Patent application number | Description | Published |
20080280928 | Pyrrolopyrimidine and Pyrrolopyridine Derivatives Substituted with a Cyclic Amino Group As Crf Antagonists - [PROBLEM TO BE SOLVED] An object of the present invention is to provide an antagonist against CRF receptors and/or an agonist for δ receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc.
| 11-13-2008 |
20080287397 | Pyrrolopyrimidine Derivatives Substituted with Cyclic Amino Group - An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. This problem can be solved with a pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] below which has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved. | 11-20-2008 |
20090111835 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP - An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A thienopyrimidine or thienopyridine derivative substituted with a cyclic amino group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved. | 04-30-2009 |
20090234162 | Radioactive Halogen-Labeled Phenyloxyaniline Derivatives - A radioactive halogen-labeled phenyoxyaniline derivative represented by the following formula: wherein R | 09-17-2009 |
20100298561 | 2-AMINO-BICYCLO(3.1.0) HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE - A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high activity in oral administration A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative represented by formula [I] | 11-25-2010 |
20110124862 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH A CYCLIC AMINO GROUP AS CRF ANTAGONISTS - [Problem to be Solved] An object of the present invention is to provide an antagonist against CRF receptors and/or an agonist for δ receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc. | 05-26-2011 |
20110130364 | PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP - An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. This problem can be solved with a pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] below which has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved. | 06-02-2011 |
20110137031 | PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES - An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A pyrrolopyrimidine or pyrrolotriazine derivative substituted with a carbamoyl group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved. | 06-09-2011 |
20120004232 | 2-AMINO-BICYCLO(3.1.0) HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE - A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high activity in oral administration | 01-05-2012 |
20120028982 | 2-AMINO-BICYCLO[3.1.0]HEXANE-2, 6-DICARBOXYLIC ESTER DERIVATIVE - A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors and shows high activity in oral administration. A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative represented by formula [I] | 02-02-2012 |
Patent application number | Description | Published |
20090009056 | LIGHT-EMITTING APPARTUS - A light emitting apparatus capable of efficiently generating high luminance white light is provided. The present invention permits white light to be generated, without using low-emission efficiency white light emitters, by forming a light emitter layer | 01-08-2009 |
20090197171 | ELECTRIC STORAGE DEVICE - An electric storage device | 08-06-2009 |
20090197175 | ELECTRIC STORAGE DEVICE - An electric storage device | 08-06-2009 |
20090214955 | ELECTRIC STORAGE DEVICE, ELECTRODE, METHOD FOR FABRICATING ELECTRODE, AND MANAGEMENT METHOD - A mixture layer for an electrode is formed on a punched current collector. For example, the mixture layer is made of an active material, conductive assistant, binder, and the like. The mixture layer having the structure described above is formed into a slurry, for example, and applied onto the current collector. The applied mixture layer is dried to fabricate an electrode. The thus formed electrode is used to assemble an electric storage device. Upon the assembly, lithium ions are pre-doped into a negative electrode. The pre-doping time is determined according to air permeability of the electrodes. | 08-27-2009 |
20100221587 | WOUND-TYPE ELECTRIC STORAGE DEVICE - A positive electrode sheet including a positive electrode mixture layer formed on one surface is provided at one of the outermost layers of an electrode sheet group, while a positive electrode sheet including a positive electrode mixture layer formed at one surface is provided at the other outermost layer of the electrode sheet group. A negative electrode sheet including negative electrode mixture layers formed on both surfaces is provided between the positive electrode sheets. A lithium electrode sheet including metal lithium foils formed on both surfaces is overlapped onto the electrode sheet group formed by stacking the three sheets. When a wound-type electric storage device is produced, the electrode sheet group is wound together with the lithium electrode sheet. | 09-02-2010 |
