Blazar
Bruce Blazar, Golden Valley, MN US
Patent application number | Description | Published |
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20080274088 | Mapc Generation of Lung Tissue - The present invention relates to methods of improving function in lung tissue by administering a population of multipotent adult progenitor cells (“MAPCs”) or differentiated progeny thereof. | 11-06-2008 |
20080317740 | Use of Nk Cell Inhibition to Facilitate Persistence of Engrafted Mhc-I-Negative Cells - The present invention relates to the use of a means for inhibiting NK cell function to increase persistence and/or engraftment of MHC-I negative cells, such as MAPCs. | 12-25-2008 |
20100291678 | Regulatory T Cells and Their Use in Immunotherapy and Suppression of Autoimmune Responses - Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4 | 11-18-2010 |
20110243901 | Compositions and Methods for the Treatment of Lysosomal Storage Disorders - The present invention relates to methods for providing lysosomal enzymes to a subject by administering stem cells, preferably Multipotent Adult Progenitor Cells (MAPCs). The invention further relates to methods for treating lysosomal storage disorders by administering stem cells. | 10-06-2011 |
20120207727 | Regulatory T Cells and Their Use in Immunotherapy and Suppression of Autoimmune Responses - Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4 | 08-16-2012 |
20140072545 | GENERATION OF NATURAL KILLER CELLS AND LYMPHOID TISSUE INDUCER-LIKE (LTI-LIKE) NK-22 CELLS - The present invention relates generally to methods to prepare NK and LTi-like, NK22 cells from HSCs and uses of those cells. | 03-13-2014 |
20140212393 | Compositions and Methods for the Treatment of Lysosomal Storage Disorders - The present invention relates to methods for providing lysosomal enzymes to a subject by administering stem cells, preferably Multipotent Adult Progenitor Cells (MAPCs). The invention further relates to methods for treating lysosomal storage disorders by administering stem cells. | 07-31-2014 |
20140234267 | MAPC Generation of Lung Tissue - The present invention relates to methods of improving function in lung tissue by administering a population of multipotent adult progenitor cells (“MAPCs”) or differentiated progeny thereof. | 08-21-2014 |
20140256798 | TALEN-BASED GENE CORRECTION - The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders. | 09-11-2014 |
Bruce M. Blazar, Golden Valley, MN US
Patent application number | Description | Published |
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20130129686 | Reducing Inflammation Using Cell Therapy - The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component, including graft-versus-host disease. The invention is generally directed to reducing inflammation by administering cells that express and/or secrete prostaglandin E2 (PGE2). The invention is also directed to drug discovery methods to screen for agents that modulate the ability of the cells to express and/or secrete PGE2, such as PGE2 receptor agonists. The invention is also directed to cell banks that can be used to provide cells for administration to a subject, the banks comprising cells having desired levels of PGE2 expression and/or secretion. The invention is also generally directed to delivering cells directly to lymphohematopoietic tissue, such as spleen, lymph nodes, and bone marrow. The invention is, thus, also directed to a method for treating inflammation by administering cells directly into sites of lymphohematopoiesis, such as spleen, lymph nodes, and bone marrow. The administered cells include those that reduce the activation and/or proliferation of T-cells. Such cells may or may not express and/or secrete PGE2. | 05-23-2013 |
Joseph E. Blazar, Owensboro, KY US
Patent application number | Description | Published |
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20130019409 | COMFORT CUSTOMIZABLE PILLOW - Embodiments typically might relate to pillows that are comfort customizable based on user preference. For example, embodiments might include an outer casing and a self-inflating inner core. A user might adjust the firmness and/or thickness of the pillow by altering the amount of fluid, such as air, within the inner core. Typically such adjustments might be performed without use of a pump, given the self-inflating nature of the inner core, | 01-24-2013 |
20130074273 | WASHABLE MATTRESS TOPPER - Embodiments relate generally to a washable mattress topper. The washable mattress topper comprises a cushion element and a fabric cover enclosing and attached to the cushion element in a manner which divides the cushion element into a plurality of compartments. | 03-28-2013 |
20140082846 | WASHABLE FOAM PILLOW - Embodiments relate generally to washable pillows, particularly washable foam pillows, and methods for assembling such pillows. The washable pillow may comprise one or more cushion element and a fabric cover attached to and possibly enclosing the one or more cushion element. The pillow may also comprise a shell formed by the one or more cushion element, wherein the shell may comprise a cavity therein, and the cavity may contain a filler material. | 03-27-2014 |
Joseph E. Blazar, Minneapolis, MN US
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20150108188 | Tablet or Laptop Support Cushion - A support cushion comprising a first member comprising a first support surface and a second member coupled to the first member, the second member comprising a second support surface. The second member is configured to move relative to the first member between a first configuration and a second configuration. The first support surface of the first member and the second support surface of the second member are configured to cooperatively support a first electronic device when the second member is in the first configuration, and the first support surface of the first member is configured to support a second electronic device when the second member is in the second configuration. | 04-23-2015 |