Patent application number | Description | Published |
20080204009 | Method of Determining a Spatial Distribution of Magnetic Particles - The invention relates to a method of determining a spatial distribution of magnetic particles in an examination zone, in which method a first magnetic field is generated, which forms in the examination zone a first sub-zone having a relatively low magnetic field strength and a second sub-zone having a relatively high magnetic field strength. The position in space of the two sub-zones is then changed by a second magnetic field, whereby the magnetization in the examination zone is changed. Signals dependent on the change in magnetization are acquired and evaluated to extract information concerning the spatial distribution of the magnetic particles. The second magnetic field is generated so that the time derivative of the second magnetic field is substantially identical for each spatial component. | 08-28-2008 |
20090281416 | ARRANGEMENT AND METHOD FOR DETERMINING THE SPATIAL DISTRIBUTION OF MAGNETIC PARTICLES - The invention relates to an arrangement and a method for determining the spatial distribution of magnetic particles in an examination area. Magnetic field means are used to generate a spatially inhomogeneous gradient magnetic field with at least one region with a low field strength, in which the magnetization of the particles is in a state of non- saturation, whereas they are in a state of saturation in the remaining region. By using change means to shift the area with a low field strength within the examination area, a change in the magnetization of the magnetic particles is brought about which can be detected from outside by detection means and contains information about the spatial distribution of the magnetic particles in the examination area. The magnetic field means or the change means or the detection means or a combination of these means are arranged at least partially on a medical instrument. | 11-12-2009 |
20100033171 | ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION - An arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises:—selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action,—drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, wherein the selection means comprises at least one permanent magnet wherein the permanent magnet is at least partially shielded by an electrically high conductive shielding means. | 02-11-2010 |
20100033172 | ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING AND/OR LOCATING MAGNETIC PARTICLES IN A REGION OF ACTION - An arrangement and a method for influencing and/or detecting and/or locating magnetic particles in a region of action is disclosed, which arrangement comprises: —drive means for generating a magnetic drive field so that the magnetization of the magnetic particles changes, wherein the magnetic particles comprise at least a first and a second magnetic particle, —the receiving means comprising at least a first receiving probe providing a first signal ( | 02-11-2010 |
20100033174 | ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION - An arrangement for influencing and/or detecting magnetic particles, a method for calibrating such an arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, the arrangement comprising a drive signal chain, receiving means for acquiring detection signals, which detection signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, the arrangement comprising a detection signal chain, wherein the arrangement comprises a compensation controller providing a compensation signal to the drive signal chain and/or to the detection signal chain by means of a coupling means. | 02-11-2010 |
20100045280 | ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION, COIL ARRANGEMENT - An arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises: selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, receiving means for acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the arrangement comprises a coil arrangement comprising a surrounding coil and a magnetic field generator such that the surrounding coil almost completely surrounds the magnetic field generator. | 02-25-2010 |
20100072984 | INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION OF AN EXAMINATION OBJECT - A method and an arrangement for influencing and/or detecting magnetic particles in a region of action of an examination object is disclosed, which method comprises the steps of: generating a magnetic selection field by means of selection means, the magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field generated by drive means so that the magnetization of the magnetic particles change locally, acquiring signals by means of receiving means, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the selection means and/or the drive means and/or the receiving means are provided at least partly movable relative to the examination object during the acquisition and/or the change in the position in space of the two sub-zones in the region of action. | 03-25-2010 |
20100102805 | METHOD AND ARRANGEMENT FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION - A method and an arrangement for influencing and/or detecting magnetic particles in a region of action is disclosed, which method comprises the steps of: —generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action—changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles change locally, —acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein a magnetic drive vector of the magnetic drive field is rotated in at least one rotation plane. | 04-29-2010 |
20100102806 | ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION - An arrangement for influencing and/or detecting magnetic particles, a method for adjusting such an arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, receiving means for acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the receiving means comprises a first compensation means and a second compensation means the first and second compensation means comprising each a compensation coil. | 04-29-2010 |
20100243574 | SEPARATOR COLUMN, SEPARATOR SYSTEM, METHOD OF FRACTIONATING MAGNETIC PARTICLES, METHOD OF MANUFACTURING A SEPARATOR COLUMN AND USE OF A SEPARATOR COLUMN - A separator system with a separator column and a method of fractionating magnetic particles, preferably using field-flow fractionation is proposed, which allows for more effective fractionation of magnetic particles with respect to their dynamic magnetic response in a wide frequency and amplitude range of an applied magnetic field, in particular relevant for magnetic particle imaging (MPI). | 09-30-2010 |
20100249578 | ARRANGEMENT AND METHOD FOR DETERMINING THE SPATIAL DISTRIBUTION OF MAGNETIC PARTICLES - The invention relates to an arrangement and a method for determining the spatial distribution of magnetic particles in an examination area. Magnetic field means are used to generate a spatially inhomogeneous gradient magnetic field with at least one region with a low field strength, in which the magnetization of the particles is in a state of non-saturation, whereas they are in a state of saturation in the remaining region. By using change means to shift the area with a low field strength within the examination area, a change in the magnetization of the magnetic particles is brought about which can be detected from outside by detection means and contains information about the spatial distribution of the magnetic particles in the examination area. The magnetic field means or the change means or the detection means or a combination of these means are arranged at least partially on a medical instrument. | 09-30-2010 |