Patent application number | Description | Published |
20080293135 | Co-Culture Bioreactor System - Disclosed are multi-chambered cell co-culture systems. The systems can be utilized to encourage the growth and development of isolated cells in a dynamic three-dimensional in vitro environment. The cell chambers ( | 11-27-2008 |
20090142505 | Needle-to-Needle Electrospinning - The disclosure relates to a method and apparatus for coating a medical device. The method includes providing an electrospinning apparatus and simultaneously electrospinning at least one solution onto a first surface and an opposing second surface. The apparatus comprises a first spinneret and a second spinneret. An energy source is electrically coupled to the first spinneret and the second spinneret. The first spinneret and second spinneret comprise a reservoir and an orifice fluidly coupled to the reservoir. The first spinneret orifice is located substantially opposite the second spinneret orifice. | 06-04-2009 |
20090215176 | Differential Pressure Pump System - The present disclosure is directed to a fluid pumping mechanism that uses differential pressure to drive flow through one or more culture chambers. Fluid contained within a first chamber can be caused to flow through one or more culture chambers and thence to a second chamber upon establishment of a pressure differential between the two chambers. The differential pressure system can induce either steady state or pulsatile flow through a culture chamber. In one embodiment, a culture chamber can be held at a high or low pressure hydrostatic state through utilization of the disclosed systems. | 08-27-2009 |
20100057195 | BARBED ANCHORS FOR WIRE STENT - An endoluminal prosthesis that includes a support structure comprising a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body and where the anchor body fits at least partially about, and conforms to the first strut, second strut, and the apex. | 03-04-2010 |
20100323052 | NEEDLE-TO-NEEDLE ELECTROSPINNING - The disclosure relates to a method and apparatus for coating a medical device. The method includes providing an electrospinning apparatus and simultaneously electrospinning at least one solution onto a first surface and an opposing second surface. The apparatus comprises a first spinneret and a second spinneret. An energy source is electrically coupled to the first spinneret and the second spinneret. The first spinneret and second spinneret comprise a reservoir and an orifice fluidly coupled to the reservoir. The first spinneret orifice is located substantially opposite the second spinneret orifice. | 12-23-2010 |
Patent application number | Description | Published |
20110137403 | INTRODUCER FOR ENDOVASCULAR IMPLANTS - An introducer assembly for introducing a stent-graft or other device into a vessel of a patient is provided with a dilator tip which is naturally curved, preferably to be substantially a U-shape. The dilator tip is flexible so as to be able to become substantially straight with a guide wire therein and yet to be able to curve back towards its natural curvature during deployment of an implant. The curvature of the dilator tip can ensure that the dilator tip does not cause damage to the vessel wall during deployment of an implant carried thereon, as can occur with straight dilator tips. | 06-09-2011 |
20110166516 | BALLOON CATHETERS HAVING A PLURALITY OF NEEDLES FOR THE INJECTION OF ONE OR MORE THERAPEUTIC AGENTS - There are disclosed apparatus and methods for treating tissue by delivering at least one therapeutic agent into the tissue. In one embodiment, the apparatus comprises a catheter ( | 07-07-2011 |
20110270374 | SYSTEM AND METHOD FOR DEPLOYING AND POSITIONING AN ENDOVASCULAR DEVICE - A dilator tip ( | 11-03-2011 |
20120078348 | APPARATUS AND METHODS FOR DELIVERING AT LEAST ONE THERAPEUTIC AGENT - The present invention provides apparatus and methods for treating tissue by delivering at least one therapeutic agent to the tissue. In one embodiment, the apparatus comprises first and second membranes ( | 03-29-2012 |
20120136425 | SLOTTED PUSHER ROD FOR FLEXIBLE DELIVERY SYSTEM - A delivery system for an intraluminal medical device comprises an elongate tubular sheath | 05-31-2012 |
20120141656 | NEEDLE-TO-NEEDLE ELECTROSPINNING - An electrospinning apparatus may include a first spinneret and a second spinneret, each including a reservoir and an orifice. The first and second spinnerets may have first and second electrical charges, respectively. The first spinneret orifice may be located substantially opposite the second spinneret orifice. The first and second spinnerets may be used to prepare a medical device defining a lumen with a proximal end, a distal end, a luminal surface and an abluminal surface. The first spinneret orifice distal end may be configured to be located outside of the medical device lumen and between about 0.1 inches and about 6.0 inches from the medical device abluminal surface. The second spinneret orifice distal end may be configured to be located in the medical device lumen and between about 0.1 inches and about 6.0 inches from the medical device luminal surface. | 06-07-2012 |
20120183987 | CO-CULTURE BIOREACTOR SYSTEM - Disclosed herein are bioreactor systems and methods of utilizing said systems. | 07-19-2012 |
20130190858 | BARBED ANCHORS FOR WIRE STENT - An endoluminal prosthesis that includes a support structure comprising a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body and where the anchor body comprises a multi-filar tube fits at least partially about, and conforms to the first strut, second strut, and the apex. | 07-25-2013 |
20130237909 | BALLOON CATHETERS HAVING A PLURALITY OF NEEDLES FOR THE INJECTION OF ONE OR MORE THERAPEUTIC AGENTS - There are disclosed apparatus and methods for treating tissue by delivering at least one therapeutic agent into the tissue. In one embodiment, the apparatus comprises a catheter and a balloon member disposed on a distal region of the catheter. A plurality of pockets are disposed on the balloon member, and a plurality of needles are associated with each of the plurality of pockets. The plurality of needles are configured to engage tissue when the balloon is in the inflated state, and further are configured to disperse a therapeutic agent from an associated pocket into the tissue when the balloon is in the inflated state. A first needle of the plurality of needles may comprise a length that is different than a second needle, permitting the delivery of first and second therapeutic agents to different depths within the tissue. | 09-12-2013 |
20130309771 | BIOREACTOR SYSTEM - Disclosed herein are bioreactor systems and methods of utilizing said systems. | 11-21-2013 |
20140243951 | TAPERED STENT AND FLEXIBLE PROSTHESIS - The disclosure relates to a tapered stent and flexible prosthesis. The stent has a first longitudinal region and a second longitudinal region. The second region is substantially parallel to and spaced axially apart from the first region. A plurality of struts is disposed intermediate the first region and the second region and circumferentially connects the first region and the second region. The first region has a longitudinal length that is greater than the second region longitudinal length. The struts have varying longitudinal lengths that gradually decrease from the first region to the second region. The flexible prosthesis comprises at least two alternating tapered stents. | 08-28-2014 |
20150079584 | BIOREACTOR SYSTEM - A three dimensional cell culture and bioreactor system is provided. The system comprises one or more cell culture chamber. Each cell culture chamber comprises an inlet port and an outlet port in fluid communication with the cell culture chamber. The cell culture chambers may be segregated or in fluid communication with one another. The systems may be used to conduct drug efficacy test, isolate certain cell types from a complex tissue sample of multiple cell types, allow for the ex vivo culturing of patient tissue samples to help guide the course of treatment, and conduct co-culture experiments. | 03-19-2015 |