Patent application number | Description | Published |
20090306186 | NOVEL TISSUE PROTECTIVE ERYTHROPOIETIN RECEPTOR (NEPOR) AND METHODS OF USE - There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. Presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, methods are provided for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Methods also are provided for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR). | 12-10-2009 |
20100286237 | PRO-ANGIOGENIC GENES IN OVARIAN TUMOR ENDOTHELIAL CELL ISOLATES - A gene profiling signature for ovarian tumor endothelial cells is disclosed herein. The gene signature can be used to diagnosis or prognosis an ovarian tumor, identify agents to treat an ovarian tumor, to predict the metastatic potential of an ovarian tumor and to determine the effectiveness of ovarian tumor treatments. Thus, methods are provided for identifying agents that can be used to treat ovarian cancer, for determining the effectiveness of an ovarian tumor treatment, or to diagnose or prognose an ovarian tumor. Methods of treatment are also disclosed which include administering a composition that includes a specific binding agent that specifically binds to one of the disclosed ovarian endothelial cell tumor-associated molecules and inhibits ovarian tumor in the subject. | 11-11-2010 |
20110064664 | METHODS AND COMPOSITIONS INVOLVING CHITOSAN NANOPARTICLES - Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the weight ratio of the chitosan to the polyphosphate is about 1.0 or greater and the weight ratio of the polyphosphate to the therapeutic agent or diagnostic agent is about 15.0 or less. Also disclosed are nanoparticles that include a chitosan and an inhibitor of enhancer of Zeste homologue 2 (EZH2). Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease and methods of predicting prognosis of ovarian cancer in a subject that involve determining the expression and/or function of EZH2 in the subject are also disclosed. | 03-17-2011 |
20120245087 | NOVEL TISSUE PROTECTIVE ERYTHROPOIETIN RECEPTOR (NEPOR) AND METHODS OF USE - There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. Presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, methods are provided for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Methods also are provided for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR). | 09-27-2012 |
20130274315 | PRO-ANGIOGENIC GENES IN OVARIAN TUMOR ENDOTHELIAL CELL ISOLATES - A gene profiling signature for ovarian tumor endothelial cells is disclosed herein. The gene signature can be used to diagnosis or prognosis an ovarian tumor, identify agents to treat an ovarian tumor, to predict the metastatic potential of an ovarian tumor and to determine the effectiveness of ovarian tumor treatments. Thus, methods are provided for identifying agents that can be used to treat ovarian cancer, for determining the effectiveness of an ovarian tumor treatment, or to diagnose or prognose an ovarian tumor. Methods of treatment are also disclosed which include administering a composition that includes a specific binding agent that specifically binds to one of the disclosed ovarian endothelial cell tumor-associated molecules and inhibits ovarian tumor in the subject. | 10-17-2013 |
20130296356 | COMBINATIONS - The present invention relates to a method of treating ovarian cancer in a female human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a ovarian cancer treatment method that includes administering 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof, and 2-[(5-chloro-2-[[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino]-4-pyridinyl)amino]-N-methoxybenzamide, or a pharmaceutically acceptable salt thereof, and optionally 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}, to a human in need thereof. | 11-07-2013 |
20140296318 | NOVEL TISSUE PROTECTIVE ERYTHROPOIETIN RECEPTOR (NEPOR) AND METHODS OF USE - Methods of determining whether a patient is suitable for erythropoietin (EPO) therapy, including (A) isolating a tissue sample from said patient; (B) determining the level of expression of EPH-B4 in said sample; and (C) correlating a presence of EPH-B4 expression to a negative physiological response to EPO therapy). In addition, methods of enhancing the effectiveness of EPO therapy in a patient by administering to said patient, in conjunction with EPO therapy, an siRNA specific for EPH-B4. | 10-02-2014 |
Patent application number | Description | Published |
20090012021 | Delivery of Sirna by Neutral Lipid Compositions - The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides methods for the delivery of a siNA (e.g., a siRNA) to a cell via a neutral (non-charged) liposome. These methods may be used to treat a disease, such as cancer. | 01-08-2009 |
