Patent application number | Description | Published |
20090234225 | FLUORESCENCE DETECTION SYSTEM - Exemplary embodiments include systems, methods, and compositions for the intra-operative detection of target tissue. At least one embodiment includes a fluorescence detection instrument that may be used for intra-operative detection of a fluorescent targeting agent, its binding site, and its interaction within cancer tissues. An exemplary embodiment is highly sensitive to the local deposition of fluorescence agents even at a low concentration. In at least one embodiment, the system includes a handheld navigation instrument that is usable to excite, detect, and report the fluorescent deposition of the targeting agent in real-time. In alternative embodiments, the system includes a wearable unit to excite, detect, and visually report the fluorescent deposition of the targeting agent to the user. The wearable unit includes eyewear that allow the user to perform image-guided surgery based on the near real-time fluorescence detection of the fluorescent targeting agent. | 09-17-2009 |
20100249231 | HSP90 Inhibitors of Protein-Protein Interaction HSP90 Chaperone Complexes and Therapeutic Uses Thereof - A novel Hsp90 inhibitor that disrupts protein-protein interaction in a Hsp90 superchaperone complex without blocking ATP binding and methods for treating diseases such as pancreatic cancer are disclosed. | 09-30-2010 |
20110112052 | SPIRO-OXINDOLE MDM2 ANTAGONISTS - Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. | 05-12-2011 |
20120035457 | ELECTROMAGNETIC SYSTEM AND METHOD - Differences of electromagnetic (EM) properties between healthy and cancerous tissues allow detection of abnormal conditions occurring in a tissue of an animal, for example, intra-operative cancer detection. By using a time-varying EM field, electrical eddy currents are generated in the tissue sample, and assessed using phase-sensitive detection. In some aspects, a change in phase shift between the voltage in a receiver coil and the voltage in a driver coil provide a direct and immediate indication of differences in EM properties of specimens. | 02-09-2012 |
20120189539 | BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME - Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed. | 07-26-2012 |
20130243874 | NANOPARTICLES COATED WITH AMPHIPHILIC BLOCK COPOLYMERS - The present provides amphiphilic block copolymer coated surfaces (e.g., nanoparticles, medical devices, etc.) and methods of preparing such surfaces. In certain embodiments, the present invention provides amphiphilic block copolymer coated single dispersed nanoparticles, which are stable in buffer (e.g., PBS) and have neutral but functionable surfaces, and methods of preparing the same. | 09-19-2013 |
20130296303 | SPIRO-OXINDOLE MDM2 ANTAGONISTS - Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. | 11-07-2013 |
20140199234 | BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME - Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed. | 07-17-2014 |
20140256706 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME - Inhibitors of BET bromodomains and compositions containing the same are disclosed. Methods of using the BET bromodomain inhibitors in the treatment of diseases and conditions wherein inhibition of BET bromodomain provides a benefit, like cancers, also are disclosed. | 09-11-2014 |
20140275070 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates generally to thienopyrimidine and thienopyridine class compounds and methods of use thereof. In particular embodiments, the present invention provides compositions comprising thienopyrimidine class compounds and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins (e.g., for the treatment of leukemia, solid cancers and other diseases dependent on activity of MLL1 and MLL2 or menin). | 09-18-2014 |
20140296551 | CONJUGATED GOLD NANOPARTICLES - The present invention relates to methods, compositions, and kits for generating conjugated gold nanoparticles. In certain embodiments, the present invention provides methods of generating unsaturated conjugated gold nanoparticles by mixing naked gold nanoparticles with a first type of attachment molecules at a molar ratio such that the attachment molecules attach to the naked gold particles at a density level below the saturation level of the naked gold particles (e.g., at a saturation level of 1-99%). In some embodiments, a second type of attachment molecules (e.g., with the opposite charge as the first type of attachment molecules) are mixed with the unsaturated conjugated gold nanoparticles to generate double-conjugated gold nanoparticles (e.g., that are zwitterionic) | 10-02-2014 |
20140378680 | SPIRO-OXINDOLE MDM2 ANTAGONISTS - Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. | 12-25-2014 |
20150051534 | PHOTOTHERMAL THERAPY USING MAGNETIC NANOPARTICLES - The present invention provides methods, systems, and devices for performing photothermal therapy (e.g., to treat cancer) using photothermal nanoparticles with a biocompatible coating surrounding a highly crystallized Fe | 02-19-2015 |
20150065858 | CORE-SATELLITE NANOCOMPOSITES FOR MRI AND PHOTOTHERMAL THERAPY - The present invention provides methods, compositions, systems, and kits comprising core-satellite nanocomposites useful for photothermal and/or MRI applications (e.g., tumor treatment and/or imaging). In certain embodiments, the core-satellite nanocomposites comprise: i) a core nanoparticle complex comprising a biocompatible coating surrounding a nanoparticle core, and ii) at least one satellite component attached to, or absorbed to, the biocompatible coating. In some embodiments, the nanoparticle core and satellite component are composed of near-infrared photothermal agent material and/or MRI contrast agent material. In further embodiments, the satellite component is additionally or alternatively composed of near-infrared optical dye material. | 03-05-2015 |
20150246923 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS - The present disclosure provides substituted 9H-pyrimido[4,5-b]indoles and 5H-pyrido[4,3-b]indoles and related analogs represented by Formula I: | 09-03-2015 |
20150336994 | BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME - Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed. | 11-26-2015 |
