Patent application number | Description | Published |
20080267931 | Compositions for Silencing the Expression of Vdac1 and Uses Thereof - The present invention relates generally to the down regulation of mitochondrial protein, voltage-dependent anion channel (VDAC1), expression by RNAi or antisense therapy. In particular, the present invention is directed to VDAC1 silencing molecules useful in regulating cell proliferation and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant cell proliferation. | 10-30-2008 |
20080274962 | Voltage Dependent Anion Channel (Vdac1) Compositions and Methods of Use Thereof for Regulating Apoptosis - The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis. | 11-06-2008 |
20100075898 | N-TERMINAL VDAC VARIANTS AND USES THEREOF - The present invention relates generally to variants and peptides of the mitochondrial protein, voltage-dependent anion channel (VDAC) and to polynucleotides encoding same. In particular, the present invention is directed to N-terminal truncated and mutated VDAC and specific amino acid and polynucleotide sequences thereof useful in inhibiting apoptosis, and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with excess apoptosis. | 03-25-2010 |
20100092995 | FLUORESCENT RUTHENIUM COMPOUNDS FOR DETECTING CALCIUM BINDING PROTEINS - A fluorescent compound exhibiting a high affinity to calcium-binding proteins (CaBP) is provided. The compound, containing ruthenium, enables to detect, identify, and isolate CaBPs involved in cellular signaling and regulation. The compound is employed for diagnosing a disorder associated with CaBPs defects. | 04-15-2010 |
20120164730 | COMPOSITIONS FOR SILENCING THE EXPRESSION OF VDAC1 AND USES THEREOF - The present invention relates generally to the down regulation of mitochondrial protein, voltage-dependent anion channel (VDAC1) expression by RNAi or antisense therapy. In particular, the present invention is directed to VDAC1 silencing molecules useful in regulating cell proliferation and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant cell proliferation. | 06-28-2012 |
20120214741 | VDAC1 COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS - The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC), polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis. | 08-23-2012 |
20140186837 | Methods For Diagnosing Cancer - Methods and kits for the detection of cancer and for pre-cancer screening based on the expression of genes associated with altered metabolism and apoptosis in cancerous cells, particularly the expression of a mitochondrial antiviral-signaling (MAVS) or a voltage-dependent anion channel 1 (VDAC1) protein or mRNA in combination with additional genes associated with cell metabolism and/or apoptosis. | 07-03-2014 |
Patent application number | Description | Published |
20140281889 | RESEARCH DATA COLLECTOR AND ORGANIZER (RDCO) - A data source, such as a web page, a locally retrieved document, user-entered information, etc., is made visible to a user via a display, such as a computer monitor or touch-screen tablet or smart phone screen. The user selects data of interest from the display and indicates its type to a collection routine, which runs either overlaid onto the frame as a template being viewed by the user, or in the background. The collection routine then automatically associates the data with the corresponding field of a database. A later user may then view not only the current data record, but others, so as to see an organized compilation of information from multiple data sources. The collection routine may also enable multi-user and multi-source input. | 09-18-2014 |
20140317155 | RESEARCH DATA COLLECTOR AND ORGANIZER - A data source, such as a web page, a locally retrieved document, user-entered information, etc., is made visible to a user via a display, such as a computer monitor or touch-screen tablet or smart phone screen. A data capture window, which may be in the form of a data grid, is also displayed to the user, who can select data items from the data source such that they are represented in the data grid. Some data items may also be identified and collected automatically. Data collected into the capture window is then associated with corresponding portions of records in a data base. | 10-23-2014 |