Chandra
Chandra Anupam, Schaumburg, IL US
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20080275798 | Evergreen contract billing & in life contract management system and method - The present invention provides an improved billing and contract management method and a computerized enterprise resource management system for processing and management of rent-producing financial products, such as contracts and leases that are past the initial end term date, and that have not been renegotiated or extended, or, in other words, that have entered the “evergreen” period. Among other things, the method and computerized system of the present invention integrate processing of the “evergreen” contracts with a proprietary generalized ERP software product/solution such as Oracle™ E-Business suite's Lease Management system, and supplement the processing of regular contracts with the “evergreen” contract authoring and booking, processing, validation, billing, accounting, collections, modification and audit trailing of the changes made to the “evergreen” contract terms. | 11-06-2008 |
Chandra Balasubrmanian, Mentor-On-The-Lake, OH US
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20110288965 | DYNAMIC PIN PAD FOR CREDIT/DEBIT/ OTHER ELECTRONIC TRANSACTIONS - A method is provided for authenticating debit card transactions engaged in by a cardholder on a communications network. The method includes: a) establishing a connection over the network with a client being used by the cardholder to engage in a transaction on the network; b) providing over the connection to the client a web page containing a keypad ( | 11-24-2011 |
Chandra Bodapati, Saratoga, CA US
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20090049010 | Method and system to enable domain specific search - A method and a computer system to enable domain specific search is disclosed. The present invention enables creation and sharing of domain specific search scripts, where search intelligence relating to domain and search engines is encapsulated in a parameterized domain specific search script. The system provides a customizable knowledge base to be used to configure the parameters specific to a chosen domain. Users can parameterized search scripts and configure search scripts according to their search needs. Users can use search scripts to perform complex domain specific searches by specifying input search string and without having to worry about refining results. The system uses the parameterized search scripts and configuration information along with user input search string to build search engine independent and search engine dependent queries from one or more search engines to provide relevant results to user. | 02-19-2009 |
20100005048 | Detecting duplicate records - A method for finding duplicates by matching group of fields in records is disclosed. The method comprises standardizing data using field specific knowledge base; extracting at least part of one or more related fields of records; applying a matching attribute function to generate keys on the “comparable” field part extracted data; generating record level keys using generated field level keys; clustering the records based on generated record level keys; identifying reference record for each cluster identified; and calculating matching percentage for each record in a cluster with respect to reference record of the cluster. Devices and systems are disclosed that enable the method for finding duplicates. | 01-07-2010 |
20100312837 | Methods and systems for determining email addresses - Disclosed herein is a method and system for a user to find an email address using the Internet. The user inputs the information that he wants to be verified or completed. A seeking unit determines the missing fields in the input information. The seeking unit may determine the missing information in the email address from various sources on the Internet, using a set of rules. The rules may be specified by the user or present in the database. The obtained search results are ranked by a ranking unit, based on the relevance of the scores. The seeking unit may also display the found email information along with the ranks to the user. The user has the option to sort the email information. The user may then select the most accurate email information, according to him, which is then used to populate the field in the information. | 12-09-2010 |
Chandra Bontu, Nepean CA
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20110261786 | RESTRICTING HANDOVER OF A MOBILE STATION - A base station communicates, with a mobile station, data associated with a packet-switched session in which the mobile station is involved. In response to a handover request from the mobile station, the base station accesses information provisioned for the mobile station to determine whether the mobile station is to be subjected to mobility restriction. Based on the accessed information, the base station determines whether to allow handover of the mobile station. A message is sent to the mobile station to indicate that the requested handover is not allowed if the base station determines that the requested handover is not allowed. | 10-27-2011 |
