplification process of the nucleic acid. During the detection, the amplified nucleic acid is bound to a sensor via a biological molecule. | 08-28-2008 |
20080211090 | Packed Semiconductor Sensor Chip For Use In Liquids - The present invention provides a packed semiconductor sensor chip ( | 09-04-2008 |
20080247910 | Device for Testing a Fluid | 10-09-2008 |
20080268481 | Sensitive Magnetic Catch Assay By Building a Strong Binding Couple - The invention relates to a sensor device for detecting a target in a sample suspected of comprising the target, which device is suitable for use in an assay such as a sandwich assay. The invention further relates to a method for detecting a target in a sample. The device comprises a sensor surface, which is functionalised with one moiety of a strong binding couple, which moiety preferably shows little or no cross reactivity with the target molecule. | 10-30-2008 |
20080309329 | On-Chip Magnetic Sensor Device with Suppressed Cross-Talk - A magnetic sensor device is disclosed for the detection or determination of a magnetic field, such as for example, but not limited to, the presence of magnetic particles ( | 12-18-2008 |
20080311598 | Magnetic Biosensor For Determination of Enzymic Activity - Magnetic sensors are very suitable for use in determination of enzymatic activity. In a preferred embodiment the invention relates to a method for determining activity of an enzyme in modification of substrate ( | 12-18-2008 |
20090008064 | Cooling System for Electronic Substrates - The present invention relates to a cooling system for an electronic substrate comprising a heat transfer fluid ( | 01-08-2009 |
20090141335 | Display device - Display device is based on layer break up or layer displacement having at least two different states, in which one of the fluids, e.g., oil in a first state, adjoins at least a first support plate and, in the second state, the other fluid at least partly adjoins the first support plate. In one embodiment, a picture element corresponds to a substantially closed space and, in the first state, the other fluid layer substantially completely adjoins both support plates and is divided in two sub-layers. This makes it possible, on the one hand, to use lower voltages to make displacement occur. On the other hand, this opens the opportunity to color displays. | 06-04-2009 |
20090170212 | RAPID MAGNETIC BIOSENSOR - The present invention relates to methods and (bio)sensor systems. Herein, magnetic fields are applied in order to transport magnetic particles laterally over a sensor surface with analyte specific probes. The methods of the invention allow the specific binding of magnetic particles to the sensor surface, while aspecific and unbound particles are removed. | 07-02-2009 |
20100009456 | FAST BIOSENSOR WITH REAGENT LAYER - A detection system ( | 01-14-2010 |
20100033158 | MEASURING AGGLUTINATION PARAMETERS - A method and system are described for measuring agglutination in a target-induced agglutination assay with one or more magnetic particles performed in a reaction chamber. After the magnetic particles ( | 02-11-2010 |
20100045267 | MAGNETIC AND/OR ELECTRIC LABEL ASSISTED DETECTION SYSTEM AND METHOD - A detection system ( | 02-25-2010 |
20100109653 | SENSOR DEVICE FOR AND A METHOD OF SENSING PARTICLES - A sensor device ( | 05-06-2010 |
20100132797 | MICROFLUIDIC SYSTEM BASED ON ACTUATOR ELEMENTS - The present invention provides a microfluidic system comprising at least one microchannel ( | 06-03-2010 |
20100173290 | MONITORING OF ENZYMATIC PROCESSES BY USING MAGNETIZABLE OR MAGNETIC OBJECTS AS LABELS - The present invention provides a method and device for monitoring an enzymatic process of a biological molecule by, at least once, during the enzymatic process determining an amount of magnetic particles attached to a sensor surface. The method and device according to embodiments of the present invention may be used for monitoring an enzymatic process as a function of time. | 07-08-2010 |
20100194386 | MAGNETIC SENSOR DEVICE - The present invention provides a sensor device ( | 08-05-2010 |
20100273142 | MULTI-COMPARTMENT DEVICE WITH MAGNETIC PARTICLES - The present invention discloses microfluidic devices with a valve-like structure (3), through which magnetic particles can be transported with minimal transport of fluids. This allows sequential processing of the magnetic particles. | 10-28-2010 |
20100289483 | SENSOR CARTRIDGE - The present invention provides a sensor cartridge ( | 11-18-2010 |
20110116153 | DISPLAY DEVICE - Display device is based on layer break up or layer displacement having at least two different states, in which one of the fluids, e.g., oil in a first state, adjoins at least a first support plate and, in the second state, the other fluid at least partly adjoins the first support plate. In one embodiment, a picture element corresponds to a substantially closed space and, in the first state, the other fluid layer substantially completely adjoins both support plates and is divided in two sub-layers. This makes it possible, on the one hand, to use lower voltages to make displacement occur. On the other hand, this opens the opportunity to color displays. | 05-19-2011 |
20110171086 | MICROFLUIDIC DEVICE - A microfluidic device is provided, the microfluidic device comprising: a plurality of chambers ( | 07-14-2011 |
20120126154 | VALVE WITH MATERIAL HAVING MODIFIABLE DEGREE OF PENETRABILITY - The invention relates to a valve ( | 05-24-2012 |
20120161754 | APPARATUS FOR THE ENRICHMENT OF MAGNETIC PARTICLES - The invention relates to a method and an apparatus ( | 06-28-2012 |
20130095495 | MULTI EPITOPE ASSAY - The present invention is related to a method for detection of a biological target in an affinity assay, the method comprising the steps of providing a biological sample volume containing the biological target, adding a first capturing moiety to the biological sample volume comprising the biological target, wherein the first capturing moiety is adhered to a particle, concentration of the captured biological target into an elution volume that is smaller than the biological sample volume in step a), cleavage of the first capturing moiety or the biological target from the particle and direct or indirect detection and/or quantification of the biological target in a sandwich or competitive affinity assay format, wherein the biological target is associated with at least one capturing moiety, preferably at least two capturing moieties. | 04-18-2013 |
20130109106 | SYSTEM FOR SELECTIVELY PROCEEDING A SAMPLE | 05-02-2013 |
20140127722 | MOLECULAR ARCHITECTURE ON MAGNETIC PARTICLES FOR AFFINITY ASSAYS WITH LOW NON-SPECIFIC BINDING - The present invention relates to a coating for preventing non-specific binding of molecules to a surface layer comprising an affinity molecule, said coating comprises single layer comprising non-affine spacer molecules forming a mesh; or a shell structure, wherein said shell structure comprises a first layer comprising one or more affinity molecules and further a second layer, which is coupled to the first layer, and wherein said first and second layer comprise non-affine spacer molecules forming a mesh. The present invention further relates to a particle, a flat structure or a matrix comprising such a coating. In a further aspect the present invention relates to the use of the coating, coated particle, coated flat structure or coated matrix for detection and/or purification of a specific target biomolecule from a sample and/or determination of the concentration of the specific target biomolecule. The present invention further relates to an assay for the detection of specific target biomolecules from a sample and/or determination of the concentration of specific target biomolecules comprising the use of such coating, coated particle, coated flat structure or coated matrix, in particular coated nanoparticles. | 05-08-2014 |