Kern, US
Brain C. Kern, Plainfield, IN US
Patent application number | Description | Published |
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20110270785 | DECKING BEAM RACK APPARATUS AND METHOD - A method for management of conventional decking beams incorporates unique racks with special features facilitating the organization, storage, protection, and shipping of decking beams when the decking beams are not in use supporting shipments of cargo. Additional features facilitate stacking of racks when loaded with beams; and for stacking of empty racks themselves in minimal space for their storage or transportation when not in use. Identification of beams and of racks for wireless location-tracking is included. | 11-03-2011 |
Brian C. Kern, Plainfield, IN US
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20100176076 | DECKING BEAM RACK APPARATUS AND METHOD - A method for management of conventional decking beams incorporates unique racks with special features facilitating the organization, storage, protection, and shipping of decking beams when the decking beams are not in use supporting shipments of cargo. Additional features facilitate stacking of racks when loaded with beams; and for stacking of empty racks themselves in minimal space for their storage or transportation when not in use. Identification of beams and of racks for wireless location-tracking is included. | 07-15-2010 |
B. T. Kern, Lebanon, TN US
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20100300791 | MOTORCYCLE WITH A BLOWER FOR ENGINE COOLING - A motorcycle has a frame with a front and rear portion. A steering assembly is connected to the front portion, and a rear wheel is connected to the rear portion. The motorcycle includes a drive train with an air cooled engine and a transmission. The engine has a front end and a rear end, as well as a left side and a right side. The engine sides are substantially exposed, such that the engine is substantially visible when the motorcycle is viewed from the side. The motorcycle also includes a blower with an air discharge directed towards one of the front or rear ends of the engine, where the blower aid in cooling the engine. | 12-02-2010 |
20100301627 | MOTORCYCLE WITH AN AUTOMATIC AIR DEFLECTOR - A fairing upper moves with a steering assembly pivotably connected to the frame of a motorcycle. An engine guard is connected to the motorcycle frame, and a fairing lower is connected to the engine guard. A deflector is positioned adjacent to the fairing lower. The deflector includes a hinge, so the deflector has a closed hinge position and an open hinge position. A spring urges the deflector toward the closed hinge position. The spring is tensioned such that when the motorcycle reaches an open speed, wind resistance overcomes the spring tension and moves the deflector from the closed hinge position to the open hinge position. | 12-02-2010 |
Carla Kern, Ames, IA US
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20090112007 | SOLID CATALYST SYSTEM FOR BIODIESEL PRODUCTION - The invention provides efficient, inexpensive, and environmental friendly catalysts and catalyst systems. The catalysts can be used to catalyze esterification and/or transesterification reactions, for example, for the preparation of biodiesel. Kiln dust, such as cement kiln dust (CKD) or lime kiln dust (LKD) can be used to convert a variety of feedstock acids and/or esters to biodiesel in high yield under mild conditions. The CKD and LKD catalyst systems are recyclable esterification or transesterification catalysts that can be used to prepare biodiesel, such as methyl soyate, from various feedstocks, including vegetable oils and animal fats. | 04-30-2009 |
Charles Francis Kern, Marietta, OH US
Patent application number | Description | Published |
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20120205323 | SEPARATORLESS PLEATED FLUID FILTER - A fluid filter media including a first media layer, a second media layer, a filter layer disposed between the first media layer and the second media layer, and a plurality of spaced apart weld points that couple the first media layer, the filter layer, and the second media layer together, where the weld points distort the surface of the first media layer and the second media layer, the fluid filter media is folded back on itself to form a plurality of pleats, and the surface distortions permit fluid flow through the fluid filter media when adjacent surfaces of the fluid filter media touch. | 08-16-2012 |
20130045352 | NON-WOVEN FIRE BARRIER MAT - A burnthrough resistant non-woven mat is made of a glass fibers and includes a binder having a vinyl component and a strengthening component. The vinyl component may be, for example, ethylene vinyl chloride, and the strengthening component may be, for example, melamine formaldehyde. The burnthrough resistant non-woven mat may be used in conjunction with an insulation blanket, and may be especially suited to use in insulating aircraft. Methods of making the burnthrough resistant non-woven mat are discussed. | 02-21-2013 |
Charles L. Kern, Keyesport, IL US
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20090230705 | Reusable Trailer Mounted Attenuator - A reusable trailer mounted attenuator with a collapsible scissor frame assembly supported by front, intermediate and rear vertical frames. A self-adjusting shock absorber with staged metering is attached to the scissor frame assembly and controls its collapse under impact in a manner that deceleration of an impacting vehicle does not exceed permitted rates irrespective of the weight and speed of the impacting vehicle within the design range. Guides are provided to permit the scissor frame assembly to collapse without twisting and a replaceable strike plate with vertical fins concealed with a cover plate is attached to the rear vertical frame. | 09-17-2009 |
Dale Kern, Hyde Park, UT US
Patent application number | Description | Published |
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20090246152 | NARACTIN COMPOSITIONS FOR THE INHIBITION OF REACTIVE OXYGEN SPECIES - The invention relates to agents for sequestering serum aging factors, and methods for using the same. More particularly, the invention relates to agents termed herein “Naractin” to denote any one of several naturally-occurring arNOX inhibitors either present in | 10-01-2009 |
20090246153 | COSMETIC COMPOSITIONS FOR THE INHIBITION OF REACTIVE OXYGEN SPECIES - A composition and method having anti-aging properties is provided. The composition comprises an arNOX inhibitory agent present in a natural plant extract and is useful topically as a cosmetic. The symptoms of aging including lines, wrinkles, hyperpigmentation, dehydration, loss of elasticity, angioma, dryness, itching, telangietasias, actinic purpura, seborrheic keratoses and actinic keratoses. The invention may be used multiple times a day without deleterious effects. | 10-01-2009 |
Dale G. Kern, Hyde Park, UT US
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20120034613 | Apparatus and Method for Testing Relationships Between Gene Expression and Physical Appearance of Skin - The disclosure is directed to apparatus and methods for testing relationships between gene expression and physical appearance of skin and methods of assessing the efficacy of skin anti-aging agents. | 02-09-2012 |
Daniel C. Kern, Charlotte, NC US
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20120246049 | Transaction Range Comparison For Financial Investigation - Systems and methods for determining the likelihood that a group of transactions may be structured to avoid a limit or reporting requirement, such as a government reporting requirement, are disclosed. The frequency distributions of a customer's transactions for different value ranges are compared to determine whether transactions within a target range occur randomly or at an unexpected level. In another embodiment, the frequency distribution of a customer's transactions is compared to a frequency distribution created by randomly sampling a distribution of similar transactions to determine whether the customer's transactions occur randomly. | 09-27-2012 |
20120265566 | Test Portfolio Optimization System - According to one example, a test portfolio optimization system includes a test repository, an activity repository, an exception repository, and an optimization engine. The optimization engine is operable to generate a plurality of test portfolios. Each test portfolio comprises different types of tests of a plurality of tests. The optimization engine is also operable to determine a test cost for each portfolio over the period of time. The test cost for each portfolio is equal to a sum of costs for each test type within the portfolio over the period of time. The optimization engine is also operable to determine an impact per portfolio period of time. The impact per portfolio is equal to a sum of impacts per test type for each test type over the period of time. | 10-18-2012 |
20140129561 | RISK ANALYSIS USING UNSTRUCTURED DATA - Unstructured data is received from a plurality of sources to facilitate risk analysis. The unstructured data comprises a plurality of bodies of text. Each body of text from the unstructured data is deconstructed into individual terms. The individual terms from each body of text are converted into a structured form. The individual terms in the structured form are categorized according to a comparison of the structured form to another structured form. The individual terms in the structured form are quantified according to at least the categorization of the individual terms. | 05-08-2014 |
20140156340 | SYSTEM AND METHOD FOR IDENTIFYING OUTLIER RISKS - To identify outlier risks, a risk assessment is received from a first computer, and the risk assessment comprises a plurality of risks and each risk comprises a plurality of words and a plurality of attributes. A risk category associated with the risk assessment is received from a second computer, and the risk category is based on the plurality of words and the plurality of attributes and the risk category is a selected one of a high risk category and a not-high risk category. A word count is calculated for each word in each risk category. A probability score is also calculated for each word to generate a plurality of probability scores associated with the risk, and a risk score is calculated for each risk and is based on the plurality of probability scores associated with the risk. A distribution is generated that indentifies the high risk category and the not-high risk category, and the distribution identifies the risk score in the associated risk category. It is determined whether the risk associated with the risk score is an outlier for the associated risk category. | 06-05-2014 |
Darrin Lee Kern, Trout Creek, MT US
Patent application number | Description | Published |
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20120017485 | Montana long ranger rifle rest - A folding, compact, lightweight, in-the-field Hunting and Target Rifle Rest is disclosed utilizing a novel solid means of attachment to hold a rifle securely in place for maximum accuracy. The rest includes various means of attachments to solid objects including but not limited to trees, stumps, shrubs, tripods, or any other objects that may be strapped to or clamped to and fit into the rest clamp. The rest incorporates various means of adjusting the rifle when secured for repositioning its aim and comfort to the user. The rest includes attachment hardware for cameras and spotting scopes that can directly focus at the same time, on the same field of view, that the rifle is aimed towards no matter how the rifle's aim is repositioned. | 01-26-2012 |
David S. Kern, Billerica, MA US
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20100115261 | EXTENSIBLE SEAL MANAGEMENT FOR ENCRYPTED DATA - Embodiments of the present invention address deficiencies of the art in respect to seal list management in decrypting encrypted data and provide a method, system and computer program product for extensible seal management for encrypted data. In an embodiment of the invention, a method for extensible seal management for encrypted data can include identifying multiple different seal hints of different seal hint formats for different seals in a seal list associated with encrypted data and selecting from amongst the multiple different seal hints, seal hints of a recognizable seal hint format. The method also can include filtering the seals in the seal list according to the selected seal hints and attempting decryption of the filtered seals with a decryption key specified by the selected seal hints to decrypt one of the filtered seals in order to reveal a bulk key. Finally, the method can include decrypting the encrypted data with the bulk key. | 05-06-2010 |