20130028233 | Allocating Resources in a Frequency-Time Space to Mobile Station Data - To allocate resources in an orthogonal frequency domain multiple access (OFDMA) system, two-dimensional rectangular regions are assigned in a frequency-time space to data bursts associated with mobile stations. At least one data burst does not fit in an available space in the frequency-time space is determined. In response to the determining, the assigned two-dimensional rectangular regions are reshaped. | 01-31-2013 |
20160037518 | Allocating Resources in a Frequency-Time Space to Mobile Station Data - To allocate resources in an orthogonal frequency domain multiple access (OFDMA) system, two-dimensional rectangular regions are assigned in a frequency-time space to data bursts associated with mobile stations. At least one data burst does not fit in an available space in the frequency-time space is determined. In response to the determining, the assigned two-dimensional rectangular regions are reshaped. | 02-04-2016 |
Chandra Bontu, Kanata CA
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20130142100 | METHOD AND APPARATUS FOR DISTRIBUTED RADIO RESOURCE MANAGEMENT FOR INTERCELL INTERFERENCE COORDINATION - A method at a user equipment and the user equipment, the method: obtaining an event having event conditions from system information multicasts of a plurality of network nodes; and sending an uplink message to at least one network node for any event whose conditions are satisfied utilizing resources allocated for the event. Also, a method at a network node and the network node, the method multicasting an event having event conditions to a plurality of user equipments; receiving a communication from a user equipment attached to the said network node or any neighbor network nodes, said communication providing an indication that the event conditions are met at the user equipment; compiling statistics, based on the receiving, of network conditions; and performing resource allocation based on the compiled statistics. | 06-06-2013 |
Chandra Dasaraju, Hyderabad-16 IN
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20140007177 | SECURE AUTHENTICATION USING MEMORY CARDS | 01-02-2014 |
Chandra Elcar, San Francisco, CA US
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20150363796 | SYSTEM AND METHOD FOR FILTERING SOCIAL MEDIA MESSAGES FOR PRESENTATION ON DIGITAL SIGNAGE SYSTEMS - A method for retrieving filtering social media messages from a local retailer's social media accounts. The filtering of social media messages retains localized content for the particular retail location and provides the social media content in a format suitable for display on the retail store's digital signage display devices. | 12-17-2015 |
Chandra Guntakala, Austin, TX US
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20140201375 | METHOD, APPARATUS AND SYSTEM PERTAINING TO CLOUD COMPUTING - The present disclosure outlines a system, method, and apparatus for the design of network services, including the automatic sourcing an aggregating of data on the available resources. In a further aspect, the present disclosure outlines a system, method, and apparatus for the allocation of cloud resources. In yet a further aspect, the present disclosure outlines a system, method, and apparatus for redirecting traffic through an alternative gateway. | 07-17-2014 |
Chandra Gupta, Bochum DE
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20080205318 | Apparatus, method and computer program product providing power optimization in battery powered communication devices - A method includes determining, based on a received network device resource allocation for an impending operational period, whether a power saving mode can be entered, and if the power saving mode can be entered, selectively controlling at least one of clock signals and power supply voltages of at least a baseband portion of a receiver. Also disclosed is an apparatus that operates in accordance with the method. | 08-28-2008 |
20080232498 | RADIO RECEIVER OR TRANSMITTER AND METHOD FOR REDUCING AN IQ GAIN IMBALANCE - A radio receiver includes an in-phase channel and a quadrature channel, the channels being provided in parallel at a respective input with quadrature modulated radio frequency signals; and an error correction loop for detecting and correcting an imbalance in gain between at least part of the in-phase channel and a corresponding part of the quadrature channel, wherein the error correction loop comprises: a detector adapted to calculate Error_det | 09-25-2008 |
Chandra Haripin, San Marcos, CA US
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20150099375 | Methods for Depositing Silicon Nitride Films - Described herein are methods for forming silicon nitride films. In one aspect, there is provided a method of forming a silicon nitride film comprising the steps of: providing a substrate in a reactor; introducing into the reactor an at least one organoaminosilane having a least one SiH | 04-09-2015 |
Chandra Jalluri, Canton, MI US
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20120325321 | TOOL LUBRICATION DELIVERY MONITORING SYSTEM AND METHOD - A tool lubrication delivery monitoring system and a method of control. An accelerometer is provided to detect a position of a valve and fluid flow through the valve. Accelerometer data may be compared to a baseline profile to determine whether fluid flow or valve operation is within established parameters. | 12-27-2012 |
Chandra Jonelagadda, Kirkland, WA US
