Patent application number | Description | Published |
20080292556 | Target Vector with Activable Imaging Function - The invention concerns the field of molecular probe architecture for in vivo imaging. More particularly, the invention concerns molecular constructs providing an imaging function activable in intracellular environment, said constructs being further bound to a vector which enables certain cells to be targeted, and said cells to be internalized. The inventive fluorescence probes enable in particular images of certain targeted tissues to be formed, while maintaining a low background noise level and, preferably, while obtaining at the targeted tissue, an imaging signal increasing in time. | 11-27-2008 |
20080299044 | Saccharide Fluorescent Substrates, Preparation Method and Uses Thereof - The invention concerns saccharide type fluorescent enzymatic substrates comprising on the same saccharide unit a fluorophor F1 and an inhibitor of the fluorescence of F1, and their use for preparing a diagnostic reagent for in vivo functional imaging, as well as a diagnostic reagent containing at least such an enzymatic substrate. | 12-04-2008 |
20090081634 | FLUORESCENT AND SACCHARIDIC SUBSTRATES, THEIR PROCESS OF PREPARATION AND THEIR USE - The present invention relates to fluorescent enzymatic substrates of saccharidic nature having a self-cleavable spacer arm functionalized by a fluorophore F and by at least one inhibitor of the fluorescence of F, to the use thereof for preparation of a diagnostic reagent for functional imaging in vivo, and to the diagnostic reagent for functional imaging containing at least one such enzymatic substrate. | 03-26-2009 |
20100144899 | METHOD FOR PREPARING NANO-EMULSIONS - The present invention relates to a method for preparing nano-emulsions comprising at least one aqueous continuous phase and at least one oily dispersed phase, comprising the steps of:
| 06-10-2010 |
20100200813 | SEMICONDUCTOR NANOCRYSTALS - The present invention aims to provide a method of use for surface-modifying a semiconductor nanocrystal comprising at least the steps consisting in having a semiconductor nanocrystal, the organic coating layer of which is provided, at the outer surface of the nanocrystal, with at least one reactive group G1 that reacts according to a cycloaddition reaction of click chemistry type; and bringing said nanocrystal together with an adjoining material provided at the surface with at least one G2 group complementary to the G1 group with respect to said click chemistry reaction, under conditions favourable to the interaction of said G1 and G2 groups, characterized in that said G1 and G2 groups are respectively an azide and a strained cycloalkynyl radical, or vice versa. | 08-12-2010 |
20100284932 | FLUORESCENT EMULSIONS FOR OPTICAL IMAGING - The invention relates to a fluorescent emulsion, to a diagnostic reagent containing the same, and to the use thereof in the preparation of a diagnostic reagent for in vivo fluorescence imaging. | 11-11-2010 |
20110118484 | PROCESS FOR THE FUNCTIONALIZATION OF BIOLOGICAL MOLECULES - The present invention is targeted at a novel coupling method of 1,3-dipolar cycloaddition type which is of particular use for the functionalization of biological molecules, such as, for example, proteins, enzymes or nucleic acids, insofar as it can be carried out in an aqueous medium and at ambient temperature. | 05-19-2011 |
20110195029 | FLUORESCENT EMULSION - The invention relates to a fluorescent emulsion, to its uses and to labelling reagents comprising it. | 08-11-2011 |
20110200532 | Fluorescent emulsion of indocyanine green - The present invention relates to a formulation of indocyanine green in the form of a nanoemulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily phase comprises indocyanine green, at least one amphiphilic lipid and at least one solubilising lipid. | 08-18-2011 |
20110201695 | Encapsulation of lipophilic or amphiphilic therapeutic agents in nano-emulsion - The present invention relates to a therapeutic agent formulation in the form of a nano-emulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily phase comprises further to the therapeutic agent, at least one amphiphilic lipid and at least one solubilising lipid, and in which the aqueous phase comprises at least one polyalkoxylated cosurfactant. | 08-18-2011 |
20110274622 | Nanocrystal Nano-Emulsion - The invention relates to a nanocrystal formulation in the form of a nano-emulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily phase comprises at least one amphiphilic lipid and at least one solubilising lipid, and in which the aqueous phase comprises a cosurfactant. | 11-10-2011 |
20120037871 | NOVEL BIFUNCTIONAL MOLECULES COMPRISING A CYCLOALKYNE OR HETEROCYCLOALKYNE GROUP AND A REDOX GROUP - The invention relates to compounds comprising a cycloalkyne or heterocycloalkyne group and a redox group. Said compounds are of general formula (I) wherein Z is a cycloalkyne or heterocycloalkyne with at least 8 links, optionally substituted by a halogen atom or a linear or branched C1 to C5 alkyl, A is an organic structure having oxidation-reduction properties, and B is an organic link between the cycloalkyne or heterocycloalkyne cycle and the organic structure A. The invention is especially applicable to the field of molecular electronics. | 02-16-2012 |
20120061627 | FLUORESCENT NANOPARTICLES, METHOD FOR PREPARING SAME, AND APPLICATION THEREOF IN BIOLOGICAL MARKING - A method for preparing nanocrystals is disclosed. According to one aspect, the noncrystals include a semiconductor ternary compound consisting of the elements A, B and C. According to another aspect, the nanocrystals include a semiconductor of formula ABC | 03-15-2012 |
20120095203 | NOVEL SILANE COMPOUNDS HAVING A CYCLIC CARBON CHAIN INCLUDING AN ALKYNE FUNCTION FOR FUNCTIONALISING SOLID SUBSTRATES AND IMMOBILISING BIOLOGICAL MOLECULES ON SAID SUBSTRATES - The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH | 04-19-2012 |
20120095247 | METHOD FOR SURFACE FUNCTIONALIZATION BY DISUBSTITUTED ALKYNES - The invention relates to the use of disubstituted alkynes for the functionalisation of the surface of a substrate consisting of a semi-conductor material, with molecules of interest. According to the invention, a compound of formula A-(E1) | 04-19-2012 |
20130261096 | Formulation For Hormonotherapy - The present invention relates to a formulation as a nanoemulsion, comprising a continuous aqueous phase and at least one dispersed phase, and comprising:
| 10-03-2013 |
20150030543 | Formulas for Diagnosing and Treating Hormone-Dependent Cancers and Cancers of the Organs Responsible for Steroid Hormone Synthesis - The present invention relates to a formulation of a therapeutic or diagnostic agent in the form of a nano-emulsion, to its preparation method and to the use of this formulation for treating or diagnosing hormone-dependent cancers or cancers of organs synthesizing steroidal hormones. | 01-29-2015 |
20150057374 | MATERIAL, METHOD FOR PREPARING SAME, AND USES THEREOF - A material including a continuous aqueous phase and a dispersed phase in the form of droplets containing an amphiphilic lipid and a surfactant having the following formula (I): | 02-26-2015 |