Patent application number | Description | Published |
20080292729 | Stabilized Chlorite Solutions in Combination with Fluoropyrimidines for Cancer Treatment - Pharmaceutical compositions for treating neoplastic disorders and uses thereof are provided. Said pharmaceutical compositions comprise stabilized chlorite solutions (e.g. WFIO) and a fluoropyrimidine, 5-FU, or a 5-FU prodrug (e.g. capecitabine, doxifluridine, UFT, S-1, or BOF-A2). The use of the above stabilized chlorite solution in combination with a fluoropyrimidine dramatically improves the quality of life index (QOL) of a patient undergoing cancer chemotherapy. Cancers that can be treated include cancers of the pancreas, gastrointestinal, head, neck, and breast. | 11-27-2008 |
20130202719 | STABILIZED CHLORITE SOLUTIONS IN COMBINATION WITH FLUROPYRIMIDINES FOR CANCER - Pharmaceutical compositions for treating neoplastic disorders and uses thereof are provided. Said pharmaceutical compositions comprise stabilized chlorite solutions (e.g. WFIO) and a fluoropyrimidine, 5-FU, or a 5-FU prodrug (e.g. capecitabine, doxifluridine, UFT, S-1, or BOF-A2). The use of the above stabilized chlorite solution in combination with a fluoropyrimidine dramatically improves the quality of life index (QOL) of a patient undergoing cancer chemotherapy. Cancers that can be treated include cancers of the pancreas, gastrointestinal, head, neck, and breast. | 08-08-2013 |
Patent application number | Description | Published |
20100233118 | USE OF WF10 FOR TREATING ALLERGIC ASTHMA, ALLERGIC RHINITIS AND ATOPIC DERMATITIS - The present invention provides a method of inhibiting at least one of allergic asthma, allergic rhinitis and atopic. The present invention further provides a method for the reduction, prevention or treatment of allergy like symptoms in a subject. | 09-16-2010 |
20120294849 | USE OF WF10 FOR TREATING ALLERGIC ASTHMA, ALLERGIC RHINITIS AND ATOPIC DERMATITIS - The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions. | 11-22-2012 |
20130295200 | USE OF WF10 FOR TREATING ALLERGIC ASTHMA, ALLERGIC RHINITIS AND ATOPIC DERMATITIS - The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions. | 11-07-2013 |
Patent application number | Description | Published |
20080291938 | Connecting Device for Randomly Connecting a Number of Transmitters and Receivers, Communication Device and Method for Producing Connecting Device - A connection device for random connection of a first member of first transmission/reception units with a second number of second transmission/reception units has a switching matrix that includes a third number of controllable micromechanical switching elements that are respectively activatable to establish a connection between one of the first transmission/reception units and one of the second transmission/reception units. A control circuit selectively activates the respective micromechanical switching elements to selectively establish respective connections between the first number of first transmission/reception units and the second number of transmission/reception units. | 11-27-2008 |
20090284101 | Device for Converting Mechanical Energy Into Electrical Energy, and Method for Operating Said Device - A device for converting mechanical energy into electrical energy has first electrode formed of a first material having a first work function for a charge carrier, and a second electrode formed of a second material having a second work function for a charge carrier, the second work function being different from the first work function. The first electrode and the second electrode are interconnected by a first load circuit in an electroconductive manner. The second electrode is arranged at a variable distance from the first electrode. | 11-19-2009 |
20100176694 | PIEZOELECTRIC ENERGY CONVERTER HAVING A DOUBLE MEMBRANE - A first dynamically deflectable membrane structure has two electrode layers and one piezoelectric layer for converting mechanical capacity into electrical capacity, and vice versa. The first membrane structure is mechanically coupled to extra weight. Mechanical and electrical capacities are provided which reduce a non-linear portion of a resetting force of the membrane structure. A second membrane structure is mechanically counter-coupled to the first membrane structure such that both membrane structures are mechanically biased in opposite directions by the extra weight. In this manner, a linearization of the resetting forces occurs as a function of the membrane deflection. The piezoelectric energy converter can generate an electrical capacity of, for example, 0.4 watts to 10 watts. | 07-15-2010 |