20100172962 | THERAPEUTIC TARGETING OF INTERLEUKINS USING SIRNA IN NEUTRAL LIPOSOMES - The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein. | 07-08-2010 |
20110312899 | HDL Particles for Delivery of Nucleic Acids - Disclosed are high density lipoprotein-nucleic acid particles, wherein the particles include (a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region, wherein the positively-charged region of the polypeptide associates with the nucleic acid component. Also disclosed are pharmaceutical compositions that include a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region. Methods that concern the particles and pharmaceutical compositions of the present invention are also set forth, as well as kits. | 12-22-2011 |
20120070486 | METHODS AND COMPOSITIONS RELATED TO PREFOLDIN AND ITS REGULATION - The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides methods for the delivery of a siNA (e.g., a siRNA) to a cell to modulate expression of a PFDN 1-6. These methods may be used to treat a disease, such as cancer. | 03-22-2012 |
20130131076 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS - This application describes a novel technology in drug discovery and drug-based imaging/detection: the wrapping technology. This technology is based on identified singularities in the structure of soluble proteins. In contrast with drug-design approaches based on standard structural considerations, the packing of a protein, or more precisely, its dehydron pattern, may be used as a selectivity filter to design small-molecule inhibitors. The wrapping technology described herein is a novel form of rational drug design for avoiding side effects in drug therapy and sharpening the inhibitory impact of drugs on the oncokinome. | 05-23-2013 |
20140127326 | Detection of Cancer by Volatile Organic Compounds From Breath - Provided are methods for detecting a cancer, such as an ovarian cancer. In certain aspects, the methods involve detecting or measuring one or more volatile organic compounds (VOCs) from the breath of a subject. Apparatuses for the collection of VOCs are provided. | 05-08-2014 |
Patent application number | Description | Published |
20130331690 | VASCULAR IMAGING AGENTS - The present invention relates to a method of in vivo optical imaging, of the blood vessels and/or blood pool of a mammalian subject, which comprises an optical imaging contrast agent. The optical imaging agents comprise conjugates of far-red or near-infrared dyes with synthetic polyethyleneglycol (PEG) polymers having a molecular weight in the range 15-45 kDa. Also disclosed are methods of treatment monitoring, methods of diagnosis and medical uses involving the contrast agents. | 12-12-2013 |
20150285813 | CHEMICAL BLEACHING OF DYES USING RADICAL PHOTOINITIATORS - Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of binding at least one probe to one or more target present in a biological sample including multiple targets, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a photoinitiator and irradiating the sample, thereby initiating a photoactivated chemical bleaching process that substantially inactivates the probe. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, detecting and bleaching may be iteratively repeated. | 10-08-2015 |
20150316482 | PHOTOACTIVATED CHEMICAL BLEACHING OF DYES - Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample including multiple targets, binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with an electron transfer reagent, as well as an optional additive which prevents target modification during photoactivated chemical bleaching, and irradiating the sample, thereby initiating a photoreaction that substantially inactivates the probe by photoactivated chemical bleaching. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, defecting and bleaching may be iteratively repeated. | 11-05-2015 |
Patent application number | Description | Published |
20090044265 | Attack Resistant Continuous Network Service Trustworthiness Controller - An attack resistant continuous network service trustworthiness controller comprising: state estimation module(s), response selection module(s), actuation module(s), and client dispatcher communication module(s) for maintaining the availability and integrity of online server(s). The state estimation module(s) are configured to generate state estimate(s) for online server(s) using behavior data obtained using sensor module(s). The response selection module(s) are configured to determine corrective action(s) to maintain the availability and integrity of online server(s) when state estimate(s) indicate that the integrity of an online server(s) is compromised. The actuation module(s) are configured to activate actuator(s) based upon the corrective action(s). Client dispatcher communication module(s) are configured to communicate online server availability information to a client dispatcher. | 02-12-2009 |
