Smith, London
Adrian Maxwell Smith, London GB
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20090196401 | Machine vision system - A fluorescing marker is used in order to mark (for example) a leaf of a multi-leaf collimator and/or the reference points within the field of view. The markers are illuminated with light tuned to cause the markers to fluoresce at a wavelength different to that of the illuminating light. The fluorescence is then detected by a camera. This method allows the image to be captured by the camera with increased contrast. Accordingly, the present invention provides a multi-leaf collimator for a radiotherapeutic apparatus, comprising at least one leaf having a fluorescent marker. The fluorescent marker will usually emit light of a wavelength longer than the incident light, allowing suitable filters to be provided in order to distinguish the light emitted by the markers. A suitable material for use in the fluorescent markers is ruby. The present invention also provides a radiotherapeutic apparatus comprising a multi-leaf collimator as defined above, and a camera arranged to view the fluorescent markers. A source of illumination for the fluorescent markers is ideally monochromatic, or nearly so. The camera can have a filter arranged to substantially prevent light of the wavelength emitted by the source of illumination from entering the camera, thereby improving the contrast of the image. The radiotherapeutic apparatus can also comprise a source of illumination that is optically co-located with a radiation source, to allow the radiation field that will be emitted to be checked visually by an operator. The co-located source is preferably substantially monochromatic, emitting substantially no light at the wavelength of the fluorescent markers. A filter can then be placed over an output of the radiotherapeutic apparatus, for blocking light of the wavelength of the fluorescent markers and thereby enhancing the contrast of the image that is taken of the fluorescent markers. | 08-06-2009 |
20110049396 | Multi-Leaf Collimators - A multi-leaf collimator for a radiotherapy apparatus comprises a plurality of elongate leaves mounted in a carriage, the carriage being mounted on a substrate, wherein the leaves are independently moveable relative to the carriage in a longitudinal direction, and the carriage is moveable in that direction relative to the substrate, and a control apparatus arranged to receive a signal representing leaf positions relative to the substrate and being arranged to control the leaf positions relative to the carriage and the carriage positions relative to the substrate so as to achieve those leaf positions relative to the substrate. By allowing the carriage to be driven concurrently with the leaves, the speed of movement of the carriage can be added to that of the leaves. In this way, where leaves are required to make a long traverse they can do so more quickly. Most MLCs have a means for sensing the current positions of the leaves relative to the substrate, such as an optical or mechanical positional feedback system. The control apparatus can therefore compare the current leaf positions to the signalled leaf positions, and move the leaves and the carriage accordingly. Each leaf can be moved according to a difference between the current leaf position and the signalled leaf position, and the carriage can be moved according to an average difference between the current leaf positions and the signalled leaf positions. A corresponding method is also disclosed. | 03-03-2011 |
20120215051 | Radiotherapeutic Apparatus - The ability to provide a fine resolution variation in the dose rate of radiotherapeutic apparatus would allow delivery times of VMAT and related techniques to be reduced significantly. A radiotherapeutic apparatus is described, comprising a source of radiation able to issue pulses of radiation at a base frequency, and a control apparatus arranged to permit pulses provided these match a pulse pattern chosen to achieve a selected time-averaged power level, the chosen pulse pattern being one selected from a plurality of pulse patterns that include patterns consisting of trains of pulses that include, relative to the base frequency, at least every n | 08-23-2012 |
Alan P. Smith, London GB
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20130182573 | MULTI-CLASS DATA TRANSPORT - Methods and apparatus for controlling the forwarding of a flow ( | 07-18-2013 |
Andrew J. Smith, London GB
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20140063048 | VISUAL ACCESSIBILITY INDICATORS - Systems and methods are described for providing visual accessibility indicators on mobile devices. A computerized method of presenting a visual accessibility indicator relating to a target file includes detecting, using a mobile device, an active network connection of the mobile device to be used to transfer the target file, retrieving a connection profile for the active network connection, the connection profile including attributes relating to the active network connection, projecting accessibility of the target file at least partially based on the connection profile, and displaying, on the mobile device, a visual accessibility indicator representing the projected accessibility, wherein the visual accessibility indicator contains an icon illustrating the accessibility. | 03-06-2014 |