20100259130 | Device for energy conversion, in particular a piezoelectric micropower converter - An apparatus, in particular a microsystem, includes a device for energy conversion. The device for energy conversion has a piezoelectric, mechanically vibrating diaphragm structure for converting mechanical energy into electrical energy and/or vice versa, the diaphragm structure being arranged encapsulated in an environment which has a predetermined pressure which is, in particular, lower than an isostatic pressure. | 10-14-2010 |
20100295413 | DEVICE COMPRISING A CAPACITIVE ENERGY CONVERTER THAT IS INTEGRATED ON A SUBSTRATE - The embodiments relate to a device, especially a microsystem, which comprises an energy converter unit having an electrode structure for the capacitive conversion of mechanical energy to electrical energy The electrode structure includes a first electrode and a second electrode the distance of which to the first electrode is variable. The device according to the invention also comprises a load circuit via which the first and second electrode are interconnected in an electroconductive manner. A transmitter is coupled to the second electrodes. The distance between the first and the second electrode can be varied by displacing the transmitter and the displacement of the transmitter can be effected in a countactles manner by interaction of the transmitter with a mobile part. | 11-25-2010 |
20100301707 | APPARATUS FOR ENERGY CONVERSION, IN PARTICULAR A PIEZOELECTRIC MICROPOWER CONVERTER - The embodiments describe an apparatus, in particular a microsystem, including a device for energy conversion, which device has apiezoelectric, mechanically vibrating diaphragm structure for converting mechanical energy into electrical energy. The diaphragm structure being coupled to a transformer and it being possible to displace said diaphragm structure by moving the transformer, and it being possible to effect the movement of the transformer in a contact-free fashion by interaction of the transformer with a moving part. | 12-02-2010 |
20120119621 | BENDING DEVICE FOR BENDING A PIEZOELECTRIC BENDER, PIEZOELECTRIC CONVERTER FOR CONVERTING MECHANICAL ENERGY INTO ELECTRICAL ENERGY, BY USING THE BENDING DEVICE, AND METHOD FOR CONVERTING MECHANICAL ENERGY INTO ELECTRICAL ENERGY - A workpiece having a bearing surface with at least one convex curvature and an opposing workpiece having an opposing bearing surface with a concave curvature essentially inverse to the convex curvature of the bearing surface are moved by a device relative to each other in such a manner that the convex curvature of the bearing surface can be guided into the concave curvature of the opposing bearing surface. To convert energy, a bending element, such as a disk bender, is located in a space between the bearing surface and the opposing bearing surface so that the movement of the workpiece and the opposing workpiece relative to each other results in the bending of the bending element. Mechanical energy can be converted into electrical energy with higher efficiency by using a disk bender. The workpieces and the bearing surfaces thereof are formed to provide overload protection. | 05-17-2012 |
Patent application number | Description | Published |
20100176694 | PIEZOELECTRIC ENERGY CONVERTER HAVING A DOUBLE MEMBRANE - A first dynamically deflectable membrane structure has two electrode layers and one piezoelectric layer for converting mechanical capacity into electrical capacity, and vice versa. The first membrane structure is mechanically coupled to extra weight. Mechanical and electrical capacities are provided which reduce a non-linear portion of a resetting force of the membrane structure. A second membrane structure is mechanically counter-coupled to the first membrane structure such that both membrane structures are mechanically biased in opposite directions by the extra weight. In this manner, a linearization of the resetting forces occurs as a function of the membrane deflection. The piezoelectric energy converter can generate an electrical capacity of, for example, 0.4 watts to 10 watts. | 07-15-2010 |
