Patent application number | Description | Published |
20090148813 | Three-dimensional printing methods and materials for making dental products - This invention relates to ink-jet printing systems for making dental products such as artificial teeth, dentures, splints, veneers, inlays, onlays, copings, frame patterns, crowns and bridges and the like. An ink-jet printer is used to discharge wax-like polymerizable material in a layer-by-layer manner to build-up the object. In other methods, a heated capillary or dropper can be used to apply the polymerizable material. The resulting three-dimensional object has good dimensional stability. Light irradiation can be used to cure and harden the material, thereby producing the final dental product. | 06-11-2009 |
20090278285 | Light curing system and method - A method for light-curing polymerizable materials to form a dental device is provided. A light-curing apparatus having at least one integrated lighting and heating source, a curing volume, and a temperature controller, preferably a fan, is used in the method. The light source and temperature controller are used to heat a first polymerizable material to temperatures within a first temperature range. A second polymerizable material is applied on or adjacent to the first polymerizable material. The light source and temperature controller are used to heat the second polymerizable material to temperatures within a second temperature range. The first temperature range has a first midpoint and the second temperature range has a second midpoint. The first midpoint temperature is at least 10° C. apart from the second midpoint temperature. The system is particularly suitable for making dental devices such as full dentures, removable partial dentures, relines of full and partial dentures, nightguards, and occlusal splints. | 11-12-2009 |
20100044895 | Method of forming a dental product - The invention provides a method of shaping a dental product, comprising:
| 02-25-2010 |
20110049738 | Methods for making dental prosthesis by three-dimensional printing - This invention relates to methods for making a three-dimensional dental prosthesis using ink-jet printing systems. An ink-jet printer is used to discharge light-curable, wax-like polymerizable material in a layer-by-layer manner to build-up the prosthesis. The methods are particularly useful for making integrated dentures containing a set of artificial teeth. The denture base and set of teeth are made of light-curable, wax-like polymerizable materials comprising a mixture of monomer, oligomer, and light sensitizer. The wax-like materials are dimensionally stable in their uncured states. The denture base and artificial teeth are later light-cured to form a polymerized denture product having high flexural modulus and flexural strength. | 03-03-2011 |
20120129973 | HIGH STRENGTH DENTAL MATERIAL - The invention provides a high strength dental composition including polymerizable dental resins. The dental composition is useful as restorative material and for making various dental devices, such as artificial teeth, crowns and bridges of high strength dental polymeric material. | 05-24-2012 |
20120157566 | Hybrid polymer network compositions for use in dental applications - A dental appliance comprising a hard, shaped body having at least one portion comprising a polymerized blend of: From 0% to about 50% of an uncrosslinked polymer capable of dissolving in component;From about 0% to 50% of a monofunctional polymerizable monomer;From about 0% to 40% of a highly crosslinked polymer in the form of ground particles having average diameters up to about 500 microns;From about 0% to 50% of a crosslinked polymer in the form of discrete particles having average diameters up to about 500 microns and being easily swellable by said monomer; and From about 5% to about 35% of a di- or polyfunctional crosslinking agent. | 06-21-2012 |
Patent application number | Description | Published |
20080230167 | Adhesive and method for binding artificial plastic teeth - The present invention is directed toward an adhesive for and a method for bonding artificial plastic teeth to a denture base. The adhesive employs a number of adhesion promoter monomers, dimers or oligomers and a cure package, as well as methyl acetate as a solvent. The method according to the invention includes exposing a plastic tooth to the adhesive and allowing the plastic to soften (not dissolve). The adhesion promoter chains infiltrate the plastic tooth matrix, such that upon curing a secure bond is formed. | 09-25-2008 |
20090130624 | Methods and kits for making flexible dental guards - Dental guards, particularly night guards, used by patients to protect their teeth against the effects of grinding and bruxism are provided. Methods and kits for making such dental guards are also included. A light-curable polymerizable arch material is used to fabricate the dental guard. Preferably, the material contains polymerizable acrylic compounds, color-changing cure indicator, and particulate filler. The material is molded to conform to the shape of a dental arch of a patient and light-cured to form the dental guard. | 05-21-2009 |
20100286435 | Low shrinkage dental material and method - The invention provides a low polymerization shrinkage dental composition and a polymerizable dental material selected from the group consisting of wax-like dental material that undergoes ring open polymerization. The dental composition is useful as restorative material and for making artificial teeth, dentures, restoratives, crowns and bridges of high strength dental polymeric material. | 11-11-2010 |
20110081627 | Methods for making provisional and long-term dental crowns and bridges - The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, crowns and bridges. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office. A polymerizable dental composite material, which is dimensionally shape-stable in its uncured state, is used to make the restoration. A substructure such as a metal coping can be used to support the polymerizable material. The material includes a polymerizable acrylic compound, polymerization initiator system capable of being activated by light or heat, and preferably a filler material. The resulting dental restoration has good aesthetics, mechanical strength, and margins and contacts. | 04-07-2011 |