20120151204 | Efficient Routing for Reverse Proxies and Content-based Routers - Efficient routing for a client-server session or connection is provided in an application layer of multi-layered systems interconnect stack by caching a plurality of application-specific information at an intermediary network point; using the application specific information to route messages for an application connection; and indexing the application-specific information with a key provided by the application. Optionally, a second key may be used to retrieve the application-specific information if the first key is not provided in an application connection request, where the second key is optionally opaque to the application program. The intermediary network point may be an edge of network Internet Protocol (IP) switch, and the application layer in which the routing is performed may be layer seven of the Open Systems Interconnection model. | 06-14-2012 |
David Scott Kern, Billerica, MA US
Patent application number | Description | Published |
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20100268747 | SYSTEM AND METHOD FOR NORMALIZING AND MERGING CREDENTIAL STORES - One or more data structures are received by a computing device, wherein the one or more data structures include at least one or more user credentials. The one or more user credentials are normalized by the computing device to generate a first graph. One or more nodes of the first graph and one or more nodes of at least a second graph are analyzed by the computing device, wherein analyzing includes at least identifying a logical correlation between the one or more nodes of the first graph and the one or more nodes of at least the second graph. A third graph is generated by the computing device based, at least in part, upon the analysis of the one or more nodes of the first graph and the one or more nodes of at least the second graph. An output data structure is generated by the computing device based, at least in part, upon the third graph. | 10-21-2010 |
20120151568 | Method and system for authenticating a rich client to a web or cloud application - A rich client performs single sign-on (SSO) to access a web- or cloud-based application. According to the described SSO approach, the rich client delegates to its native application server the task of obtaining a credential, such as a SAML assertion. The native server, acting on behalf of the user, obtains an assertion from a federated identity provider (IdP) that is then returned to the rich client. The rich client provides the assertion to a cloud-based proxy, which presents the assertion to an identity manager to attempt to prove that the user is entitled to access the web- or cloud-based application using the rich client. If the assertion can be verified, it is exchanged with a signed token, such as a token designed to protect against cross-site request forgery (CSRF). The rich client then accesses the web- or cloud-based application making a REST call that includes the signed token. The application, which recognizes the request as trustworthy, responds to the call with the requested data. | 06-14-2012 |
20140068743 | Secure configuration catalog of trusted identity providers - A secure database includes a catalog of information about one or more identity providers (IdPs) that are trusted by a service provider (SP) to authenticate users on the SP's behalf. The catalog securely stores one or more IdP configurations. An entry in the database stores information associated with the trusted IdP including artifacts to identify the IdP, artifacts used by the IdP for cryptographic operations, and a specification of one or more website(s) serviced by the trusted identity provider. Upon receipt by the SP of identity information representing a user that has authenticated to an IdP, information in the catalog of information is used to determine whether the IdP is trusted to authenticate the user on the service provider's behalf. The determination verifies that the SP uses the IdP and that a binding between an IdP identifier and at least one IdP cryptographic artifact is valid. | 03-06-2014 |
20150081876 | Cross-domain inactivity tracking for integrated web applications - In a cloud computing environment, a user authenticates to multiple cloud services concurrently. A master service has knowledge of or tracks the cloud service(s) to which a user is authenticated. Each cloud service may enforce its own inactivity period, and the inactivity period of at least first and second cloud services may be distinct from one another. When the master service receives an indication that the authenticated user is attempting to take an action at a first cloud service despite an activity timeout there, the master service issues a status request to at least the second cloud service to determine whether the user is still active at the second cloud service (despite its different inactivity period). If the user is still active at the second cloud service, the master service provides a response, selectively overriding (re-setting) the activity timeout at the first cloud service to permit the action. | 03-19-2015 |
Donald C. Kern, Broken Arrow, OK US
Patent application number | Description | Published |
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20100192172 | PROGRAM GUIDE SYSTEM WITH MONITORING OF ADVERTISEMENT USAGE AND USER ACTIVITIES - A program guide system is provided in which interactive television program guide advertisement usage is monitored. Advertisement usage may be monitored by monitoring when advertisements are transmitted from a television distribution facility to user television equipment. Advertisement usage information may also be monitored by monitoring when advertisements are received by the user television equipment. Advertisement usage information may also be monitored at the time at which advertisements are displayed by a program guide. Less important data may be filtered from the collected advertisement usage data. Other activities that may be monitored include the viewing activities of the user, which program guide screens are displayed, and which non-program-guide applications are used. Real-time ratings information (e.g., real-time ratings of the popularity of certain television programs, video games, or other applications) may be provided to users in real time. | 07-29-2010 |
20120240149 | SYSTEM AND METHOD FOR DISTRIBUTING AND BROADCASTING MULTIMEDIA - Multimedia distribution and broadcast systems and related processes are provided for transmitting multimedia contents and control information from a central uplink facility to a remote downlink via a satellite. The system is preferably implemented in order to generate sequences of multimedia that are broadcast from the remote downlink facility to viewers. The display arrangements of the multimedia sequences are varied and customized by each downlink facility using the control information in order to better inform and entertain viewers. | 09-20-2012 |
Douglas R. Kern, The Woodlands, TX US
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20090170748 | Plasmid mediated supplementation for treating chronically ill subjects - The present invention pertains to compositions and methods for plasmid-mediated supplementation. The compositions and methods are useful for treating anemia and other effects that are commonly associated in cancer bearing animals. Overall, the embodiments of the invention can be accomplished by delivering an effective amount of a nucleic acid expression construct that encodes a GHRH or functional biological equivalent thereof into a tissue of an animal and allowing expression of the encoded gene in the animal. For example, when such a nucleic acid sequence is delivered into the specific cells of the animal tissue specific constitutive expression is achieved. | 07-02-2009 |
20120282217 | FOOT AND MOUTH DISEASE VIRUS (FMDV) CONSENSUS PROTEINS, CODING SEQUENCES THEREFOR AND VACCINES MADE THEREFROM - Provided herein is a nucleic acid comprising consensus amino acid sequence of foot-and-mouth disease FMDV VP1-4 coat proteins of FMDV subtypes A, Asia 1, C, O, SAT1, SAT2, and SAT3 as well as plasmids and vaccines expressing the sequences. Also provided herein is methods for generating an immune response against one or more FMDV subtypes using the vaccine as described above as well as methods for deciphering between vaccinated mammals with the vaccine and those that are infected with FMDV. | 11-08-2012 |
Elizabeth C. Kern, Minneapolis, MN US
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20120222482 | Measuring Spoons and Cups - A measuring utensil includes a handle portion and a measuring portion joined to the handle portion. The handle portion includes a main body, a male component and a female component. The main body has an upper surface and a lower surface and defines at least an outer perimeter of the handle portion. The male component is located within the outer perimeter of the main body and protrudes from the upper surface of the main body to a male engaging surface. The female component is located within the outer perimeter of the main body and is recessed from the lower surface of the main body in a direction towards the upper surface of the main body. The female component extends from the lower surface of the main body to a female engaging surface. | 09-06-2012 |
20130156351 | REUSABLE BAG - A bag includes an interior pocket and an exterior pocket. The interior pocket is attached to a wall of the bag along a seam that is stitched across a width of the wall. The seam is located at a height from a bottom of the wall. The exterior pocket is attached to the bottom of the wall of the bag and has a top edge extending across the width of the wall. The top edge of the exterior pocket is located a height from the bottom of the wall. The height of the top edge of the exterior pocket is greater than the height of the seam of the interior pocket. | 06-20-2013 |
Eric M. Kern, Macomb, MI US
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20100198754 | METHOD OF PROVIDING MODULAR BATTERY PACKS FOR A HYBRID VEHICLE - A method of offering or providing batteries for a hybrid or electric vehicle allows the customer to choose a vehicle electrical battery power rating that will match their expected driving range needs. Specifically, the method includes offering different modular battery packs for an electric or hybrid electric vehicle. Each of the different modular battery packs has a different number of interconnected batteries, a different energy level, and is configured to be operable for providing propulsion power to the vehicle. At least one of the different modular battery packs is installed on the hybrid or electric vehicle. The method may include recharging and/or recycling used battery back modules. | 08-05-2010 |
Eric R. Kern, Raleigh, NC US
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20110238803 | Administration Of Virtual Machine Affinity In A Data Center - Administration of virtual machine affinity in a data center, where the data center includes a plurality of virtual machines (‘VMs’), each VM being a module of automated computing machinery installed upon a computer in the data center and characterized by a Universally Unique Identifier (‘UUID’), at least two of the VMs having an affinity requirement to be installed on separate computers, the data center further including a data center administration server operably coupled to the VMs, including communicating, by at least one of the VMs having an affinity requirement to the data center administration server, the UUIDs of the VMs having an affinity requirement; and moving by the data center administration server the VMs having an affinity requirement to separate computers in the data center. | 09-29-2011 |
20110246627 | Data Center Affinity Of Virtual Machines In A Cloud Computing Environment - Administration of virtual machine affinity among data centers in a cloud computing environment, where the cloud computing environment includes a plurality of virtual machines (‘VMs’), the VMs composed of modules of automated computing machinery installed upon cloud computers disposed within data centers, the cloud computing environment further including a cloud operating system and data center administration servers operably coupled to the VMs, including installing, by the cloud operating system on at least one VM, an indicator that at least two of the VMs have an affinity requirement to be installed upon cloud computers in separate data centers; communicating, by at least one of the VMs, the affinity requirement to at least one data center administration server; and moving by the at least one data center administration server the VMs having the affinity requirement to cloud computers in separate data centers in the cloud computing environment. | 10-06-2011 |