20160046647 | COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF - The present invention relates generally to thienopyrimidine and thienopyridine class compounds and methods of use thereof. In particular embodiments, the present invention provides compositions comprising thienopyrimidine and thienopyridine class compounds and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins (e.g., for the treatment of leukemia, solid cancers and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin). | 02-18-2016 |
20160058702 | CLEAVABLE POLYMERIC MICELLES - The present invention provides compositions, systems, and methods employing cleavable polymeric micelles. For example, provided herein are compositions comprising micelles that contain a hydrophobic agent (e.g., metal nanoparticles and/or therapeutic agent), where the micelles are formed from a plurality of amphiphilic polymer molecules that comprise a hydrophilic polymer and a hydrophobic polymer, where the hydrophobic polymer comprises a cleavable Furan-Maleimide adduct. Also provided herein are methods of administering such compositions to a subject and treating a localized area of the subject with a device that emits heat, NIR light, and/or alternating magnetic current such that at least some of the micelles inside the subject near the localized area are disrupted (e.g., releasing a therapeutic agent). | 03-03-2016 |
20160090446 | CONJUGATED GOLD NANOPARTICLES - The present invention relates to methods, compositions, and kits for generating conjugated gold nanoparticles. In certain embodiments, the present invention provides methods of generating unsaturated conjugated gold nanoparticles by mixing naked gold nanoparticles with a first type of attachment molecules at a molar ratio such that the attachment molecules attach to the naked gold particles at a density level below the saturation level of the naked gold particles (e.g., at a saturation level of 1-99%). In some embodiments, a second type of attachment molecules (e.g., with the opposite charge as the first type of attachment molecules) are mixed with the unsaturated conjugated gold nanoparticles to generate double-conjugated gold nanoparticles (e.g., that are zwitterionic). | 03-31-2016 |
Patent application number | Description | Published |
20100301589 | PROTECTIVE LAYER FOR AN AIRBAG ASSEMBLY - An instrument panel assembly for a passenger vehicle is provided with a protective film. The protective film has only one unfolded layer. The film layer is sized to cover an opening in an instrument panel. The opening is sized for an airbag to deploy through. The film layer is provided with a slit for separating into portions. The portions extend through the instrument panel as the airbag deploys. The protective film prevents the airbag from being damaged. The film layer also prevents the airbag from damaging the instrument panel. The instrument panel may be provided with a door for selectively covering the opening. The instrument panel assembly may include a hinge for pivotally connecting the door to the instrument panel. | 12-02-2010 |
20110204608 | ENERGY ABSORBING STRUCTURE FOR VEHICLE KNEE BOLSTER COVER - An energy absorbing panel assembly for the interior of a motor vehicle is disclosed. The energy absorbing panel assembly, typically the knee bolster panel adjacent the steering wheel, includes an energy absorbing structure integrally molded to the panel. The energy absorbing structure includes three outer side walls and a top wall. The outer side walls extend from the same side of the top wall to the panel. Extending from the top wall to the panel is at least one top wall supporting rib. The rib is positioned between the outer side walls. Ordinarily at least two such ribs will be provided. At least one of the outer walls is at an obtuse angle relative to the plane of the top wall. All three of the outer walls may be at an obtuse angle relative to the plane of the top wall. In addition to the one or more ribs extending from the top wall to the panel between the outer side walls one or more outer wall-supporting ribs may also be provided extending between the outer side walls and intersecting the top wall supporting rib. Lateral supports may be provided between the outer side walls and the panel. | 08-25-2011 |
20120032365 | FOAMED RESIN INJECTION MOLDING APPARATUS AND METHOD - An injection molding apparatus and method are provided. The method includes a molded cavity coupled to a resin injection apparatus which injects molten resin under pressure with a gas such that the resin foams within the mold cavity. An electrical heater is in contact with a first cavity surface, and a cooling medium cools the mold. The resin may include metallic flakes. | 02-09-2012 |
20120235436 | ONE-PIECE DECORATIVE TRIM BEZEL HAVING PLURAL UNPAINTED FINISHES - A one-piece trim bezel formed from multiple components. In the event of two co-molded components, the first co-molded part is composed of a polymerized material having an unpainted surface that may be a high gloss smooth surface or a textured low gloss surface and the second co-molded part, formed with the first part, is composed of a plateable plastic material. The second co-molded part is co-molded with the said first co-molded part to form a single piece trim bezel. The color of the polymerized material of the first co-molded part may be selected from a variety of colors. The plateable plastic material may be plateable with chrome. A multiple-shot injection molding process is used to form the one-piece trim bezel which joins the first co-molded part and the second co-molded part in one operation. The formed part is then subjected to a plating process during which time the chrome only deposits on the surface of the plateable plastic material of the second co-molded part while the surface of the first co-molded part remains unplated. | 09-20-2012 |
20140117579 | ONE-PIECE DECORATIVE TRIM BEZEL HAVING PLURAL UNPAINTED FINISHES - A one-piece trim bezel formed from multiple components. In the event of two co-molded components, the first co-molded part is composed of a polymerized material having an unpainted surface that may be a high gloss smooth surface or a textured low gloss surface and the second co-molded part, formed with the first part, is composed of a plateable plastic material. The plateable plastic material may be plateable with chrome. A multiple-shot injection molding process is used to form the one-piece trim bezel which joins the first co-molded part and the second co-molded part in one operation. The formed part is then subjected to a plating process during which time the chrome only deposits on the surface of the plateable plastic material of the second co-molded part while the surface of the first co-molded part remains unplated. | 05-01-2014 |