20100161774 | Self-Cleansing Secure DNS Server - Disclosed is a self-cleansing intrusion tolerance-domain name systems system comprising at least three DNS servers, at least four storage systems accessible by the DNS servers, a communications link, a message transfer mechanism, and a self-cleansing mechanism. The storage systems include at least three online storage systems and at least one offline storage system. The communications link can connect the DNS servers with the storage systems, as well as connect the DNS servers with a local area network, which can connect the DNS servers with an external network. The message transfer mechanism can rotate the DNS servers into a plurality of roles, including a primary role, a secondary role, a designated role, and a self-cleansing role. The self-cleansing mechanism can be used to perform the self-cleansing role. | 06-24-2010 |
20100199122 | Cache Validating SCIT DNS Server - A cache validating SCIT-DNS Server including a server cluster, a cache copy, a controller and a validation module. Each of the servers in the server cluster uses a DNS mapping cache which maps DNS name(s) to record entry(ies). The cache copy maintains an image of DNS mapping cache(s). The controller manages the state of servers. States include a live spare state; an exposed state; a quiescent state; and a self-cleansing state. The validation module validates DNS entry(s) using a retriever module and a comparisons module. Retriever module retrieves an independent record entry associated with a selected DNS name from an external DNS resolver. The comparison module compares the independent record entry retrieved by the retriever module with the record entry associated with the selected DNS name residing in the cache copy. The validation module may cause server(s) to take an affirmative action in response to detected validation error(s). | 08-05-2010 |
20140053269 | ATTACK RESISTANT CONTINUOUS NETWORK SERVICE TRUSTWORTHINESS CONTROLLER - An attack resistant continuous network service trustworthiness controller comprising: state estimation module(s), response selection module(s), actuation module(s), and client dispatcher communication module(s) for maintaining the availability and integrity of online server(s). The state estimation module(s) are configured to generate state estimate(s) for online server(s) using behavior data obtained using sensor module(s). The response selection module(s) are configured to determine corrective action(s) to maintain the availability and integrity of online server(s) when state estimate(s) indicate that the integrity of an online server(s) is compromised. The actuation module(s) are configured to activate actuator(s) based upon the corrective action(s). Client dispatcher communication module(s) are configured to communicate online server availability information to a client dispatcher. | 02-20-2014 |
20150188893 | Secure Gateway - A secure gateway includes data storage for outgoing data and encrypted incoming data. SCIT server(s) rotate through unexposed mode(s) and exposed mode(s). If there is outgoing data in the data storage: the unexposed mode(s) retrieve outgoing data from the data storage; retrieve an encryption key from a key server; generate encrypted outgoing data by encrypting the outgoing data with the encryption key; delete the encryption key; and delete the outgoing data from the data storage. If there is encrypted incoming data in the data storage, the unexposed mode(s): retrieve encrypted incoming data from the data storage; retrieve a decryption key from the key server; generate incoming data by decrypting the encrypted incoming data with the decryption key; delete the decryption key; and delete the encrypted incoming data. The exposed mode: receives encrypted incoming data over an exposed interface; and transmits encrypted outgoing data over an exposed interface. | 07-02-2015 |
Patent application number | Description | Published |
20120249737 | DEVICE FOR OBTAINING STEREOSCOPIC IMAGES FROM A CONVENTIONAL ENDOSCOPE WITH SINGLE LENS CAMERA - The present invention discloses a device for obtaining stereoscopic images with conventional single optic channel endoscope using a single lens camera. The device comprises of an aperture each half of which is covered with complimentary additive and subtractive color filters and is installed between the endoscope and camera. The filters can be transversely adjusted to center on the principal ray so as to obtain optimal stereopsis. Images are viewed on a standard monitor using eyewear comprising the same complimentary additive and subtractive color filters on the left and the right side, or on specialized video monitors using active or passive polarized glasses. | 10-04-2012 |