20110246992 | Administration Of Virtual Machine Affinity In A Cloud Computing Environment - Administration of virtual machine affinity in a cloud computing environment, where the cloud computing environment includes a plurality of virtual machines (‘VMs’), the VMs composed of modules of automated computing machinery installed upon cloud computers disposed within a data center, the cloud computing environment also including a cloud operating system and a data center administration server operably coupled to the VMs, including installing, by the cloud operating system on at least one VM, an indicator that at least two of the VMs have an affinity requirement to be installed upon separate cloud computers; communicating, by at least one of the VMs, the affinity requirement to the data center administration server; and moving by the data center administration server the VMs having the affinity requirement to separate cloud computers in the cloud computing environment. | 10-06-2011 |
Eric Richard Kern, Chapel Hill, NC US
Patent application number | Description | Published |
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20100180025 | DYNAMIC LOAD BALANCING BETWEEN CHASSIS IN A BLADE CENTER - A computer-implemented method, system and computer program product for load balancing between different blade chassis within a blade center are presented. Each blade chassis is monitored for total data traffic to and from that blade chassis. If a first blade chassis within the blade center is overworked, then a most overtaxed blade within that first blade chassis is disabled. A less utilized second blade chassis within the blade center is then identified, and a least taxed blade within the second blade chassis is assigned to take over the workload of the disabled blade from the first blade chassis. | 07-15-2010 |
20100180054 | BLADE CENTER USB LOCKING - A computer-implemented method, system and computer program product for managing USB ports on blades in a blade center are presented. A set of remotely-transmitted instructions causes a multiplexer to physically disconnect one or more selected USB ports on a blade. In one embodiment, the same one or more selected USB ports are also software-disabled by a USB software-based controller. | 07-15-2010 |
20100180161 | FORCED MANAGEMENT MODULE FAILOVER BY BMC IMPEACHMENT CONCENSUS - A computer-implemented method, system and computer program product for managing failover of Management Modules (MMs) in a blade chassis are presented. Each server blade in the blade chassis evaluates a performance of a primary MM. If a threshold number of server blades determine that the primary MM is not meeting pre-determined minimum performance standards, then a secondary MM impeaches the primary MM and takes over the management of the server blades. | 07-15-2010 |
Eric Richard Kern, Durham, NC US
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20080232398 | VIRTUAL USB COMMUNICATIONS PORT - A method and system for accessing a remote real communication port (“COM port”) from a server blade in a server blade chassis by creating a virtual COM port in the server blade. A basic input/output system (BIOS) controller monitors an internal COM port in the server blade for communication traffic. Upon detecting the communication traffic, the BIOS controller reroutes the traffic to a virtual USB COM port created by the BIOS controller chipset. The virtual USB COM port directs the communication traffic to an internal universal serial bus (USB) device in the server blade. The USB device then forwards the traffic to an Ethernet media access controller (MAC) input/output (I/O) on a sideband channel to a remote system, which passes the communication traffic to a real COM port in the remote system. | 09-25-2008 |
20080270633 | SHARED SIMULTANEOUSLY-CONNECTED DRIVES - Local drive presence is provided for local and remote drives by maintaining a plurality of uninterrupted protocol connections between a plurality of I/O controllers and a plurality of device interfaces through which peripheral bus commands are transmitted. Preferably, the I/O controllers are each housed in a separate server blade and provide each blade with access to the local and remote drives. At each of the device interfaces, rather than attaching an actual storage device, peripheral bus commands received at the device interfaces are serialized and conditionally passed or suppressed to and from the shared drive which is shared amongst the plurality of uninterrupted protocol connections. Preferably, the plurality of uninterrupted protocol connections is maintained such that the shared drives can be simultaneously shared. In one embodiment, the local drives are provided in a media tray which is shared amongst a plurality blades. | 10-30-2008 |
20080288685 | SHARED SIMULTANEOUSLY-CONNECTED DRIVES - Local drive presence is provided for local and remote drives by maintaining a plurality of uninterrupted protocol connections between a plurality of I/O controllers and a plurality of device interfaces through which peripheral bus commands are transmitted. Preferably, the I/O controllers are each housed in a separate server blade and provide each blade with access to the local and remote drives. At each of the device interfaces, rather than attaching an actual storage device, peripheral bus commands received at the device interfaces are serialized and conditionally passed or suppressed to and from the shared drive which is shared amongst the plurality of uninterrupted protocol connections. Preferably, the plurality of uninterrupted protocol connections is maintained such that the shared drives can be simultaneously shared. In one embodiment, the local drives are provided in a media tray which is shared amongst a plurality blades. | 11-20-2008 |
Frank Kern, Bellingham, WA US
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20110004748 | ELECTRICAL CIRCUITRY FOR USE IN VOLTAGE CONTROLLERS - An integrated circuit resides on a circuit board. During operation, the digital controller integrated circuit produces control signals to control a power supply for delivery of power to a load. The integrated circuit can include multiple connectivity ports, on-board memory, and mode control logic. The multiple connectivity ports such as pins, pads, etc., of the integrated circuit can be configured to provide connections between internal circuitry residing in the integrated circuit and external circuitry residing on a circuit board to which the integrated circuit is attached. The mode control logic monitors a status of one or more connectivity ports of the integrated circuit to detect when a board handler places the digital controller in a power island mode in which the integrated circuit is powered so that the board handler can access (e.g., read/write) the memory in the digital controller integrated circuit while other portions of the board are unpowered. | 01-06-2011 |
Frank William Kern, Bellingham, WA US
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20090177904 | Method, system, and apparatus for dynamic clock adjustment - A method, apparatus, article of manufacture, and system, the method including, in some embodiments, determining an impedance of a power distribution network of a load for a range of frequencies, and adjusting a functionality of the load based on a relationship between the impedance of the power distribution network for the range of frequencies and the functionality of the load. | 07-09-2009 |
Fred Robert Kern, Lexington, MA US
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20080202405 | Launch and Recovery Devices for Water Vehicles and Methods of Use - An embodiment of a launch/recovery device for both surface and underwater vehicles includes a plurality of driven wet-traction members arranged to form a low drag (e.g., water flow-through) ramp design. The wet-traction members provide traction even when wet between the water vehicle and the launch/recovery device. As a result of utilizing driven wet-traction members, the use of conventional hoists, special capture devices such as hooks and tow lines, and personnel located within the water to attach the capture devices to the water vehicle is eliminated. The wet-traction members provide both strength and flexibility to the launch/recovery device. That is, while the wet-traction members are strong enough to support the weight of the water vehicle, they are at the same time flexible enough to deflect a distance (e.g., about 6 to 15 inches) to accommodate a soft landing of the water vehicle on the ramp, while providing recovery forces and motion. | 08-28-2008 |
Gregory A. Kern, Lafayette, CO US
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20110080756 | MODIFIED ZERO VOLTAGE TRANSITION (ZVT) FULL BRIDGE CONVERTER AND PHOTOVOLTAIC (PV) ARRAY USING THE SAME - The present invention, a modified zero voltage transition (ZVT) full bridge converter, is an isolated dc/dc converter which can operate with high efficiency and high reliability in applications requiring a low input voltage and high output voltage. | 04-07-2011 |
Gregory Allen Kern, Lafayette, CO US
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20090296348 | AC PHOTOVOLTAIC MODULE AND INVERTER ASSEMBLY - An AC photovoltaic module includes a DC photovoltaic module for converting solar energy to DC electrical power, and an inverter for converting DC electrical power to AC electrical power, the inverter being adapted for connection to a frame portion of the module and being sized and configured, and provided with arrangements of electrical components thereof, to dispense heat from the inverter, whereby to prolong operational life and reliability of the inverter. | 12-03-2009 |
20120147564 | AC photovoltaic module and inverter assembly - An AC photovoltaic module includes a DC photovoltaic module for converting solar energy to DC electrical power, and an inverter for converting DC electrical power to AC electrical power, the inverter being adapted for connection to a frame portion of the module and being sized and configured, and provided with arrangements of electrical components thereof, to dispense heat from the inverter, whereby to prolong operational life and reliability of the inverter. | 06-14-2012 |
Jami R. Kern, Fort Worth, TX US
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20110274322 | DEVICES AND METHODS FOR ASSESSING CHANGES IN CORNEAL HEALTH - A computer-implemented method for use in assessing a cornea which includes selecting a principal image from among a series of layered images of the cornea. The computer-implemented method further includes detecting a plurality of corneal structures in the principal image and providing a quantitative analysis of the plurality of corneal structures. | 11-10-2011 |
Jeffrey Kern, Louisville, KY US
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20090235674 | DEMAND DRIVEN ICE MODE SOFTWARE - This disclosure is related to software that responds to consumer usage patterns in order to create more ice. The developed software monitors ice dispenses rather they are crushed or cubed. When a threshold of the number of dispenses within the preset time period has been met, the freezer enters a high demand mode. During high demand mode, the freezer is commanded to run at a colder temperature for a preset period of time. The method described in this disclosure includes setting a threshold for the number of dispenses within a time interval and detecting the number of dispenses that are related to a trigger's activation. The method continues with sending a signal when the number of dispenses surpasses the threshold within the time interval and taking a corrective action that increases the production of ice when the signal is received. | 09-24-2009 |
Jeffrey A. Kern, Louisville, KY US
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20120023990 | HYBRID ELECTRIC WATER HEATER WITH EXTERNAL DISCHARGE DUCTING - A duct adapter system directs air flow relative to a hybrid water heater. The duct adapter system includes a collar adapted to surround a vent of a hybrid water shroud. The collar couples to standard duct pipe to extend ductwork to a heat pump portion of the hybrid water heater. A boost fan may be included in the system for boosting air flow to or from a remote location. The duct adapter system is adapted to deliver a warm air supply to the heat pump from the remote location, or deliver the cool discharge air from the heat pump water heater to a remote location. | 02-02-2012 |
