Patent application number | Description | Published |
20090142504 | Method and Apparatus for Single Side Bilayer Formation - An apparatus for single-sided bilayer formation includes a first fluid chamber including a sidewall and a second fluid chamber extending through the sidewall. A barrier wall separates the first and second fluid chambers and includes a nanopore therein across which a planar lipid bilayer (PLB) is formed. In use, an electrolyte is added to the first and second fluid chambers and a lipid/organic solvent mixture is added to the first fluid chamber to form a lipid/organic solvent layer. The electrolyte level within the first fluid chamber is adjusted such that the lipid layer is raised above the barrier wall and a PLB is formed. Electrolyte levels may be adjusted manually or utilizing a fluid level regulator with or without feedback control. Optionally, the apparatus may be in the form of a nanopore array. The apparatus may be incorporated into an ion channel sensing system wherein an electrical current through each PLB is separately recorded. | 06-04-2009 |
20090222216 | System and Method to Improve Accuracy of a Polymer - The sequencing of individual monomers (e.g., a single nucleotide) of a polymer (e.g., DNA, RNA) is improved by reducing the motion of the polymer due to thermally-driven diffusion to reduce the spatial error in the position of the polymer within a measurement device. A major system parameter, such as average translocation velocity or measurement time, is selected based on the characteristics of the sensing system utilized, and an algorithm jointly optimizes the sequencing order error rate and the monomer identification error rate of the system. | 09-03-2009 |
20110162963 | System and Method for Increasing Polymer/Nanopore Interactions - An electrolytic system includes an analyte chamber having an access port for introducing a sample containing a molecules of interest, such as DNA. Electrodes create an electric field along a length of the analyte chamber to drive molecules toward an interaction region containing a nanopore, thereby increasing the arrival rate of molecules at the nanopore. Additional electrodes may be utilized to create an electric field through the nanopore to drive a molecule into the nanopore. A current sensor may be utilized to count, discriminate or characterize the molecules as they interact with the nanopore. Advantageously, system can be utilized for unamplified DNA sequencing. | 07-07-2011 |
20120139564 | Method and Apparatus for Single Side Bilayer Formation - An apparatus for single-sided bilayer formation includes a first fluid chamber including a sidewall and a second fluid chamber extending through the sidewall. A barrier wall separates the first and second fluid chambers and includes a nanopore therein across which a planar lipid bilayer (PLB) is formed. In use, an electrolyte is added to the first and second fluid chambers and a lipid/organic solvent mixture is added to the first fluid chamber to form a lipid/organic solvent layer. The electrolyte level within the first fluid chamber is adjusted such that the lipid layer is raised above the barrier wall and a PLB is formed. Electrolyte levels may be adjusted manually or utilizing a fluid level regulator with or without feedback control. Optionally, the apparatus may be in the form of a nanopore array. The apparatus may be incorporated into an ion channel sensing system. | 06-07-2012 |
20120298516 | METHOD AND APPARATUS FOR SINGLE SIDE BILAYER FORMATION - An apparatus for single-sided bilayer formation includes a first fluid chamber including a sidewall and a second fluid chamber extending through the sidewall. A barrier wall, having at least a portion defining a hydrophobicity or hydrophilicity surface property, separates the first and second fluid chambers and includes a nanopore therein across which a planar lipid bilayer (PLB) is formed. In use, an electrolyte is added to the first and second fluid chambers and a lipid/organic solvent mixture is added to the first fluid chamber to form a lipid/organic solvent layer. The electrolyte level within the first fluid chamber is adjusted such that the lipid layer is raised above the barrier wall and a PLB is formed through single-sided spontaneous formation from the first fluid chamber across the nanopore. | 11-29-2012 |
20120310543 | System and Method to Improve Sequencing Accuracy of a Polymer - The sequencing of individual monomers (e.g., a single nucleotide) of a polymer (e.g., DNA, RNA) is improved by reducing the motion of the polymer due to thermally-driven diffusion to reduce the spatial error in the position of the polymer within a measurement device. A major system parameter, such as average translocation velocity or measurement time, is selected based on the characteristics of the sensing system utilized, and an algorithm jointly optimizes the sequencing order error rate and the monomer identification error rate of the system. | 12-06-2012 |
Patent application number | Description | Published |
20090016009 | Carrierless Storage System Enclosure with Ejection Mechanism - A carrierless storage system enclosure includes an ejection mechanism to permit installation and removal of data storage devices (e.g., hard disk drives) without tools, carriers, and manual cabling. | 01-15-2009 |
