Patent application number | Description | Published |
20110033292 | ENERGY ABSORBING FAN BLADE SPACER - A gas turbine engine fan section is disclosed that includes a hub. Circumferentially spaced fan blades are supported on the hub. A spacer is arranged between adjacent fan blades and is operatively supported by the hub. The spacer is configured to be collapsible in response to a fan blade load exerted on the spacer in excess of a threshold load. The spacer is generally rigid at fan blade loads below the threshold load. | 02-10-2011 |
20110033308 | TITANIUM SHEATH AND AIRFOIL ASSEMBLY - An airfoil assembly includes an airfoil body extending between a leading edge, a trailing edge, a suction side, and a pressure side. A first sheath having an outer side and an inner side forms a cavity for receiving at least a portion of the airfoil body and is bonded on the inner side to the leading edge of the airfoil body. The first sheath is formed of a titanium-based metallic material. A second sheath is bonded to the outer side of the first sheath. | 02-10-2011 |
20110038732 | GAS TURBINE ENGINE COMPOSITE BLADE - The disclosed composite airfoil includes a three-dimensional composite core extending longitudinally and having a chord-wise direction. The core has a core in-plane thickness extending between opposing sides in a through-plane direction generally perpendicular to the chord-wise and longitudinal directions. A composite skin covers the opposing sides and has an exterior surface providing an airfoil contour. The skin includes a total skin in-plane thickness corresponding to a sum of thicknesses through the skin in the through-plane direction from each of the opposing sides to their adjoining exterior surface. A sum of the core in-plane and total skin in-plane thicknesses at a central portion of the composite airfoil is a total in-plane thickness. The total skin in-plane thickness at the central portion is less than 50% of the total in-plane thickness. | 02-17-2011 |
20110116906 | AIRFOIL COMPONENT WEAR INDICATOR - An example airfoil assembly includes an airfoil body extending between a leading edge, a trailing edge, a suction side, and a pressure side. The assembly further includes a first protective sheath, an indicator sheath, and a second protective sheath. The first protective sheath has an outer side and an inner side that forms a cavity for receiving at least a portion of the airfoil body. The inner side being bonded to the leading edge of the airfoil body. A portion of the indicator sheath is positioned forward the first sheath relative to the leading edge of the airfoil. A portion of the second protective sheath is positioned forward the indicator sheath relative to the leading edge of the airfoil. | 05-19-2011 |
20110129348 | CORE DRIVEN PLY SHAPE COMPOSITE FAN BLADE AND METHOD OF MAKING - A method of forming a composite airfoil having a suction side and pressure side includes the steps of designing a mold, designing a woven core, designing a plurality of plies and assembling the designed mold, core and plies to create the composite airfoil. The hollow mold has an inner surface which defines the surface profile of the composite airfoil. The plurality of plies is designed to fit between the inner surface of the mold and an outer surface of the woven core. The plurality of plies is designed after the step of designing the woven core. | 06-02-2011 |
20110194941 | CO-CURED SHEATH FOR COMPOSITE BLADE - A method of forming a composite blade having a sheath on a portion of the blade by placing the dry composite blade and sheath in a mold, adding a resin, and curing the resin to integrally bond the blade to the metal sheath. The portion of the blade having the sheath bonded thereto may be at least one of the leading edge, the tip and the trailing edge of the blade. | 08-11-2011 |
20110223027 | COMPOSITE FAN BLADE DOVETAIL ROOT - A composite fan blade having an airfoil with a leading edge and a trailing edge and a dovetail root includes a first pressure face and second pressure face, a lower horizontal face connecting the pressure faces at the bottom of the dovetail and a first and a second dovetail runout fillet connecting the pressure faces to the airfoil. The pressure faces are each angled outward at about 65 degrees to about 75 degrees from horizontal. | 09-15-2011 |
Patent application number | Description | Published |
20080306751 | SYSTEMS AND METHODS FOR MANAGING BUSINESS PROCESSES IN AN ENTERPRISE - A method for managing a business process in an enterprise includes executing a business process model, wherein executing the business process model comprises generating a plurality of business level messages associated with business level tasks, generating one or more system level messages associated with system level tasks to be performed by one or more enterprise subsystems, wherein the one or more system level messages are in a common format that is accessible by the one or more enterprise subsystems, and broadcasting the one or more system level messages over a communication channel communicably coupling the plurality of enterprise subsystems. A system includes a communication channel carrying system level messages in a generic format, a plurality of business subsystems communicably coupled to the communication channel, adapters operable to translate messages from the generic format into associated business subsystem specific formats and vice versa. | 12-11-2008 |