20100259130 | Device for energy conversion, in particular a piezoelectric micropower converter - An apparatus, in particular a microsystem, includes a device for energy conversion. The device for energy conversion has a piezoelectric, mechanically vibrating diaphragm structure for converting mechanical energy into electrical energy and/or vice versa, the diaphragm structure being arranged encapsulated in an environment which has a predetermined pressure which is, in particular, lower than an isostatic pressure. | 10-14-2010 |
20100301707 | APPARATUS FOR ENERGY CONVERSION, IN PARTICULAR A PIEZOELECTRIC MICROPOWER CONVERTER - The embodiments describe an apparatus, in particular a microsystem, including a device for energy conversion, which device has apiezoelectric, mechanically vibrating diaphragm structure for converting mechanical energy into electrical energy. The diaphragm structure being coupled to a transformer and it being possible to displace said diaphragm structure by moving the transformer, and it being possible to effect the movement of the transformer in a contact-free fashion by interaction of the transformer with a moving part. | 12-02-2010 |
20120240672 | MINIATURIZED ENERGY GENERATION SYSTEM - An autonomous energy generation system, in particular designed as an integrated miniaturized energy generation system based on MEMS technology, has a piezoelectric energy converter for converting mechanical energy into electrical energy, and has at least one piezoelectric element into which mechanical force (in particular deformation force) induced by a fluid flow can be coupled. The piezoelectric element is excited to vibrate mechanically. An integrated circuit (ASIC) is used for managing the energy provided by the piezoelectric energy converter. | 09-27-2012 |
Patent application number | Description | Published |
20130274424 | PROCESS FOR MONITORING THE POLYMERIZATION OF ETHYLENE OR ETHYLENE AND COMONOMERS IN A TUBULAR-REACTOR AT HIGH-PRESSURES - Process for monitoring the polymerization of ethylene or ethylene and comonomers in the presence of free-radical polymerization initiator at pressures in the range of from 160 MPa to 350 MPa and temperatures in the range of from 100° C. to 350° C. in a tubular reactor with one or more reaction zones, which is equipped with cooling jackets for cooling the tubular reactor with a cooling medium, comprising the steps of a) measuring as process parameters the temperature profile and the pressure of the reaction medium and the flow and temperature profile of the cooling medium along the reactor, b) monitoring the feeds of ethylene, if present comonomer, free-radical polymerization initiator and chain-transfer agent to all reaction zones, c) calculating, based on the measured process parameters and on a model for the polymerization process, concentrations for free-radical polymerization initiator, chain-transfer agent, ethylene and, if present, comonomers at at least so many positions along the reactor, that at least one calculation is carried out all 10 s for a volume unit flowing through the reactor, d) calculating, based on the measured process parameters and the calculated concentrations, the cooling power, the generation of heat, and the concentration of radicals, e) calculating, based on the calculated data of the cooling power, of the generation of heat, and of the concentration of radicals, the potential of a thermal runaway of the reaction mixture at the positions along the reactor which have the highest temperatures, and f) outputting an alarm signal if the calculated value for the potential of a thermal runaway exceeds a predefined value and process for polymerizing ethylene or ethylene and comonomers comprising such a monitoring process. | 10-17-2013 |
Patent application number | Description | Published |
20100074946 | PROCESS FOR PREPARING PURIFIED NUCLEIC ACID AND THE USE THEREOF - The invention relates to a nucleic acid preparation with a content of below 1% protein, preferably below 0.1% protein, free of ethidium bromide, phenol, cesium chloride and detergents based on octyl phenol poly(ethylene glycol ether) | 03-25-2010 |
20100196961 | VARIABLE TANGENTIAL FLOW FILTRATION - The current invention reports a method for concentrating an immunoglobulin solution by tangential flow filtration wherein the transmembrane pressure and the cross-flow are variable. | 08-05-2010 |