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20160085866 | SYSTEM FOR PERFORMING TEXT MINING AND TOPIC DISCOVERY FOR ANTICIPATORY IDENTIFICATION OF EMERGING TRENDS - This disclosure describes a system that facilitates analyzing a broad and continuously updated sample of recent written communications for the purpose of identifying emerging and important news and topic developments before they attract broad attention. The system continuously discovers topics and relationships between topics in the written communications as the communications are received. Individual topics and topic relationships are continuously analyzed for the purpose of detecting changes in the frequency and manner in which the topics are addressed and changes in the content that accompanies the topics. The system uses this analysis as the basis for identifying certain topics and the communications that address them as emerging, and therefore, important. The system uses a display feature to highlight these topics and communications for a user to review or investigate further. | 03-24-2016 |
Chandra Kamalakantha, Plano, TX US
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20100023853 | WINDOWS PRESENTATION FOUNDATION BASED UI GENERATION FOR ABSTRACT WSDLS - Systems and method are disclosed for the automated generation of user interfaces and applications. These methods include selecting a mark up language document for creating an application, and obtaining user input for creating the user interface. These methods also include parsing the mark up language document to obtain at least one server parameter for the application, and using previously generated code to create a user interface for the application. This application can be stored in a computer readable medium. | 01-28-2010 |
20150347093 | Provisioning Tools for Application Development - An exemplary embodiment of the present invention may include a method of provisioning tools for application development. The method may include receiving parameters of a project. The method ma also include provisioning components through a network based on the parameters, the components including a source code management module to receive code related to the project, a continuous integration module to maintain code integration, and a virtual machine installed on a client device to enable a user to interact with other components. The method may also include communicatively coupling each of the source code management module, the continuous integration module, and the virtual machine to each other. | 12-03-2015 |
Chandra Kambhamettu, Newark, DE US
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20090315910 | SYSTEMS AND METHODS FOR OBTAINING AN IMAGE ALPHA MATTE - Methods and systems for obtaining an alpha matte for an image are disclosed. First and second known portions of an image are determined. The alpha matte for the image is estimated based on an initial fuzzy connectedness (FC) determination between the entire image and the first and second known portions. A third known portion is obtained. The estimated alpha matte for the image is refined based on a subsequent FC determination between a subset of the image and the first, second, and third known portions for the subset of the image and the initial FC determination for a remainder of the image. | 12-24-2009 |
20140022358 | PRISM CAMERA METHODS, APPARATUS, AND SYSTEMS - Methods, system, and apparatus for generating depth maps are described. A depth map may be generated by obtaining a transformation for a prism camera having a still image capture mode and a video mode (the transformation based on the difference between the still image transfer mode and the video mode), capturing a multi-view still image with the camera, capturing multi-view video images with the camera, and generating a resolved video depth map from the transformation, the multi-view still image, and the multi-view video. The depth map may be converted to a 3D structure. Multiple resolved 3D structures from prism camera apparatus may be combined to generate volumetric reconstruction of the scene. | 01-23-2014 |
Chandra Khandavalli, Livermore, CA US
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20130127541 | Analog Pre-distortion Linearizer - An analog pre-distortion linearizer having predetermined gain and phase characteristics as a function of input RF signal power is disclosed. The linearizer comprises a core circuit comprising an input terminal configured to receive an input RF signal; an output terminal configured to provide a processed version of that signal; a transistor having a gate, a drain, and a source; and a feedback circuit, presenting an impedance at the frequency of the RF signal, connected to the transistor. The gate is connected to the input terminal and the drain is connected to the output terminal. First and second dc bias voltages applied to the gate and drain respectively cause the transistor to operate at a quiescent bias point in a saturated region of the transistor I-V plane. The quiescent bias point and the impedance are selected such that the linearizer has the predetermined gain and phase characteristics. | 05-23-2013 |
Chandra Kumar, Karnataka IN
