Patent application number | Description | Published |
20090010982 | BIOCOMPATIBLE ADHERENT SHEET FOR TISSUE SEALING - A biocompatible adherent sheet for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The biocompatible adherent sheet includes a carrier sheet including a biocompatible polymer and a modified chitosan evenly disposed on one or both sides of the carrier sheet. Methods of preparing a biocompatible adherent sheet and methods of using a biocompatible adherent sheet are also provided. The biocompatible adherent sheet may also include a bioactive agent. | 01-08-2009 |
20100029789 | Load Bearing Hydrogel Implants - The present invention features dual network hydrogels that possess the structural, mechanical, and biological properties required of load bearing three-dimensional support structures. | 02-04-2010 |
20100178346 | DISC AUGMENTATION WITH HYALURONIC ACID - The present invention relates to materials comprising hyaluronic acid for replacement or augmentation of the nucleus pulposus The materials have a Poisson's ratio of 0.40 to 0.80 based on that of the human nucleus pulposus. | 07-15-2010 |
20100233267 | COMPOSITE HYDROGEL - The present invention features a composite hydrogel for use as soft tissue substitutes and transitional three-dimensional support structures. | 09-16-2010 |
20110002999 | Biopolymer System for Tissue Sealing - A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises alkylated chitosan or a gelatin, and a polybasic carboxylic acid or an oxidized polysaccharide, in an aqueous medium. The premix can also include a dehydrating reagent, a carboxyl activating reagent, or both. A specific use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug. | 01-06-2011 |
20140107065 | Biopolymer System for Tissue Sealing - A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises alkylated chitosan or a gelatin, and a polybasic carboxylic acid or an oxidized polysaccharide, in an aqueous medium. The premix can also include a dehydrating reagent, a carboxyl activating reagent, or both. A specific use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug. | 04-17-2014 |