Jeffrey Alan Kern, Louisville, KY US
Patent application number | Description | Published |
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20100206869 | HEAT PUMP WATER HEATER CONTROL - Systems and methods for controlling a heat pump water heater (HPWH) are disclosed. The systems include an interface for accepting a user input and configured to indicate a mode of operation, and indicate at least one error condition when an error condition exists. The systems are operative to diagnose various failure conditions and as advise a user that maintenance may be needed and to adjust operation for varying environmental or other external conditions. | 08-19-2010 |
20100209084 | RESIDENTIAL HEAT PUMP WATER HEATER - A heat pump water heater and systems and methods for its control are disclosed. The systems are configured to heat water within a water storage tank of a heat pump water heater wherein a controller within the system is operatively connected to a plurality of heat sources including at least one electric heating element and a heat pump and sensors in order to selectively energize one of the plurality of heat sources. The controller is configure to process data representative of the temperature of water within the tank near the top of the water storage tank, and rate of water flowing out of the water storage tank, in order to automatically selectively energize the heat sources. The selection of heat sources by the controller is determined by a mode of operation selected by the user and the data processed by the controller in view of the selected mode of operation. | 08-19-2010 |
20120145095 | RESIDENTIAL HEAT PUMP WATER HEATER - A heat pump water heater and systems and methods for its control. The systems are configured to heat water within a water storage tank of a heat pump water heater wherein a controller within the system is operatively connected to a plurality of heat sources including at least one electric heating element and a heat pump and sensors in order to selectively energize one of the plurality of heat sources. The controller is configure to process data representative of the temperature of water within the tank near the top of the water storage tank, and rate of water flowing out of the water storage tank, in order to automatically selectively energize the heat sources. The selection of heat sources by the controller is determined by a mode of operation selected by the user and the data processed by the controller in view of the selected mode of operation. | 06-14-2012 |
Jeffrey Curtis Kern, Gilbertsville, PA US
Patent application number | Description | Published |
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20090325916 | 5-ARYL INDAN-1-ONE AND ANALOGS USEFUL AS PROGESTERONE RECEPTOR MODULATORS - Compounds of formula I or II and pharmaceutical compositions and kits containing these compounds are provided. Also provided are methods of inducing contraception, providing hormone replacement therapy, treating cycle-related symptoms, or treating or preventing benign or malignant neoplastic disease using the compounds of formula I, formula II, or formula III. | 12-31-2009 |
20100267697 | ION CHANNEL MODULATORS - The present teachings provide compounds of Formula (I) | 10-21-2010 |
John L. Kern, Marysville, OH US
Patent application number | Description | Published |
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20110095459 | HYDRAULIC ENGINE MOUNT - A hydraulic engine mount assembly includes a support bracket defining a passageway that communicates between a pair of fluid chambers formed in an elastomeric body. According to one embodiment, the mount includes first and second connection devices for respectively connecting the engine mount to first and second connection surfaces. | 04-28-2011 |
John M. Kern US
Patent application number | Description | Published |
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20100244446 | GAS TURBINE ENGINE ASSEMBLY INCLUDING DUAL SIDED/ DUAL SHAFT ELECTRICAL MACHINE - A gas turbine engine assembly includes an electromagnetic machine for extracting power from the turbine engine. The electromagnetic machine includes an outer rotor and an inner rotor rotatably supported adjacent to a stator disposed between the inner and outer rotors. The stator has an inner set of windings disposed on an inner surface adjacent to the inner rotor, and an outer set of windings on an outer surface of the stator adjacent to the outer rotor. The inner stator windings form a set of multiple-phase windings, and the outer stator windings form a set of multiple-phase windings. | 09-30-2010 |
Jonathan Fred Kern, Seattle, WA US
Patent application number | Description | Published |
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20110265027 | COLLAPSIBLE TABBED USER INTERFACE - A tab-based collapsible user interface includes selectable user interface tabs, a ribbon area, and an editing surface. When a browse tab is selected, the ribbon area displays information and does not include any user interface controls for performing commands. When the browse tab is selected, a vertical scroll bar is displayed adjacent to the ribbon area and the editing surface. When the vertical scroll bar is used, the ribbon area and the editing surface are both scrolled. When a page tab or a contextual tab is selected, the ribbon area displays user interface controls for performing commands. When a page tab or a contextual tab is selected, a vertical scroll bar is displayed adjacent to the editing surface but not adjacent to the ribbon area. When the vertical scroll bar is used, the contents of the editing surface are scrolled but the ribbon area is not scrolled. | 10-27-2011 |
20110276906 | NAVIGATIONAL INFORMATION USER INTERFACE - A navigational information display panel is provided for presenting information associated with a location and relationship of a particular web page in context of hierarchical nodes above the web page. The panel may be displayed at a fixed or movable location upon activation of a navigational information control on a browsing application user interface. The panel may include various display structures representing the web page's contextual location in an effective manner along with navigational links for quick navigation to nodes above the web page (and/or at the same level). | 11-10-2011 |
20110283215 | INTEGRATED USER INTERFACE CONTROLS FOR WEB DIALOGS - A web application dialog user interface is provided for presenting users with controls for viewing, editing, and otherwise managing content through the web application. Consistency in style and order of control elements in the user interface with control elements of a standard application user interface, launching of the dialog without a page refresh, and maintenance of task continuity provide users a seamless experience in managing their documents through the web application without loss of context. | 11-17-2011 |
20110321029 | UPGRADE MANAGEMENT OF APPLICATION COMPONENTS - Architecture that enables separation of a user interface (UI) upgrade from the content and application logic upgrade. Administrators can upgrade to take advantage of new infrastructure features, and independently schedule the UI upgrade, for example, to accommodate customization work or to ensure user training. Furthermore, administrators can now allow users to choose when to switch to the new UI. More specifically, the architecture facilitates the separation of a UI upgrade from content and application logic upgrade, the ability to control the UI upgrade at multiple levels of precision, the ability for application logic and UI components to change behaviors based on the UI version of the context, and the ability to “preview” the updated UI before permanently switching to it. Additionally, UI components can be filtered to only appear in the appropriate UI version, and the site's UI version can be compared to versions that a component is compatible with. | 12-29-2011 |
Jonathan T. Kern, Souderton, PA US
Patent application number | Description | Published |
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20100029012 | Method for identifying modulators of the NRF2-KEAP1-AREP pathway - A method for identifying modulators of the Keap1-NrG-ARE pathway is described. In particular, an assay is described that identifies molecules that inhibit the binding of a labeled Nrf2 peptide with the kelch domain of the Keap1 protein. Molecules that inhibit the binding are activators of the Keap 1-Nrf2-ARE pathway. Activation of the Keap 1-Nrf2-ARE pathway may result in an increased accumulation of Nrf2 and the subsequent induction of protective enzymes, for example, the phase 2 detoxification enzymes. Activators of the Keap1-NrG-ARE pathway are useful for combating oxidative stress-related disorders, such as those associated with cancer, emphysema, Huntington's disease, light-induced retinal damage, and stroke. | 02-04-2010 |
20130296317 | LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY - Disclosed are compounds of Formula (I): and the pharmaceutically acceptable salts thereof, wherein “A” is S—; —SO—, —SO | 11-07-2013 |
20130338106 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY - Disclosed are compounds of Formula I: and the pharmaceutically acceptable salts thereof, wherein “A” is S—; —SO—, —SO | 12-19-2013 |
Karl C. Kern, Plainfield, IN US
Patent application number | Description | Published |
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20100176076 | DECKING BEAM RACK APPARATUS AND METHOD - A method for management of conventional decking beams incorporates unique racks with special features facilitating the organization, storage, protection, and shipping of decking beams when the decking beams are not in use supporting shipments of cargo. Additional features facilitate stacking of racks when loaded with beams; and for stacking of empty racks themselves in minimal space for their storage or transportation when not in use. Identification of beams and of racks for wireless location-tracking is included. | 07-15-2010 |
20110270785 | DECKING BEAM RACK APPARATUS AND METHOD - A method for management of conventional decking beams incorporates unique racks with special features facilitating the organization, storage, protection, and shipping of decking beams when the decking beams are not in use supporting shipments of cargo. Additional features facilitate stacking of racks when loaded with beams; and for stacking of empty racks themselves in minimal space for their storage or transportation when not in use. Identification of beams and of racks for wireless location-tracking is included. | 11-03-2011 |
K. Jon Kern, Franktown, CO US
Patent application number | Description | Published |
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20110119120 | Loyalty reward program for reducing the balance of a loan obligation - A method and apparatus for reducing the balance of a consumer or educational loan obligation using a loyalty reward program is disclosed. Loan obligors can reduce the balances of their loan obligations by purchasing consumer goods and services that they would normally purchase. The method essentially comprises the steps of (a) establishing a site on a global computer network; (b) recognizing at least certain users of the site; (c) directing the recognized users to merchants; (d) enabling accumulation of loyalty points by the recognized users based upon purchases from the merchants; (e) monitoring the purchases by the recognized users from the merchants; (f) tracking the accumulated loyalty points; and (g) permitting selective redemption of the accumulated loyalty points. Users of the site are recognized by requiring them to provide initial registration information. Accumulated loyalty points may be categorized with a status of “pending” or a status of “earned.” Selective redemption of the accumulated loyalty points includes selective application of earned loyalty points to a loan of a recognized user to permit repayment of the loan, or selective transfer of earned loyalty points from one recognized user to another recognized user. Information about accumulated, redeemed, and transferred loyalty points may be displaying to a recognized user. | 05-19-2011 |
Kristopher T. Kern, Strongsville, OH US
Patent application number | Description | Published |