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20100167733 | INTERACTIVE MANAGEMENT OF WIRELESS WAN (WWAN) MOBILE DEVICES - A system and methods for allowing an enterprise management system to provision and configure a WWAN communication device on a managed network without incurring the tedious task of manually entering all the configuration information for every WWAN communication device on the enterprise management system. A dedicated communication link is provided with a standard communication protocol so each WWAN device can communicate with a carrier server and have the carrier server acts as a validation point and communication bridge to the enterprise management server until the WWAN communication device is configured for management by the enterprise management server. | 07-01-2010 |
Chandra Pinjala, San Jose, CA US
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20140237291 | USING SHARED PINS IN A CONCURRENT TEST EXECUTION ENVIRONMENT - A method for using shared pins in a concurrent test execution environment is disclosed. The method relates to scheduling tests in concurrently executing test flows for automated test equipment (ATE) in a way so that resources can be shared between the test flows. The method comprises determining if any of a plurality of splits used by a first test contains at least one resource that is shared, wherein the first test and a second test are sequenced for execution in two separate concurrently executing test flows. The method further comprises determining if the first test should execute before the second test if the split is associated with resources required by both the second and first tests. Finally the method comprises reserving the split containing the at least one shared resource for access by the first test before beginning execution of the first test. | 08-21-2014 |
20140324378 | AUTOMATED GENERATION OF A TEST CLASS PRE-HEADER FROM AN INTERACTIVE GRAPHICAL USER INTERFACE - A method for performing tests using automated test equipment (ATE) is presented. The method comprises obtaining information concerning a test class using a graphical user interface. Further, it comprises generating a first header file automatically, wherein the first header file comprises the information concerning the test class. Next, it comprises importing the first header file into a test plan operable to execute using a tester operating system wherein the test plan comprises instances of the test class. It further comprises, generating a second header file from the first header file automatically, wherein the second header file is a header file for the test class. The method also comprises validating the test plan using the tester operating system. Finally, the method comprises loading the test plan and a compiled module onto the tester operating system for execution, wherein the compiled module is a compiled translation of the test class. | 10-30-2014 |
Chandra Pisupati, Mountain View, CA US
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20120185795 | Automatic Management of the Visual Space while Performing a Task - A graphical user interface and method for displaying on an agent's desktop. The graphical user interface of the present invention being capable of automatically displaying, in a designated area, a managed application according to a workflow. The graphical user interface of the present invention also includes the ability to control the display of managed applications manually. Further, the graphical user interface and method of the present invention allows an Agent access to non-managed applications without restricting the agent's access to the managed applications. | 07-19-2012 |
Chandra Pokhrel, Thunder Bay CA
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20130221241 | SYSTEMS AND METHODS FOR RESETTING PHOTOCONDUCTIVE X-RAY IMAGING DETECTORS - Systems and methods of resetting a blocking-type photoconductive imaging detector are provided. In one embodiment, after having obtained an image, the imaging detector may be reset by applying a reversed bias potential difference and illuminating the imaging radiation detector with photoexcitation radiation. The photoexcitation radiation has a wavelength selected to excite mobile charges within the photoconductive layer and a spatial intensity profile related to the measured image for neutralizing the trapped charges in a spatially compensated manner. In another embodiment, a photoionizing beam is directed onto an x-ray light valve having a liquid crystal layer in contact with a photoconductive layer. The beam passes through an optically transmissive surface of the x-ray light valve and photoionizes a species within the liquid crystal layer, generating mobile charged entities that at least partially neutralize charges trapped at the interface, improving the performance of the x-ray light valve when performing subsequent x-ray imaging. | 08-29-2013 |
Chandra Praphul, Bangalore Karnataka IN
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20130290911 | METHOD AND SYSTEM FOR MULTIMODAL AND GESTURAL CONTROL - Embodiments of the present invention disclose a multimodal and gestural control system. According to one embodiment, the multimodal and gestural control system is configured to detect a gesture command from a user via at least one device of a plurality of devices. A control operation and a destination device are both determined based on the gesture command such that the determined control operation is executed on the determined destination device. | 10-31-2013 |
Chandra Sreeraman, East Brunswick, NJ US