20120265008 | SHAFT FOR ENDOSCOPE WITH A RIGID SURGICAL SUCTION AND DETACHABLE RETRACTOR BLADE FOR ENDOSCOPIC MICRO-NEUROSURGERY OF THE BRAIN - A shaft for endoscope for two handed micro neurosurgery of the brain comprising a Rigid surgical suction at 6 o′clock position that is longer than the shaft, Channel for endoscope at 12 o′clock position, Channel for irrigation, Surgical suction control hole on the shaft, a hand rest on the shaft and a detachable retractor blade. | 10-18-2012 |
20120277527 | Stereoscopic Imaging from a Conventional Endoscope with single lens camera - The present invention discloses an LCD device and viewing eyewear for obtaining stereoscopic images with conventional single optic channel endoscope using a single lens camera. LCD device comprises two segments each of which is activated by a controller through a wired or wireless connection and is installed between the endoscope and camera without affecting the optic path length. Images are viewed on a standard monitor using eyewear comprising LCD shutters on the left and the right side which are synchronized to the segments in the LCD device by a controller. The LCD shutters on the eyewear are in the upper inner field of vision of each eye. This allows the user, usually a surgeon, to have stereoscopic view when looking at the monitor, but clear view when he has to look at the operative field. The disclosed eyewear has a sterile attachment that the surgeon can use for mounting, un-mounting or adjusting the eyewear. | 11-01-2012 |
20130063813 | Method of viewing anaglyphs with single color filter to optimize color perception - The present invention discloses a method of improving color quality in anaglyphs. Stereo pair images are viewed using a filter of one primary color on the side corresponding to the side of the same color primary filter used in recording the anaglyph. The other side, corresponding to the side recorded using color filter of the remaining primary colors, has only a fixed or adjustable neutral density filter that matches the luminosity to that of the one primary color filter. Retinal rivalry suppresses the one primary color image on the side of the less luminous neutral density filter image, thus generating full stereopis. Since the side with the neutral density filter perceives all of the primary colors, the color gamut is maintained. | 03-14-2013 |
Patent application number | Description | Published |
20100108744 | CLOSED LOOP WIRE BONDING METHODS AND BONDING FORCE CALIBRATION - A method of applying bonding energy to form a bond between a portion of a wire and a contact of a bonding location using a wire bonding machine is provided. The method includes: (1) moving a bonding tool towards the contact; (2) detecting when a portion of the contact ( | 05-06-2010 |
20100181365 | METHOD OF TEACHING EYEPOINTS FOR WIRE BONDING AND RELATED SEMICONDUCTOR PROCESSING OPERATIONS - A method of teaching an eyepoint for a wire bonding operation is provided. The method includes ( | 07-22-2010 |
20110174865 | METHOD OF TEACHING EYEPOINTS FOR WIRE BONDING AND RELATED SEMICONDUCTOR PROCESSING OPERATIONS - A method of teaching an eyepoint for a wire bonding operation is provided. The method includes (1) selecting a group of shapes from a region of a semiconductor device for use as an eyepoint, and (2) teaching the eyepoint to a wire bonding machine using at least one of (a) a sample semiconductor device, or (b) predetermined data related to the semiconductor device. The teaching step includes defining locations of each of the shapes with respect to one another. | 07-21-2011 |
20120065761 | SYSTEMS AND METHODS FOR OPTIMIZING LOOPING PARAMETERS AND LOOPING TRAJECTORIES IN THE FORMATION OF WIRE LOOPS - A method of forming a wire loop in connection with a semiconductor package is provided. The method includes the steps of: (1) providing package data related to the semiconductor package to a wire bonding machine; (2) providing at least one looping control value related to a desired wire loop to the wire bonding machine, the at least one looping control value including at least a loop height value related to the desired wire loop; (3) deriving looping parameters, using an algorithm, for forming the desired wire loop; (4) forming a first wire loop on the wire bonding machine using the looping parameters derived in step (3); (5) measuring actual looping control values of the first wire loop formed in step (4) corresponding to the at least one looping control value; and (6) comparing the actual looping control values measured in step (5) to the at least one looping control value provided in step (2). | 03-15-2012 |
