Simons, NL
Aije Jacob Simons, Volendam NL
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20100088986 | METHOD OF CONSTRUCTING A BUILDING, SUCH BUILDING, AND WALL AND FLOOR ELEMENTS FOR USE THEREIN - The invention relates to a method of constructing a building, comprising the step of providing a skeleton for a building wall of the building. The skeleton includes at least upright building elements such as columns or dividing walls. At least one lightweight, heat insulating and fire retarding wall element is placed between each adjacent pair of said columns. The columns are covered to provide substantially closed wall surfaces. The wall surfaces are covered with a covering layer having properties so as to provide fire-resistance to the complete wall. The covering layer on the inside wall surface may include a base layer of modified resin mortar, and a top layer of plaster mortar. The covering layer on the outside wall surface may include a base layer of modified resin mortar and a top layer of mineral mortar. Lightweight, heat insulating floor elements are placed and interconnected, and supported if necessary, and thereafter structural fill-material, such as concrete, is poured onto the floor elements to form a floor. The invention also includes a building, and wall and floor elements. | 04-15-2010 |
Antoine P. Simons, Maastricht NL
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20100042259 | METHOD AND APPARATUS FOR MONITORING AND OPTIMIZING BLOOD CIRCULATION GENERATED BY A PUMP - In a method for the automatic control of blood pumps, an optimization of the blood flow is achieved by periodic speed interventions and flow changes thereby occurring, using a formed differential variable and a control algorithm. In addition, the location of possible flow resistances on the venous or arterial side can be ascertained. | 02-18-2010 |
20140200391 | METHOD AND APPARATUS FOR MONITORING AND OPTIMIZING BLOOD CIRCULATION GENERATED BY A PUMP - In a device for the automatic control of blood pumps, an optimization of the blood flow is achieved by periodic speed interventions and flow changes thereby occurring, using a formed differential variable and a control algorithm. In addition, the location of possible flow resistances on the venous or arterial side can be ascertained. | 07-17-2014 |
Augustinus Franciscus Maria Simons, Maastricht NL
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20100297630 | METHOD FOR THE SIMULTANEOUS DETECTION OF MULTIPLE NUCLEIC ACID SEQUENCES IN A SAMPLE - The invention is in the technical field of detecting nucleic acid sequences in a sample, such as the detection of pathogenic organisms in clinical samples. More specifically, the invention relates to the field of detecting an infection caused by a pathogenic organism such as a virus or a bacterium in a clinical specimen by means of amplifying and detecting specific nucleic acid sequences from said pathogenic organism. It provides a multiplex assay with the possibility to determine about 30 different target nucleic acid sequences in a single one-tube assay combined with real-time probe detection. The method employs multiplex ligation dependent Probe Amplification (MLPA) employing labelled primers in combination with labelled, probes and detection of the fluorescence. | 11-25-2010 |
20150284782 | METHOD FOR THE SIMULTANEOUS DETECTION OF MULTIPLE NUCLEIC ACID SEQUENCES IN A SAMPLE - Detecting nucleic acid sequences in a sample, such as the detection of pathogenic organisms in clinical samples. More specifically, detecting an infection caused by a pathogenic organism such as a virus or a bacterium in a clinical specimen by means of amplifying and detecting specific nucleic acid sequences from said pathogenic organism. A multiplex assay with the possibility to determine about 30 different target nucleic acid sequences in a single one-tube assay combined with real-time probe detection. | 10-08-2015 |
Bert Simons, Amstelveen NL
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20130015137 | METHOD OF MAINTAINING WATER QUALITY IN A PROCESS STREAMAANM Urmenyi; Ana-MarianaAACI UtrechtAACO NLAAGP Urmenyi; Ana-Mariana Utrecht NLAANM Gupta; AmitAACI AuroraAAST ILAACO USAAGP Gupta; Amit Aurora IL USAANM Davies; Chris D.AACI FrodshamAACO GBAAGP Davies; Chris D. Frodsham GBAANM Simons; BertAACI AmstelveenAACO NLAAGP Simons; Bert Amstelveen NL - Disclosed and claimed is a method of removing contaminants from a process stream or stabilizing a system parameter in the process stream. The method includes providing a filtration system in communication with a controller, wherein the controller is operable to automatically initiate a flow from the process stream into the filtration system when the system parameter of the process stream is within above an upper threshold value and/or below a lower threshold value; and activating the filtration system, wherein the flow comprises a flow rate through the filtration system and the controller is operable to adjust the flow rate. | 01-17-2013 |
