Faulstich
Andreas Faulstich, Schwalbach DE
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20100026963 | OPTICAL PROJECTION GRID, SCANNING CAMERA COMPRISING AN OPTICAL PROJECTION GRID AND METHOD FOR GENERATING AN OPTICAL PROJECTION GRID - The present invention relates to an optical projection grid ( | 02-04-2010 |
Heinz Faulstich, Heidelberg DE
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20120100161 | Amatoxin-Armed Therapeutic Cell Surface Binding Components Designed for Tumour Therapy - The invention relates to tumour therapy. In one aspect, the present invention relates to conjugates of a toxin and a target-binding moiety, e.g. an antibody, which are useful in the treatment of cancer. In particular, the toxin is an amatoxin, and the target-binding moiety is preferably directed against tumour-associated antigens. In particular, the amatoxin is conjugated to the antibody by linker moieties. In particular the linker moieties are covalently bound to functional groups located in positions of the amatoxin proved as preferred positions for the attachment of linkers with respect to optimum antitumor activity. In a further aspect the invention relates to pharmaceutical compositions comprising such target-binding moiety toxin conjugates and to the use of such target-binding moiety toxin conjugates for the preparation of such pharmaceutical compositions. The target-binding moiety toxin conjugates and pharmaceutical compositions of the invention are useful for the treatment of cancer. | 04-26-2012 |
20120213805 | Amatoxin-Armed Tartget-Binding Moieties for the Treatment of Cancer - The invention relates to tumour therapy. In one aspect, the present invention relates to conjugates of target-binding moieties and toxins that are useful in the treatment of cancer. In particular, the toxin is an amatoxin, and the target-binding moieties (e.g. antibodies) are directed against tumour-associated antigens, such as epithelial cell adhesion molecule (EpCAM). In a further aspect the invention relates to pharmaceutical compositions comprising such target-binding moiety toxin conjugates and to the use of such target-binding moiety toxin conjugates for the preparation of such pharmaceutical compositions. The target-binding moiety toxin conjugates and pharmaceutical compositions of the invention are useful for the treatment of cancer, in particular adenocarcinoma, such as pancreatic cancer, cholangiocarcinoma, breast cancer, and colorectal cancer. | 08-23-2012 |
Ingo Faulstich, Ludwigsburg DE
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20080292420 | Diagonal generating method to generate tooth flanks with specified twist at specified flank line crowning - By coordinating the amount and course of the crowning of the tool and the diagonal ratio, a twist is created with a simple tool, and superimposed on the natural twist, thus resulting in the twist required for the work piece. Furthermore, an additional portion of the crowning is superimposed on the portion of the crowning of the work piece which is the result of the crowning of the tool during the machining in the diagonal method, thus resulting in the required crowning of the work piece, with said additional portion of the crowning being generated by changing the spacing between tool and work piece during the machining. | 11-27-2008 |
20090053977 | Tool and method for discontinuous profile grinding - A gear grinding tool can be trued and re-profiled. The geometry of the individual profiles in the direction of the tool axis is designed so that at least more than two, preferably all, flanks of the tool are used for rough machining of the work piece flanks, and that during finishing the re-profiled flanks provided only for roughing are set back far enough so that during finishing they do not come into contact with the work piece flanks. | 02-26-2009 |
20110250029 | METHOD FOR MACHINING THE FLANKS OF SUBSTANTIALLY CYLINDRICAL GEARING HAVING MODIFIED CROWNING, IN A DIAGONAL ROLLING METHOD - The invention concerns a method of machining the tooth flanks of substantially cylindrical, but crowning-modified gears through a diagonal generating process employing a worm-shaped tool which is modified with a crowning in the direction of its rotary axis, wherein the crowning can be positive or negative (concave crowning), wherein by matching the crowning of the tool to the diagonal ratio, a flank twist is generated by means of the tool and superimposed on the natural flank twist, such that the result of said superposition equals the flank twist required for the work piece. | 10-13-2011 |
Konard Faulstich, Salem-Neufrach DE
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20100184159 | Compositions, Methods, and Kits for Selective Amplification of Nucleic Acids - The current teachings are directed to compositions, methods, and kits for selectively amplifying and for detecting target sequences. In some embodiments, a circularizable probe and/or a probe pair are disclosed for selectively amplifying target sequences. Methods for selectively amplifying target sequences are also disclosed, as are methods for detecting selectively amplified target sequences. Certain embodiments of the disclosed methods comprise a circularizable probe, a probe pair, comprising a first probe and a second probe, or both. In certain embodiments, a multiplicity of different circularizable probes, a multiplicity of different probe sets, or a multiplicity of different circularizable probes and a multiplicity of different probe sets are provided to selectively amplify or to detect a multiplicity of different target sequences, typically in a multiplex reaction. According to certain disclosed methods, surrogates of the target sequences are selectively amplified, including without limitation ligated probes, first amplification products, second amplification products, or combinations thereof. In some embodiments, selectively amplified target sequences or their surrogates are detected, directly or indirectly, indicating the presence of the corresponding target sequence. Kits to facilitate the performance of the disclosed methods are also provided. | 07-22-2010 |
Markus Faulstich, Raunheim DE
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20150033524 | PRESSING TOOL AND METHOD FOR MANUFACTURING A PRESSING TOOL - A method for manufacturing a pressing tool includes shaping a blank, which is able to be hardened, at least in part, to a final size of a pressing jaw. Then, a laser beam is applied to at least one selected region of a surface of the pressing jaw so as to form at least one hardened surface layer. | 02-05-2015 |
Michael Faulstich, Cedar Park, TX US
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20090139020 | NECK JET PILLOW FOR WHIRLPOOL TUB OR SPA - A neck jet pillow for a spa or whirlpool tub removably mountable. The pillow has a soft membrane area occupying a central portion thereof, a first mounting member fixedly mountable onto a fluid jet, a second mounting member fixedly attached to the pillow and slidably and removably mountable onto the first mounting member, and a hole in the second mounting member coinciding with the membrane area whereby the jet can direct a fluid stream onto the backside of the membrane area. The first and second mounting members, when mounted together and onto the pillow and jet, define a water-tight cavity there between having a jet inlet and a discharge opening whereby spent fluid from the jet is discharged downward into the tub or spa. The mounting members may be sliding members. | 06-04-2009 |