Brian D. Smith, London GB
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20090236439 | DISPERSING FRAGRANCES - A fragrance disperser in one form includes a single fan that passes air over a wicked single or double fragrance. A second form has the fan reversible to provide two different airstreams that evaporate respective different fragrances one after the other. Where two fragrances are provided, the evaporation may be by respective electrical heaters. A fragrance source may be formed by two sheets joined together to form two chambers each receiving a respective wick and having respective exposed wick portions. The source may incorporate a source of electrical power. An alternative source has a reservoir for fragrance and a wick located in an air passage forming part of the source so that an air flow is guided through the passage past the wick to evaporate fragrance. Where two fragrances are provided, the fragrance sources may be located side-by-side and matching fragrances may have, for example, matching indicia on the sources so that the match can be easily determined visually. | 09-24-2009 |
20100038443 | DISPERSING FRAGRANCES - A fragrance disperser in one form includes a single fan that passes air over a wicked single or double fragrance. A second form has the fan reversible to provide two different airstreams that evaporate respective different fragrances one after the other. Where two fragrances are provided, the evaporation may be by respective electrical heaters. A fragrance source may be formed by two sheets joined together to form two chambers each receiving a respective wick and having respective exposed wick portions. The source may incorporate a source of electrical power. An alternative source has a reservoir for fragrance and a wick located in an air passage forming part of the source so that an air flow is guided through the passage past the wick to evaporate fragrance. Where two fragrances are provided, the fragrance sources may be located side-by-side and matching fragrances may have, for example, matching indicia on the sources so that the match can be easily determined visually. | 02-18-2010 |
20100163639 | DISPERSING FRAGRANCES - A fragrance disperser in one form includes a single fan that passes air over a wicked single or double fragrance. A second form has the fan reversible to provide two different airstreams that evaporate respective different fragrances one after the other. Where two fragrances are provided, the evaporation may be by respective electrical heaters. A fragrance source may be formed by two sheets joined together to form two chambers each receiving a respective wick and having respective exposed wick portions. The source may incorporate a source of electrical power. An alternative source has a reservoir for fragrance and a wick located in an air passage forming part of the source so that an air flow is guided through the passage past the wick to evaporate fragrance. Where two fragrances are provided, the fragrance sources may be located side-by-side and matching fragrances may have, for example, matching indicia on the sources so that the match can be easily determined visually. | 07-01-2010 |
Daniel Charles Smith, London GB
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20150294072 | DEVICES, SYSTEMS AND METHODS FOR SUPPORTING A VETERINARY PRACTICE - Systems and techniques for supporting a veterinary practice are provided. Further, systems and techniques for the collection and display of animal wellness information are provided. Animal wellness data relating to a single animal patient or group of animal patients are collected and subsequently displayed at a desired remote location or on a mobile device so that a veterinarian can review the information. | 10-15-2015 |
Eden Richard Smith, London GB
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20120116259 | BELT FOR TRAINING ABDOMINAL MUSCLES AND TRAINING METHOD EMPLOYING THE SAME - A belt for training abdominal muscles comprises means ( | 05-10-2012 |
Frank Martin Smith, London GB
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20100017320 | DATA FLOWS IN A COMPUTER OPERATED CURRENCY TRADING SYSTEM - In a computer implemented currency trading support system trades are provided to a third party ( | 01-21-2010 |
Fraser Smith, London GB
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20120170731 | METHOD FOR RE-CONFIGURING A COMMUNICATIONS DEVICE - A communications device ( | 07-05-2012 |
20120195412 | METHOD OF RETRIEVING SERVICE INFORMATION - A method for a communications device ( | 08-02-2012 |
20120220268 | METHOD OF CONFIGURING A DEVICE FOR COMMUNICATIONS SERVICE ACTIVATION - A method of generating device-specific configuration data during the initial set up of a device ( | 08-30-2012 |