20110236763 | ELECTRIC STORAGE DEVICE - In an electric storage device, lithium electrodes are disposed on respective outermost portions of an electrode laminated unit in which a positive electrode and a negative electrode are laminated alternately via positive/negative electrode separators. The lithium electrode includes lithium metal serving as a lithium ion supply source, and a lithium electrode separator (a non-woven fabric separator) constituted by a non-woven fabric that satisfies the following conditions: (a) an average fiber diameter of 0.1 μm to 10 μm; and (b) a thickness of 5 μm to 500 μm is provided. By forming the lithium electrode separator that contacts the lithium electrode including the lithium ion supply source from a non-woven fabric in this manner, a dramatic improvement can be achieved in the cycle characteristic of the electric storage device. | 09-29-2011 |
Patent application number | Description | Published |
20090005689 | ULTRASOUND ENDOSCOPE - An ultrasound endoscope including, at a distal end of an insertion portion to be inserted to a body cavity, a distal rigid portion arranged forward of a flexible tube portion, an ultrasound transducer portion for scanning a plane which is parallel to forward side of a longitudinal center axis L1 of the distal rigid portion, and a treatment instrument insertion channel port opening in a distal-side end face of the distal rigid portion, with a longitudinal center axis L4 being parallel to the longitudinal center axis L1 of the distal rigid portion. | 01-01-2009 |
20090281429 | HOOD FOR ULTRASOUND PROBE DEVICE AND ULTRASOUND PROBE DEVICE - An ultrasound probe device of the present invention includes an insertion section having an ultrasound probe, and a hood section which has a cylindrical shape having an opening portion at a distal end side and is disposed at the insertion section to surround the ultrasound probe, and is capable of decompressing a space surrounded by the hood section. | 11-12-2009 |
20090287080 | TREATMENT INSTRUMENT FOR ENDOSCOPE AND LYMPH NODE REMOVING METHOD - A treatment instrument for endoscope of the present invention includes a puncture needle having a barb. A lymph node removing method of the present invention includes: an insertion step, wherein an endoscope has an insertable insertion portion which is inserted into an esophagus or a trachea being a lumen inside the body of a subject; the step of inserting a distal end portion arranged at the tip of the insertion portion of the endoscope into the lumen; a confirmation step of confirming the position of a mediastinal lymph node by performing ultrasound scanning using an ultrasound transducer arranged at the distal end portion; an anchoring step of placing an anchoring device which has been inserted through a channel inside the insertion portion of the endoscope, on the mediastinal lymph node by performing the ultrasound scanning; a incision step of cutting a wall of the lumen to make a fistula; and a drawing-in step of drawing the mediastinal lymph node into the lumen with the anchoring device. | 11-19-2009 |
20100063392 | ULTRASOUND-GUIDED ABLATION METHOD AND ULTRASOUND-GUIDED ABLATION SYSTEM - An ultrasound-guided ablation method captures an objective area to be ablated in an ultrasound scan area of an ultrasound transducer and delineates the objective area on an ultrasound image; specifies an ablation target area to display the ablation target area with a margin necessary for ablating the objective area on the ultrasound image processed by an ultrasound observation device and displayed on a display device; ablates, by an ablation device, the ablation target area displayed on the ultrasound image; and checks, on the ultrasound image, that an ablated area ablated by the ablation device has reached the ablation target area displayed on the ultrasound image. | 03-11-2010 |
20100063401 | ULTRASOUND ENDOSCOPE SYSTEM AND ULTRASOUND OBSERVATION METHOD - When an ultrasound endoscope arrives at an objective area, a puncture needle is located in a scan area of a first ultrasound image. Thereby, an image of the puncture needle is delineated on the first ultrasound image. Furthermore, an ultrasound probe is inserted into the puncture needle and an ultrasound transducer of the ultrasound probe is arranged in the objective area through the puncture needle. Then, the ultrasound probe is driven and a second ultrasound image is delineated. Detailed observation inside the objective area in which the puncture needle is punctured is possible with the second ultrasound image. | 03-11-2010 |
20110313246 | TREATMENT INSTRUMENT FOR ENDOSCOPE AND METHOD OF HARVESTING LYMPH NODE - A treatment instrument for endoscope of the present invention includes a puncture needle having a barb. A lymph node removing method of the present invention includes: an insertion step, wherein an endoscope has an insertable insertion portion which is inserted into an esophagus or a trachea being a lumen inside the body of a subject; the step of inserting a distal end portion arranged at the tip of the insertion portion of the endoscope into the lumen; a confirmation step of confirming the position of a mediastinal lymph node by performing ultrasound scanning using an ultrasound transducer arranged at the distal end portion; an anchoring step of placing an anchoring device which has been inserted through a channel inside the insertion portion of the endoscope, on the mediastinal lymph node by performing the ultrasound scanning; a incision step of cutting a wall of the lumen to make a fistula; and a drawing-in step of drawing the mediastinal lymph node into the lumen with the anchoring device. | 12-22-2011 |