20130066685 | SYSTEMS AND METHODS FOR MANAGING BUSINESS PROCESSES IN AN ENTERPRISE - A method for managing a business process in an enterprise includes executing a business process model, wherein executing the business process model comprises generating a plurality of business level messages associated with business level tasks, generating one or more system level messages associated with system level tasks to be performed by one or more enterprise subsystems, wherein the one or more system level messages are in a common format that is accessible by the one or more enterprise subsystems, and broadcasting the one or more system level messages over a communication channel communicably coupling the plurality of enterprise subsystems. A system includes a communication channel carrying system level messages in a generic format, a plurality of business subsystems communicably coupled to the communication channel, adapters operable to translate messages from the generic format into associated business subsystem specific formats and vice versa. | 03-14-2013 |
Patent application number | Description | Published |
20090098576 | Feline Pancreatic Lipase - Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples. | 04-16-2009 |
20100267131 | Feline Pancreatic Lipase - Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples. | 10-21-2010 |
Patent application number | Description | Published |
20080273171 | METHODS AND DEVICES FOR MEASURING TEAR FILM AND DIAGNOSING TEAR DISORDERS - Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release. | 11-06-2008 |
20090201465 | METHODS AND DEVICES FOR MEASURING TEAR FILM AND DIAGNOSING TEAR DISORDERS - Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release. | 08-13-2009 |
20110199576 | METHODS AND DEVICES FOR MEASURING TEAR FILM AND DIAGNOSING TEAR DISORDERS - Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release. | 08-18-2011 |
20120002169 | METHODS AND DEVICES FOR MEASURING TEAR FILM AND DIAGNOSING TEAR DISORDERS - Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release. | 01-05-2012 |
20120105803 | METHODS AND DEVICES FOR MEASURING TEAR FILM AND DIAGNOSING TEAR DISORDERS - Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release. | 05-03-2012 |
20150351626 | METHOD FOR RAPID CALCULATION OF TEAR FILM LIPID AND AQUEOUS LAYER THICKNESS AND OCULAR SURFACE REFRACTIVE INDEX FROM INTERFEROMETRY SPECTRA - A method for determining optical properties of a corneal region. The method includes the steps of obtaining a combined tear film aqueous layer plus lipid layer thickness; obtaining a tear film lipid layer thickness; subtracting the tear film lipid layer thickness from the combined tear film aqueous layer plus lipid layer thickness to obtain a tear film aqueous layer thickness; and determining a corneal layer refractive index based on the tear film lipid layer thickness and the tear film aqueous layer thickness. | 12-10-2015 |
20150351627 | FAST ABSOLUTE-REFLECTANCE METHOD FOR THE DETERMINATION OF TEAR FILM LIPID LAYER THICKNESS - A method of determining tear film lipid layer thickness. The method includes the steps of measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; and comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness. | 12-10-2015 |
Patent application number | Description | Published |
20090318512 | Methods of maintaining ocular tissue cell membrane integrity using cetylpyridinium chloride - A multi-purpose contact lens care solution having high antimicrobial activity comprising, in an aqueous liquid medium, cetylpyridinium chloride and a non-ionic surfactant. In one embodiment of the invention, the non-ionic surfactant is a poly(oxypropylene)-poly(oxyethylene) block copolymer. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear. | 12-24-2009 |
20120093894 | STABLE CYCLOSPORINE CONTAINING OPHTHALMIC EMULSION FOR TREATING DRY EYES - Disclosed herein are stable oil-in-water emulsion ophthalmic topical liquid compositions having an average particle size less than 1 μm including at least one plant-derived oil other than castor oil wherein the oil comprises only aliphatic side chains free of polar pendent groups. The oil-in-water emulsion ophthalmic topical liquid compositions also include a hydrophilic surfactant having an HLB value between approximately 10 and 14, a vegetable oil-derived hydrophobic non-co-block surfactant having unsaturated side chains that contain less than four oxygen atoms having an HLB value between approximately 4 and 6 and is a liquid at room temperature. The oil-in-water emulsion ophthalmic topical liquid compositions disclosed herein can further include an amount of cyclosporine A or polyphenol in an amount effective to relieve dry eye symptoms. | 04-19-2012 |
20120288470 | OPHTHALMIC SYSTEM WITH SYNERGISTIC PROPERTIES - Disclosed herein are ophthalmic cleaning systems and methods for their use, which comprise an ophthalmic solution and lens case, wherein the solution includes dual disinfectants and the lens case includes silver. When the lens case is combined with the solution according to the system of the present invention, it surprisingly exhibits synergistic activity which results in a faster antimicrobial activity. | 11-15-2012 |
20130208246 | METHODS AND DEVICES FOR MEASURING TEAR FILM AND DIAGNOSING TEAR DISORDERS - Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release. | 08-15-2013 |
20140161904 | OPHTHALMIC SYSTEM WITH SYNERGISTIC PROPERTIES - Disclosed herein are ophthalmic cleaning systems and methods for their use, which comprise an ophthalmic solution and lens case, wherein the solution includes dual disinfectants and the lens case includes silver. When the lens case is combined with the solution according to the system of the present invention, it surprisingly exhibits synergistic activity which results in a faster antimicrobial activity. | 06-12-2014 |
20140275274 | SYNERGISTIC OPHTHALMIC COMPOSITIONS FOR DISINFECTING CONTACT LENSES - Compositions and methods for disinfecting contact lenses using the compositions are disclosed. The compositions include a combination of alexidine and chlorhexidine, which surprisingly causes the composition to exhibit synergistic antimicrobial activity against | 09-18-2014 |
20150351628 | FAST ABSOLUTE-REFLECTANCE METHOD FOR THE DETERMINATION OF TEAR FILM LIPID LAYER THICKNESS - A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light. | 12-10-2015 |