Shendure
Jay Shendure, Chagrin Falls, OH US
Patent application number | Description | Published |
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20080269068 | MULTIPLEX DECODING OF SEQUENCE TAGS IN BARCODES - Methods and compositions for performing multiplex reactions are provided. | 10-30-2008 |
20090018024 | NANOGRID ROLLING CIRCLE DNA SEQUENCING - The present invention relates to methods for sequencing a polynucleotide immobilized on an array having a plurality of specific regions each having a defined diameter size, including synthesizing a concatemer of a polynucleotide by rolling circle amplification, wherein the concatemer has a cross-sectional diameter greater than the diameter of a specific region, immobilizing the concatemer to the specific region to make an immobilized concatemer, and sequencing the immobilized concatemer. | 01-15-2009 |
20100099080 | NUCLEIC ACID MEMORY DEVICE - This invention pertains to methods of imparting information onto nucleic acid sequences. In specific embodiments, the present invention provides site-specific recombinase systems and error-prone polymerase systems to alter nucleotide sequences such as DNA and mini-genomes, as well as for the production of microarrays. The present invention also provides methods of analyzing the modified nucleotides sequences provided herein. Methods of engineering and screening for novel modified polymerases that incorporate chain terminating nucleotides and/or labeled nucleotides more efficiently than wild-type polymerases are also provided. | 04-22-2010 |
Jay Shendure, Seattle, WA US
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20100069263 | SEQUENCE TAG DIRECTED SUBASSEMBLY OF SHORT SEQUENCING READS INTO LONG SEQUENCING READS - The invention provides compositions and methods for preparing DNA sequencing libraries. In particular, the method relates to preparing DNA sequencing libraries from kilobase scale nucleic acids. The invention also provides methods for assembling short read sequencing data into longer contiguous sequences. The method is useful for various applications in genomics, including genome assembly, full length cDNA sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes. | 03-18-2010 |
20120283110 | METHODS FOR RETRIEVAL OF SEQUENCE-VERIFIED DNA CONSTRUCTS - In some embodiments, methods of recovering a sequence-verified target nucleic acid are provided. In some embodiments, such methods may include tagging each member of a nucleic acid library with a set of adaptor sequences; sequencing the tagged members of the nucleic acid library; and recovering the sequence-verified target nucleic acid from the tagged and sequenced members of the nucleic acid library using a dial-out selection method. In certain embodiments, the members of the nucleic acid library may be tagged with a second set of adaptor sequences. | 11-08-2012 |
20130137588 | SEQUENCE TAG DIRECTED SUBASSEMBLY OF SHORT SEQUENCING READS INTO LONG SEQUENCING READS - The invention provides compositions and methods for preparing DNA sequencing libraries. In particular, the method relates to preparing DNA sequencing libraries from kilobase scale nucleic acids. The invention also provides methods for assembling short read sequencing data into longer contiguous sequences. The method is useful for various applications in genomics, including genome assembly, full length cDNA sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes. | 05-30-2013 |
20130137605 | SEQUENCE TAG DIRECTED SUBASSEMBLY OF SHORT SEQUENCING READS INTO LONG SEQUENCING READS - The invention provides methods for preparing DNA sequencing libraries by assembling short read sequencing data into longer contiguous sequences for genome assembly, full length cDNA sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes. | 05-30-2013 |
Jay Ashok Shendure, Seattle, WA US
Patent application number | Description | Published |
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20130203605 | MASSIVELY PARALLEL CONTIGUITY MAPPING - Contiguity information is important to achieving high-quality de novo assembly of mammalian genomes and the haplotype-resolved resequencing of human genomes. The methods described herein pursue cost-effective, massively parallel capture of contiguity information at different scales. | 08-08-2013 |
Rahul Shendure, Salt Lake City, UT US
Patent application number | Description | Published |
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20100264162 | FUEL COMPOSITION DISPENSING SYSTEM - The invention provides methods and systems for selecting and blending conventional fuel components into fuel compositions using an input system and for supplying a selected fuel composition into a storage container. The methods and systems incorporate a mixer to mix at least one conventional petroleum-derived fuel component received from the conventional fuel component supply system with at least one second non-petroleum fuel component received from the second fuel component supply to form fuel compositions. The present invention provides for systems and methods of supplying selected blends of conventional petroleum fuel with a non-petroleum derived fuel to provide greater consumer accessibility for petroleum blended with alternative fuels. | 10-21-2010 |