20120078094 | Ultrasound-Guided Ablation Method and Ultrasound-Guided Ablation System - An ultrasound-guided ablation method captures an objective area to be ablated in an ultrasound scan area of an ultrasound transducer and delineates the objective area on an ultrasound image; specifies an ablation target area to display the ablation target area with a margin necessary for ablating the objective area on the ultrasound image processed by an ultrasound observation device and displayed on a display device; ablates, by an ablation device, the ablation target area displayed on the ultrasound image; and checks, on the ultrasound image, that an ablated area ablated by the ablation device has reached the ablation target area displayed on the ultrasound image. | 03-29-2012 |
20120226223 | PROCEDURE - A procedure for forming an opening in a tubular organ surface while observing images from an endoscope introduced into a tubular organ through a natural opening, and performing observation and treatment of an organ in an abdominal cavity through the opening, including the steps of: inserting an endoscope into a target tubular organ through a natural opening of a subject; checking and identifying a region without other organs or blood vessels; inserting a perforating treatment instrument; perforating with the perforating treatment instrument; inserting the endoscope into the abdominal cavity through the perforated portion; inserting a surgical treatment instrument through the perforated portion; performing surgery; inserting a suturing instrument; and suturing the perforated portion, wherein the endoscope is replaced by an ultrasonic endoscope in at least one of the steps. | 09-06-2012 |
20120265057 | ULTRASOUND ENDOSCOPE SYSTEM AND ULTRASOUND OBSERVATION METHOD - When an ultrasound endoscope arrives at an objective area, a puncture needle is located in a scan area of a first ultrasound image. Thereby, an image of the puncture needle is delineated on the first ultrasound image. Furthermore, an ultrasound probe is inserted into the puncture needle and an ultrasound transducer of the ultrasound probe is arranged in the objective area through the puncture needle. Then, the ultrasound probe is driven and a second ultrasound image is delineated. Detailed observation inside the objective area in which the puncture needle is punctured is possible with the second ultrasound image. | 10-18-2012 |
Patent application number | Description | Published |
20120063157 | LIGHTING FIXTURE - A vehicular lighting fixture unit according to one aspect of the subject matter can include a projector lens placed on an optical axis extending in a vehicle front-rear direction. A light-emitting element can be placed between the projector lens and a rear-side focal point of the projector lens at a position lower than the optical axis so as to emit light substantially vertically upward. A phosphor can be placed so as to be closer to a vehicle rear side than the rear-side focal point. A first reflecting surface can be configured to reflect the light from the phosphor so as to condense the light toward the optical axis. A second reflecting surface can be placed substantially vertically above the light-emitting element at a position at which the second reflecting surface does not block the reflected light from the first reflecting surface. The second reflecting surface can be configured to reflect the light from the light-emitting element toward the phosphor. | 03-15-2012 |
20120140501 | VEHICLE LIGHT - A vehicle light can prevent color variations in a projected image. The vehicle light can include a light source, a wavelength conversion member including a phosphor configured to receive blue light having been emitted from the light source and then emitting white light, and a reflector having a reflection surface that reflects the white light having been emitted from the wavelength conversion member. The reflection surface of the reflector can have an optical structure that can diffuse the blue light incident on the reflection surface from the phosphor, reflect the blue light back to the phosphor, or allow the blue light to pass through the reflection surface to the area rearward thereof. | 06-07-2012 |
20120163009 | VEHICLE LIGHT - A vehicle light can prevent color variations of the projected image. The vehicle light can include a laser diode, a wavelength conversion member including a phosphor configured to receive blue light emitted from the laser diode and then emitting white light, a projection lens configured to project the white light emitted from the wavelength conversion member to provide forward illumination for a vehicle, and a diffusing portion provided to the projection lens, configured to diffuse the excitation light which is incident on the projection lens from the wavelength conversion member. | 06-28-2012 |
