Skaar
Anders J. Skaar, Eagan, MN US
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20140061527 | VALVE BODY WITH IMPROVED LOWER FLOW CAVITY - A valve body includes first and second openings, a gallery, and first and second flow conduit portions. The openings are centered on a central axis of the valve body. The gallery is disposed between the openings and includes a cylindrical space on a gallery axis that is perpendicular to the central axis. The first flow conduit portion extends between the first opening and a side opening of the gallery. The second flow conduit portion extends between the second opening and a bottom opening of the gallery. The second flow conduit portion includes a straight cylindrical conduit section in communication with and extending away from the bottom opening of the gallery. The straight cylindrical conduit section has a diameter that is equal to or less than a diameter of the bottom opening of the gallery to facilitate fluid flow through the valve body. | 03-06-2014 |
Eric Skaar, Nashville, TN US
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20100004324 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF - In one aspect, the invention relates to compounds and methods useful for activating heme sensor systems; for decreasing virulence of bacteria, for example, | 01-07-2010 |
Eric P. Skaar, Brentwood, TN US
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20150174130 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS - Embodiments of the presently-disclosed subject matter include activators of HssRS that induce endogenous heme biosynthesis by perturbing central metabolism. These molecules are toxic to fermenting | 06-25-2015 |
Erling A. Skaar, Seattle, WA US
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20100264885 | POWER GENERATOR SYSTEM - A power generating system includes a main engine operated over a range of speeds, an electric generator, and a hydrostatic transmission drivably connecting the engine with the generator to drive the generator at a desired speed. The hydrostatic transmission includes one or more variable pumps. A controller monitors the pump pressure and the generator frequency. The pressure set point is used with the monitored pressure to control the pump output. The pressure set point varies with the generator load, and is adjusted based on the deviation of the generator frequency from a predetermined desired electric power frequency. When multiple pumps are used to drive the motor, the pumps are operated sequentially such that all except one pump is either off or at maximum output. | 10-21-2010 |
Gary Skaar, Marshall, WI US
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20080282909 | Automated Method for Placing Sliced Food Stacks in Packages - A system and method are provided that allow meat logs to be manually loaded into a slicing station and thereafter be continuously automatically processed at the slicing station, a harping station, and an insertion station for automated packaging thereof without the need for handling of the meat stacks by workers. To this end, the slicing station is effective to form smaller sections or chubs from the meat logs and to do so such that the chubs are provided with substantially parallel flat end-faces to ensure that high quality meat slices are generated therefrom. The chubs are then transported to the harping station where each of the chubs undergoes a single cutting operation, thus simultaneously forming the meat slices therefrom and substantially maintaining the slices in the configuration of the chubs for generating well-formed stacks of the slices. Thereafter, the stacks are received at the insertion station where they are transferred to their packages, on an automated basis without the need for manual handling thereof. This is enabled due to the well-formed stacks generated by the harping station which allows the stacks to be dropped into the packages aligned therebelow. | 11-20-2008 |
20110099948 | Automated Method For Placing Sliced Food Stacks In Packages - A system and method are provided that allow meat logs to be manually loaded into a slicing station and thereafter be continuously automatically processed at the slicing station, a harping station, and an insertion station for automated packaging thereof without the need for handling of the meat stacks by workers. To this end, the slicing station is effective to form smaller sections or chubs from the meat logs and to do so such that the chubs are provided with substantially parallel flat end-faces to ensure that high quality meat slices are generated therefrom. The chubs are then transported to the harping station where each of the chubs undergoes a single cutting operation, thus simultaneously forming the meat slices therefrom and substantially maintaining the slices in the configuration of the chubs for generating well-formed stacks of the slices. Thereafter, the stacks are received at the insertion station where they are transferred to their packages, on an automated basis without the need for manual handling thereof. This is enabled due to the well-formed stacks generated by the harping station which allows the stacks to be dropped into the packages aligned therebelow. | 05-05-2011 |
Gary Robert Skaar, Marshall, WI US
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20090263564 | WASHED DEBONED MEAT HAVING HIGH PROTEIN RECOVERY - Deboned meat is subjected to processing in a surimi-type procedure in order to substantially reduce the heme content and thus the color intensity of the deboned meat, with bone marrow components and fat also being removed. When desired, the washed meat is subjected to dewatering, such as by pressing, in order to provide a color and fat reduced deboned meat. Multiple-stage separation is practiced, and the protein yield of the washed meat is advantageously elevated. | 10-22-2009 |
Jeffrey R. Skaar, New York, NY US
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20090275639 | USP47 INHIBTORS AND METHODS TO INDUCE APOPTOSIS - The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates to methods and kits to screen for related agents that induce apoptosis. Additionally, the invention relates to assays for screening compounds capable of acting as USP47 inhibitors. | 11-05-2009 |
20120157507 | USP47 Inhibtors and Methods to Induce Apoptosis - The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates to methods and kits to screen for related agents that induce apoptosis. Additionally, the invention relates to assays for screening compounds capable of acting as USP47 inhibitors. | 06-21-2012 |
20130079385 | USP47 Inhibtors and Methods to Induce Apoptosis - The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates to methods and kits to screen for related agents that induce apoptosis. Additionally, the invention relates to assays for screening compounds capable of acting as USP47 inhibitors. | 03-28-2013 |
Jessica Skaar, San Diego, CA US
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20130028721 | FABRICATION OF LOAD COMPRESSOR SCROLL HOUSING - A method of fabricating a load compressor scroll housing includes the steps of forging near net shape parts that are machined and subsequently welded together. The forged portions are machined to define specific features of the scroll housing along with the mating surfaces. An interface between top and bottom portions is defined within the volute chamber. The weld joint at the interface provides a finished surface within the volute chamber such that airflow is not adversely affected and additional machine process are not required within the volute chamber after formation of the weld joint. | 01-31-2013 |