20150336315 | GAS REMOVAL VACUUM SYSTEM FOR USE WITH MOLD-IN-COLOR TOOLING - An injection molding tool for molded-in-color injection molding is disclosed. The tool includes a first mold half that includes a mold cavity, a second molding half that includes a molding core, an ejector pin fluidly associated with the first mold half, and a gas removal vacuum system fluidly associated with the ejector pin. The first mold half and the second mold half meet at a parting line that is free of vents. In operation, the two halves are brought together, defining a mold cavity therebetween. The gas removal vacuum system is activated to remove any air that is trapped between the two halves. Once the trapped air has been removed, an article-forming, polymerizable resin is injected into the mold cavity. The gas removal vacuum system is again operated to remove gas generated by the polymerizable resin during the injection process. | 11-26-2015 |
Patent application number | Description | Published |
20090077968 | Turbocharged Engine Control Operation with Adjustable Compressor Bypass - A method of operating an engine having a turbocharger and a high pressure EGR system is provided. In one example, a compressor of the turbocharger may have a recirculation passage with a recirculation valve coupled therein. The method may include during a first engine airflow condition: delivering at least some high pressure un-cooled EGR to the intake, downstream of the compressor, operating the throttle at a first throttle amount, and operating the compressor bypass valve at a first bypass amount to increase exhaust gas temperature; and during a second engine airflow condition higher than the first engine airflow: delivering at least some high pressure cooled EGR to the intake, downstream of the compressor, operating the throttle at a second throttle amount more open than the first amount, and operating the compressor bypass valve at a second bypass amount more closed than the first amount. | 03-26-2009 |
20090249773 | Diesel Turbine SCR Catalyst - A system for treating exhaust gases from an engine is described. The system includes, the exhaust gases routed from the engine to atmosphere through an exhaust passage, the system comprising: an injector directing a spray of reductant into the exhaust gases routed from the engine to atmosphere; an exhaust separation passage that separates an exhaust gas flow received from the engine into a plurality of separate exhaust gas flows; a plurality of oxidation catalysts, each of which receives one of the plurality of separate exhaust gas flows; a flow combining passage that receives the plurality of separate exhaust gas flows and combines them into a re-combined exhaust gas flow; a turbocharger that receives the re-combined exhaust gas flow from the flow combining passage; and a selective catalytic reduction catalyst positioned downstream of the turbocharger. | 10-08-2009 |
20090293477 | TRANSIENT COMPRESSOR SURGE RESPONSE FOR A TURBOCHARGED ENGINE - A method for responding to an existing or incipient surge condition of a turbocharger coupled to an engine of a motor vehicle is provided. The method comprises receiving a signal responsive to an operating condition of the turbocharger and adjusting one or more operating parameters of the motor vehicle when a power of the signal, integrated over a pre-selected range of non-zero frequencies, exceeds a pre-selected threshold. Other embodiments provide related systems for responding to an existing or incipient surge condition of a turbocharger. | 12-03-2009 |
20110173975 | Turbocharger - In one example, a turbocharger for an internal combustion engine is described. The turbocharger comprises a casing containing an impeller having a full blade coupled to a hub that rotates about an axis of rotation. The casing includes a bleed port and an injection port. The full blade includes a hub edge, a casing edge, and a first distribution of angles, each angle measured between the axis of rotation and a mean line at the hub edge at a meridional distance along the hub edge. The full blade includes a second distribution of angles, each angle measured between the axis of rotation and a mean line at the casing edge at a meridional distance along the casing edge. Further, various systems are described for affecting the aerodynamic properties of the compressor and turbine components in a way that may extend the operating range of the turbocharger. | 07-21-2011 |
20110247327 | Diesel Turbine SCR Catalyst - A system for treating exhaust gases from an engine is described. The system includes, the exhaust gases routed from the engine to atmosphere through an exhaust passage, the system comprising: an injector directing a spray of reductant into the exhaust gases routed from the engine to atmosphere; an exhaust separation passage that separates an exhaust gas flow received from the engine into a plurality of separate exhaust gas flows; a plurality of oxidation catalysts, each of which receives one of the plurality of separate exhaust gas flows; a flow combining passage that receives the plurality of separate exhaust gas flows and combines them into a re-combined exhaust gas flow; a turbocharger that receives the re-combined exhaust gas flow from the flow combining passage; and a selective catalytic reduction catalyst positioned downstream of the turbocharger. | 10-13-2011 |
20120198843 | REGENERATIVE ASSISTED TURBOCHARGER SYSTEM - A turbocharged internal combustion engine having an engine control unit and apparatus coupled to the turbocharger, to assist in acceleration of the turbocharger in response to an acceleration signal from the engine control system and to decelerate the turbocharger in response a deceleration signal from the engine control unit. The apparatus absorbs energy from the turbocharger in response to the deceleration signal from the engine control unit to decelerate the turbocharger. The apparatus includes one or more hydraulic wheels on the same shaft of, and between, the turbine and compressor of the turbocharger, the one or more hydraulic wheels being driven in response to the acceleration signal to assist in acceleration of the turbocharger or absorb energy from the turbocharger shaft in response the deceleration signal. | 08-09-2012 |