David Peter Louis Simons, Veldhoven NL
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20080214358 | Audio Interval Training Device - There is provided an audio interval training device, including a sensing unit to obtain a parameter of a user in physical exercise, a memory to store a plurality of audio signals having predetermined tempos; and a processing unit configured to (1) receive a first and second target parameter value, (2) select from the plurality of audio signals a first and second audio signal having respective tempos, (3) alternatively rendering the first and second audio signals, wherein a respective audio signal is rendered to the user corresponding to the first and second target parameter value, as determined by the processing unit using the parameter from the sensing unit. | 09-04-2008 |
20120155387 | SYSTEM AND METHOD FOR SIMPLE PAIRING OF WIRED AND WIRELESS HEALTHCARE DEVICES TO A GATEWAY - A system and method for effecting communication between a plurality of healthcare measurement devices and a remote patient monitoring server is disclosed. In one embodiment, a method of effecting communication between the healthcare measurement devices and the remote patient monitoring server, includes communicating with an healthcare gateway device using a common gateway protocol to receive translated data via a plurality of translation units associated with a plurality of device communication modules residing in wired and wireless healthcare measurement devices, and communicating with the remote patient monitoring server using a plurality of remote protocols residing in a plurality of remote communication modules to transmit the received translated data. In some embodiments, the healthcare gateway device is communicatively coupled between the healthcare management devices and the remote patient monitoring server. | 06-21-2012 |
David P. L. Simons, Veldhoven NL
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20090240521 | REMOTE PATIENT SUPPORT AND CARE BY RELATIVES - A telemonitoring central server | 09-24-2009 |
20090264712 | AUTOMATIC TRANSFER AND IDENTIFICATION OF MONITORED DATA WITH HIERARCHICAL KEY MANAGEMENT INFRASTRUCTURE - A measurement device ( | 10-22-2009 |
Dennis Robert Simons, Eindhoven NL
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20080282743 | Extended-Baking Process for Glass Deposition Tubes - Disclosed is a method of heat treating quartz glass deposition tubes at between 900° C. and 1200° C. for at least 115 hours. The resulting deposition tubes are useful in forming optical preforms that can yield optical fibers having reduced added loss. | 11-20-2008 |
20110226020 | Glass-Tube Extended-Baking Process - Disclosed is a method of heat treating quartz glass deposition tubes at between 900° C. and 1200° C. for at least 115 hours. The resulting deposition tubes are useful in forming optical preforms that can yield optical fibers having reduced added loss. | 09-22-2011 |
20120036896 | Method of Manufacturing an Optical Fibre Preform - The present invention relates to a method for manufacturing a preform for optical fibres, wherein deposition of glass-forming compounds on the substrate takes place. The present invention furthermore relates to a method for manufacturing optical fibres, wherein one end of a solid preform is heated, after which an optical fibre is drawn from said heated end. | 02-16-2012 |
Hubertus Johannes Gertrudus Simons, Venlo NL
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20110010000 | Method for Selecting Sample Positions on a Substrate, Method for Providing a Representation of a Model of Properties of a Substrate, Method of Providing a Representation of the Variation of Properties of a Substrate Across the Substrate and Device Manufacturing Method - A method for selecting sample positions on a substrate from a set of all available sample positions is provided, in which a representation of a model, which may represent the variation of one or more properties across the substrate, is analyzed in order to identify the sample positions having the greatest effect on the model. | 01-13-2011 |