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20140237295 | SYSTEM AND METHOD FOR AUTOMATING TESTING OF COMPUTERS - An application under test may be run in a test mode that receives a series of test scenarios and produces a set of test results under the control of a verification application. The verification application utilizes “typed-data” (i.e., data having known types that are associated with the data itself, e.g., XML-based data) such that a number of parameters can be set for each event and a number of result parameters can be checked for each result in at least one script. A series of scripts can be combined into an action file that may invoke scripts and override parameters within the invoked scripts. The events can be sent and received using a number of messaging protocols and communications adapters. | 08-21-2014 |
Chandra Srivastava, San Francisco, CA US
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20160125458 | VALUE-ADDED SERVICES DATA AND PROTOCOL AND TRANSACTIONS INVOLVING VEHICLE SPECIFIC DATA - A method for enabling a value-added transaction involving a vehicle and a merchant via a mobile device is disclosed. Merchant information may be broadcasted from a merchant terminal. Vehicle specific data may be received at the merchant terminal identifying the vehicle in response to the broadcasted merchant information. Transaction data may be provided to the mobile device to initiate an intended transaction. Payment data may be received from the mobile device at the merchant terminal in response to the provided transaction data. Before completing the intended transaction, a value-added transaction offer may be provided to the mobile device. In response to the provided value-added transaction offer, an acceptance of the value-added transaction offer may be received. The intended transaction and the value-added transaction offer may be completed as a single transaction. | 05-05-2016 |
Chandra Tupelly, San Ramon, CA US
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20120194496 | APPARATUS AND METHOD FOR SUPPORTING A MECHANICAL LAYER - This disclosure provides systems, methods and apparatuses for supporting a mechanical layer. In one aspect, an electromechanical systems device includes a substrate, a mechanical layer, and a post positioned on the substrate for supporting the mechanical layer. The mechanical layer is spaced from the substrate and defines one side of a gap between the mechanical layer and the substrate, and the mechanical layer is movable in the gap between an actuated position and a relaxed position. The post includes a wing portion in contact with a portion of the mechanical layer, the wing portion positioned between the gap and the mechanical layer. The wing portion can include a plurality of layers configured to control the curvature of the mechanical layer. | 08-02-2012 |
Chandra Vargeese, Blue Bell, PA US
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20090023675 | RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA) - The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against target nucleic acid sequences. The small nucleic acid molecules are useful in the treatment of any disease or condition that responds to modulation of gene expression or activity in a cell, tissue, or organism. | 01-22-2009 |
20090048197 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), short hairpin RNA (shRNA), and RNAi inhibitor molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 02-19-2009 |
Chandra Vargeese US
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20110200582 | LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM - Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). | 08-18-2011 |
20160106842 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS - This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R | 04-21-2016 |
Chandra Vargeese, Cambridge, MA US
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20140309277 | LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM - Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). | 10-16-2014 |
20160106842 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS - This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R | 04-21-2016 |
Chandra Vargeese, Broomfield, CO US
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20080207542 | RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA) - The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity. The present invention is also directed to compounds, compositions, and methods relating to traits, diseases and conditions that respond to the modulation of expression and/or activity of genes involved in gene expression pathways or other cellular processes that mediate the maintenance or development of such traits, diseases and conditions. Specifically, the invention relates to double stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against gene expression, including cocktails of such small nucleic acid molecules and lipid nanoparticle (LNP) formulations of such small nucleic acid molecules. The present invention also relates to small nucleic acid molecules, such as siNA, siRNA, and others that can inhibit the function of endogenous RNA molecules, such as endogenous micro-RNA (miRNA) (e.g, miRNA inhibitors) or endogenous short interfering RNA (siRNA), (e.g., siRNA inhibitors) or that can inhibit the function of RISC (e.g., RISC inhibitors), to modulate gene expression by interfering with the regulatory function of such endogenous RNAs or proteins associated with such endogenous RNAs (e.g., RISC), including cocktails of such small nucleic acid molecules and lipid nanoparticle (LNP) formulations of such small nucleic acid molecules. Such small nucleic acid molecules and are useful, for example, in providing compositions to prevent, inhibit, or reduce diseases, traits and conditions that are associated with gene expression or activity in a subject or organism. | 08-28-2008 |
