Patent application number | Description | Published |
20110212447 | Method of Using FOXO3A Polymorphisms and Haplotypes to Predict and Promote Healthy Aging and Longevity - The invention provides methods and compositions relating to identification and use of genetic information from the FOXO3A gene that can be used for determining and increasing an individual's likelihood of longevity and of retaining physical and cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease, including coronary artery (heart) disease, stroke, cancer, chronic pulmonary disease, diabetes, Parkinson's disease and dementia. | 09-01-2011 |
20130295566 | Method of Using FOXO3A Polymorphisms and Haplotypes to Predict and Promote Healthy Aging and Longevity - The invention provides methods and compositions relating to identification and use of genetic information from the FOXO3A gene that can be used for determining and increasing an individual's likelihood of longevity and of retaining physical and cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease, including coronary artery (heart) disease, stroke, cancer, chronic pulmonary disease, diabetes, Parkinson's disease and dementia. | 11-07-2013 |
Patent application number | Description | Published |
20080285620 | Aspirated Enhanced Total Air Temperature Probe - A total air temperature probe includes an inlet through which airflow enters a primary airflow passage through the probe. A sensor flow passage is connected to the primary flow passage. Bleed ports extend between the primary airflow passage and a cross-port which extends laterally across the probe. An aspiration aperture in the cross-port couples the cross-port to an internal cavity of a strut of the probe. The aspiration aperture can be centered within the cross-port to provide symmetrical deicing heater error behavior of the probe during changes in angle of attack. An aspiration tube couples the internal cavity of the probe to a pressure source. | 11-20-2008 |
20090120195 | Pressure sensor - A pressure transmitter is provided. The pressure transmitter includes a pressure sensor including a pair of process fluid pressure ports each having a deflectable diaphragm. A first variable capacitor is disposed within the pressure sensor and has a capacitance that varies with differential pressure between the process fluid ports. A second variable capacitor is disposed within the pressure sensor and has a capacitance that varies with line pressure. | 05-14-2009 |
20100083768 | Thermal-based diagnostic system for process transmitter - A process transmitter for measuring a process variable in an industrial process comprises a sensor module, a heating device and transmitter circuitry. The sensor module has a sensor for sensing a process variable of an industrial process and generating a sensor signal. The heating device is connected to the sensor module for generating a heat pulse to influence generation of the sensor signal. The transmitter circuitry is connected to the sensor and the heating device. The transmitter circuitry verifies operation of the sensor by measuring a change in the sensor signal due to the heat pulse. In one embodiment of the invention, the heat pulse thermally expands a volume of a fill fluid within the process transmitter. In another embodiment, the heat pulse changes a physical property, such as dielectric, of a fill fluid within the process transmitter. | 04-08-2010 |
20100132472 | METHOD AND APPARATUS FOR PRESSURE MEASUREMENT USING FILL TUBE - A pressure sensor includes a fill tube which is arranged to couple to a process pressure. A sensor is coupled to the fill tube and is configured to measure pressure of fluid in the fill tube as a function of a change of a physical property of the fill tube. Circuitry is provided to measure pressure using the pressure sensor, and to measure pressure based upon the change of the physical property of the fill tube. | 06-03-2010 |
20100132473 | METHOD AND APPARATUS FOR PRESSURE MEASUREMENT USING MAGNETIC PROPERTY - A pressure sensor includes a sensor body which is arranged to couple to a process pressure. The sensor body has a magnetic property which changes as a function of pressure applied by a process fluid. A sensor is coupled to the sensor body and is configured to measure pressure of fluid in the sensor body as a function of a change of magnetic property of the sensor body. | 06-03-2010 |