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20120095787 | INTELLIGENT ROUTER FOR MEDICAL PAYMENTS - One or more servers ( | 04-19-2012 |
20140095195 | INTELLIGENT ROUTER FOR MEDICAL PAYMENTS - One or more servers ( | 04-03-2014 |
Laura Kern, Seattle, WA US
Patent application number | Description | Published |
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20110320443 | Navigation to Popular Search Results - Systems, methods, and computer media for enhancing search results, as well as user interfaces for performing search queries and navigating search results, are provided. A search query is received from a user. A plurality of web pages relevant to the search query are identified. At least one of the relevant web pages is identified as popular. A search result page is generated including a search result listing and a search result page header. The search result page header includes a link to the popular web page to provide the user with a quick and easy way to select a popular web page relevant to the user's search query. | 12-29-2011 |
Laura J. Kern, Seattle, WA US
Ludwig Kern, Arnold, MD US
Patent application number | Description | Published |
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20130016431 | CONCENTRATING AND SPECTRUM SPLITTING OPTICAL DEVICE FOR SOLAR ENERGY APPLICATIONS - An optical device capable of concentrating and spectrum splitting electromagnetic radiation for solar energy conversion systems. Two interfaces of the optical device, designed by ray tracing methods, focus the electromagnetic radiation by refraction and chromatic dispersion, such that focal areas of different wavelengths, relative to one another, are not parallel to electromagnetic radiation incident upon the optical device. Energy conversion devices, such as solar photovoltaic cells, may be placed at or near the focal areas to efficiently convert radiation of different wavelengths to other forms of energy. Interfaces may be flat or curved and may be composed of multiple discontinuous surfaces on one or both interfaces in one or two axes. Interfaces composed of multiple discontinuities may be designed such that there is no shading of electromagnetic radiation of selected wavelengths. The optical device may be composed of one material or multiple materials with different Abbe numbers. | 01-17-2013 |
Lynn Kern, Woodway, WA US
Patent application number | Description | Published |
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20090172926 | DOG LEASH WITH INTEGRATED WASTE CARRYING ATTACHMENT - This invention provides the pet owner with a leash that has a readily accessible storage area for empty excrement collecting bags. Because of its simple design, any additional bulk added to the leash because of this invention is negligible. Consequently, the leash can be folded and stored as usual; the pet owner need not think of or care for additional gadgets attached to the leash. | 07-09-2009 |
Mary Rossick Kern, Castle Rock, CO US
Patent application number | Description | Published |
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20080208705 | PERSONALIZED SHOPPING ASSISTANT - Methods and systems of providing purchasing suggestions to a shopper are disclosed. Data are maintained representing one or more profiles of individuals. Each such profile includes a plurality of fields descriptive of qualities of one of the individuals. A request is received over a public network from the shopper to provide a purchasing suggestion for a recipient. A level of correlation is evaluated between aspects of each of a plurality of products with the qualities of the recipient according to the profile of the recipient. A list of products having the level of correlation exceed a defined threshold value is generated. The list is provided to the shopper. | 08-28-2008 |
Matthew Kern, Bend, OR US
Patent application number | Description | Published |
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20100162229 | FRAMEWORK VERSIONING - Various embodiments are directed to framework versioning for a mobile computing device. The described embodiments may include a web browser, a plurality of application frameworks, one or more applications compatible with one or more of the plurality of application frameworks, and a loader module operative to select and load one of the plurality of application frameworks into the web browser for each of the one or more applications based on an identifier in each of the one or more applications. Other embodiments are described and claimed. | 06-24-2010 |
Melissa R. Kern, Mt. Airy, NC US
Patent application number | Description | Published |
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20120145321 | CURABLE PROTECTANT FOR ELECTRONIC ASSEMBLIES - Latent thermal initiators and protectant compositions that remain shelf stable at elevated temperatures, yet readily cure during a solder bump reflow process or other high temperature processing. The thermal initiators comprise thermally labile cation-anion pairs where the blocked cation prevents cure at low temperatures, and the unblocked cation initiates cure at high temperatures. Also provided is a method of making a preferred initiator comprising the cation [N-(4-methylbenzyl)-N,N-dimethylanalinium] and the anion [N(SO | 06-14-2012 |
Michael Kern, Minneapolis, MN US
Patent application number | Description | Published |
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20080275401 | Catheter anchor and system/method regarding same - An anchor for use in an anchor system and method for securing a catheter to tissue includes a flexible body portion that defines one or more openings through which a catheter is positioned when secured to the tissue. For example, the one or more openings may be a channel through the anchor having a diameter that is less than the outer diameter of the catheter. | 11-06-2008 |
Michael Kern, South Beloit, IL US
Patent application number | Description | Published |
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20100083721 | DECOILER FOR WIRE AND ROD - A decoiler for delivery of wire or rod feed stock to a downstream production machine from a pre-formed coil. The decoiler includes an extended length rotatable mandrel adapted to extend along the interior of the coil such that the mandrel supports loops of the coil in hanging and slidable relation along the mandrel. At least a first feed head is disposed adjacent to the proximal end of the mandrel. The first feed head is adapted to feed the wire or rod feed stock from a rear loop of the coil outwardly in a curved path to form a spiral feed loop having a diameter greater than the coil. A variable height guide element is disposed at a position below the first feed head. The variable height guide element engages and follows an interior of the spiral feed loop to change height with a change in diameter of the spiral feed loop and to provide an output signal for speed control of the first feed head to maintain the diameter of the spiral feed loop within predefined limits. | 04-08-2010 |
Michael J. Kern, St. Louis Park, MN US
Patent application number | Description | Published |
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20090216202 | DELIVERY NEEDLE APPARATUS WITH SLEEVE - A delivery needle apparatus in which a sleeve is fitted over an exterior surface of a delivery needle and methods of manufacturing the same. An elongate medical device may be delivered through the interior of the delivery needle and out of an opening in the distal end of the delivery needle (i.e., the delivery opening). The sleeve may cover a proximal portion of the delivery opening and may align an elongate medical device during insertion and/or withdrawal through the delivery opening. | 08-27-2009 |
20110040257 | ANCHOR DEPLOYMENT APPARATUS - An anchor deployment apparatus for deploying an anchor about a therapy delivery element includes an anchor receiving element having an elongate member having a distal opening and a lumen extending proximally in the elongate member from the distal opening. The lumen of the elongate member is configured to slidably receive at least a portion of a therapy delivery element. The anchor deployment tool further includes an anchor engagement element having (i) a body forming a channel in which the elongate member of the anchor receiving element is axially movable, and (ii) an engagement feature forming at least a part of the channel. The engagement feature is configured to engage the anchor when the anchor is disposed about the elongate member and the elongate member is moved distally relative to the engagement element, and to cause the anchor to move distally along the elongate member when the feature is engaged with the anchor and the elongate member is moved distally relative to the engagement element. The anchor deployment tool also includes an alignment element secured relative to the elongate member and configured to secure the elongate member relative to the body of the anchor engagement element to restrict movement of the elongate member orthogonal to the axis of the channel. The anchor receiving element and the alignment element may be formed from the same or different parts. | 02-17-2011 |
20110245887 | Medical Leads and Related Systems that Include Coiled Filars with Longitudinally Straight Ends - Medical leads included coiled filars that have longitudinally straight ends. The coiled filars may be coiled at a constant pitch until reaching the point where the filars become longitudinally straight. The coiled filars may reside within a central lumen of the lead body, while the longitudinally straight portions may reside in a region where electrical connectors are present and where filar passageways provide a pathway for the filars to exit the central lumen and bond with the electrical connectors. The coiled filars may be created with longitudinally straight ends using a body that includes longitudinally straight holes that receive the filars and maintain the longitudinally straight configuration while the remaining portion of the filars is being coiled. | 10-06-2011 |
20110257659 | STRAIN RELIEF APPARATUS FOR USE WITH IMPLANTABLE MEDICAL LEAD - An extensible implantable medical device includes a body defining a lumen extending through the body. The lumen is configured to receive at least a portion of an implantable medical lead. The body includes a non-rectilinearly shaped portion. The non-rectilinearly shaped portion has a first shape spanning a first distance in a relaxed state. The non-rectilinearly shaped portion has a second, more rectilinear, shape spanning a second distance when subjected to a stretching force. The second distance is greater than the first distance. The non-rectilinearly shaped portion returns to the relaxed first shape upon release of the stretching force and is configured to assume the first shape when the lead is inserted into the lumen and no load is placed on the lead or the shaped body portion. | 10-20-2011 |
20120035696 | TERMINATION OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD - A shield located within an implantable medical lead may be terminated in various ways. The shield may be terminated by butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. For lap joints, a portion of an outer insulation layer may be removed and a replacement outer insulation layer is positioned in place of the removed outer insulation layer, where the replacement layer extends beyond an inner insulation layer and the shield. The replacement layer may also lap onto a portion of the insulation extension. Barbs may be located between the replacement layer and the inner insulation layer or the insulation extension. The shield wires have ends at the termination point that may be folded over individually or may be capped with a ring located within one of the insulation layers of the jacket. | 02-09-2012 |
20120041528 | TERMINATION OF A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD - A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector. | 02-16-2012 |
20120041529 | ESTABLISHING CONTINUITY BETWEEN A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD AND A SHIELD WITHIN AN IMPLANTABLE LEAD EXTENSION - Implantable medical leads and implantable lead extensions include a shield. The implantable medical lead is coupled to the implantable lead extension. Stimulation electrodes of the implantable medical lead contact stimulation connectors within a housing of the implantable extension to establish a conductive pathway for stimulation signals from filars of the implantable extension to filars of the implantable medical lead. Continuity is established between the shield of the implantable medical lead and the implantable extension by providing a radio frequency conductive pathway within the housing. The radio frequency conductive pathway extends from a shield of the implantable extension to a shield connector that contacts a shield electrode of the implantable medical lead. The radio frequency conductive pathway may have various forms such as a jumper wire or an extension of the shield within the implantable extension. | 02-16-2012 |