Kent Skaar, Stow, MA US
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20120030672 | MICROCLOUD PLATFORM DELIVERY SYSTEM - A cloud computing environment with the ability to deploy a web application that has been developed using one of a plurality of application frameworks and is configured to execute within one of a plurality of runtime environments can be delivered as a self-contained virtual machine disk image configured to launch in a virtualization environment. Upon request (or alternatively, in a pre-processing phase), a cloud computing platform provider can compose a virtual machine disk image comprising the cloud computing environment. The virtual machine disk image may be attached to any virtual machine, whether running on a personal computing device such as a laptop or in an infrastructure-as-a-service service provider to provide a cloud computing environment that is automatically configured to receive and deploy a web application. | 02-02-2012 |
20120266156 | RELEASE LIFECYCLE MANAGEMENT SYSTEM FOR A MULTI-NODE APPLICATION - A deployment system provides the ability to deploy a multi-node distributed application, such as a cloud computing platform application that has a plurality of interconnected nodes performing specialized jobs. The deployment system may update a currently running cloud computing platform application according to a deployment manifest and a versioned release bundle that includes jobs and application packages. The deployment system determines changes to the currently running cloud computing platform application and distributes changes to each job to deployment agents executing on VMs. The deployment agents apply the updated jobs to their respective VMs (e.g., launching applications), thereby deploying an updated version of cloud computing platform application. | 10-18-2012 |
20120266158 | RELEASE MANAGEMENT SYSTEM FOR A MULTI-NODE APPLICATION - A deployment system provides the ability to deploy a multi-node distributed application, such as a cloud computing platform application that has a plurality of interconnected nodes performing specialized jobs. The deployment system includes a release management system that builds and manages versioned releases of application services and/or software modules that are executed by the plurality of nodes of the cloud computing platform application. The release management system utilizes specification files to define a jobs and application packages and configurations needed to perform the jobs. The jobs and application packages are assembled into a self-contained release bundle that may be provided to the deployment system. The deployment system unwraps the release bundle and provides each job to deployment agents executing on VMs. The deployment agents apply the jobs to their respective VM (e.g., launching applications), thereby deploying the cloud computing platform application. | 10-18-2012 |
20120266168 | DEPLOYMENT SYSTEM FOR MULTI-NODE APPLICATIONS - A deployment system provides the ability to deploy a multi-node distributed application, such as a cloud computing platform application, which has a plurality of interconnected nodes performing specialized jobs. The deployment system includes a deployment director that provisions an infrastructure that includes one or more virtual machines (VMs) for hosting the plurality of nodes of the cloud computing platform application. The deployment director distributes a plurality of jobs (e.g., application packages and configurations) to deployment agents executing on the provisioned VMs, based on a mapping in the deployment manifest between the infrastructure and the plurality of specialized jobs to be performed by the cloud computing platform application. The deployment agents apply the jobs to their respective VM (e.g., launching applications), thereby deploying the cloud computing platform application. | 10-18-2012 |
Steven B. Skaar, Granger, IN US
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20080300777 | COMPUTER-CONTROLLED POWER WHEELCHAIR NAVIGATION SYSTEM - A wheelchair navigation system for a motorized wheelchair includes dual cameras, proximity sensors, microphones, and rotation sensors for the wheels. Small markers are placed on the walls of a location or room. The navigation system uses the proximity sensors, rotation sensors and cameras in conjunction with the specialized software to determine where objects or impediments are located in the room and thereby redirect the path of the wheelchair so as to avoid such objects. The wheelchair is walked through the marked location thereby ‘teaching’ various paths which are recorded in the computer and recalled later when the wheelchair is in use. The proximity sensor perform sensing operations during performance of the teaching functions for thereby permitting avoidance of wheelchair collision with obstacles during navigation of the wheelchair through a taught trajectory and allowing for close approach of the wheelchair to solid bodies present during performance of the teaching functions. | 12-04-2008 |
Thomas John Skaar, Eagan, MN US
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20140281626 | PHY Based Wake Up From Low Power Mode Operation - Apparatus and method for supplying electrical power to a device. A system on chip (SOC) integrated circuit includes a first region having a processing core and a second region characterized as an always on domain (AOD) power island having a power control block with an energy detector coupled to a host input line. First and second power supply modules respectively supply power to the first and second regions. The second power supply module includes a main switch between the first power supply module and a host input voltage terminal. The power control block opens the main switch to enter a low power mode during which no power is supplied to the first region, and the power control block closes the main switch to resume application of power to the first region responsive to the energy detector detecting electrical energy on the host input line. | 09-18-2014 |
Todd Skaar, Carmel, IN US
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20120088247 | MATERIALS AND METHODS FOR TREATING PATIENTS WITH TAXOXIFEN - A pathway for the metabolism of tamoxifen is identified including the activity of at least 2 different isoforms of UGY2B7. This pathway includes isozymes of CYP3A which convert tamoxifen (TAM) to N-desmethyl-TAM, which is then converted to endoxifen by the action of CYP2D6. Once formed, endoxifen may be degraded by at least one isozyme of UGT2B7. Patients that have highly active isoforms of CYP2D6 and slow acting isoforms of UGT2B7 accumulate high levels of endoxifen and are good candidates for treatment with tamoxifen. Also disclosed are methods for screening patients with a high likelihood of benefiting from treatment with tamoxifen. These methods include testing patients for various alleles of genes known to be involved in tamoxifen metabolism and treating patients accordingly. | 04-12-2012 |