20110128520 | ALIGNMENT SYSTEMS AND METHODS FOR LITHOGRAPHIC SYSTEMS - An alignment system for a lithographic apparatus has a source of alignment radiation; a detection system that has a first detector channel and a second detector channel; and a position determining unit in communication with the detection system. The position determining unit is constructed to process information from said first and second detector channels in a combination to determine a position of an alignment mark on a work piece, the combination taking into account a manufacturing process of the work piece. A lithographic apparatus has the above mentioned alignment system. Methods of alignment and manufacturing devices with a lithographic apparatus use the above alignment system and lithographic apparatus, respectively. | 06-02-2011 |
20110196646 | Alignment System, Lithographic System and Method - A lithographic system includes a lithographic apparatus comprising a projection system which projects a patterned radiation beam onto a target portion of a substrate and an alignment system which measures the position of a feature of the pattern on the substrate at a number of locations over the substrate. A controller compares the measured positions with points on a grid of values and extrapolates values for intermediate positions on the substrate based on values of corresponding intermediate points on the grid, so as to provide an indication of the intermediate positions on the substrate and their displacements relative to the grid. The grid is based on at least one orthogonal basis function, the measurement on the substrate being performed at positions corresponding to the root values of the at least one orthogonal basis function. | 08-11-2011 |
20120218533 | METHOD OF CALCULATING MODEL PARAMETERS OF A SUBSTRATE, A LITHOGRAPHIC APPARATUS AND AN APPARATUS FOR CONTROLLING LITHOGRAPHIC PROCESSING BY A LITHOGRAPHIC APPARATUS - Estimating model parameters of a lithographic apparatus and controlling lithographic processing by a lithographic apparatus includes performing an exposure using a lithographic apparatus projecting a pattern onto a wafer. A set of predetermined wafer measurement locations is measured. Predetermined and measured locations of the marks are used to generate radial basis functions. Model parameters of said substrate are calculated using the generated radial basis functions as a basis function across said substrate. Finally, the estimated model parameters are used to control the lithographic apparatus in order to expose the substrate. | 08-30-2012 |
20130141723 | Alignment Mark Deformation Estimating Method, Substrate Position Predicting Method, Alignment System and Lithographic Apparatus - A method is used to estimate a value representative for a level of alignment mark deformation on a processed substrate using an alignment system. The alignment sensor system is able to emit light at different measuring frequencies to reflect from an alignment mark on the substrate and to detect a diffraction pattern in the reflected light in order to measure an alignment position of the alignment mark. The two or more measuring frequencies are used to measure an alignment position deviation per alignment mark associated with each of the two or more measuring frequencies relative to an expected predetermined alignment position of the alignment mark. A value is determined representative for the spread in the determined alignment position deviations per alignment mark in order to estimate the level of alignment mark deformation. | 06-06-2013 |
20130230797 | Method of Applying a Pattern to a Substrate, Device Manufacturing Method and Lithographic Apparatus for Use in Such Methods - A substrate is loaded onto a substrate support of a lithographic apparatus, after which the apparatus measures locations of substrate alignment marks. These measurements define first correction information allowing the apparatus to apply a pattern at one or more desired locations on the substrate. Additional second correction information is used to enhance accuracy of pattern positioning, in particular to correct higher order distortions of a nominal alignment grid. The second correction information may be based on measurements of locations of alignment marks made when applying a previous pattern to the same substrate. The second correction information may alternatively or in addition be based on measurements made on similar substrates that have been patterned prior to the current substrate. | 09-05-2013 |
20140089870 | Inspection Method and Apparatus and Lithographic Processing Cell - A method of calculating process corrections for a lithographic tool, and associated apparatuses. The method comprises measuring process defect data on a substrate that has been previously exposed using the lithographic tool; fitting a process signature model to the measured process defect data, so as to obtain a model of the process signature for the lithographic tool; and using the process signature model to calculate the process corrections for the lithographic tool. | 03-27-2014 |
