Fuganti
Claudio Fuganti, Milano IT
Claudio Fuganti, Garbagnate Milanese IT
Patent application number | Description | Published |
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20080287693 | Process for the Preparation of 1-Naphthol Mixed Ethers and Intermediates of Crystalline Forms of (+) and (-)-Duloxetine - The invention relates to a process for the preparation of duloxetine (1a), comprising the reaction between 1-fluoronaphthalene and 3-N,N-dimethylamino-1-(2-thienyl)-propan-1-ol in the presence of 1,3-dimethyl-2-oxo-hexahydropyrimidine (DMPU) as the solvent; a method for the identification of duloxetine enantiomers and for the determination of its optical purity is also disclosed. | 11-20-2008 |
Claudio Fuganti, Rodano (mi) IT
Patent application number | Description | Published |
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20110230541 | PROCESS FOR THE PREPARATION OF ROTIGOTINE - A process for the preparation of Rotigotine (I) and of pharmaceutically acceptable salts thereof, which comprises the reductive amination of an amine of formula 6 with the 2-thienylacetic acid-sodium boron hydride complex and which makes use of hydrobromide 5 as an intermediate (II) The process is advantageous from the industrial point of view in that it allows to obtain Rotigotine with high enantiomeric purity starting from optically active 5,6,7,8-tetrahydro-6-(S)-N-propylamino-1-methoxy-naphthalene (2), avoiding the use of dangerous reactives, the need for difficult chromatographic separation or the formation of by-products. Furthermore, two novel crystalline forms are disclosed. | 09-22-2011 |
20130317255 | PROCESS FOR THE PREPARATION OF ROTIGOTINE - A process for the preparation of Rotigotine (1) | 11-28-2013 |
20130345283 | PROCESS FOR THE PREPARATION OF ROTIGOTINE - A process for the preparation of Rotigotine (1) | 12-26-2013 |
Renata Fuganti, Londrina BR
Patent application number | Description | Published |
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20140075594 | USE OF AT(n) INSERTIONS IN PROMOTER ELEMENTS FOR CONTROLLING THE EXPRESSION LEVELS OF CODING SEQUENCES IN PLANTS - The present invention refers to the use of AT(n) insertions in promoter elements for controlling the expression levels of coding sequences in plants. The expression levels of the heat shock protein (Gmhsp17.6-L), when compared in resistant and susceptible individuals in the population, demonstrated that the largest expression levels per quantitative PCR were present in the individuals that contained the largest AT insertions in the promoter region. The invention also refers to gene expression cassettes containing promoter regions of the gene with different numbers of AT insertions fused to the GUS protein, for transforming soybean embryos. | 03-13-2014 |