20100249384 | IMMUNOGLOBULIN AGGREGATES - The current invention reports a method for concentrating an immunoglobulin solution by tangential flow filtration wherein the immunoglobulin in polymeric form can be removed after the concentration. | 09-30-2010 |
20110293708 | PROCESS FOR PREPARING PURIFIED NUCLEIC ACID AND THE USE THEREOF - The invention relates to a nucleic acid preparation with a content of below 1% protein, preferably below 0.1% protein, free of ethidium bromide, phenol, cesium chloride and detergents based on octyl phenol poly(ethylene glycol ether) | 12-01-2011 |
20120177640 | OPTIMIZING THE PRODUCTION OF ANTIBODIES - A general method is provided for the production of purified antibodies by separation of an antibody molecule from an antibody variant by chromatographic methods, e.g. to enhance therapeutic efficacy, by for example choosing a specific harvesting time point and/or a specific purification scheme. The current invention thus reports a method for producing an antibody composition comprising an antibody molecule and a variant thereof, comprising the following steps: providing a sample comprising the antibody molecule and a variant thereof, determining the presence of the antibody molecule and/or a variant thereof and/or the ratio of the amount of the antibody molecule or variant thereof to the sum of the amounts of the antibody molecule and the variant thereof, in an aliquot of said sample, determining a subsequent harvesting time point and/or antibody purification scheme on basis of the data obtained before, thereby producing an antibody composition comprising the antibody molecule and a variant thereof. | 07-12-2012 |
20120197007 | METHOD FOR PURIFYING PEGylated ERYTHROPOIETIN - Herein is reported a method for the purification of a protein comprising erythropoietin and a single poly(ethylene glycol) residue from reaction by-products or not reacted starting material by a cation exchange chromatography method. It has been found that by employing a cation exchange SP Sephacryl™ S 500 HR chromatography material conditioned to a conductivity of 21 mS/cm and a linear gradient elution a fusion protein of erythropoietin and a single poly(ethylene glycol) residue can be obtained in a single step with high purity and yield. | 08-02-2012 |
20120219990 | PRE-FILTRATION ADJUSTMENT OF BUFFER SOLUTES - Herein is reported a tangential flow filtration method with a pre-filtration solute concentration adjustment in order to ensure a defined concentration of the components of the solution after tangential flow filtration. | 08-30-2012 |
20130004562 | PROCESS FOR PREPARING PURIFIED NUCLEIC ACID AND THE USE THEREOF - The invention relates to a nucleic acid preparation with a content of below 1% protein, preferably below 0.1% protein, free of ethidium bromide, phenol, cesium chloride and detergents based on octyl phenol poly(ethylene glycol ether) | 01-03-2013 |
20130109056 | Immunoglobulin aggregate removal | 05-02-2013 |
20130315985 | PROCESS FOR PREPARING PURIFIED NUCLEIC ACID AND THE USE THEREOF - The invention relates to a nucleic acid preparation with a content of below 1% protein, preferably below 0.1% protein, free of ethidium bromide, phenol, cesium chloride and detergents based on octyl phenol poly(ethylene glycol ether) | 11-28-2013 |
20140163207 | METHOD FOR PURIFYING PEGylated ERYTHROPOIETIN - Herein is reported a method for the purification of a protein comprising erythropoietin and a single poly (ethylene glycol) residue from reaction by-products or not reacted starting material by a cation exchange chromatography method. It has been found that by employing a cation exchange SP Sephacryl™ S 500 HR chromatography material conditioned to a conductivity of 21 mS/cm and a linear gradient elution a fusion protein of erythropoietin and a single poly (ethylene glycol) residue can be obtained in a single step with high purity and yield. | 06-12-2014 |
20140287026 | PROCESS FOR PREPARING PURIFIED NUCLEIC ACID AND THE USE THEREOF - The invention relates to a nucleic acid preparation with a content of below 1% protein, preferably below 0.1% protein, free of ethidium bromide, phenol, cesium chloride and detergents based on octyl phenol polyethylene glycol ether) | 09-25-2014 |