Mcilwain
Blake Mcilwain, Houston, TX US
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20090278105 | FENCE ASSEMBLY - A fence assembly comprising a fence post having an upper support junction and a lower support junction. A fence frame includes an upper traverse rail joined to a lower traverse rail. Connection of the upper traverse rail to the fence post uses an upper rail connector having rotation relative to the upper support junction and connected therewith using an elongate connector inserted through the upper rail connector that includes a protrusion received by the upper traverse rail for connection at the upper support junction of the fence post. Likewise, connection of the lower traverse rail to the fence post uses a lower rail connector having rotation relative to the lower support junction and connected therewith using an elongate connector inserted through the lower rail connector that includes a protrusion received by the lower traverse rail for connection at the lower support junction of the fence post. | 11-12-2009 |
David Mcilwain, Toronto CA
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20150241429 | IRHOM2 INHIBITION FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS - Disclosed are methods for treating a subject with a Complement mediated (e.g., C5a mediated) disease or an immune complex mediated disease. The method comprises the step of administering to the subject an effective amount of an agent that decreases the biological activity of iRhom2 or an agent that modulates formation of a complex between iRhom2 and TACE. Also disclosed are assays for identifying such agents. | 08-27-2015 |
20150316538 | TREATMENT OF EGF-RECEPTOR DEPENDENT PATHOLOGIES - Disclosed are methods for treating a subject with an EGFR dependent pathology. The method comprises the step of administering to the subject an effective amount of an agent (“First Agent”) that decreases the biological activity of iRhom1 and an effective amount of an agent (“Second Agent”) that decreases the biological activity of iRhom2. Alternatively, the method comprises the step of administering to the subject an effective amount of an agent (“First Agent”) that modulates formation of a complex between iRhom 1 and TACE and an effective amount of an agent (“Second Agent”) that modulates formation of a complex between TACE and iRhom2. Also disclosed are assays for identifying such agents. | 11-05-2015 |
Doug Mcilwain, Uttoxeter GB
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20160090282 | BOOM ASSEMBLY WITH YAW ADJUSTMENT - A boom of a wheeled loader or digger is pivoted about a horizontal axis in a fork. Yaw adjustment is provided by opposed taper plugs which constitute a spindle of the boom. The taper portions of the plugs are eccentric with respect to the bearing portions and may be rotationally adjusted to correct misalignment of the boom in yaw. A threaded fastener locks the taper plugs to the boom. | 03-31-2016 |
Douglas Graham Mcilwain, Savannah, GA US
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20130052895 | Water sporting device having retractable fins - A water sport flotation device having an upper surface directed toward a user, an opposing bottom surface directed toward the water, and a pair of stabilizing fins, each fin having a top portion and a bottom edge. The flotation device further including a plurality of longitudinally disposed through slots in the upper surface and bottom surface, each slot partially surrounding each fin, and a flexible, resilient biasing means attached to the top portion of each fin and affixed to the upper surface so that the biasing means applies a downward force on each fin. The biasing means allows the bottom edge of the fin to retract through the slot and parallel to the bottom surface, if necessary, if the flotation device encounters an object in the water. | 02-28-2013 |
Irwin D. Mcilwain, Lancaster, PA US
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20080264025 | Header height sensor apparatus for a header of an agricultural harvester - A plurality of elongate mounting brackets mounted in cantilever relation on a frame of a header at sidewardly spaced locations across at least a portion of a width of the header, respectively, support a sensor rod for rotation about its axis. Each of the brackets has a free end including a bearing having a bore therethrough which receives the sensor rod, at least some of the bearings being self-aligning bearings. The self-aligning capability enables accommodating irregularities in the mounting locations for the brackets, and also bends, flexure and other deformities of the header frame and sensor rod, for achieving free rotatability of the sensor rod. This mounting arrangement also facilitates installation by one person, from the bottom side of the header, both initially and in the field. Additionally, the brackets can include features for aligning the bores of the bearings, to facilitate the installation and free rotation of the sensor rod when installed. | 10-30-2008 |