20130004292 | CONTROL STRATEGY FOR DECREASING RESONANCE IN A TURBOCHARGER - A method for operation of an engine including a turbocharger system is provided. The method includes adjusting turbocharger rotational acceleration or deceleration in response to one or more resonant frequencies. Additionally in some examples, the method may further include increasing turbocharger rotation in response to one or more resonant frequencies during a first condition, and increasing turbocharger deceleration in response to one or more resonant frequencies during a second condition, the second condition different from the first condition. In this way, it is possible to enhance the useful life cycle of the turbocharger and associated engine by limiting the operating time in a resonant frequency band. | 01-03-2013 |
20130013168 | TRANSIENT COMPRESSOR SURGE RESPONSE FOR A TURBOCHARGED ENGINE - A method for responding to an existing or incipient surge condition of a turbocharger coupled to an engine of a motor vehicle is provided. The method comprises receiving a signal responsive to an operating condition of the turbocharger and adjusting one or more operating parameters of the motor vehicle when a power of the signal, integrated over a pre-selected range of non-zero frequencies, exceeds a pre-selected threshold. Other embodiments provide related systems for responding to an existing or incipient surge condition of a turbocharger. | 01-10-2013 |
20130042608 | SLIDING VANE GEOMETRY TURBINES - Various systems and methods are described for a variable geometry turbine. In one example, a turbine nozzle comprises a central axis and a nozzle vane. The nozzle vane includes a stationary vane and a sliding vane. The sliding vane is positioned to slide in a direction substantially tangent to an inner circumference of the turbine nozzle and in contact with the stationary vane. | 02-21-2013 |
20140060009 | SECONDARY AIR INTRODUCTION SYSTEM AND METHOD FOR SYSTEM OPERATION - A vehicle system operation method is provided. The method comprises, during a first operating condition, increasing back pressure in a first exhaust conduit positioned upstream of a turbine and downstream of a first emission control device and during a second operating condition, reducing back pressure in the first exhaust conduit and flowing boosted air from downstream of a compressor into a second exhaust conduit positioned upstream of a second emission control device and downstream of the turbine. | 03-06-2014 |
20140360160 | VARIABLE GEOMETRY TURBINE VANE - Embodiments may provide variable geometry turbine, a nozzle vane for a variable geometry turbine, and a method. The variable geometry turbine that may include a turbine wheel and a plurality of adjustable vanes radially positioned around the turbine wheel. The turbine may also include a flow disrupting feature on one or more outside surfaces of one or more of the plurality of adjustable vanes. | 12-11-2014 |
20140377051 | TURBOCHARGER - Systems and methods are disclosed for a turbocharger compressor, the system comprising: an actuatable annular disk comprising choke slots therein; an outer annular disk comprising choke slots therein; and an actuator to rotate the actuatable annular disk relative to the outer annular disk to vary alignment of the choke slots of the actuatable annular disk and the outer annular disk. The actuator may be controlled by an engine controller responsive to operating conditions of the compressor and actuated to align choke slots. Alignment of the choke slots allows air to be drawn into the impeller effectively expanding the compressor flow capacity to prevent compressor choke. | 12-25-2014 |
20160102579 | SHEET METAL TURBINE HOUSING WITH CELLULAR STRUCTURE REINFORCEMENT - Systems are provided for a reinforcement element coupled to a sheet metal turbine housing that imparts desirable thermal-protective and structurally strengthening characteristics to the housing layers. In one example, a system may include a turbine comprising a housing surrounding a turbine rotor, the housing having an outer layer surrounding an inner layer at a distance to form an intermediate space between the inner and outer layers. Moreover, disposed in the intermediate space is a reinforcement element coupled to the inner and outer layers, providing strength and consistent rigidity without a significant increase in weight to the housing. | 04-14-2016 |
Patent application number | Description | Published |
20080245070 | Method and system to operate diesel engine using real time six dimensional empirical diesel exhaust pressure model - A method to estimate real-time exhaust pressure in a compression ignition engine with variable geometry turbocharger and an EGR by adding the turbocharger RPM, the engine RPM, EGR value position and intake manifold pressure to determine a final turbocharger turbine inlet pressure to control NOx emissions. | 10-09-2008 |
20090158706 | VARIABLE ENGINE OUT EMISSION CONTROL ROADMAP - A method for operating an internal combustion engine for variable engine out NOx control talking into account the age of the SCR. | 06-25-2009 |
20090165544 | System and Method for Determining Non-Sensed Vehicle Operating Parameters - A method and system is provided for determining non-sensed vehicle operating parameters of a vehicle system. The method and system further provide for determining an engine air mass flow rate using the non-sensed vehicle operating parameters. A plurality of vehicle operating set-points may be determined using the non-sensed vehicle system operating parameters and the non-sensed engine air mass flow rate. A controller may use the vehicle operating set-points in order to control emissions of the vehicle system. | 07-02-2009 |
20100281855 | MODEL BASED METHOD FOR SELECTIVE CATALYST REDUCER UREA DOSING STRATEGY - A method to control NO | 11-11-2010 |
20100326052 | METHOD FOR MONITORING AMMONIA STORAGE IN AN EXHAUST AFTERTREATMENT SYSTEM - A method for monitoring the ammonia-selective catalyst reduction device includes monitoring states of parameters of the exhaust gas feedstream upstream of the ammonia-selective catalyst reduction device, analytically segmenting the ammonia-selective catalyst reduction device into a plurality of discrete substrate elements, sequentially calculating a change in ammonia storage for each of the discrete substrate elements, and determining a total ammonia storage concentration on the ammonia-selective catalyst reduction device based upon the sequentially calculated change in ammonia storage for each of the discrete substrate elements. | 12-30-2010 |