20090292850 | File System Adapter for Hardware Implementation or Acceleration of File System Functions - A file system adapter card that may be plugged into a host computer system for providing hardware-based file system accesses outside the purview of a host operating system running on the host computer system. The file system adapter card includes a hardware-implemented or hardware-accelerated file service subsystem and a computer bus that permits a host computer system to communicate directly with the file service subsystem for providing file service requests and receiving file service responses. The file service subsystem includes dedicated hardware that operates outside the immediate control of a host operating system, including specialized circuitry for performing at least one major subsystem function. | 11-26-2009 |
20110035565 | Storage System Condition Indicator and Method - A storage system condition indicator and method provides a visual display representing the operating condition of a set of storage devices. Various operating conditions may be defined based on available storage capacity and capacity to store data redundantly. One or more indicators may be used to represent the operating condition of the set of storage devices. The indicator(s) may be used to indicate whether additional storage capacity is recommended and, in a storage array, which slot in the array should be updated with additional storage capacity. | 02-10-2011 |
20110113194 | Filesystem-Aware Block Storage System, Apparatus, and Method - A filesystem-aware storage system locates and analyzes host filesystem data structures in order to determine storage usage of the host filesystem. To this end, the storage system might locate an operating system partition, parse the operating system partion to locate its data structures, and parse the operating system data structures to locate the host filesystem data structures. The storage system manages data storage based on the storage usage of the host file system. The storage system can use the storage usage information to identify storage areas that are no longer being used by the host filesystem and reclaim those areas for additional data storage capacity. Also, the storage system can identify the types of data stored by the host filesystem and manage data storage based on the data types, such as selecting a storage layout and/or an encoding scheme for the data based on the data type. | 05-12-2011 |
20110154123 | System and Method for Protecting Users of Data Storage Systems Against Know Problems - Methods and apparatus automatically identify certain types of data storage system problems, such as a flawed storage device or an incompatibility between a data storage system and a data storage device or an incompatibility between the storage system and a user computer. The existence of such a problem may be highlighted to a user through an indicator on the storage system and/or through a “dashboard” application being executed by the user computer, and the problem may be automatically corrected by automatically downloading a fix (e.g., new firmware or a “patch”) from a server (e.g., a server managed by the storage device manufacturer, a server managed by the storage system manufacturer and/or a server managed by a third party) and automatically implementing the fix. | 06-23-2011 |
20120271799 | Apparatus and Method for Hardware-Based File System - A hardware-based file system includes multiple linked sub-modules that perform functions ancillary to client data handling. Each sub-module is associated with a metadata cache. A doubly-rooted structure is used to store each file system object at successive checkpoints. Metadata is stored within an object and/or as a separate object. Provisions are made for allocating sparse objects. A delayed write feature is used for writing certain objects into non-volatile storage. Checkpoints can be retained as read-only versions of the file system. Modifications to the file system are accomplished without affecting the contents of retained checkpoints. The file system can be reverted to a retained checkpoint. Multiple file servers can be interconnected as a cluster, and each file server stores requests from another file server. Interconnections between file servers can be dynamically modified. A distributed locking mechanism is used to control access to file system objects stored by the file servers. | 10-25-2012 |
20130290256 | System and Method for Managing User Data in a Plurality of Storage Appliances Over a Wide Area Network for Collaboration, Protection, Publication, or Sharing - In various embodiments, the present invention relates to a method of operating a server to manage user data in a plurality of storage appliances. The method involves establishing in a database system, via the server, information for each registered user; establishing and storing in the database system a set of relationships, based on designations by the users, among registered storage appliances and container designations; and using a central service running on the server to deliver storage appliance-container relationship data to the storage appliances so as to enable the appliances to substantiate the containers therein, and to replicate user data with other storage appliances that have substantiated corresponding containers, in a manner consistent with the stored relationships, and wherein the central service operates without interaction with user data stored in the containers. | 10-31-2013 |
