Patent application number | Description | Published |
20080305476 | Immunoassay Methods - The invention relates to a method of detecting a disease state or disease susceptibility in a mammalian subject which comprises detecting an antibody in a test sample comprising a bodily fluid from said mammalian subject wherein said antibody is a biological marker of a disease state or disease susceptibility, the method comprising: (a) contacting said test sample with a plurality of different amounts of an antigen specific for said antibody, (b) detecting the amount of specific binding between said antibody and said antigen, (c) plotting or calculating a curve of the amount of said specific binding versus the amount of antigen for each amount of antigen used in step (a) and (d) determining the presence or absence of said disease state or disease susceptibility based upon the amount of specific binding between said antibody and said antigen at each different antigen concentration used. | 12-11-2008 |
20110086061 | Cancer Detection Methods and Reagents - The present invention comprises methods and compositions for detecting cancer in an individual comprising autoantibodies to cancer-associated antigens. Specifically, the present invention comprises methods and compositions for detecting autoantibodies to cancer-associated antigen in a bodily fluid as well as use of said autoantibodies as a means to detect the presence of cancer-associated antigens. | 04-14-2011 |
20140080736 | TUMOUR MARKER PROTEINS AND USES THEREOF - Tumour marker proteins and their preparation from fluids from one or more cancer patients, wherein said fluids are those which collect in a body cavity or space which is naturally occurring or which is the result of cancer or medical intervention for cancer. The present application also relates to preparation of tumour marker proteins from excretions taken from patients with cancer. The tumour marker proteins are useful as immunoassay reagents in the detection of cancer-associated anti-tumour marker autoantibodies. | 03-20-2014 |
20140221245 | IMMUNOASSAY METHODS - The invention relates to a method of detecting a disease state or disease susceptibility in a mammalian subject which comprises detecting an antibody in a test sample comprising a bodily fluid from said mammalian subject wherein said antibody is a biological marker of a disease state or disease susceptibility, the method comprising: (a) contacting said test sample with a plurality of different amounts of an antigen specific for said antibody, (b) detecting the amount of specific binding between said antibody and said antigen, (c) plotting or calculating a curve of the amount of said specific binding versus the amount of antigen for each amount of antigen used in step (a) and (d) determining the presence or absence of said disease state or disease susceptibility based upon the amount of specific binding between said antibody and said antigen at each different antigen concentration used. | 08-07-2014 |
20140234863 | IMMUNOASSAY METHODS - The invention relates to a method of detecting a disease state or disease susceptibility in a mammalian subject which comprises detecting an antibody in a test sample comprising a bodily fluid from said mammalian subject wherein said antibody is a biological marker of a disease state or disease susceptibility, the method comprising: (a) contacting said test sample with a plurality of different amounts of an antigen specific for said antibody, (b) detecting the amount of specific binding between said antibody and said antigen, (c) plotting or calculating a curve of the amount of said specific binding versus the amount of antigen for each amount of antigen used in step (a) and (d) determining the presence or absence of said disease state or disease susceptibility based upon the amount of specific binding between said antibody and said antigen at each different antigen concentration used. | 08-21-2014 |
Patent application number | Description | Published |
20080213921 | Immunoassay Methods - The invention generally relates to the field of diagnostic or prognostic assays and in particular relates to assays for the detection of antibodies in a sample comprising patient bodily fluid, wherein such antibodies are used as biological markers of a disease state or disease susceptibility. The assay is based on cross-titration of both the patient bodily fluid to be tested for the antibody and an antigen used to detect the antibody by specific binding. | 09-04-2008 |
20120115749 | Tumour Markers - A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigen. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient. | 05-10-2012 |
20130090251 | Tumour Markers - A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigen. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient. | 04-11-2013 |
20140038212 | IMMUNOASSAY METHODS - The application generally relates to the field of diagnostic or prognostic assays and in particular relates to assays for the detection of antibodies in a sample comprising patient bodily fluid, wherein such antibodies are used as biological markers of a disease state or disease susceptibility. The assay is based on cross-titration of both the patient bodily fluid to be tested for the antibody and an antigen used to detect the antibody by specific binding. | 02-06-2014 |
Patent application number | Description | Published |
20090091192 | Socket Assembly With Standby Sockets - A power distribution apparatus for use with a master device and suite of peripheral devices, comprising a master electrical outlet and at least one standby electrical outlet, both connectable to a common electrical power supply. The apparatus further comprising sensing means for detecting changes in the operating state of master device and a controller operable to interrupt power to the at least one standby electrical outlet when the sensing means detects a prescribed change in operating state of the master device. In which, following an interruption of power, the controller automatically restores power to the at least one standby electrical outlet after a predetermined interval of time, thereby providing at least a standby power to any peripheral device connected to the standby outlet when the master device is off or on standby. In this way, peripheral devices may then enter standby states of operation, if equipped to do so. | 04-09-2009 |
20090125743 | Socket Assembly With Data Traffic Sensing - A power distribution apparatus for use with a suite of master and peripheral devices, comprising a master electrical outlet and at least one slave electrical outlet, both connectable to a common electrical power supply. The apparatus further comprising a monitoring means for monitoring data traffic, e.g. USB bus signals, associated with a master device such as a personal computer, and a controller for interrupting power to the at least one slave electrical outlet in response to the monitoring means detecting a prescribed change in the data traffic of the master device. | 05-14-2009 |
20090307505 | Sensing Socket Assembly - A power distribution apparatus to control the supply of electrical power to a suite of master and peripheral devices, the apparatus comprising a master electrical outlet and at least one slave electrical outlet, both connectable to a common power supply. The apparatus including a sampling means adapted to sample power drawn from the master electrical outlet, and a controller adapted to calculate an updating average of a plurality of sampled power levels and operable to isolate the slave electrical outlet from the power supply in response to a prescribed change in the calculated average power drawn from the master electrical outlet relative to an automatically calculated switching threshold. | 12-10-2009 |