20110173944 | REPLACEABLE GUIDE ASSEMBLY TINES FOR AN AGRICULTURAL HARVESTER - An agricultural harvester is provided that Includes a frame carrying a structure movable about an endless path to deliver a crop to a header. The frame includes a guide assembly including a guide member supported by the frame. The frame also includes at least one tine secured to the guide member without extending through the guide member, and the at least one tine extending from the guide member above the structure to guide the crop between the at least one tine and the structure to the header. The at least one tine is installable and removable from the guide member without disconnecting the guide member from the frame. At least one tine is installable and removable from the guide member substantially without tools. | 07-21-2011 |
20110185694 | STABILIZATION SYSTEM FOR A CROP HARVESTING HEADER - A stabilization system used with a crop harvesting header includes a frame carrying a belt to deliver a crop to the header. The frame is independently movable between a first angle between the frame and the header and a second angle between the frame and the header. A member has an inside surface connectable in substantially non-rotational contact to a first structure of one of the frame or the header, and an outside surface connectable in substantially non-rotational contact to a second structure of the other of the frame or the header. In response to rotational movement of the first structure in substantially non-rotational contact with the inside surface, rotational movement of the first structure occurring with respect to the second structure in substantially non-rotational contact with the outside surface, the member provides a stabilizing torsional force between the frame and the header between the first and second angles. | 08-04-2011 |
20110232249 | FLEXIBLE MOTOR SUPPORT SYSTEM FOR A CROP GATHERING DEVICE HAVING A HARVESTING HEADER - A motor support system including a motor having a shaft rotatably secured to and maintained in a substantially axial alignment with a second shaft configured to change angular orientation along at least one plane of travel perpendicular to the axial alignment. The second shaft has a first pivot point with respect to a frame, the motor being secured to the frame by a cantilevered flexible member to maintain the motor shaft in substantial axial alignment with the second shaft | 09-29-2011 |
Kellie L. Mcilwain, Washington, DC US
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20090178153 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 07-09-2009 |
20110185439 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 07-28-2011 |
20110214189 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 09-01-2011 |
20130247233 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 09-19-2013 |
Michael E. Mcilwain, Idaho Falls, ID US
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20100084561 | Radioisotope Detection Device and Methods of Radioisotope Collection - A device for collection of radionuclides includes a mixture of a polymer, a fluorescent organic scintillator and a chemical extractant. A radionuclide detector system includes a collection device comprising a mixture of a polymer, a fluorescent agent and a selective ligand. The system includes at least one photomultiplier tube (PMT). A method of detecting radionuclides includes providing a collector device comprising a mixture comprising a polymer, a fluorescent organic scintillator and a chemical extractant. An aqueous environment is exposed to the device and radionuclides are collected from the environment. Radionuclides can be concentrated within the device. | 04-08-2010 |
Nate Mcilwain, Columbus, OH US
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20100114646 | Method and System for Segmenting Customers for Marketing and Other Projects - A customer segmentation technique automatically selects a customer score for customers from a plurality of predetermined customer scores during a daily processing sequence, allowing customer segmentation and performing marketing activities based on the customer score in the same daily processing sequence responsive to the customer score. The customer score encodes one or more customer status conditions that can be used by later functions in the daily processing sequence to guide marketing activities. | 05-06-2010 |
Ronald E. Mcilwain, Mclean, VA US
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20100193416 | Non-biological removal and recovery of nutrients from waste - An integrated process that includes liquid-solids separation and filtration system that treats swine or dairy feeding operations residual waste (manure flushwaters) for recovery of solid and dissolved nutrients for reuse and recycling of water from these wastes for a variety of uses. The system includes a coarse liquid/solids system to remove coarse material and multi stage, multimedia filter system that includes a set of modules. Each module includes screen assemblies and filter media sandwiched between the screen assemblies. A plurality of control assemblies is associated with each of the modules. The control assemblies include at least one external valve and are in fluid communication with a corresponding module to control flow through the corresponding module. The control assemblies selectively control fluid in each of the modules between at least one of: a forward flow through the screen assemblies to treat an influent flow, a bypass flow to bypass at least one of the modules, and a reverse flow provided through at least one of the modules. | 08-05-2010 |