Geoffrey Smith, London GB
Patent application number | Description | Published |
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20090110694 | Anti-Inflammatory Proteins and Improved Vaccines - A recombinant poxvirus lacking a functional gene corresponding to BI4R in the WR strain of VACV for use as a medicament especially as a vaccine against a disease caused by a poxvirus or another pathogenic agent or for use as a medicament against a disease associated with aberrant cells. An isolated nucleotide or polypeptide encoding a poxvirus sequence corresponding to the sequence of B14 in the WR strain of VACV especially for use as a medicament against undesirable inflammation, immune activation or NF-κB activation. Related compositions and methods. | 04-30-2009 |
20100016224 | COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE - The present invention relates to a method of enhancing a pro-inflammatory immune response through the administration of the DEAD-box protein DDX3, as encoded by SEQ ID NO:1. The invention further extends to a method of suppressing an aberrant immune response, such at that associated with autoimmune conditions, through inhibition of DDX3. The invention also extends to a method of suppressing a pro-inflammatory immune response through the administration of the vaccinia virus protein K7. The invention further extends to the provision of an attenuated poxvirus wherein the K7R gene which encodes for the K7 protein is deleted or rendered non-functional. Pharmaceutical compositions comprising DDX3 inhibitory compounds, such as K7, are also provided. | 01-21-2010 |
Geoffrey C. Smith, London GB
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20140058775 | METHODS AND SYSTEMS FOR MANAGING SUPPLY CHAIN PROCESSES AND INTELLIGENCE - A Global Supply Chain Intelligence system (“GSCI”) adapted to predict, discover and verify commodity trade flows. Creating and maintaining a dataset that tracks real and near real-time commodity flows as they happen as an input to the GSCI. The dataset used in a business intelligence process within the GSCI to arrive at an output, such as a predicted price behavior, a price alert, a risk alert, etc. A Commodity Flow Intelligence (CFI) component that collects and analyzes information with the timeliness, detail and accuracy required to track, forecast and predict supply and demand imbalances at the discrete flow level to aid market participants in making operational trading and investment decisions, for example, in connection with a financial services system or offering providing enhanced data and tools to promote market transparency. | 02-27-2014 |
Graham Smith, London GB
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20110195024 | ISATIN DERIVATIVES FOR USE AS IN VIVO IMAGING AGENTS - Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed. | 08-11-2011 |
20110236312 | NUCLEOSIDE ANALOGUES USEFUL AS POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS - The invention provides compounds that comprise a 4′-thio nucleoside that is a derivative of 4′-thiothymidine or 4′-thio-2′-deoxyuridine comprising a positron or single photon emitting radioisotope or corresponding non-radioactive isotope attached via a triazole link to the N-3 position. Methods for preparing such compounds and uses of the compounds in medicine are also provided. | 09-29-2011 |
20130178653 | NOVEL PRECURSOR OF RADIOLABELLED CHOLINE ANALOG COMPOUNDS - The present invention describes intermediate(s), pre-cursor(s), for the preparation of radialabelled choline analogs to be used as radiotracers for Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) imaging of diseases. | 07-11-2013 |
20130183239 | ISOTOPIC CARBON CHOLINE ANALOGS - Novel choline-derived radiotracer (s) having an isotopic carbon for Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) imaging of disease states related to altered choline metabolism (e.g., tumor imaging of prostate, breast, brain, esophageal, ovarian, endometrial, lung and prostate cancer—primary tumor, nodal disease or metastases). | 07-18-2013 |
20130202530 | NOVEL RADIOTRACER - Novel radiotracer(s) for Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) imaging of disease states related to altered choline metabolism (e.g., tumor imaging of prostate, breast, brain, esophageal, ovarian, endometrial, lung and prostate cancer—primary tumor, nodal disease or metastases). The present invention also describes intermediate(s), pre-cursor(s), pharmaceutical composition(s), methods of making, and methods of use of the novel radiotracer(s). | 08-08-2013 |
Ian Christopher Smith, London GB
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20100029624 | Male Contraceptive - A compound having formula I. R | 02-04-2010 |
Ian Kenneth Smith, London GB
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20090188253 | Expander Lubrication in Vapour Power Systems - A vapour power generating system for generating power by using heat from a source of heat. The system has a closed circuit for a working fluid, and includes a heat exchanger assembly ( | 07-30-2009 |