20150153656 | Method of Applying a Pattern to a Substrate, Device Manufacturing Method and Lithographic Apparatus for Use in Such Methods - A substrate is loaded onto a substrate support of a lithographic apparatus, after which the apparatus measures locations of substrate alignment marks. These measurements define first correction information allowing the apparatus to apply a pattern at one or more desired locations on the substrate. Additional second correction information is used to enhance accuracy of pattern positioning, in particular to correct higher order distortions of a nominal alignment grid. The second correction information may be based on measurements of locations of alignment marks made when applying a previous pattern to the same substrate. The second correction information may alternatively or in addition be based on measurements made on similar substrates that have been patterned prior to the current substrate. | 06-04-2015 |
Jasper Anne Frido Marikus Simons, Eindhoven NL
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20130284567 | BELT CONVEYOR WITH AN ACTUATOR FOR MOVING THE BELT IN A LATERAL DIRECTION - A positioning assembly is provided with an endless loop conveyor belt for transporting an object and a first and second roller ( | 10-31-2013 |
Johannes M. Simons, Venlo NL
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20090085983 | Inkjet printer - An inkjet printer includes a substantially closed ink duct in which ink is situated. The duct is operationally connected to a piezo-element,. The piezo-element is actuated with a number of actuation signals with appropriate waveforms, generated by a first and second signal generator in order to eject ink drops from the duct nozzle. A pressure wave is generated in the duct by an actuation pulse. The pressure wave causes a deformation of a piezo-element, which generates an electric signal as a result. The waveforms of the first and second signal may be different and do not have to be directly subsequent in time. | 04-02-2009 |
Johannes M.m. Simons, Venlo NL
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20090073206 | METHOD FOR OBTAINING AN IMAGE WITH AN INK JET PRINTER AND A PRINTER SUITABLE FOR PERFORMING THAT METHOD - A method obtains an image from multiple ink droplets transferred to a receiving substrate using an ink jet printer including a plurality of ink chambers operatively filled with ink. Each ink chamber has a nozzle and a corresponding transducer. The ink chambers have mutually distinguishable acoustics. The method includes, for the respective ink chambers, generating an electrical pulse, applying the pulse to the transducer corresponding to a respective ink chamber in order to generate a pressure wave in the ink, such that a droplet of the ink is jetted out of the nozzle at a speed corresponding to the pressure wave, and adjusting the pulse to the acoustics of the respective ink chamber such that the speed at which the droplet is jetted is essentially the same for each ink chamber. A printer is configured for application of the method. | 03-19-2009 |
20090079772 | METHOD FOR OBTAINING AN IMAGE WITH AN INK JET PRINTER AND A PRINTER SUITABLE FOR PERFORMING THAT METHOD - A method obtains an image from multiple ink droplets transferred to a receiving substrate using an ink jet printer including a plurality of ink chambers operatively filled with ink. Each ink chamber has a nozzle and a corresponding transducer. The ink chambers have mutually distinguishable acoustics. The method includes, for the respective ink chambers, generating an electrical pulse, applying the pulse to the transducer corresponding to a respective ink chamber in order to generate a pressure wave in the ink, such that a droplet of the ink is jetted out of the nozzle having a size corresponding to the pressure wave, and adjusting the pulse to the acoustics of the respective ink chamber such that the size of the droplet which is jetted is essentially the same for each ink chamber. A printer is configured for application of the method. | 03-26-2009 |
20110261097 | DRIVER CIRCUIT FOR DRIVING A PRINT HEAD OF AN INKJET PRINTER - An inkjet printing apparatus includes a print head having an ink duct, a piezoelectric element operatively coupled to the ink duct, and a control device for controlling an ink drop ejection from the ink duct by actuation of the piezoelectric element. The control device includes a current source, a number of power supplies, and a switch, connected between the current source and the number of power supplies. The current source is configured to generate a current for actuating the piezoelectric element by charging and discharging. The switch is configured to connect the current source and one of the number of power supplies. The one of the number of power supplies is selected such that a lowest voltage difference over the current source exists. | 10-27-2011 |