20120294023 | VEHICLE LIGHTING UNIT - A vehicle lighting unit that utilizes a semiconductor laser light source can suppress color unevenness of a light distribution pattern while ensuring the usefulness of the semiconductor laser light source. The vehicle lighting unit can include a semiconductor laser light source, a phosphor configured to receive blue light emitted from the semiconductor laser light source and emit white light by excitation, and a reflector configured to reflect the light emitted from the phosphor so that the light can be diffused wider in a right-to-left direction than in a vertical direction on the basis of a posture when the lighting unit is mounted on a vehicle body. Part of the blue light that is emitted from the semiconductor laser light source and reflected off a surface of the phosphor can be incident on the reflector with an elongated area in the right-to-left direction. | 11-22-2012 |
20130188376 | VEHICLE LIGHTING UNIT - A vehicle lighting unit can form a structure or mechanism for positioning and installing a light emitting device in a vehicle lighting unit main body. | 07-25-2013 |
20140085923 | LIGHT EMITTING DEVICE - A light emitting device can project high density laser light by collecting laser light to irradiate in a spotlight manner while remedying local brightness saturation and temperature quenching, and can suppress the lowering of efficiency due to such local brightness saturation and temperature quenching. The light emitting device can include an excitation light source for emitting excitation light; a wavelength conversion member including a diffusion layer and a wavelength conversion layer. The Device can include an optical system configured to collect the excitation light from the excitation light source to irradiate the first face with the collected excitation light in a spotlight manner. In the light emitting device, the diffusion layer can have a thickness that is set in such a manner that brightness distribution of the diffused light exiting through the second face does not include a local peak. | 03-27-2014 |
20140112012 | VEHICLE HEADLAMP - There is provided a vehicle headlamp that can be miniaturized and that can form a synthetic light distribution pattern (for example, a low-beam light distribution pattern) in which a hot zone is brighter. The vehicle headlamp that forms the synthetic light distribution pattern including the hot zone and a diffusion region diffused from the hot zone, includes at least one first lighting fixture unit including a laser light source and a first optical system that forms a first light distribution pattern to irradiate light forward from the laser light source and irradiate the hot zone, and at least one second lighting fixture unit including an LED light source and a second optical system that forms a second light distribution pattern to irradiate light forward from the LED light source and irradiate the diffusion region. | 04-24-2014 |
20140268846 | VEHICLE HEADLIGHT - A vehicle headlight can be configured such that the size of the vehicle headlight which includes a semiconductor laser element employed as a light source is reduced. The vehicle headlight can includes: a projection lens disposed on an optical axis extending in a front-to-rear direction of a vehicle body; a light-emitting device including a semiconductor laser element configured to emit a laser beam and a light-transmitting member configured to absorb and convert the wavelength of at least part of the laser beam from the semiconductor laser element; and a first reflection surface configured to reflect the light from the light-emitting device so as to transmit and project forward the resulting light through the projection lens. The vehicle headlight can further include: a light detection unit configured to detect a light beam of a specific color, the light detection unit being disposed between the projection lens and the light-emitting device and below the optical axis; a second reflection surface configured to reflect the light beam from the light-emitting device toward the light detection unit, the second reflection surface being disposed ahead of the front end of the first reflection surface; and a control unit configured to control the semiconductor laser element in accordance with a detection result provided by the light detection unit so that the semiconductor laser element does not emit the laser beam. | 09-18-2014 |
Patent application number | Description | Published |
20120268567 | THREE-DIMENSIONAL MEASUREMENT APPARATUS, PROCESSING METHOD, AND NON-TRANSITORY COMPUTER-READABLE STORAGE MEDIUM - A three-dimensional measurement apparatus selects points corresponding to geometric features of a three-dimensional shape model of a target object, projects a plurality of selected points corresponding to the geometric features onto a range image based on approximate values indicating the position and orientation of the target object and imaging parameters at the time of imaging of the range image, searches regions of predetermined ranges respectively from the plurality of projected points for geometric features on the range image which correspond to the geometric features of the three-dimensional shape model, and associates these geometric features with each other. The apparatus then calculates the position and orientation of the target object using differences of distances on a three-dimensional space between the geometric features of the three-dimensional shape model and those on the range image, which are associated with each other. | 10-25-2012 |