20110048009 | GENERATING POWER FROM MEDIUM TEMPERATURE HEAT SOURCES - A method, and associated apparatus, for generating power from medium temperature heat sources in the range of 200° to 700° C. with improved efficiency compared to systems operating on a Rankine cycle in which the working fluid is condensed at the same temperature. Water is heated in a boiler ( | 03-03-2011 |
20120312009 | EXPANDER LUBRICATION IN VAPOUR POWER SYSTEMS - A vapour power generating system including a closed circuit for a working fluid, and includes a heat exchanger assembly for heating the fluid under pressure with heat from the source, a separator for separating the vapour phase of the heated fluid from the liquid phase thereof, an expander for expanding the vapour to generate power, a condenser for condensing the outlet fluid from the expander, a feed pump for returning condensed fluid from the condenser to the heater and a return path for returning the liquid phase from the separator to the heater. The liquid phase of the working fluid contains a lubricant which lubricant is soluble or miscible in the liquid phase and a bearing supply path is arranged to deliver liquid phase pressurised by the feed pump to at least one bearing for a rotary element of the expander. | 12-13-2012 |
20130052072 | LUBRICATION OF SCREW MACHINES - A screw machine for use with a working fluid with a liquid phase present comprises rotors having meshed, lubricated helical formations. The rotors have an ‘N’ profile as disclosed in WO 97/43550. In use, lubrication of the helical formations of the rotors and optionally of the rotor bearings is achieved substantially exclusively with the liquid phase of the working fluid. | 02-28-2013 |
Jasper Smith, London GB
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20140302921 | GAMES SYSTEM - A games system includes a handheld games controller ( | 10-09-2014 |
Jeremy Nicholas Smith, London GB
Patent application number | Description | Published |
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20120058597 | FABRICATION METHOD FOR THIN-FILM FIELD-EFFECT TRANSISTORS - A thin-film field-effect transistor is formed by forming a dielectric layer adjacent a gate, forming a source region and a drain region, and forming a semiconductor layer on the dielectric layer. The semiconductor layer is deposited by spray pyrolysis and comprises a material selected from a group comprising: oxides; oxide-based materials; mixed oxides; metallic type oxides; group I-IV, II-VI, III-VI, IV-VI, V-VI and VIII-VI binary chalcogenides; and group I-II-VI, II-II-VI, II-III-VI, II-VI-VI and V-II-VI ternary chalcogenides. | 03-08-2012 |
Jeremy S. Smith, London GB
Patent application number | Description | Published |
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20090327039 | Network based procurement and sourcing method - A method for enhancing the procurement processes and sourcing strategy options of an organization, including registering purchase item data, supply item data, demand market data, and supply market data, and generating one or more suggested procurement and sourcing strategies using a power and leverage positioning methodology. The method provides a recommended level of analysis with respect to the criticality of the purchase items to generate suggested procurement and sourcing strategies. A method for developing the competence of the staff of an organization in the management of a procurement process, having a plurality of steps for the selection of procurement and sourcing strategies pre-contractually and for managing supplier performance post-contractually is also disclosed. | 12-31-2009 |
John Smith, London GB
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20110210728 | ENHANCING SIGNALS - A method of testing a sample comprising the steps of: applying an excitation to the sample; detecting a response signal from the sample; processing a first part and a second part of the response signal; and determining from the second part of the response signal information with which to enhance the first part of the response signal. | 09-01-2011 |
John Alec Sidney Smith, London GB
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20080309339 | System and Method for Improving the Analysis of Chemical Substances Using Nqr - A method for analysing a chemical substance containing quadrupolar nuclei to determine a measurable characteristic of the substance. The method includes irradiating the substance with RF energy in a prescribed manner to stimulate NQR of certain quadrupolar nuclei within the substance. Then receiving and processing a signal emitted from the substance to isolate an NQR signal therefrom. Thereafter analysing the NQR signal to obtain a measure of the characteristic of the substance; and providing an output indicative of the measure for analytical purposes. Specific methods for analysing a chemical substance during production thereof to determine a characteristic of the substance indicative of the quality thereof, and for searching for chemicals together with specific systems are also described. | 12-18-2008 |
