Patent application number | Description | Published |
20080269451 | Antimicrobial Polymers - The present invention is concerned with providing antimicrobial compounds and processes for the production thereof. More particularly, the present invention provides antimicrobial polymeric materials comprising a polymer linked to a positively charged moiety via a carboxyl group. The present invention also provides processes for the production of such antimicrobial compounds and uses therefor. | 10-30-2008 |
20080299070 | Antiviral Compounds - The present invention relates to novel antiviral compounds which are covalently attached to solid, macro surfaces. In another embodiment, the invention relates to novel antiviral compositions including a polymeric material and, embedded therein, an antiviral compound. In other embodiments, the invention relates to making a surface antiviral and making a polymeric material antiviral. | 12-04-2008 |
20080300252 | EMBEDDING ANTIBIOTIC COMPOUNDS IN SOLID POLYMERS - The present invention is directed to providing antimicrobial compositions consisting of a polymeric material and, embedded therein, an antimicrobial compound. The antimicrobial compound contains at least one quaternary ammonium group, at least one hydrocarbon chain comprising a minimum of 10 carbon atoms and a maximum of 24 carbon atoms, and one or more anions to balance the charge of the quaternary ammonium groups. The invention is also directed to a method of making antimicrobial compositions containing an antimicrobial compound embedded in a polymeric material. | 12-04-2008 |
20090005386 | Methods for Modulating Ion Channels - In one embodiment, the invention provides an ion having the formula: (I) In another embodiment, the invention provides a method for modulating potassium, sodium, and cyclic nucleotide-modulated ion channels in a mammal in need thereof. In a further embodiment, the invention provides a method for modulating ligand-gated ion channels or transient receptor potential channels in a mammal in need thereof. The methods comprise administering an ion having the formula described above. | 01-01-2009 |
20090196847 | QUATERNARY AMMONIUM FUNCTIONALIZED GLYCODENDRIMERS, METHODS FOR THE PRODUCTION AND USE THEREOF - The present invention provides novel antimicrobial agents that are quaternary ammonium functionalized glycodendrimers. In one embodiment, the quaternary ammonium functionalized glycodendrimers are compounds of Formula (I): (Q | 08-06-2009 |
20090215917 | ANTIMICROBIAL POLYURETHANE FOAMS - This invention relates to antimicrobial polyurethane foams and to a method of making antimicrobial polyurethane foams. The invention also relates to the use of such foams in the production of medical devices and pharmaceutical compositions. | 08-27-2009 |
20090233935 | Methods for Fabrication of Antimicrobial Surfaces - A method for rendering a carboxyl-containing polymer surface resistant to microbial growth, the method comprising: (i) reacting the carboxyl-containing polymer surface with a metal borohydride in a solvent system comprising a water-soluble alcohol having one to three hydroxy groups and one to four carbon atoms, and optionally up to about fifty percent water, in a temperature range having a minimum of about 60° C. and a maximum of about 80° C., and for an amount of time sufficient for reducing carboxyl groups on the carboxyl-containing polymer surface to surface hydroxymethyl groups without altering the nature of the bulk of the polymer; and either: (iia) converting hydroxy groups of the surface hydroxymethyl groups to leaving groups and displacing the leaving groups with one or a combination of antimicrobial agents; or (iib) displacing the hydrogen atoms of the hydroxy groups of the surface hydroxymethyl groups with one or a combination of antimicrobial agents. | 09-17-2009 |
20100179156 | Antimicrobial compositions - The present invention is directed to providing antimicrobial surfaces containing 1,4-diazoniabicyclo[2.2.2]octane and hydrocarbon groups and/or chains. More specifically, the present invention is directed to antimicrobial compositions wherein the hydroxyl groups on polyols are replaced by 1,4-diazoniabicyclo[2.2.2]octane. The invention is also directed to methods of making antimicrobial compositions containing polyols. | 07-15-2010 |
20140294906 | METHOD FOR CONFERRING ANTIMICROBIAL ACTIVITY TO A SUBSTRATE - In one embodiment, the invention relates to a method for rendering a non-metallic substrate stably antimicrobial. The method comprises: (a) contacting the substrate with an antimicrobial surfactant; (b) contacting the substrate with a polymeric binder; and (c) subjecting the substrate, surfactant, and binder to conditions at which the substrate becomes stably antimicrobial. In another embodiment, the invention relates to a substrate into which an antimicrobial surfactant and a binder have penetrated. | 10-02-2014 |