20110173955 | METHOD AND APPARATUS FOR MONITORING A PARTICULATE FILTER - A method to monitor a particulate filter includes determining an equivalent bypass area corresponding to a difference between a mass flowrate of an exhaust gas feedstream flowing to the particulate filter and a mass flowrate of the exhaust gas feedstream flowing through porous walls of a substrate. | 07-21-2011 |
20120060469 | MODEL-BASED DIAGNOSTIC METHOD AND SYSTEM FOR A SELECTIVE REDUCTION CATALYST DEVICE IN A VEHICLE - A vehicle includes an engine, an exhaust system having a selective catalytic reduction (SCR) device, a NOx sensor, and first and second controllers. The first controller compares estimated NOx levels from an SCR model to actual levels from the sensor, and updates the SCR model when the values differ from each other. The second controller evaluates an updating frequency of the SCR model, and executes a control action when the frequency is excessive. A control system includes the sensor and two controllers noted above. A method of diagnosing the exhaust system includes measuring NOx gasses downstream of the SCR device, updating the SCR model when the deviation is present between estimated and measured NOx levels, comparing estimated ammonia (NH | 03-15-2012 |
20120285140 | METHOD FOR MONITORING HYDROCARBON SLIP FROM AN OXIDATION CATALYST - A method for operating a compression-ignition internal combustion engine including an exhaust aftertreatment system having an oxidation catalyst fluidly coupled upstream of a catalyzed particulate filter includes introducing fuel into an exhaust gas feedstream of the engine upstream of the oxidation catalyst, determining operating parameters associated with the exhaust gas feedstream, determining a hydrocarbon slip rate through the oxidation catalyst corresponding to the operating parameters associated with the exhaust gas feedstream and the introduced fuel into the exhaust gas feedstream, and controlling a flowrate of fuel introduced into the exhaust gas feedstream upstream of the oxidation catalyst in response to the estimated hydrocarbon slip rate through the oxidation catalyst. | 11-15-2012 |
20120285143 | METHOD FOR MANAGING AMMONIA SLIP - An internal combustion engine is configured to operate in a compression-ignition combustion mode and includes an exhaust aftertreatment system having an ammonia-selective catalytic reduction device. A method for operating the engine includes determining a present engine NOx generation rate, determining a NOx reduction rate of the ammonia-selective catalytic reduction device, determining an ammonia slip rate from the ammonia-selective catalytic reduction device corresponding to the NOx reduction rate of the ammonia-selective catalytic reduction device and the present engine NOx generation rate, and controlling engine operation to adjust the present engine NOx generation rate in response to the ammonia slip rate from the ammonia-selective catalytic reduction device. | 11-15-2012 |
20120297750 | METHOD FOR MONITORING AN EXHAUST PARTICULATE FILTER - An exhaust aftertreatment system having a particulate filter is monitored by monitoring a particulate filter regeneration event and detecting an associated regeneration period. The particulate filter regeneration period is compared to a preferred event window. A fault is detected when the monitored particulate filter regeneration period extends beyond the preferred event window. | 11-29-2012 |
20120297751 | METHOD FOR DETERMINING LOAD OF A PARTICULATE FILTER - A particulate filter is monitored for a particulate matter load when fluidly coupled to an internal combustion engine. Monitoring of the particulate filter is achieved by determining a rate of production of particulate matter from the internal combustion engine, a rate of capture of the particulate matter within the particulate filter, a regeneration rate for the particulate filter, and an amount of particulate matter collected in the particulate filter. | 11-29-2012 |
20120311998 | SYSTEM AND METHOD FOR DETERMINING AN AMMONIA GENERATION RATE IN A THREE-WAY CATALYST - A system according to the principles of the present disclosure includes a rate determination module, a storage level determination module, and an air/fuel ratio control module. The rate determination module determines an ammonia generation rate in a three-way catalyst based on a reaction efficiency and a reactant level. The storage level determination module determines an ammonia storage level in a selective catalytic reduction (SCR) catalyst positioned downstream from the three-way catalyst based on the ammonia generation rate. The air/fuel ratio control module controls an air/fuel ratio of an engine based on the ammonia storage level. | 12-13-2012 |
20130025261 | SYSTEM AND METHOD FOR CONTROLLING AMMONIA LEVELS IN A SELECTIVE CATALYTIC REDUCTION CATALYST USING A NITROGEN OXIDE SENSOR - A system according to the principles of the present disclosure includes an air/fuel ratio determination module and an emission level determination module. The air/fuel ratio determination module determines an air/fuel ratio based on input from an air/fuel ratio sensor positioned downstream from a three-way catalyst that is positioned upstream from a selective catalytic reduction (SCR) catalyst. The emission level determination module selects one of a predetermined value and an input based on the air/fuel ratio. The input is received from a nitrogen oxide sensor positioned downstream from the three-way catalyst. The emission level determination module determines an ammonia level based on the one of the predetermined value and the input received from the nitrogen oxide sensor. | 01-31-2013 |