20120068701 | System and Method for Improving the Analysis of Chemical Substances Using NQR - The present application discloses systems and methods for analyzing a chemical substance containing quadrupolar nuclei to determine a measurable characteristic of the substance. The systems and methods include irradiating the substance with RF energy to stimulate NQR of certain quadrupolar nuclei within the substance, receiving and processing a signal emitted from the substance to isolate an NQR signal therefrom, analyzing the NQR signal to obtain a measure of the characteristic of the substance, and providing an output indicative of the measure for analytical purposes. | 03-22-2012 |
Jonathan Smith, London GB
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20110252437 | ENTERTAINMENT APPARATUS - A video pod comprises side wails and a roof; a first display device inside the video pod; a second display outside and above en opening to the pod; a payment device; an input device; and a memory storing a plurality of video programs. The first display device is arranged to display a selected one of said video programs upon payment via the payment device and selection via the input device by a user, and the second display device is arranged to display a promotional video different to the video programs. | 10-13-2011 |
20140244134 | THROTTLE BEHAVIOUR - A controller for controlling a power source in response to a throttle input, the throttle input representing the status of a throttle control in a range from a minimum state to a maximum state, the controller being configured to control the power source in dependence on both the current status of the throttle control and the current direction of change of that status between the maximum state and the minimum state. | 08-28-2014 |
Karl Smith, London GB
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20160055335 | METHOD AND APPARATUS FOR DETECTING A MULTI-STAGE EVENT - A multi-stage event detector for monitoring a system to detect the occurrence of multistage events in the monitored system, the multi-stage event detector includes: one or more event detecting detector units ( | 02-25-2016 |
Kate Smith, London GB
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20110252437 | ENTERTAINMENT APPARATUS - A video pod comprises side wails and a roof; a first display device inside the video pod; a second display outside and above en opening to the pod; a payment device; an input device; and a memory storing a plurality of video programs. The first display device is arranged to display a selected one of said video programs upon payment via the payment device and selection via the input device by a user, and the second display device is arranged to display a promotional video different to the video programs. | 10-13-2011 |
Kate L. Smith, London GB
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20100155496 | ELECTROSTATIC SPRAYING DEVICE AND A METHOD OF ELECTROSTATIC SPRAYING - An electrostatic spraying device ( | 06-24-2010 |
Kenneth W.d. Smith, London GB
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20140029733 | METHOD AND APPARATUS FOR TONE DETECTION - A speech server and methods provide audio stream analysis for tone detection in addition to speech recognition to implement an accurate and efficient answering machine detection strategy. By performing both tone detection and speech recognition in a single component, such as the speech server, the number of components for digital signal processing may be reduced. The speech server communicates tone events detected at the telephony level and enables voice applications to detect tone events consistently and provide consistent support and accuracy of both inbound and outbound voice applications independent of the hardware or geographical location of the telephony network. In addition, an improved opportunity for signaling of an appropriate moment for an application to leave a message is provided, thereby supporting automation. | 01-30-2014 |
20140223011 | Method and Apparatus For Supporting Scalable Multi-Modal Dialog Application Sessions - Embodiments disclosed herein enable scaling up and making advanced natural language (NLU) applications more robust. According to one embodiment, state(s) associated with a dialog session may be recorded to a fixed medium. The dialog session may be suspended after a given period of inactivity and later automatically awakened based on unique client, session, or device identifier, or any combination thereof. Memory and resources associated with the suspended session may be reclaimed, the memory and resources being otherwise held by the session during the period of inactivity, enabling higher density (e.g., a larger number of sessions supported). Embodiments disclosed herein obviate a need for sticky dialog sessions, enabling higher density, and may further failover protection and fault tolerance for the dialog sessions. | 08-07-2014 |
