Patent application number | Description | Published |
20080199249 | METHOD FOR ANCHORING A JOINING ELEMENT IN AN OBJECT AND JOINING ELEMENT TO BE USED IN THE METHOD - A joining element to be anchored in an object ( | 08-21-2008 |
20100313517 | METHOD FOR ANCHORING A JOINING ELEMENT IN AN OBJECT AND JOINING ELEMENT TO BE USED IN THE METHOD - A joining element to be anchored in an object with the aid of a thermoplastic material and mechanical vibration comprises a sealing portion and a wall anchoring portion. The sealing portion is substantially cylindrical and has a smooth circumferential surface. The wall anchoring portion has a circumferential surface which comprises the thermoplastic material and energy directors. A cross section of the sealing portion envelops the cross section (including energy directors) of the wall anchoring portion and is arranged adjoining to the latter on its proximal side. The joining element is anchored in an opening provided in the object wherein a cross section of the opening corresponds to the cross section of the sealing portion of the joining element such that the latter can be forced into a mouth of the opening resulting in a press fit. For anchoring the joining element in the opening, mechanical vibrations e.g. ultrasonic vibrations are coupled into the joining element and the latter is forced into the opening until at least a distal part of the sealing portion is positioned within the opening. Thereby, the thermoplastic material of the circumferential surface of the wall anchoring portion is liquefied and pressed into the opening wall, wherein the sealing portion prevents the liquefied material to penetrate through the mouth and therefore the mouth remains clear cut, i.e. does not get blurred by the liquefied material. | 12-16-2010 |
20110206448 | METHOD FOR JOINING TWO OBJECTS AND CORRESPONDING JOINING ELEMENT - A first and a second object ( | 08-25-2011 |
20120291262 | METHOD FOR JOINING TWO OBJECTS AND CORRESPONDING JOINING ELEMENT - A first and a second object are joined with the aid of a joining element including at least in the region of its distal and proximal ends a thermoplastic material. Two blind holes facing each other are provided in the two objects and the joining element is positioned in the blind holes such that its distal and proximal ends are in contact with the bottom faces of the blind holes and such that there is a gap between the two objects. This assembly is then positioned between a support and a sonotrode. The sonotrode and the support are forced towards each other, while the sonotrode is vibrated, thereby liquefying at least part of the material having thermoplastic properties, there, where the joining element ends are pressed against the bottom faces of the holes and allowing the liquefied material to infiltrate into pores. | 11-22-2012 |
20140237939 | METHOD FOR ANCHORING A JOINING ELEMENT IN AN OBJECT AND JOINING ELEMENT TO BE USED IN THE METHOD - A method of anchoring a joining element to a hollow core board with the aid of mechanical vibration. The hollow core board has a first and second outer layers and a middle layer disposed between the outer layers. An opening, including a mouth, is provided in the hollow core board, the opening penetrating the first outer layer and the middle layer. The joining element includes a wall anchoring portion situated between a proximal end and a distal end thereof. A distal end of the wall anchoring portion is positioned into or onto the mouth with a sealing portion on a proximal end of the wall anchoring portion. The wall anchoring portion is forced through the mouth by applying mechanical vibration and a force parallel to the joining element axis, whereby thermoplastic material of the wall anchoring portion is liquefied and pressed into the first outer layer. | 08-28-2014 |
20150110547 | MANUFACTURING MICRO-STRUCTURED ELEMENTS - An assembly including a joining element and an object, the object having a first outer layer, a second outer layer, and a middle layer between the first and second outer layers. The object has an opening that extends through the first outer layer and the middle layer, and the joining element is anchored in the opening. The joining element includes a proximal end, a distal end, a contact face in the area of the proximal end, a wall anchoring portion, and a tubular portion. The contact face is engaged by a vibrating tool that applies mechanical vibration and axial force to the joining element. The joining element includes a thermoplastic material at least at the circumferential surface of the wall anchoring portion and at the distal end to anchor the joining element to the first and second outer layers, respectively. | 04-23-2015 |
Patent application number | Description | Published |
20090325986 | Deazapurine Analogs of 1'-Aza-L-Nucleosides - The invention relates to compounds of the formula (I), which are L-enantiomeric forms of nucleoside analogues, and to pharmaceutical compositions containing the compounds, methods of treating certain diseases, including cancer, bacterial infection, parasitic infection, and T-cell mediated diseases, using the compounds, processes for preparing the compounds, and intermediates useful in the preparation of the compounds. | 12-31-2009 |
20110046167 | ACYCLIC AMINE INHIBITORS OF 5-METHYTIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE - The present invention relates to compounds of the general formula (I) which are inhibitors of 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds. | 02-24-2011 |
20110130412 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases - The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds. | 06-02-2011 |
20130274220 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE - The present invention discloses methods for treating bacterial infections in a subject comprising administering to the subject a sub-growth inhibiting amount of a 5′-methylthioinosine phosphorylase (MTIP) inhibitor, as well as assays for identifying such inhibitors, and compounds and pharmaceutical compositions comprising the inhibitors. | 10-17-2013 |
20140303367 | Methods for Synthesizing Molybdopterin Precursor Z Derivatives - Provided herein are synthetic methods for preparing a compound of formula (I): | 10-09-2014 |
20140323726 | Methods for synthesizing molybdopterin precursor Z derivatives - Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency. | 10-30-2014 |
20150210701 | TREATMENT OF HELICOBACTER PYLORI INFECTIONS - Methods of treating infections due to | 07-30-2015 |
Patent application number | Description | Published |
20080285795 | METHOD AND APPARATUS FOR ACQUIRING DIGITAL MICROSCOPE IMAGES - A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images. | 11-20-2008 |
20120293645 | METHOD AND APPARATUS FOR ACQUIRING DIGITAL MICROSCOPE IMAGES - A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images. | 11-22-2012 |