20130125529 | METHOD FOR CONTROLLING REGENERATION WITHIN AN AFTER-TREATMENT COMPONENT OF A COMPRESSION-IGNITION ENGINE - A method for controlling regeneration within an after-treatment component of a compression-ignition engine comprises calculating an initial estimate of accumulated particulate matter based on a pressure-based soot accumulation model and a pressure drop index indicative of a decrease in pressure across the component. An adjusted estimate of accumulated particulate matter in the component is calculated based on the initial estimate and a soot prediction error inherent in the soot model. The adjusted estimate is compared to a predetermined threshold associated with the after-treatment component, and a remedial action is initiated when the adjusted estimate of accumulated particulate matter in the after-treatment component exceeds the predetermined threshold. The pressure-based soot accumulation model may be configured to predict soot accumulation in the absence of passive regeneration, and an adjusted kinetic burn model may be used to estimate a quantity of soot disposed through passive regeneration. | 05-23-2013 |
20130263575 | SYSTEM AND METHOD FOR CONTROLLING AN EXHAUST SYSTEM HAVING A SELECTIVE CATALYST REDUCTION COMPONENT - A method for controlling operation of an SCR component includes receiving a signal reflecting a sensed condition of an exhaust stream associated with the SCR component, estimating an apparent aging time of the SCR component based on the sensed condition of the exhaust stream, and setting an operating condition of the SCR component based on the apparent aging time of the SCR component. | 10-10-2013 |
20130311065 | SYSTEM AND METHOD FOR CONTROLLING AN ENGINE BASED ON AMMONIA STORAGE IN MULTIPLE SELECTIVE CATALYTIC REDUCTION CATALYSTS - A system according to the principles of the present disclosure includes a storage estimation module and an air/fuel ratio control module. The storage estimation module estimates a first amount of ammonia stored in a first selective catalytic reduction (SCR) catalyst and estimates a second amount of ammonia stored in a second SCR catalyst. The air/fuel ratio control module controls an air/fuel ratio of an engine based on the first amount, the second amount, and a temperature of a substrate disposed in the second SCR catalyst. | 11-21-2013 |
20140013725 | KINETICS-BASED SCR CONTROL MODEL IMPROVEMENT - A method for monitoring a discrete substrate element from an ammonia-selective catalyst reduction device configured to treat an exhaust gas feedstream of an internal combustion engine includes monitoring amounts of ammonia that are adsorbed, desorbed, and oxidized and an amount of ammonia that is consumed in reducing NOx in the exhaust gas feedstream from the discrete substrate element. An amount of ammonia consumption for the discrete substrate element is determined based on the amount of ammonia that is oxidized and the amount of ammonia that is consumed in reducing NOx in the exhaust gas feedstream. The amount of ammonia that is adsorbed and the amount of ammonia that is desorbed for the discrete substrate element are compared and the amount of ammonia consumption for the discrete substrate element is adjusted when the amount of ammonia that is adsorbed is less than the amount of ammonia that is desorbed. | 01-16-2014 |
20140123608 | ENGINE-OUT SOOT FLOW RATE PREDICTION - A method for engine-out soot flow rate prediction of an exhaust gas treatment system is provided. A measured level of oxides of nitrogen in the exhaust gas treatment system is received. An engine fuel injection timing and air-fuel ratio of an engine producing the oxides of nitrogen are also received. An engine timing factor is determined based on the engine fuel injection timing. An engine air-fuel ratio factor is determined based on the engine air-fuel ratio. An engine-out soot flow rate prediction is generated based on the measured level of oxides of nitrogen, the engine timing factor, and the engine air-fuel ratio factor. | 05-08-2014 |
20140338434 | ADAPTIVE SOOT MASS ESTIMATION IN A VEHICLE EXHAUST AFTER-TREATMENT DEVICE - A method of estimating a total amount of soot in a diesel particulate filter includes monitoring a pressure differential across the diesel particulate filter; monitoring an engine speed and an engine load from an engine in fluid communication with the diesel particulate filter; determining a first soot mass estimate from the monitored pressure differential, the first soot mass estimate having an associated confidence indicator based on the monitored engine speed and engine load; determining a second soot mass estimate from the monitored engine speed and engine load; and outputting the first soot mass estimate if the confidence indicator is above a predetermined threshold, and outputting the second soot mass estimate if the confidence indicator is below the predetermined threshold. | 11-20-2014 |
20140360165 | SELECTIVE CATALYTIC REDUCTION DEVICE MONITORING SYSTEM - A selective catalytic reduction (SCR) device monitoring system includes an engine out NOx monitoring module, an SCR out NOx monitoring module configured and disposed to monitor NOx released from the SCR device, and a NOx storage model module operatively connected to the engine out NOx module and the SCR out NOx monitoring module. The NOx storage model module is configured and disposed to determine an amount of NOx stored in the SCR device. A consumed ammonia correction model module is operatively coupled to the NOx storage model module and configured and disposed to calculate a corrected consumed ammonia prediction factor. | 12-11-2014 |
20150040543 | METHOD AND SYSTEM FOR IDENTIFYING A SOURCE OF NITROGEN OXIDE REDUCTION INEFFICIENCY - System and methods can identify a source of nitrogen oxide reduction inefficiency in an exhaust system including first and second selective catalytic reduction (SCR) catalysts connected in series along an exhaust line. The methods and systems can determine which of the first and second SCR catalysts is a source of nitrogen oxide reduction inefficiency based on the temperatures of the exhausts gases flowing through the first and second SCR catalysts. | 02-12-2015 |
20150088398 | EXHAUST SYSTEM AND METHOD OF ESTIMATING DIESEL PARTICULATE FILTER SOOT LOADING FOR SAME USING TWO-TIER NEURAL NETWORK - A method of estimating soot loading in a diesel particulate filter (DPF) in a vehicle exhaust system includes estimating an engine-out soot rate using a first neural network that has a first set of vehicle operating conditions as inputs. The method further includes estimating DPF soot loading using a second neural network that has the estimated engine-out soot rate from the first neural network and a second set of vehicle operating conditions as inputs. Estimating the engine-out soot rate and estimating the DPF soot loading are performed by an electronic controller that executes the first and the second neural networks. The method also provides for training the first and second neural networks both offline (for initial settings of the neural networks in the vehicle), and online (when the vehicle is being used by a vehicle operator). An exhaust system has a controller that implements the method. | 03-26-2015 |