20150244642 | Method and Apparatus For Supporting Scalable Multi-Modal Dialog Application Sessions - Embodiments disclosed herein enable scaling up and making advanced natural language (NLU) applications more robust. According to one embodiment, state(s) associated with a dialog session may be recorded to a non-transitory medium. The dialog session may be suspended after a given period of inactivity and later automatically awakened based on unique client, session, or device identifier, or any combination thereof. Memory and resources associated with the suspended session may be reclaimed, the memory and resources being otherwise held by the session during the period of inactivity, enabling higher density (e.g., a larger number of sessions supported). Embodiments disclosed herein obviate a need for sticky dialog sessions, enabling higher density, and may further failover protection and fault tolerance for the dialog sessions. | 08-27-2015 |
Kenneth W. D. Smith, London GB
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20140201729 | Method and Apparatus for Supporting Multi-Modal Dialog Applications - An embodiment of the present invention includes a method for creating a dialog system that provides a framework for creating a multi-modal dialog application and includes a runtime application package (RAP) enabling runtime media grammars, prompts, classifiers, and so forth, to be separate from a multi-modal dialog application that utilizes the RAP. Embodiments disclosed herein enable newly trained runtime media supporting the multi-modal dialog application to be deployed with ease, and to do so while a dialog service is in operation. Embodiments disclosed herein enable the multi-modal dialog application to be created, deployed, and maintained in an easy and flexible manner, saving an end-user that may be providing the multi-modal dialog application to customers both time and cost. | 07-17-2014 |
Mark Edward Brennan Smith, London GB
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20150037360 | Lysosome-Cleavable Linker - The present invention relates to a linker for forming conjugates of a protein or peptide with a therapeutically active agent and which comprise a thiomaleamic acid moiety that is susceptible to cleavage under the pH conditions prevalent in the lysosome. | 02-05-2015 |
Nilufer Smith, London GB
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20080249462 | Disposable Dispensers for Personal Use - A syringe in accordance with the invention comprises a cylinder ( | 10-09-2008 |
Norman Smith, London GB
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20150265852 | PATIENT MONITOR - Images obtained by a camera system ( | 09-24-2015 |
Norman R. Smith, London GB
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20150045676 | Head Positioning Device - A head positioning device for use in radio therapy is described for positioning a patient's head. The head positioning device comprises a head plate for supporting a patient's head; a base plate for connection to a mechanical couch; and a head plate adjustment assembly connecting the head plate to the base plate wherein the head plate adjustment assembly is arranged to vary the relative pitch, yaw and roll of the head plate relative to the base plate. The head positioning device is arranged to be attached to a mechanical couch with the head plate and the head plate adjustment assembly cantilevered off the end of the couch and the head plate adjustment assembly suspended beneath the head plate and the base plate. | 02-12-2015 |
Norman Ronald Smith, London GB
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20090052760 | Image processing system for use with a patient positioning device - Three camera rigs ( | 02-26-2009 |
20090187112 | Patient monitor - A patient monitor is disclosed for detecting patient movement or abnormal breathing. Images of a patient are obtained by a stereoscopic camera. These images are then processed by a 3D position determination module which determines measurements indicative of positions of at least part of a patient. The obtained measurements are then passed to a model generation module which generates a breathing model of the variation in position of the at least part of a patient during a breathing cycle. Subsequently abnormal breathing or patient movement can be detected by processing further images obtained by the stereoscopic camera to determine more measurements indicative of positions of at least part of a patient. These measurements are then compared with a stored breathing model by a comparison module. If abnormal breathing or patient movement is detected the comparison module sends a signal to a treatment apparatus to interrupt treatment until normal breathing resumes or alternatively to a mechanical couch to reposition the patient to account for the detected movement. | 07-23-2009 |