20080249040 | RNA interference mediated inhibition of sterol regulatory element binding protein 1 (SREBP1) gene expression using short interfering nucleic acid (siNA) - The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of Sterol Regulatory Element-Binding Protein 1 (SREBP1) gene expression and/or activity. The present invention is also directed to compounds, compositions, and methods relating to traits, diseases and conditions that respond to the modulation of expression and/or activity of genes involved in Sterol Regulatory Element-Binding Protein 1 (SREBP1) gene expression pathways or other cellular processes that mediate the maintenance or development of such traits, diseases and conditions. Specifically, the invention relates to double stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against Sterol Regulatory Element-Binding Protein 1 (SREBP1) gene expression, including cocktails of such small nucleic acid molecules and lipid nanoparticle (LNP) formulations of such small nucleic acid molecules. The present invention also relates to small nucleic acid molecules, such as siNA, siRNA, and others that can inhibit the function of endogenous RNA molecules, such as endogenous micro-RNA (miRNA) (e.g, miRNA inhibitors) or endogenous short interfering RNA (siRNA), (e.g., siRNA inhibitors) or that can inhibit the function of RISC (e.g., RISC inhibitors), to modulate SREBP1 gene expression by interfering with the regulatory function of such endogenous RNAs or proteins associated with such endogenous RNAs (e.g., RISC), including cocktails of such small nucleic acid molecules and lipid nanoparticle (LNP) formulations of such small nucleic acid molecules. Such small nucleic acid molecules and are useful, for example, in providing compositions to prevent, inhibit, or reduce metabolic diseases traits and conditions, including but not limited to hyperlipidemia, hypercholesterolemia, cardiovascular disease, atherosclerosis, hypertension, diabetis (e.g., type I and/or type II diabetis), insulin resistance, obesity and/or other disease states, conditions, or traits associated with SREBP1 gene expression or activity in a subject or organism. | 10-09-2008 |
20090137500 | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) - The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against target nucleic acid sequences. The small nucleic acid molecules are useful in the treatment of any disease or condition that responds to modulation of gene expression or activity in a cell, tissue, or organism. | 05-28-2009 |
20100063308 | LIPID NANOPARTICLE BASED COMPOSITIONS AND METHODS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 03-11-2010 |
20150105445 | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) - The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against target nucleic acid sequences. The small nucleic acid molecules are useful in the treatment of any disease or condition that responds to modulation of gene expression or activity in a cell, tissue, or organism. | 04-16-2015 |
Chandra Vemavarapu, Hillsborough, NJ US
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20130045245 | APIXABAN FORMULATIONS - Compositions comprising crystalline apixaban particles having a D | 02-21-2013 |
20150119317 | ORAL SOLID DOSAGE FORMULATION OF 1,1-DIMETHYLETHYL [(1S)-1-CARBAMOYL)PYRROLIDIN-1-YL]CARBONYL}-2,2-DIMETHYLPROPYL]CARBAMATE - The present invention is directed to an oral solid dosage formulation of Asunaprevir, 1,1-dimethylethyl[(1S)-1-{[(2S,4R)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}carbamoyl)pyrrolidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate, and to methods of using the formulation in the treatment and/or inhibition of the hepatitis C virus and infections caused thereby. | 04-30-2015 |
Chandra Vimlesh, Pohang-Si KR
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20130099153 | HYBRID MATERIAL COMPRISING GRAPHENE AND IRON OXIDE, METHOD FOR MANUFACTURING THE SAME, AND APPARATUS FOR TREATING WASTE WATER USING THE SAME - A hybrid material including graphene and iron oxide, a method of manufacturing the same, and an apparatus for treating waste water using the same are provided. A hybrid material having magnetic properties and high dispersibility and including graphene and iron oxide may be effectively used for removing a heavy metal in waste water. | 04-25-2013 |
20140374646 | HYBRID MATERIAL COMPRISING GRAPHENE AND IRON OXIDE, METHOD FOR MANUFACTURING THE SAME, AND APPARATUS FOR TREATING WASTE WATER USING THE SAME - A method of manufacturing a hybrid material including graphene and iron oxide includes (a) preparing graphene oxide, (b) dispersing the graphene oxide in water to prepare a first dispersion, (c) adding divalent iron (Fe) and trivalent iron (Fe) to the first dispersion to prepare a second dispersion, (d) adjusting pH of the second dispersion to be about 8 to about 11 at about 25° C., (e) increasing the temperature of the second dispersion obtained from the (d) process up to about 80 to about 110° C., and adding a reducing agent to the second dispersion obtained from the (e) process to prepare a uniform and fine hybrid material including graphene and iron oxide. | 12-25-2014 |