20130290464 | System and Method for Socially Organized Storage and Shared Access to Storage Appliances - In various embodiments, the present invention relates to systems and methods for managing user data in a plurality of storage appliances coupled to a wide area network. In some embodiments, the present invention relates to systems and methods that allow users to view and manipulate files in a shared virtual container. In other embodiments, the present invention also relates to systems and methods that allow users to access virtual containers located on storage appliances that are owned by other users. | 10-31-2013 |
20140074808 | Apparatus for Managing a Plurality of Root Nodes for File Systems - Apparatus for managing a plurality of root nodes may include a file server coupled to a storage device, wherein a first root node is operable to identify a previous version of an object of a file system and to relate to a plurality of data blocks forming a portion of the object, a second root node is operable to identify a current version of the object and to relate to a data block of the plurality of data blocks and a new data block of the object, and the storage device is operable to store the plurality of data blocks and the new data block. Apparatus for managing a plurality of root nodes alternatively may include a file system board operable to manage a plurality of root nodes, a first root node being operable to identify the a previous version of a file system and to relate to a plurality of data blocks of the file system, and a second root node being operable to identify the a current version of the file system and to relate to a data block of the plurality of data blocks and a new data block of the file system. | 03-13-2014 |
20140108709 | File Server Node with Non-Volatile Memory Processing Module Coupled to Cluster File Server Node - Apparatus includes a file server node having (i) a first interface operable to communicate with a network and receiving a network request via network, (ii) a non-volatile memory operable to temporarily store a request related to the network request received by the first interface, (iii) a second interface operable to be coupled to the storage device for storing the request, and (iv) a non-volatile memory processing module, coupled to the first interface, the non-volatile memory and the second interface, and operable to be coupled to another file server node, so that the request can be sent to the non-volatile memory, the second interface and the another file server node after the non-volatile memory processing module receives the file system request. | 04-17-2014 |
Patent application number | Description | Published |
20140217679 | Gasket with High Temperature Coating - A method of making a gasket having a high temperature coating that includes obtaining a substrate formed from a metallic material and having the shape of a gasket, applying a nanoparticle suspension over the outer surfaces of the substrate, and heating the substrate to a first elevated temperature to form an undercoat layer of a self-protective oxide coating. The method also includes applying a liquid comprising boron nitride over the undercoat layer and drying the boron nitride liquid at a second elevated temperature to form an overcoat layer. | 08-07-2014 |
20140238648 | Lightweight Thermal Shield - A method of making a lightweight thermal shield that includes obtaining a mold having a shaped support screen with a molding surface configured to allow the passage of air and moisture therethrough, and with the mold being adapted for drawing a vacuum from behind the support screen. The method also includes applying a wet insulation material onto the molding surface of the support screen and drawing a vacuum to withdraw moisture through the support screen and consolidate a layer of insulation material on top the molding surface. The method further includes removing the consolidated layer of insulation material from off the molding surface, installing the consolidated layer of insulation material into an outer shell layer, and drying the consolidated layer of insulation material within the outer shell layer to form a lightweight core insulation layer. | 08-28-2014 |
20140263369 | INSULATING CONTAINER AND METHODS OF MAKING AN INSULATING CONTAINER - An insulating container for controlling the transfer of heat from a hot object contained therein, the insulating container including a first half-shell and a second half-shell configured to couple together to form a sealed enclosure. The container further includes a first insert and a second insert sized and shaped to be received within the first half shell and the second half shell, respectively, and having inner surfaces that are shaped to surround and substantially conform to the hot object enclosed within the sealed enclosure, and wherein the first insert and the second insert are built up from a plurality of planar pieces of insulating material. | 09-18-2014 |