20110178783 | Image processing system for use with a patient positioning device - Three camera rigs are connected by wiring to a computer. The computer is also connected to a treatment apparatus. A mechanical couch is provided as part of the treatment apparatus such that under the control of the computer the relative positions of the mechanical couch and the treatment apparatus may be varied. The camera rigs obtain video images of a patient lying on the mechanical couch the computer processes these images to generate a three-dimensional model of the surface of the patient which is utilized to position the patient relative to the treatment apparatus. | 07-21-2011 |
20150216450 | PATIENT MONITOR - A patient monitor is disclosed for detecting patient movement or abnormal breathing. Images of a patient are obtained by a stereoscopic camera. These images are then processed by a 3D position determination module which determines measurements indicative of positions of at least part of a patient. The obtained measurements are then passed to a model generation module which generates a breathing model of the variation in position of the at least part of a patient during a breathing cycle. Subsequently abnormal breathing or patient movement can be detected by processing further images obtained by the stereoscopic camera to determine more measurements indicative of positions of at least part of a patient. These measurements are then compared with a stored breathing model by a comparison module. If abnormal breathing or patient movement is detected the comparison module sends a signal to a treatment apparatus to interrupt treatment until normal breathing resumes or alternatively to a mechanical couch to reposition the patient to account for the detected movement. | 08-06-2015 |
Peter J. Smith, London GB
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20130104105 | TEST DATA SUPPLY CHAIN MANAGER FOR AN INTEGRATED TESTING PLATFORM - A method of supplying test data for test scripts is provided in an integrated testing platform, where the testing platform includes a prioritization and assignment manager configured forward test scripts to a selected testing individual. Each test script is mapped to an input data set if a corresponding input data set is available. Requests for test scripts made to the prioritization and assignment manager are monitored, and if the test script to be supplied in response to the request has a corresponding mapped input data set, the corresponding input data set is retrieved from a database, and the input data set is provided to the test script prior to execution of the test script. | 04-25-2013 |
20130104106 | AUTOMATION CONTROLLER FOR NEXT GENERATION TESTING SYSTEM - An automation controller for next generation testing system includes a database including a plurality of scripts and modules, a business layer component, and an automation component. The automation component includes an automation agent and an automation worker. The business layer component is operable to determine a next script from the plurality of scripts and modules and send the next script to the automation component in response to a get next script request sent by the automation component. The automation agent is operable to send the get next script request to the business layer, receive the next script from the business layer, and send the next script to the automation worker for execution. The automation worker is operable to execute the next script or section thereof, obtain a result, send status updates, send proof of life notifications and the result of execution to the automation agent. | 04-25-2013 |
Peter Michael Smith, London GB
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20120164099 | USE OF HUMAN PROSTATE CELL LINES IN CANCER TREATMENT - This invention is concerned with agents for the treatment of primary, metastatic and residual cancer in mammals (including humans) by inducing the immune system of the mammal or human afflicted with cancer to mount an attack against the tumour lesion. In particular, the invention pertains to the use of whole-cells, derivatives and portions thereof with or without vaccine adjuvants and/or other accessory factors. More particularly, this disclosure describes the use of particular combinations of whole-cells and derivatives and portions thereof that form the basis of treatment strategy. | 06-28-2012 |
Rebecca C. Smith, London CA
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20110213228 | ORAL DEVICE - An oral device for use with a person in which at least one non-toxic gas pulse is delivered to a predetermined location in the mouth via a device conduit. The oral device may be provided as a kit with at least one device for measuring the subject's responses and representing them as feedback to the subject/clinician. A method of creating a gas bolus pulse train, delivering it to a predetermined mouth area, and monitoring the subject's responses to it, is also shown. The oral device and method may be used as a diagnostic tool, or a therapeutic tool, in swallowing or speech rehabilitation of children and adults who have swallowing, speech, salivary, and/or oral sensorimotor impairments. | 09-01-2011 |