20120316820 | INFORMATION PROCESSING APPARATUS AND INFORMATION PROCESSING METHOD - An information processing apparatus includes an acquisition unit configured to acquire a plurality of positions on a surface of a measurement target object using information of light reflected from the measurement target object on which structured light is projected, a position of a light source of the structured light, and a position of a light reception unit configured to receive the reflected light and acquire the information of the reflected light, a calculation unit configured to acquire at least one of a position and a direction on the surface of the measurement target object based on the plurality of the positions, and a correction unit configured to correct at least one of the plurality of the positions based on information about an error in measurement for acquiring the plurality of the positions and at least one of the position and the direction on the surface of the measurement target object. | 12-13-2012 |
20130094706 | INFORMATION PROCESSING APPARATUS AND PROCESSING METHOD THEREOF - An information processing apparatus acquires a plurality of geometric features and normals at the respective geometric features from a target object arranged at the first position. The information processing apparatus also acquires a plurality of normals corresponding to the respective geometric features of the target object from a shape model for the target object that is arranged at the second position different from the first position. The information processing apparatus calculates direction differences between the acquired normals for respective pairs of corresponding geometric features of the target object and shape model. The information processing apparatus determines whether or not occlusion occurs at each geometric feature by comparing the calculated direction differences with each other. | 04-18-2013 |
20130121592 | POSITION AND ORIENTATION MEASUREMENT APPARATUS,POSITION AND ORIENTATION MEASUREMENT METHOD, AND STORAGE MEDIUM - An apparatus comprises: extraction means for extracting an occluded region in which illumination irradiated onto the target object is occluded in an obtained two-dimensional image; projection means for projecting a line segment that constitutes a three-dimensional model onto the two-dimensional image based on approximate values of position/orientation of the target object; association means for associating a point that constitutes the projected line segment with a point that constitutes an edge in the two-dimensional image; determination means for determining whether the associated point that constitutes an edge in the two-dimensional image is present within the occluded region; and measurement means for measuring the position/orientation of the target object based on a distance on the two-dimensional image between the point that constitutes the projected line segment and the point that constitutes the edge, the points being associated as the pair, and a determination result. | 05-16-2013 |
20130335751 | RANGE MEASUREMENT APPARATUS AND RANGE MEASUREMENT METHOD - A region projected with pattern light in an image sensed by an image sensing unit which senses an image of a target object projected with pattern light is specified. Geometric features of the target object are searched for from a region other than the region projected with the pattern light in the sensed image based on the specified region. A position and orientation of the target object are derived based on the searched geometric features of the target object and geometric features of a model of the target object. | 12-19-2013 |
20140293009 | INFORMATION PROCESSING APPARATUS AND INFORMATION PROCESSING METHOD - An image representing reflected light of structured light is acquired, distance information is calculated, from the image, and a measurement line map storing the distance information is generated. The structured light forms a plurality of measurement lines at discrete positions, and the measurement line map is formed as a two-dimensional array in which one dimension includes elements in a number corresponding to a number of the measurement lines, and another dimension includes elements in a number corresponding to a number of pixels of the image in a lengthwise direction of the measurement lines. | 10-02-2014 |
20150352719 | APPARATUS, METHOD FOR CONTROLLING APPARATUS, AND STORAGE MEDIUM - An apparatus comprises a holding unit configured to hold data related to a worker; an obtaining unit configured to obtain measurement data for recognizing the worker; a recognizing unit configured to recognize the worker based on the data related to the worker and the measurement data; a determination unit configured to determine work information about a work which the worker and a robot perform on a target object together, corresponding to the recognized worker, based on a physical feature of the recognized worker; and a controlling unit configured to control the robot based on the work information so that the worker and the robot perform a work on the target object together. | 12-10-2015 |