20120071958 | Medical Leads and Related Systems that Include a Lumen Body That Is Joined to a Lead Body and That Has Multiple Filar Lumens - Medical leads include a lumen body at an end of the lead, and the lumen body includes multiple filar lumens. The lumen body is joined to a lead body, and electrical connectors are longitudinally spaced along the lumen body. Filars within the filar lumens are directed through filar passageways within the lumen body to attach to the electrical connectors on the lumen body. The filar passageways may be aligned with the filar lumens, and slots within the electrical connectors may be aligned with the filar passageways to facilitate assembly. The lumen body may provide additional stiffness to the end of the lead where the lumen body is located to facilitate lead insertion into the medical device. The filar lumens of the lumen body may have a longitudinally straight configuration so that the portions of filars within the filar lumens are held in a longitudinally straight configuration. | 03-22-2012 |
20120130461 | RADIOPAQUE MARKERS FOR IMPLANTABLE MEDICAL LEADS, DEVICES, AND SYSTEMS - Radiopaque markers represent that a lead is suitable for a particular medical procedure such as a magnetic resonance image scan and are added to the lead or related device. The markers may be added after implantation of the lead in various ways including suturing, gluing, crimping, or clamping a radiopaque tag to the lead or to the device. The markers may be added by placing a radiopaque coil about the lead, and the radiopaque coil may radially contract against the lead to obtain a fixed position. The markers may be added by placing a polymer structure onto the lead where the polymer structure includes a radiopaque marker within it. The polymer structure may include a cylindrical aperture that contracts against the lead to fix the position of the structure. The polymer structure may form a lead anchor that includes suture wings that can be sutured to the lead. | 05-24-2012 |
20120157936 | DELIVERY NEEDLE APPARATUS WITH SLEEVE - A delivery needle apparatus in which a sleeve is fitted over an exterior surface of a delivery needle and methods of manufacturing the same. An elongate medical device may be delivered through the interior of the delivery needle and out of an opening in the distal end of the delivery needle (i.e., the delivery opening). The sleeve may cover a proximal portion of the delivery opening and may align an elongate medical device during insertion and/or withdrawal through the delivery opening. | 06-21-2012 |
20120197264 | TOOLS AND METHODS FOR REMOVING ANCHORS FROM MEDICAL LEADS - Tools and methods for removing anchors from medical leads involve a guide portion and a blade. The lead is inserted within a lead passageway of the guide portion of the tool and the tool is moved along so that the blade contacts the anchor and cuts a slit in the anchor as the tool. Once the blade has cut the slit through the entire anchor, the anchor comes free of the lead and the tool can be removed. The tool may include a manner of opening and closing the guide portion so as to provide access to the lead when open and to contain the lead when closed. Opening the guide portion allows the lead to be inserted or removed by laterally moving the lead into or out of the lead passageway such that the tool may be installed or removed at any available point along the lead. | 08-02-2012 |
20120197367 | ANCHORS INCLUDING RIGID BODIES DEFINING FULL LENGTH SLOTS FOR USE WITH IMPLANTABLE MEDICAL LEADS - Anchors for use with implantable medical leads include an elastic body containing one or more rigid bodies that have longitudinal free edges. The longitudinal free edges run from end to end to define full length slots. Partial length slots may also be included within the one or more rigid bodies. The full length and partial length slots allow for deflection of the rigid bodies against the body of an implantable medical lead to hold the anchor in place on the lead. The full length slots allow a blade to pass through and cut a slit in the elastic body which allows the anchor to be removed from the lead. | 08-02-2012 |
20130296990 | Medical Leads and Related Systems that Include a Lumen Body that is Joined to a Lead Body and that has Multiple Filar Lumens - Medical leads include a lumen body at an end of the lead, and the lumen body includes multiple filar lumens. The lumen body is joined to a lead body, and electrical connectors are longitudinally spaced along the lumen body. Filars within the filar lumens are directed through filar passageways within the lumen body to attach to the electrical connectors on the lumen body. The filar passageways may be aligned with the filar lumens, and slots within the electrical connectors may be aligned with the filar passageways to facilitate assembly. The lumen body may provide additional stiffness to the end of the lead where the lumen body is located to facilitate lead insertion into the medical device. The filar lumens of the lumen body may have a longitudinally straight configuration so that the portions of filars within the filar lumens are held in a longitudinally straight configuration. | 11-07-2013 |
20140107750 | Medical Leads and Related Systems that Include a Lumen Body that is Joined to a Lead Body and that has Multiple Filar Lumens - Medical leads include a lumen body at an end of the lead, and the lumen body includes multiple filar lumens. The lumen body is joined to a lead body, and electrical connectors are longitudinally spaced along the lumen body. Filars within the filar lumens are directed through filar passageways within the lumen body to attach to the electrical connectors on the lumen body. The filar passageways may be aligned with the filar lumens, and slots within the electrical connectors may be aligned with the filar passageways to facilitate assembly. The lumen body may provide additional stiffness to the end of the lead where the lumen body is located to facilitate lead insertion into the medical device. The filar lumens of the lumen body may have a longitudinally straight configuration so that the portions of filars within the filar lumens are held in a longitudinally straight configuration. | 04-17-2014 |
20140180215 | ANCHOR DEPLOYMENT APPARATUS - An anchor deployment apparatus for deploying an anchor about a therapy delivery element includes an anchor receiving element having an elongate member having a distal opening and a lumen extending proximally in the elongate member from the distal opening. The lumen of the elongate member is configured to slidably receive at least a portion of a therapy delivery element. The anchor deployment tool further includes an anchor engagement element having (i) a body forming a channel in which the elongate member of the anchor receiving element is axially movable, and (ii) an engagement feature forming at least a part of the channel. The engagement feature is configured to engage the anchor when the anchor is disposed about the elongate member and the elongate member is moved distally relative to the engagement element, and to cause the anchor to move distally along the elongate member when the feature is engaged with the anchor and the elongate member is moved distally relative to the engagement element. The anchor deployment tool also includes an alignment element secured relative to the elongate member and configured to secure the elongate member relative to the body of the anchor engagement element to restrict movement of the elongate member orthogonal to the axis of the channel. The anchor receiving element and the alignment element may be formed from the same or different parts. | 06-26-2014 |
20140257318 | Anchor Deployment for Implantable Medical Devices - A tool for deploying an anchor sleeve onto an implantable device includes handle and base members, which may be fitted together by an operator. The operator may select the handle member from a plurality thereof included in a kit; and the base member, also included in the kit, includes a rail segment with which a gripping portion of the selected handle member may be engaged, for example, via guidance from a marked portion of the base member. Once engaged, a deployment tip of the base member is located to move a mounted anchor sleeve from a tubular member of the handle member and onto a body of the device. The tubular member of some tools has a laterally offset distal end portion, on which the corresponding anchor sleeve is mounted; thus, kits including this type of handle member, may include a converter for the base member to facilitate engagement therewith. | 09-11-2014 |
20140324064 | INTRODUCTION AND ANCHORING TOOL FOR AN IMPLANTABLE MEDICAL DEVICE ELEMENT - The invention pertains to an apparatus comprising a needle configured to define a path through tissue of a patient, tubing configured to slidably receive the needle via a proximal opening, an anchor configured to slidably receive at least a portion of the tubing, and an anchor deployment member comprising a body and an anchor engagement member. Such an apparatus may be used to introduce and anchor an implantable medical device element within a patient. | 10-30-2014 |
Michael J. Kern, Mount Pleasant, SC US
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20110033516 | METHODS AND COMPOSITIONS FOR BONE HEALING BY PERIOSTIN - The present invention provides methods and compositions for increasing bone production and/or decreasing bone fracture healing time in a subject, by administering an effective amount of periostin and/or active peptides and/or fragments thereof. | 02-10-2011 |
Nicole Kern, Cleveland Heights, OH US
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20100268137 | ORTHOTIC BRACE - An orthotic brace ( | 10-21-2010 |
Ralf Kern US
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20080220711 | Ventilation device - The device has an air nozzle ( | 09-11-2008 |
Randall Kern, Seattle, WA US
Patent application number | Description | Published |
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20120166598 | DISTRIBUTED NETWORK COORDINATE SYSTEM - This document relates to a distributed network coordinate system. One implementation provides computer-readable storage media including instructions that may cause a processor to perform certain acts. For example, the acts may include storing an initial network location of a first device in a network. The network may include the first device and a second device. The acts may also include monitoring one or more network performance metrics related to existing application communications with the second device, and determining an updated network location of the first device, based on the initial network location and the network performance metrics. Aspects of network health can be derived from monitoring changes in the network locations of various devices within the coordinate system. | 06-28-2012 |
20140337524 | DISTRIBUTED NETWORK COORDINATE SYSTEM - This document relates to a distributed network coordinate system. One implementation provides computer-readable storage media including instructions that may cause a processor to perform certain acts. For example, the acts may include storing an initial network location of a first device in a network. The network may include the first device and a second device. The acts may also include monitoring one or more network performance metrics related to existing application communications with the second device, and determining an updated network location of the first device, based on the initial network location and the network performance metrics. Aspects of network health can be derived from monitoring changes in the network locations of various devices within the coordinate system. | 11-13-2014 |
Randall Kern, Redmond, WA US
Patent application number | Description | Published |