20150088399 | EXHAUST SYSTEM AND METHOD OF ESTIMATING DIESEL PARTICULATE FILTER SOOT LOADING FOR SAME - A method of estimating soot loading in a diesel particulate filter (DPF) in a vehicle exhaust system includes determining engine operating conditions of an engine in exhaust flow communication with the diesel particulate filter, and monitoring a pressure differential of the exhaust flow across the diesel particulate filter. The method includes estimating soot loading in the diesel particulate filter according to a pressure-based model using the monitored pressure differential when the engine operating conditions are within a predetermined first set of engine operating conditions, and estimating soot loading in the diesel particulate filter according to an engine-out soot model and a DPF soot loading model when the engine operating conditions are within a predetermined second set of operating conditions. The method includes updating the engine-out soot model based in part on a difference in estimated soot loading between the pressure-based model and the DPF soot loading model. | 03-26-2015 |
20150209729 | METHOD OF ESTIMATING HYDROCARBON STORAGE IN A CATALYTIC DEVICE - A method of estimating hydrocarbon storage in a catalytic device of an exhaust gas treatment system includes calculating an amount of hydrocarbons absorbed in the catalytic device per unit volume of exhaust gas over a period of time, calculating an amount of hydrocarbons desorbed in the catalytic device per unit volume of exhaust gas over the period of time, and calculating an amount of hydrocarbons oxidized in the catalytic device per unit volume of exhaust gas over the period of time. The amount of hydrocarbons oxidized in the catalytic device and the amount of hydrocarbons desorbed in the catalytic device are subtracted from the amount of hydrocarbons absorbed in the catalytic device to determine the amount of hydrocarbons stored in the catalytic device. | 07-30-2015 |
20150211962 | METHOD OF ESTIMATING SOOT OUTPUT FROM AN ENGINE - A method of estimating a current soot output from an engine includes sensing a mass flow rate of a flow of exhaust gas from the engine, and defining a soot output base rate of the engine when the engine is operating at a reference state. A soot ratio for a current operating state of the engine is calculated. The mass flow rate, the soot output base rate, and the soot ratio are multiplied together to define an estimated value of the current soot output from the engine. The soot ratio is based on current engine operating parameters, including an air/fuel ratio of the engine, an exhaust gas recirculation ratio of the engine, a fuel injection pressure of the engine, and a fuel injection timing of the engine. | 07-30-2015 |
20150252709 | SYSTEM AND METHOD FOR CONTROLLING DOSING IN SELECTIVE CATALYTIC REDUCTION CATALYST - An engine assembly includes an exhaust system having a first SCR catalyst, a second SCR catalyst in fluid communication with the first SCR catalyst, and an injector configured to inject reductant into the exhaust system. A controller is configured to estimate a first amount of ammonia stored in the first SCR catalyst and to estimate a second amount of ammonia stored in the second SCR catalyst. The controller is operatively connected to the injector and configured to control the amount of reductant injected by the injector. The controller controls the injector based on the first amount, the second amount, and a temperature of a substrate disposed in the second SCR catalyst. | 09-10-2015 |
20150267590 | SYSTEM TO MONITOR REGENERATION FREQUENCY OF PARTICULATE FILTER - An exhaust treatment system to treat exhaust gas includes a particulate filter configured to trap soot contained in the exhaust gas, and a pressure sensor that outputs a pressure signal indicative of a pressure differential of the particulate filter. A soot mass module is configured to determine a soot mass indicative of an amount of soot stored in the particulate filter based on the pressure differential. The soot mass is selectively determined according to a first soot model or a second soot model. An adaptation soot load module corrects the first soot model based on the second soot model such that the first soot model is adapted to the second soot model. A frequency regeneration module determines an actual rate at which the first soot model is corrected. The frequency regeneration module further determines the particulate filter is excessively regenerated based on the actual rate and a threshold. | 09-24-2015 |
20150354428 | METHOD OF ESTIMATING ENGINE-OUT NOx MASS FLOW RATE - A method of estimating a mass flow rate of nitrogen oxides in exhaust gas includes sensing a mass flow rate of a flow of exhaust gas from the engine. A nitrogen oxides base concentration for when the engine is operating at a reference state is defined, and a nitrogen oxides ratio for a current operating state of the internal combustion engine is calculated. The mass flow rate of the flow of exhaust gas, the nitrogen oxides base concentration, and the nitrogen oxides ratio for the current operating state of the engine are multiplied together to define an estimated value of the current mass flow rate of nitrogen oxides in the flow of exhaust gas from the engine. The estimated value of the mass flow rate of nitrogen oxides may be compared to the output from a nitrogen oxides sensor to determine proper functionality of the nitrogen oxides sensor. | 12-10-2015 |
20160097314 | METHOD AND APPARATUS FOR ESTIMATING NITROGEN OXIDES OUT OF AN ENGINE - A system is provided and includes a fuel module that, based on a crankshaft angle of an engine, generates a value indicative of an amount of fuel burned in a cylinder or a change in the amount of fuel burned. A heat release module, based on the value, determines an amount of heat released during a combustion event of the cylinder. A pressure module, based on the amount of heat released, estimates a pressure in the cylinder. A temperature module, based on the pressure, estimates a temperature in the cylinder. A concentration module, based on the pressure or the temperature, estimates nitrogen oxide concentration levels in the cylinder. An output module, based on the nitrogen oxide concentration levels, estimates an amount of nitrogen oxides. A control module, based on the amount of nitrogen oxides out of the cylinder, controls operation of the engine or an exhaust system. | 04-07-2016 |