Marcel P. Simons, Aalten NL
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20080246730 | Computer Input Device with Improved Control Performance - The invention relates to a computer input device comprising means for registering a displacement of said device relative to a substrate for selection of an item on a display panel. The computer input device comprises a device bottom, intended to face said substrate in use of said computer input device. The selection device comprises one or more protruding legs extending from said device bottom. At least one of said protruding legs is shaped to press, during use of said computer input device, a substantially streamlined hole in said substrate. | 10-09-2008 |
Paul R. Simons, Eindhoven NL
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20100035546 | LOCATING REFERENCE NODES FOR POSITIONING DEVICES IN A WIRELESS NETWORK - A method for matching an actual device in a wireless network to a corresponding device indicated in a plan ( | 02-11-2010 |
Peter J. Simons, Hillegom NL
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20090311268 | CD40-BINDING ACTIVATING ANTIBODIES - Disclosed are agonist anti-CD40 molecules, including monoclonal antibodies, which can bind to and stimulate professional and non-professional human antigen-presenting cells (“APCs”), enhance the stimulatory effect of CD40L on CD40 positive cells and/or induce phenotypical maturation of monocyte derived dendritic cells. Several such monoclonal antibodies are provided, and cell lines producing them have been deposited at the American Type Culture Collection. | 12-17-2009 |
Petrus Johannes Simons, Utrecht NL
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20140377284 | HUMANIZED ANTI-CD134 (OX40) ANTIBODIES AND USES THEREOF - The invention provides antibodies that specifically bind to human CD134. Anti-human CD134 antibodies specifically bind to the extracellular domain of human CD134, including non-OX40 ligand (OX40L) binding domains on human CD134, which is expressed on e.g. activated human conventional effector CD4 and/or CD8 T lymphocytes (Teffs) and on activated human suppressive regulatory CD4 T lymphocytes (Tregs). Humanized anti-human CD134 antibodies are useful (e.g. to empower Teffs anti-cancer effector function and/or to inhibit Tregs suppressive function) for cancer treatment. | 12-25-2014 |
Petrus Johannes Simons, Hillegom NL
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20150132288 | ANTI-CD134 (OX40) ANTIBODIES AND USES THEREOF - The invention provides antibodies that specifically bind to human CD134. Invention anti-human CD134 antibodies specifically bind to the extracellular domain of human CD134, including non-OX40 ligand (OX40L) binding domains on human CD134, which is expressed on e.g. activated human conventional effector CD4 and/or CD8 T lymphocytes (Teffs) and on activated human suppressive regulatory CD4 T lymphocytes (Tregs). Invention anti-human CD134 antibodies are useful (e.g. to empower Teffs anti-cancer effector function and/or to inhibit Tregs suppressive function) for cancer treatment. | 05-14-2015 |
Petrus Wijnandus Simons, Schaijk NL
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20130194886 | PHYSICAL UNCLONABLE FUNCTION WITH IMPROVED START-UP BEHAVIOR - An electric physical unclonable function (PUF) ( | 08-01-2013 |
20130234771 | PHYSICAL UNCLONABLE FUNCTION - A physical unclonable function is provided | 09-12-2013 |
Ruud Simons, Ep Alphen Aan Den Rijn NL
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20150290271 | Nutraceutical Composition Obtained from Fungus-Challenged Soy Seedlings - Soybean seedlings and therefrom extractable compositions are described. Such compositions comprise prenylated isoflavones and at least one isoflavonoid, said isoflavonoid being selected from one of the chemical classes of isoflavones, coumestans and pterocarpans. Such compositions usually comprise at least 5% prenylated isoflavones, in particular prenylated isoflavones selected from prenylated daidzein, prenylated hydroxydaidzein, prenylated glycitein, prenylated hydroxygenistein, and prenylated genistein. Such compositions also comprise pterocarpans, preferably in amounts of at least 20%, and with a novel ratio of glyceollin I to glyceollin II to glyceollin III to glyceollin IV. Also described is a production method comprising the step of fermenting the soybeans under stress, in particular in the presence of cultures of fungi, preferably in the presence of | 10-15-2015 |