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20110270908 | TRANSPARENT MIGRATION OF ENDPOINT - Architecture that facilitates the capture of connection state of a connection established between a client and an intermediate server and forwards the state to one or more target servers. A software component at the target server (as well as the intermediate server) uses this connection state to reply back to the client directly, thereby bypassing the intermediate server. All packets from the client related to the request are received at the intermediate server and then forwarded to the target server. The migration can be accomplished without any change in the client operating system and client applications, without assistance from a gateway device such as a load balancer or the network, without duplication of all packets between the multiple servers, and without changes to the transport layer stack of the intermediate and target servers. | 11-03-2011 |
Randall F. Kern, Seattle, WA US
Patent application number | Description | Published |
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20090198746 | GENERATING ANONYMOUS LOG ENTRIES - Assigning session identifications to log entries and generating anonymous log entries are provided. In order to balance users' privacy concerns with the need for analysis of the log entries to provide high quality search results, non-user-specific data fields, such as a user's location (e.g., city, state, and latitude/longitude) and connection speed, are inserted into the log entries, and user-specific data fields, such as the IP address and cookie identifications, are deleted from the log entries. In addition or alternatively, prior to anonymization of the log entries, session identifications are assigned to identified groups of log entries. The groups are identified based on factors such as the user's identification, the IP address, the time of search, and differences between the search terms used in the search queries. | 08-06-2009 |
Randall F. Kern, Bellevue, WA US
Patent application number | Description | Published |
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20110167043 | GENERATING ANONYMOUS LOG ENTRIES - Assigning session identifications to log entries and generating anonymous log entries are provided. In order to balance users' privacy concerns with the need for analysis of the log entries to provide high quality search results, non-user-specific data fields, such as a user's location (e.g., city, state, and latitude/longitude) and connection speed, are inserted into the log entries, and user-specific data fields, such as the IP address and cookie identifications, are deleted from the log entries. In addition or alternatively, prior to anonymization of the log entries, session identifications are assigned to identified groups of log entries. The groups are identified based on factors such as the user's identification, the IP address, the time of search, and differences between the search terms used in the search queries. | 07-07-2011 |
Randall Friend Kern, Seattle, WA US
Patent application number | Description | Published |
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20100299349 | Reducing Latency in Returning Online Search Results - An embodiment of the invention is directed to reducing search-response latency. The closest intermediate server can be located between a client computing device and a search engine. A search query is sent to the intermediate server in a first packet of a transport protocol handshake. A plurality of packets are received from the intermediate server. The plurality of packets are used to open a window associated with a transport protocol. A response related to the search query is received by the client. | 11-25-2010 |
20130346465 | APPLICATION ENHANCEMENT USING EDGE DATA CENTER - A management service that receives requests for the cloud computing environment to host applications, and improves performance of the application using an edge server. In response to the original request, the management service allocates the application to run on an origin data center, evaluates the application by evaluating at least one of the application properties designated by an application code author or provider, or the application performance, and uses an edge server to improve performance of the application in response to evaluating the application. For instance, a portion of application code may be offloaded to run on the edge data center, a portion of application data may be cached at the edge data center, or the edge server may add functionality to the application. | 12-26-2013 |
Randy Kern, Redmond, WA US
Patent application number | Description | Published |
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20100302940 | LOAD BALANCING ACROSS LAYER-2 DOMAINS - The present application relates to network configurations and specifically to scalable load balancing network configurations. One implementation includes an external client coupled to a scalable load balancing system. The scalable load balancing system includes a load balancing layer that is configured to encapsulate individual incoming packets of a packet flow from the external client. The load balancing layer is further configured to route the incoming packets to target devices on the system. The target devices can span multiple IP subnets. The incoming packets can pass through one or more load balancers of the load balancing layer before reaching individual target devices. Individual target devices can be configured to route at least some outgoing packets of the packet flow to the external client without passing through any of the one or more load balancers. | 12-02-2010 |
Richard M. Kern, Highland Village, TX US
Patent application number | Description | Published |
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20110315507 | Extendable Conveyor with Multifunctional User Interface Section - An extendable boom loader and system. The extendable boom loader includes a distal boom element and a package tray. The boom element includes a package stop that moves to a first position blocking passage of packages and a second position allowing passage of packages, and a securing mechanism that holds the package stop in the first position. The package tray moves to first and second positions, respectively retracted within and extending from the boom element. The tray includes a tray package stop apparatus that prevents packages from sliding off a distal end of the tray. The distal boom element further includes a drawer unit that moves to first and second positions, respectively retracted within and extending from the tray. The drawer unit is configured to pivot down, while in its second position, to reach a floor of a container being loaded using the extendable boom loader. | 12-29-2011 |
Robert Kern, Indianapolis, IN US
Patent application number | Description | Published |
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20110139136 | TECHNIQUES FOR ENHANCING AFTERTREATMENT REGENERATION CAPABILITY - A system is provided for enhancing aftertreatment regeneration capability. The system includes an internal combustion engine producing an exhaust gas stream and an aftertreatment component that treats the exhaust gas stream, where the aftertreatment component includes a desired inlet exhaust gas temperature. The system includes an exhaust gas pressure device that modulates an exhaust pressure value, and a fuel injection system that provides a post-injection event. The system includes a controller that provides an exhaust pressure command and a fuel injection command in response to determining that a temperature of the exhaust gas stream is lower than the desired inlet exhaust gas temperature. The exhaust gas pressure device is responsive to the exhaust pressure command and the fuel injection system is responsive to the fuel injection command. | 06-16-2011 |
20110146270 | TECHNIQUES FOR OPTIMIZING ENGINE OPERATIONS DURING AFTERTREATMENT REGENERATION - A system is described for producing an elevated exhaust temperature and reduced NO | 06-23-2011 |
Robert Kern, Columbus, IN US
Patent application number | Description | Published |
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20110146240 | APPARATUS, SYSTEM, AND METHOD FOR MITIGATING DIESEL EXHAUST FLUID DEPOSITS AND ASSOCIATED CONDITIONS - According to one embodiment, described herein is an apparatus for mitigating on-board diagnostic (OBD) faults generated by an OBD system of an internal combustion engine (ICE) system having a selective catalytic reduction system with a diesel exhaust fluid (DEF) decomposition tube. The apparatus includes a fault mitigation module that is configured to monitor at least one OBD signal of the OBD system and issue a request for regenerating the DEF decomposition tube when a value of the at least one OBD signal reaches a predetermined regeneration threshold corresponding with the at least one OBD signal. The regeneration threshold is reachable prior to an OBD fault threshold corresponding with the at least one OBD signal. The apparatus also includes a regeneration module that is configured to regenerate the DEF decomposition tube according to the issued request. | 06-23-2011 |
Robert Frederic Kern, Otter Rock, OR US
Patent application number | Description | Published |
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20080256309 | MAINTAIN OWNING APPLICATION INFORMATION OF DATA FOR A DATA STORAGE SYSTEM - A data storage system writes data supplied from a host to data storage in accordance with write I/O of an owning application. A workload manager directs the processing of the supplied data in accordance with the write I/O of the owning application, provides service workload identification describing the write I/O, a storage subsystem control adds the service workload identification to record set information for the data, and a journal management system stores the record set information in a journal. The journaled information, for example, may be employed for performing forensic analysis of data corruption events or to perform security audits, etc. | 10-16-2008 |
20080256310 | MAINTAIN OWNING APPLICATION INFORMATION OF DATA FOR A DATA STORAGE SYSTEM - A data storage system writes data supplied from a host to data storage in accordance with write I/O of an owning application. A workload manager directs the processing of the supplied data in accordance with the write I/O of the owning application, provides service workload identification describing the write I/O, a storage subsystem control adds the service workload identification to record set information for the data, and a journal management system stores the record set information in a journal. The journaled information, for example, may be employed for performing forensic analysis of data corruption events or to perform security audits, etc. | 10-16-2008 |
20090083853 | METHOD AND SYSTEM PROVIDING EXTENDED AND END-TO-END DATA INTEGRITY THROUGH DATABASE AND OTHER SYSTEM LAYERS - Providing extended or end-to-end data integrity through layers of a system. In one aspect, information is to be transmitted between an application end of the system and a physical storage medium that stores the information for a database of the system, the information to be transmitted via a database server in a database server layer of the system. At least a portion of data protection is provided for the information, the data protection causing the information to be protected from corruption between a system layer and the physical storage medium, where the system layer is a separate layer provided closer to the application end of the system than the database server layer. | 03-26-2009 |
20120079224 | MAINTAINING MIRROR AND STORAGE SYSTEM COPIES OF VOLUMES AT MULTIPLE REMOTE SITES - Provided are a computer program product, system, and method for maintaining mirror and storage system copies of volumes at multiple remote sites. A first server maintains a mirror copy relationship in a computer readable storage medium between a first storage system at a first site and a second storage system at a second site to mirror data at the first storage system to the second storage system, wherein the first and second sites connect over a network. The first server performs a first point-in-time copy operation from the first storage system to a first storage system copy, wherein the data for the first storage system copy is consistent as of the determined point-in-time, wherein the point-in-time copy operation is completed upon creating a data structure indicating data for the first storage system copy as located at the first storage or the first storage system copy. The first server transmits a command to a second server to create a point-in-time copy of the second storage system. The second server processes mirror data transferred from the first server as part of the mirror copy relationship to determine when to create a second point-in-time copy from the second storage system to a second storage system copy in response to the command. The second server performs the second point-in-time copy operation, in response to determining from the mirror data to create the second point-in-time copy. | 03-29-2012 |
