Farson
Debbie Farson, San Francisco, CA US
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20110028694 | METHODS TO EXPRESS RECOMBINANT PROTEINS FROM LENTIVIRAL VECTORS - Lentivector constructs for expression of recombinant proteins, polypeptides or fragments thereof and methods of making the same are described. The lentivectors typically have a self-processing cleavage sequence between a first and second protein or polypeptide coding sequence allowing for expression of a functional protein or polypeptide under operative control of a single promoter and may further include an additional proteolytic cleavage sequence which provides a means to remove the self-processing cleavage sequence from the expressed protein or polypeptide. The vector constructs find utility in methods relating to enhanced production of biologically active proteins, such as immunoglobulins or fragments thereof in vitro and in vivo. | 02-03-2011 |
Deborah Farson, Oakland, CA US
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20080241929 | METHOD AND MEANS FOR PRODUCING HIGH TITER, SAFE, RECOMBINANT LENTIVIRUS VECTORS - Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR are useful in the production of recombinant lentivirus vectors (See the Figure). Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production. The vectors can contain inducible or conditional promoters. | 10-02-2008 |
Deborah A. Farson, Oakland, CA US
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20080286836 | METHOD AND MEANS FOR PRODUCING HIGH TITER, SAFE RECOMBINANT LENTIVIRUS VECTORS - Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production. | 11-20-2008 |
Max Robert Farson, Greenville, SC US
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20100329863 | METHOD FOR REDUCING TIP RUB LOADING - A method for reducing tip rub loads in a rotor blade is described having the steps of selecting a location of contact between the rotor blade and a static structure; selecting a location on the blade for incorporating a tip-cutter; selecting a cutter-profile for the tip-cutter; and incorporating the tip-cutter on the selected location on the blade such that tip-cutter is capable of removing a portion of the static structure during a tip rub such that tip rub loads are facilitated to be reduced. | 12-30-2010 |
20100329875 | ROTOR BLADE WITH REDUCED RUB LOADING - An airfoil for use in a rotor assembly is disclosed, the airfoil having a tip-cutter located on a sidewall near a tip portion, wherein the tip-cutter is capable of removing a portion of an abradable material during a tip rub. In another embodiment, an airfoil has a tip-grinder located on the tip portion, wherein the tip-grinder capable of removing a portion of an abradable material during a tip rub. In another embodiment, an airfoil has a tip-rake that facilitates reducing loading induced to said airfoil during tip rubs. | 12-30-2010 |
Max Robert Farson, Greer, SC US
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20120301308 | GAS TURBINE COMPRESSOR LAST STAGE ROTOR BLADES WITH AXIAL RETENTION - A rotor blade and blade retention key assembly includes: a radially outer airfoil, a shank and a radially inner attachment dovetail. The attachment dovetail has a radially innermost surface formed with a notch at one axial end thereof, and a retention key is received in the notch, and rotatable from a retracted position where a retention key portion is substantially flush with the radially innermost surface, to an extended position where the retention key portion projects inwardly from said radially innermost surface and into a recess or pocket formed in a rotor wheel slot to prevent axial movement of the blade within the slot. | 11-29-2012 |
Peter Dean Farson, Glendale, CA US
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20150187113 | MULTIPOINT OFFSET SAMPLING DEFORMATION TECHNIQUES - Systems and methods for performing MOS skin deformations are provided. In one example process, the in vector of a MOS transform may be manually configured by a user. In another example process, a slide/bulge operation may be configured to depend on two or more MOS transforms. Each of the MOS transforms may be assigned a weight that represents the transform's contribution to the overall slide/bulge. In yet another example process, a bulge operation for a MOS vertex may be performed in a direction orthogonal to the attached MOS curve regardless of the direction of the attachment vector. In yet another example process, a ghost transform may be inserted into a MOS closed curve and used to calculate skin deformations associated with first transform of the MOS closed curve. | 07-02-2015 |