20120128229 | IMAGING OPERATIONS FOR A WIRE BONDING SYSTEM - A method of imaging a feature of a semiconductor device is provided. The method includes the steps of: (a) imaging a first portion of a semiconductor device to form a first imaged portion; (b) imaging a subsequent portion of the semiconductor device to form a subsequent imaged portion; (c) adding the subsequent imaged portion to the first imaged portion to form a combined imaged portion; and (d) comparing the combined imaged portion to a reference image of a feature to determine a level of correlation of the combined imaged portion to the reference image. | 05-24-2012 |
20150059957 | SYSTEMS AND METHODS FOR MEASURING PHYSICAL CHARACTERISTICS OF SEMICONDUCTOR DEVICE ELEMENTS USING STRUCTURED LIGHT - A method of determining a physical characteristic of an adhesive material on a semiconductor device element using structured light is provided. The method includes the steps of: (1) applying a structured light pattern to an adhesive material on a semiconductor device element; (2) creating an image of the structured light pattern using a camera; and (3) analyzing the image of the structured light pattern to determine a physical characteristic of the adhesive material. Additional methods and systems for determining physical characteristics of semiconductor devices and elements using structured light are also provided. | 03-05-2015 |
Patent application number | Description | Published |
20130154496 | MULTI-MODE FLYBACK CONTROL FOR A SWITCHING POWER CONVERTER - In at least one embodiment, an electronic system and method includes a controller to control a switching power converter in at least two different modes of operation depending on whether the controller detects a dimmer or not and/or whether a load requests more power than either of the two operational modes can provide. In at least one embodiment, the controller detects whether a dimmer is phase cutting an input voltage to a switching power converter. The controller operates the switching power converter in a first mode if the dimmer is detected, and the controller operates the switching power converter in a second mode if the dimmer is not detected. The controller also transitions between operating the switching power converter in the first mode and the second mode if a status of detection of the dimmer changes. | 06-20-2013 |
20140028095 | ACCELERATION OF OUTPUT ENERGY PROVISION FOR A LOAD DURING START-UP OF A SWITCHING POWER CONVERTER - An electronic system and method include a controller to operate in a start-up mode to accelerate driving a load to an operating voltage and then operates in a post-start-up mode. A start-up condition occurs when the controller detects that a load voltage is below a predetermined voltage threshold level. The predetermined voltage threshold level is set so that the controller will boost the voltage to an operating value of a load voltage at a faster rate than during normal, steady-state operation. The controller causes a switching power converter to provide charge to the load at a rate in accordance with a start-up mode until reaching an energy-indicating threshold. When the energy-indicating threshold has been reached, the controller causes the switching power converter to (i) decrease the amount of charge provided to the load relative to the charge provided during the start-up mode and (ii) operate in a distinct post-start-up-mode. | 01-30-2014 |
20140028213 | ACTIVE THERMAL PROTECTION FOR SWITCHES - A system and method include a controller that reduces power dissipated by a switch, such as a source-controlled field effect transistor, when an estimated amount of power dissipated by the switch exceeds a predetermined threshold. Reducing the power dissipated by the switch prevents damage to the switch due to overheating. The controller determines the estimated amount of power dissipated by the switch using actual drain-to-source current and drain voltage data. In at least one embodiment, the controller includes a fail-safe, estimated power dissipation determination path that activates when the drain voltage data fails a reliability test. Additionally, in at least one embodiment, the controller includes a model of thermal characteristics of the switch. In at least one embodiment, the controller utilizes real-time estimated power dissipation by the switch and the model to determine when the estimated power dissipated by the switch exceeds a power dissipation protection threshold. | 01-30-2014 |
Patent application number | Description | Published |