Chandra Warrrier, Schaumburg, IL US
Patent application number | Description | Published |
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20080291869 | Routing Method for Mobile Wireless Nodes Having Overlapping Internet Protocol Home Addresses - In mobile IP wireless data networking, methods are described for correctly routing packets through a foreign agent to or from wireless nodes where the wireless nodes have the same home network IP address. Instead of using normal IP routing, the foreign agent uniquely identifies the wireless node's home network IP address and home agent IP address with a PPP link address associated with a PPP link between the foreign agent and the wireless node. This association between PPP link addresses, home agent IP addresses, and home network IP addresses, is preferably implemented in software as a table stored in the foreign agent. The routing of packets through the foreign agent to the mobile nodes is performed by reference to the table. The table allows the foreign agent to correctly and efficiently route packets in the situation where multiple wireless nodes are registered with the foreign agent, but more than one of the wireless nodes have the same home network IP address. | 11-27-2008 |
Chandra Yeleshwarapu, Foster City, CA US
Patent application number | Description | Published |
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20110087626 | PRODUCT CLASSIFICATION IN PROCUREMENT SYSTEMS - Various embodiments provide solutions to assist in the classification of products in a procurement system. The tools provided by various embodiments include, without limitation, methods, systems, and/or software products. Merely by way of example, a method might comprise one or more procedures, any or all of which are executed by a computer system. Correspondingly, an embodiment might provide a computer system configured with instructions to perform one or more procedures in accordance with methods provided by various other embodiments. Similarly, a computer program might comprise a set of instructions that are executable by a computer system (and/or a processor therein) to perform such operations. In many cases, such software programs are encoded on physical and/or tangible computer readable media (such as, to name but a few examples, optical media, magnetic media, and/or the like). | 04-14-2011 |
20110252463 | METHOD AND SYSTEM FOR PROVIDING ENTERPRISE PROCUREMENT NETWORK - According to an embodiment, the present invention provides a computer system. The computer system includes one or more processors and a computer-readable medium in communication with the one or more processors. The computer system also includes an enterprise social network system, implemented by an enterprise application stored on the computer-readable storage medium, for retrieving and providing procurement information from a plurality of social network entities associated with the enterprise social network system, the enterprise social network system comprising a set of instructions executable by the one or more processors to perform one or more operations. The set of instructions includes instructions for providing, at a computer system, a user interface for receiving input from a user. The set of instructions includes instructions for providing a user profile for a user, the user profile being stored at the enterprise social network system, the user being associated with a plurality of network entities, the user profile including a first plurality of user attributes. | 10-13-2011 |
20110302102 | COMMUNITY RATING AND RANKING IN ENTERPRISE APPLICATIONS - The present invention is directed to methods and systems which provide a comprehensive rating and ranking of products and services. Furthermore, aspects of the present invention provides a complete review of products and services, as well as rankings of semantic and non-semantic reviews, which provides a “true” reflection of a product and/or service. As such, a calculation of a product/supplier rating based on all of its social entity contexts, is performed. This takes into account factors like, author (of social entity context) credibility, non-semantic (direct) rating, semantic rating calculated from the textual content of the social entity context, the community based credibility of the social entity context, and the like. Then, the community based credibility of a given social entity context is in turn calculated. | 12-08-2011 |
20120030160 | METHOD AND SYSTEM FOR PROVIDING DECISION MAKING BASED ON SENSE AND RESPOND - According to an embodiment, the present invention provides a method for providing automated decision in response to one or more responses. The method includes providing, at a computer system, a user interface for receiving input from a user. The method also includes detecting a first event. The method further includes receiving a first set of attributes associated with the first event. Also, the method includes processing the first set of attributes. The method additionally includes analyzing the first set of attributes using at least pattern recognition. The method includes determining a first context for the first event based at least on the first set of attributes. | 02-02-2012 |