20120226877 | MAINTAINING MIRROR AND STORAGE SYSTEM COPIES OF VOLUMES AT MULTIPLE REMOTE SITES - Provided is a method for maintaining mirror and storage system copies of volumes at multiple remote sites. A first server maintains a mirror copy relationship between a first storage system at a first site and a second storage system at a second site. The first server performs a first point-in-time copy operation from the first storage system to a first storage system copy, wherein the data for the first storage system copy is consistent as of the determined point-in-time. The first server transmits a command to a second server to create a point-in-time copy of the second storage system. The second server processes mirror data transferred from the first server as part of the mirror copy relationship to determine when to create a second point-in-time copy. The second server performs the second point-in-time copy operation. | 09-06-2012 |
Robert L. Kern, Ashland, OH US
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20100215449 | Drilling Apparatus - Disclosed is an automated drill apparatus composed of one or more gang drills mounted to a gang drill chassis, at least one powered drive wheel affixed to the gang drill chassis, and at least three pivotable support wheels. A control panel provides remote operation of drill rotation activation, drill advance, and drill bed position adjustment, and a panic off switch. A control system implements steering the automated drill apparatus and is selectable by the operator for steering in two-wheel mode or crab steer mode. The pivotable drive wheels, in conjunction with the control panel and control system, are used to position the automated drill apparatus along a slab to be drilled, and further activate one or more gang drills for drilling a slab. | 08-26-2010 |
Rodney Kern, Dubuque, IA US
Patent application number | Description | Published |
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20100132264 | BI-FLOW INFLATABLE DOOR SEALS - An example of an inflatable seal for a door includes a bi-directional airflow pattern of frost-inhibiting heated air. The bi-directional flow pattern enables the seal's discharge opening and supply air blower to both be located well above the floor and preferably above the doorway. If the discharge opening is near the suction inlet of the blower, such an arrangement makes it possible to recover previously heated air by returning some of the warm air back to the blower. In some examples, the seal includes a supply air conduit and a return air conduit with one disposed within the other. The internal conduit may include a relatively stiff elbow to prevent that conduit from becoming kinked near an upper corner of the door. | 06-03-2010 |
Royden Thomas Kern, Lexington, KY US
Patent application number | Description | Published |
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20080219709 | Toner Metering Apparatus - The present disclosure relates to a device and/or method for conveying a quantity of image forming material between selected regions in a printing device or printer cartridge. A roller is provided having a surface that may include a recess capable of transferring a quantity of image forming material. The recess may include a convex surface. A wiper is configured to engage at least a portion of the roller surface and/or the convex surface in the recess to assist in the removal of image forming material that may otherwise accumulate on the roller surfaces. Such roller design and wiper configuration may therefore cooperate to improve the consistency of image forming material transfer. | 09-11-2008 |
20100266314 | Rotating Toner Cleaning Member for a Toner Delivery Device in an Image Forming Apparatus - The present invention provides a toner container system, such as a toner cartridge, comprising a housing including a first reservoir for containing toner and a second reservoir for receiving toner from the first reservoir and transferring the toner to an image forming apparatus, and a toner transfer mechanism that includes a rotatable roller member having in the surface thereof a recess defined by a concave surface having a radius of curvature, and wherein the roller member is rotatable from a first position at which the recess is open to the first reservoir and a second position at which the recess is open to the second reservoir, for conveying toner from the first reservoir to the second reservoir upon rotation of the roller member from the first position to the second position, and a rotatable wiper member disposed within the second reservoir and being sized and having a flexible distal end rotatable through the recess in contact with the concave surface when the roller member is in the second position. | 10-21-2010 |
20100266315 | Geneva Drive and Locking Mechanism Therefor in a Toner Metering Mechanism for an Image Forming Apparatus - The present invention provides a toner container system, such as a toner cartridge, having a first reservoir for containing toner and a second reservoir for receiving toner from the first reservoir and transferring the toner to an image forming apparatus, and a toner transfer mechanism disposed between the first and second reservoirs, the transfer mechanism including a generally cylindrically shaped rotatable roller member having a plurality of equally spaced recesses disposed around the circumference thereof and being rotatable in angular increments wherein the recesses are alternately open to the first reservoir in a first position for each recess and open to the second reservoir in a second position for each recess, whereby toner is transferred from the first reservoir to the second reservoir upon rotation of the roller member, a Geneva drive mechanism including a drive gear operatively connected to the roller member for advancing the roller member in one angular increment for each complete rotation of the drive gear; and a locking mechanism operatively interconnecting the drive gear and rotatable member, whereby the drive gear is intermittently locked after each incremental angular advancement of the roller member to prevent actuation of the toner transfer mechanism while the rotatable member rotates through a recess at the second position thereof. | 10-21-2010 |
20110293319 | Tubular Skiving Seal for a Rotary Toner Metering Mechanism - A toner container system includes a reservoir for containing toner having a rotatable member positioned within an opening through the reservoir and a skiving seal for blocking toner from entering a gap between the opening and the rotatable member. The skiving seal is positioned along the length of the rotatable member and is adhesively affixed adjacent to the rotatable member along the gap in the skiving direction of rotation of the rotatable member. The skiving seal includes a flexible sheet having a length corresponding to the length of the gap and a tubular portion adjacent to the gap formed by folding the flexible sheet over itself from an edge extending along the length of the flexible sheet, without creasing the fold, and adhering a portion of the folded portion of the flexible sheet to the surface of the flexible sheet along the length of the flexible sheet. | 12-01-2011 |
20130156462 | Tubular Skiving Seal for a Rotary Toner Metering Mechanism and Methods for Forming the Tubular Skiving Seal - A skiving seal for blocking toner from entering a gap between adjacent a rotatable member in a toner container system of an image forming apparatus. The skiving seal includes a flexible sheet having a surface and a length. The skiving seal includes a tubular portion formed by folding the flexible sheet over itself from an edge extending along the length of the flexible sheet without creasing the fold and adhesively adhering a portion of the folded portion of the flexible sheet to the surface of the flexible sheet along the length of the flexible sheet. The skiving seal includes an adhesive-coated area unobstructed on the surface of the flexible sheet for adhesively affixing the skiving seal in the toner container system. | 06-20-2013 |
Sam Kern, Collierville, TN US
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20110219509 | Two Handed Protective Covering - A protective covering that envelopes the left and right hands, wrists and lower forearms of a user and permits entry of an elongated handle of an object to be manipulated and gripped by the user within the covering. | 09-15-2011 |
Scott Kern, Hunt Valley, MD US
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20120034318 | DIAGNOSTIC METHOD USING PALB2 - The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient. | 02-09-2012 |
20120115735 | Pathways Underlying Pancreatic Tumorigenesis and an Hereditary Pancreatic Cancer Gene - There are currently few therapeutic options for patients with pancreatic cancers and new insights into the pathogenesis of this lethal disease are urgently needed. To this end, we performed a comprehensive analysis of the genes altered in 24 pancreatic tumors. First, we determined the sequences of 23,781 transcripts, representing 20,583 protein-encoding genes, in DNA from these tumors. Second, we searched for homozygous deletions and amplifications using microarrays querying ˜one million single nucleotide polymorphisms in each sample. Third, we analyzed the transcriptomes of the same samples using SAGE and next-generation sequencing-by-synthesis technologies. We found that pancreatic cancers contain an average of 63 genetic alterations, of which 49 are point mutations, 8 are homozygous deletions, and 6 are amplifications. Further analyses revealed a core set of 12 regulatory processes or pathways that were each genetically altered in 70% to 100% of the samples. The data suggest that dysregulation of this core set of pathways is responsible for the major features of pancreatic tumorigenesis. | 05-10-2012 |
20130074201 | CANCER-SPECIFIC GENETIC REARRANGEMENTS - The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods useful for treating cancer characterized by the expression of mutant FAM190A proteins. In a specific embodiment, a method for treating a patient having a cancer characterized by a FAM190A intragenic rearrangement comprises the step of administering to the patient an agent that inhibits a biological function or reduces the level or expression of the FAM190A protein. | 03-21-2013 |
Scott E. Kern, Hunt Valley, MD US
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20100305001 | FUNCTIONAL ASSAY FOR INDENTIFICATION OF LOSS-OF-FUNCTION MUTATIONS IN GENES - Provided herein are compositions and methods for assaying the deleteriousness of putative loss-of-function mutations, especially in genes known to be or suspected of being tumor-suppressor genes. The invention includes syngeneic variance libraries and methods of construction and use of syngeneic variance libraries. | 12-02-2010 |
Steven Tod Kern, Larchmont, NY US
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20120173453 | System and method for establishing a structured investment - A structured investment product provides a return that substantially tracks returns from at least two different financial instruments. To establish the structured investment product a forward starting option on a first financial variable is acquired at a first time. A financial instrument is also acquired. Purchase orders for shares of the structured investment and investment capital are received. At a second time, options on the first financial variable are acquired. Certain predefined terms of the forward starting option and certain predefined terms of the option are the same. More of the financial instrument is acquired. | 07-05-2012 |
William E. Kern, Wamego, KS US
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20120091085 | Storage Apparatus - A storage apparatus includes an elongate support rod pivotally mounted to a roof or ceiling structure for movement between a storage configuration adjacent and generally parallel to a ceiling and an extended configuration generally perpendicular to the ceiling. Upper and lower support members are attached to the support rod and are configured to removably hold items such as fishing rods. The support apparatus includes a capture member also mounted to the ceiling structure for releasably holding the support rod at the storage configuration. | 04-19-2012 |