20110314543 | SYSTEM STATE BASED DIAGNOSTIC SCAN - In some embodiments, a local agent on a target system may evaluate current and/or historical system state information from a store (either local or remote) and dynamically adjust the level of diagnosis performed during the scan based on the evaluated state information. Individual diagnostic scans may, for example, be enabled and disabled based on the context in the store, and each scan may update the context for further evaluation. By employing such an approach, systems with a low risk profile and lacking symptoms of a problem may be scanned quickly while systems that show signs of a problem or have a high risk profile may receive a more thorough evaluation. | 12-22-2011 |
20130185799 | TRUSTED INSTALLATION OF A SOFTWARE APPLICATION - The trust reputation of the combination of an installation package and installer, as a pair, and the combination of a file and an installer, as a pair, is used to store the identity of a file in a persistent cache. An entry in the persistent cache indicates the trust worthiness of a file that does not contain malware thereby avoiding a scan of the file for malware. The trust worthiness of a file may be determined from known trust reputations of the installation package, installer, and file from a network of computing resources. By relying on the known trust reputation of the combination of the installation package and installer and the combination of the file and installer, the identity of the file may be stored in persistent cache quickly. | 07-18-2013 |
Patent application number | Description | Published |
20120249737 | DEVICE FOR OBTAINING STEREOSCOPIC IMAGES FROM A CONVENTIONAL ENDOSCOPE WITH SINGLE LENS CAMERA - The present invention discloses a device for obtaining stereoscopic images with conventional single optic channel endoscope using a single lens camera. The device comprises of an aperture each half of which is covered with complimentary additive and subtractive color filters and is installed between the endoscope and camera. The filters can be transversely adjusted to center on the principal ray so as to obtain optimal stereopsis. Images are viewed on a standard monitor using eyewear comprising the same complimentary additive and subtractive color filters on the left and the right side, or on specialized video monitors using active or passive polarized glasses. | 10-04-2012 |
20120265008 | SHAFT FOR ENDOSCOPE WITH A RIGID SURGICAL SUCTION AND DETACHABLE RETRACTOR BLADE FOR ENDOSCOPIC MICRO-NEUROSURGERY OF THE BRAIN - A shaft for endoscope for two handed micro neurosurgery of the brain comprising a Rigid surgical suction at 6 o′clock position that is longer than the shaft, Channel for endoscope at 12 o′clock position, Channel for irrigation, Surgical suction control hole on the shaft, a hand rest on the shaft and a detachable retractor blade. | 10-18-2012 |
20120277527 | Stereoscopic Imaging from a Conventional Endoscope with single lens camera - The present invention discloses an LCD device and viewing eyewear for obtaining stereoscopic images with conventional single optic channel endoscope using a single lens camera. LCD device comprises two segments each of which is activated by a controller through a wired or wireless connection and is installed between the endoscope and camera without affecting the optic path length. Images are viewed on a standard monitor using eyewear comprising LCD shutters on the left and the right side which are synchronized to the segments in the LCD device by a controller. The LCD shutters on the eyewear are in the upper inner field of vision of each eye. This allows the user, usually a surgeon, to have stereoscopic view when looking at the monitor, but clear view when he has to look at the operative field. The disclosed eyewear has a sterile attachment that the surgeon can use for mounting, un-mounting or adjusting the eyewear. | 11-01-2012 |
20130063813 | Method of viewing anaglyphs with single color filter to optimize color perception - The present invention discloses a method of improving color quality in anaglyphs. Stereo pair images are viewed using a filter of one primary color on the side corresponding to the side of the same color primary filter used in recording the anaglyph. The other side, corresponding to the side recorded using color filter of the remaining primary colors, has only a fixed or adjustable neutral density filter that matches the luminosity to that of the one primary color filter. Retinal rivalry suppresses the one primary color image on the side of the less luminous neutral density filter image, thus generating full stereopis. Since the side with the neutral density filter perceives all of the primary colors, the color gamut is maintained. | 03-14-2013 |