20130255674 | ORAL DEVICE - An oral device for use with a person in which at least one non-toxic gas pulse is delivered to a predetermined location in the mouth via a device conduit. The oral device may be provided as a kit with at least one device for measuring the subject's responses and representing them as feedback to the subject/clinician. A method of creating a gas bolus pulse train, delivering it to a predetermined mouth area, and monitoring the subject's responses to it, is also shown. The oral device and method may be used as a diagnostic tool, or a therapeutic tool, in swallowing or speech rehabilitation of children and adults who have swallowing, speech, salivary, and/or oral sensorimotor impairments. | 10-03-2013 |
Richard Anthony Godwin Smith, London GB
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20120232014 | ANTITHROMBOTIC COMPOUNDS - A soluble compound for preventing or reducing blood coagulation comprising an antithrombotic agent and a membrane binding element, wherein the antithrombotic agent has a weight of less than about 5,000 daltons. Also disclosed is a soluble compound for preventing or reducing blood coagulation comprising an anticoagulant joined to a membrane binding element via a joining element, wherein the joining element between the anticoagulant and the membrane binding element is less than about 10,000 daltons in weight. These compounds can be used in therapy and, in particular, in preventing or reducing blood coagulation. As a result, a method of treatment is provided comprising administering an effective amount of the compounds to a subject to prevent or reduce blood coagulation as well as a method of perfusing an organ, tissue or cell comprising contacting the compounds with the organ, tissue or cell to prevent or reduce blood coagulation. Also disclosed is an organ, tissue or cell which has been perfused with the compounds. | 09-13-2012 |
Stephen Alexander Calder Smith, London GB
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20140147898 | Separation Process - A process for treating a mixture of R,R- and S,S-lactide is provided. The process involves contacting the mixture with an aliphatic alcohol and an enzyme to produce a mixture comprising aliphatic ester of lactic acid corresponding to one lactide enantiomer and the aliphatic ester of lactyllactic acid corresponding to the other lactide enantiomer; separating the mixture from the enzyme, and recycling the enzyme to the process; and separating the aliphatic ester of lactic acid from the aliphatic ester of lactyl-lactic acid by fractional distillation. Also provided are processes for the production of S-lactic acid, S,S-lactide, poly-S-lactic acid, R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex polylactic acid. | 05-29-2014 |
20140342413 | Separation Process - A process for treating a mixture of R,R- and S,S-lactide is provided. The process involves contacting the lactide mixture with an aliphatic alcohol and/or an alkoxide to produce a mixture of R,R- and S,S-aliphatic ester of lactyllactic acid, subsequently contacting the mixture of R,R- and S,S-aliphatic ester of lactyllactic acid with an enzyme to produce a mixture comprising aliphatic ester of lactic acid corresponding to one lactide enantiomer and the aliphatic ester of lactyllactic acid corresponding to the other lactide enantiomer, and recovering the product. Also provided are processes for the production of S-lactic acid, S,S-lactide, poly-S-lactic acid, R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex polylactic acid. | 11-20-2014 |
20150240272 | LACTATE PRODUCTION PROCESS - A process for producing a compound of formula (I) is provided. The process comprises reacting a mixture comprising a compound of formula (IIA) and a compound of formula (IIB) with an alkyl alcohol in the presence of a | 08-27-2015 |
Stuart Colin Peter Smith, London GB
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20140143532 | DATA PROCESSING SYSTEM - An method and corresponding apparatus for detecting a change in an aspect of performance of a data processing system and for adjusting operation of a system so as to counter the detected change. The method generating a value representative of an aspect of performance of a data processing system relative to operation of the system in a first sub-period of each in a plurality of first time periods; in which each first sub-period is located with the same degree of offset within the respective first time period. The generated value may represent a norm or typical value for the aspect of behaviour in the sub-period. The method for detecting a change in the aspect of performance by comparing the value generated with a value indicative of the aspect of performance relative to operation of the system in a second sub-period of a second time period; in which the second sub-period is located with a degree of offset relative to the second time period that is the same as the degree of offset each first sub-period has relative to the respective first time period. The method also for initiating adjustment of operation of the system so as to counter the detected change in the aspect of performance of the system. | 05-22-2014 |