20110013664 | ASPIRATED ENHANCED TOTAL AIR TEMPERATURE PROBE - A total air temperature probe includes an inlet through which airflow enters a primary airflow passage through the probe. A sensor flow passage is connected to the primary flow passage. Bleed ports extend between the primary airflow passage and a cross-port which extends laterally across the probe. An aspiration aperture in the cross-port couples the cross-port to an internal cavity of a strut of the probe. The aspiration aperture can be centered within the cross-port to provide symmetrical deicing heater error behavior of the probe during changes in angle of attack. An aspiration tube couples the internal cavity of the probe to a pressure source. | 01-20-2011 |
20110239773 | RESONANT FREQUENCY BASED PRESSURE SENSOR - A pressure sensor for sensing a pressure of a process fluid includes a sensor body exposed to the pressure of the process fluid. The sensor body deforms in response to the pressure. A diaphragm suspended from the sensor body has a tension which changes in response to deformation of the sensor body. A resonate frequency of the diaphragm is measured. The measured resonant frequency is indicative of the line pressure of the process fluid and integrity of the isolation fill fluid system. In addition to measuring the resonant frequency, the oscillation mode itself can be used as a diagnostic tool to assess sensor health. | 10-06-2011 |
Patent application number | Description | Published |
20130266538 | Solid Forms of a Thiophosphoramidate Nucleotide Prodrug - The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents. | 10-10-2013 |
20140154210 | Solid Forms of a Thiophosphoramidate Nucleotide Prodrug - The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents. | 06-05-2014 |
20150175647 | SOLID FORMS OF A THIOPHOSPHORAMIDATE NUCLEOTIDE PRODRUG - The present application relates to solid state forms, for example, crystalline forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N-(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents. | 06-25-2015 |
Patent application number | Description | Published |
20120158273 | MULTI-MODE HIGH EFFICIENCY INTERNAL COMBUSTION ENGINE - An internal combustion engine is operable in an efficiency mode providing a first power output range between zero and a transition power output and in a power mode providing a second power output range between the transition power output and a maximum power output. The efficiency mode can include a first ignition timing and a first air/fuel ratio of the mixture to avoid premature auto-ignition, and the power mode can include a second ignition timing and a second air/fuel ratio of the mixture to avoid premature auto-ignition of the mixture. To further enable knock free operation of such an engine, turbulence can be imparted to the mixture to promote a faster burn duration and high temperatures that may lead to premature auto-ignition of the mixture can be avoided. | 06-21-2012 |
20120330534 | ENHANCED EFFICIENCY AND POLLUTANT CONTROL BY MULTI-VARIABLE ENGINE OPERATION CONTROL - Based on one or more monitored operation parameters of an internal combustion engine, a set of engine operation conditions necessary to provide combustion stability in a combustion volume of the engine, optimized fuel efficiency, and minimized production of pollutants such as nitrogen oxides, carbon monoxide, and unburned hydrocarbons can be determined. The new set of engine operation conditions can be dynamically implemented in response to changing engine loads and changing engine speeds to maintain a combustion mixture and combustion conditions within a combustion chamber of the engine constrained flammability limits, pollutant generation rates, and fuel efficiency considerations. Related articles, systems, and methods are described. | 12-27-2012 |
20150040876 | EARLY EXHAUST VALVE OPENING FOR IMPROVED CATALYST LIGHT OFF - Energy to speed heating of a catalyst associated with an internal combustion engine can be provided in the form of sensible energy (heat) via hot combustion products. In some variations, timing of opening and/or closing of an exhaust valve can be manipulated to increase sensible heat delivered to the catalyst in the exhaust gases. | 02-12-2015 |
20150053031 | SCISSOR GEAR WITH HYDRAULIC BACKLASH REMOVAL AND HYDRAULIC TORSIONAL DAMPING - A gear assembly can include a biasing apparatus, which can include a hydraulic biasing member. The biasing apparatus can be activated to urge a scissor gear tooth of a scissor gear toward a second gear tooth of a second gear. The urging of the scissor gear tooth toward the second gear tooth can close a backlash gap between a first gear tooth of a first gear and the second gear tooth of the second gear. | 02-26-2015 |