Patent application number | Description | Published |
20080289726 | COLD ROLLED, DUAL PHASE, STEEL SHEET AND METHOD OF MANUFACTURING SAME - A steel sheet having (a) a dual phase microstructure with a martensite phase and a ferrite phase and (b) a composition containing by percent weight: 0.01% to 0.2% C; 0.3% to 3% Mn; 0.05% to 2% Si; 0.1% to 2% Cr; 0.01% to 0.10% Al; and 0.0005% to 0.01% Ca, with the balance of the composition being iron and incidental ingredients. Also, the steel sheet is made by a batch annealing method, and has a tensile strength of at least approximately 400 MPa and an n-value of at least approximately 0.175. | 11-27-2008 |
20090071574 | COLD ROLLED DUAL PHASE STEEL SHEET HAVING HIGH FORMABILITY AND METHOD OF MAKING THE SAME - A steel sheet having (a) a dual phase microstructure with a martensite phase and a ferrite phase and (b) a composition containing by percent weight: 0.01≦C≦0.2; 0.3≦Mn≦3; 0.05≦Si≦2; 0.2≦Cr+Ni≦2; 0.01≦Al≦0.10; 0.0005≦Ca≦0.01, with the balance of the composition being iron and incidental ingredients. Also, the steel sheet is made by a batch annealing method, and has a tensile strength of at least approximately 400 megapascals and an n-value of at least approximately 0.175. | 03-19-2009 |
20090071575 | HOT ROLLED DUAL PHASE STEEL SHEET, AND METHOD OF MAKING THE SAME - A hot rolled steel sheet having a dual phase microstructure with a martensite phase of less than 35% by volume and a ferrite phase of more than 50% by volume and a composition containing by percent weight: 0.01≦C≦0.2; 0.3≦Mn≦3; 0.2≦Si≦2; 0.2≦Cr+Ni≦2; 0.01≦Al≦0.10; Mo less than about 0.2%, 0.0005≦Ca≦0.01, with the balance iron and incidental ingredients. Hot rolled sheet for cold rolling, the silicon range may be from about 0.05% to about 2%, and the amount of molybdenum may be up to 0.5%. Also, the hot rolled steel sheet has a tensile strength of at least 500 megapascals, a hole expansion ratio more than about 50%, and. a yield strength/tensile strength ratio less than 70%. | 03-19-2009 |
20090098408 | COMPLEX METALLOGRAPHIC STRUCTURED STEEL AND METHOD OF MANUFACTURING SAME - A multi-phase steel sheet having microstructure having in combination ferrite, martensite of between 3% and 65% by volume, and at least one microstructure selected from the group consisting of, bainite and retained austenite, and having fine complex precipitates selected from the group of TiC, NbC, TiN, NbN, (Ti.Nb)C, (Ti.Nb)N, and (Ti.Nb)(C.N) particles having at least 50% smaller than 20 nm in size, and physical properties having tensile strength greater than about 780 megapascals and at least one of the properties of elongation greater than about 10%, yield ratio greater than about 70%, and hole expansion ratio greater than about 50%. | 04-16-2009 |
20100043925 | HIGH STRENGTH, HOT DIP COATED, DUAL PHASE, STEEL SHEET AND METHOD OF MANUFACTURING SAME - A galvanized steel sheet having (a) a dual phase microstructure with a martensite phase and a ferrite phase and (b) a composition containing by percent weight: carbon in a range from about 0.01% to about 0.18%; manganese in a range from about 0.2% to about 3%; silicon ≦about 1.2%; aluminum in a range from about 0.01% to about 0.1%; one or both of chromium and nickel in a range from about 0.1% to about 3.5%; calcium in a range from about 0.0003% to about 0.01%; phosphorus ≦about 0.01%; sulfur ≦about 0.03%; nitrogen ≦about 0.02%; molybdenum ≦about 1%; copper ≦about 0.8%; one or more of niobium, titanium, and vanadium ≦about 1%; and boron ≦about 0.006% by weight; and with the balance of the composition being iron and incidental ingredients. In one embodiment, the steel sheet is both galvanized and galvannealed. | 02-25-2010 |
20120018059 | METHOD OF MAKING HOT ROLLED DUAL PHASE STEEL SHEET - A method of making hot rolled steel sheet having a dual phase microstructure with a martensite phase of less than 35% by volume and a ferrite phase of more than 50% by volume and a composition containing by percent weight: 0.01≦C≦0.2; 0.3≦Mn≦3; 0.2≦Si≦2; 0.2≦Cr+Ni≦2; 0.01≦Al≦0.10; Mo less than about 0.2%, 0.0005≦Ca≦0.01, with the balance iron and incidental ingredients. Hot rolled sheet for cold rolling, the silicon range may be from about 0.05% to about 2%, and the amount of molybdenum may be up to 0.5%. Also, the hot rolled steel sheet has a tensile strength of at least 500 megapascals, a hole expansion ratio more than about 50%, and a yield strength/tensile strength ratio less than 70%. | 01-26-2012 |
20120138194 | HIGH STRENGTH, HOT DIP COATED, DUAL PHASE, STEEL SHEET AND METHOD OF MANUFACTURING SAME - A galvanized dual phase steel sheet with a martensite phase and a ferrite phase and a composition containing within the following ranges by weight: carbon from about 0.01% to about 0.18%; manganese from about 0.2% to about 3%; silicon≦about 1.2%; aluminum from about 0.01% to about 0.1%; one or both of chromium and nickel from about 0.1% to about 3.5%; calcium from about 0.0003% to about 0.01%; phosphorus≦about 0.1%; sulfur≦about 0.03%; nitrogen≦about 0.02%; molybdenum≦about 1%; one or more of niobium and titanium≦about 1%; and boron≦about 0.006% by weight; and with the balance of the composition being iron and incidental ingredients. The steel sheet may be both galvanized and galvannealed. | 06-07-2012 |
20130136950 | COMPLEX METALLOGRAPHIC STRUCTURED HIGH STRENGTH STEEL AND METHOD OF MANUFACTURING - A multi-phase steel sheet having microstructure having in combination ferrite, martensite of between 3% and 65% by volume, and at least one microstructure selected from the group consisting of, bainite and retained austenite, and having fine complex precipitates selected from the group of TiC, NbC, TiN, NbN, (Ti.Nb)C, (Ti.Nb)N, and (Ti.Nb)(C.N) particles having at least 50% smaller than 20 nm in size, and physical properties having tensile strength greater than about 780 megapascals and at least one of the properties of elongation greater than about 10%, yield ratio greater than about 70%, and hole expansion ratio greater than about 50%. | 05-30-2013 |