20110104641 | Shell forms for making provisional and long-term dental restorations - The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, implants, crowns and bridges. A shell or restoration form made of polymerizable material having good dimensional shape-stability in its uncured condition is used to make the dental restoration. A polymerizable material is introduced into the cavity of the shell form. The outer shell and injected polymerizable material are polymerized and bond together to form a hardened crown structure. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office. | 05-05-2011 |
20130213549 | ADHESIVE AND METHOD FOR BINDING ARTIFICIAL PLASTIC TEETH - The present invention is directed toward an adhesive for and a method for bonding artificial plastic teeth to a denture base. The adhesive employs a number of adhesion promoter monomers, dimers or oligomers and a cure package, as well as methyl acetate as a solvent. The method according to the invention includes exposing a plastic tooth to the adhesive and allowing the plastic to soften (not dissolve). The adhesion promoter chains infiltrate the plastic tooth matrix, such that upon curing a secure bond is formed. | 08-22-2013 |
20140103557 | SHELL FORMS FOR MAKING PROVISIONAL AND LONG-TERM DENTAL RESTORATIONS - The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, implants, crowns and bridges. A shell or restoration form made of polymerizable material having good dimensional shape-stability in its uncured condition is used to make the dental restoration. A polymerizable material is introduced into the cavity of the shell form. The outer shell and injected polymerizable material are polymerized and bond together to form a hardened crown structure. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office. | 04-17-2014 |
20140131908 | THREE-DIMENSIONAL FABRICATING MATERIAL SYSTEMS FOR PRODUCING DENTAL PRODUCTS - This invention relates to printable polymerizable material systems for making dental products such as artificial teeth, dentures, splints, veneers, inlays, onlays, copings, frame patterns, crowns and bridges and the like. A DLP or stereolithography printer is used to cure polymerizable material in a layer-by-layer manner to build-up the object. The resulting three-dimensional object has good dimensional stability. | 05-15-2014 |
20150038634 | IMPACT MODIFIED DENTURE BASE COMPOSITIONS - The present invention provides a composition including at least one polymerizable liquid component having at least one rubber impact modifier; at least one polymerization initiator, and at least one polymer component. | 02-05-2015 |
Patent application number | Description | Published |
20110111035 | INFLAMMATION-REGULATING COMPOSITIONS AND METHODS - The various embodiments provide a composition that provides local control over inflammation. The composition localizes the activities of the cytokine-neutralizing antibodies to the site of inflammation through covalent attachment to hydrophilic matrices. The various embodiments including a hydrophilic polymer, a ligand binding moiety covalently attached to the polymer, and optionally, a cellular adhesion peptide covalently attached to the polymer. The hydrophilic polymer may be a glycosaminoglycan such as hyaluronan. The cellular adhesion peptide may be a linear RGD peptide sequence covalently attached to the polymer. The ligand binding moiety may be a monoclonal antibody covalently attached to the polymer. The antibody may be selected from the group consisting of an anti-IL-1β, an anti-IL-6, an anti-TNF-α, and combinations thereof. The polymer functions as a substrate or matrix for cell migration and tissue regeneration. The RGD peptide functions to promote cellular proliferation, migration and attachment to the polymer. The monoclonal antibody functions to inhibit the inflammatory response. | 05-12-2011 |
20120064097 | Enhanced Binding of Pro-Inflammatory Cytokines by Polysaccharide-Antibody Conjugates - We provide monoclonal antibodies against interleukin-1β and tumor necrosis factor-α that remain biologically active in vitro when conjugated to high molecular weight polysaccharides. We report enhanced binding of these cytokines when their monoclonal antibodies are conjugated to alginate compared to non-conjugated monoclonal antibodies. In cell assays, polysaccharide-antibody constructs of the invention inhibited cytokine signaling to comparable levels as that of unmodified antibodies. Conjugation of cytokine-neutralizing antibodies to high molecular weight polymers enhances the affinities cytokine-binding moieties used as anti-inflammatory therapeutics. | 03-15-2012 |
20120282211 | ANTIBODIES AND CONJUGATES FOR MODULATORS OF ANGIOGENESIS - We provide methods and compositions for the treatment of dysregulation of blood vessel growth by regulation of neovascularization. Embodiments accomplish this by restricting the diffusion and transport of therapeutic agents through conjugating them to polymers or polymer constructs while retaining the binding affinities and functions of the therapeutic agents. | 11-08-2012 |
20130344129 | INFLAMMATION-REGULATING COMPOSITIONS AND METHODS - The various embodiments provide a composition that provides local control over inflammation. The composition localizes the activities of the cytokine-neutralizing antibodies to the site of inflammation through covalent attachment to hydrophilic matrices. The various embodiments including a hydrophilic polymer, a ligand binding moiety covalently attached to the polymer, and optionally, a cellular adhesion peptide covalently attached to the polymer. The hydrophilic polymer may be a glycosaminoglycan such as hyaluronan. The cellular adhesion peptide may be linear RGD peptide sequence covalently attached to the polymer. The ligand binding moiety may be a monoclonal antibody covalently attached to the polymer. The antibody may be selected from the group consisting of an anti-IL-1β, an anti-IL-6, an anti-TNF-α, and combinations thereof. The polymer functions as a substrate or matrix for cell migration and tissue regeneration. The RGD peptide functions to promote cellular proliferation, migration and attachment to the polymer. The monoclonal antibody functions to inhibit the inflammatory response. | 12-26-2013 |
Patent application number | Description | Published |
20080274505 | Polynucleotide encoding a novel TRP channel family member, LTRPC3, and splice variants thereof - The present invention provides novel polynucleotides encoding LTRPC3 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of LTRPC3 polypeptides, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention. | 11-06-2008 |
20080318257 | Polynucelotides encoding novel variants of the TRP channel family member, LTRPC3 - The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention. | 12-25-2008 |
Patent application number | Description | Published |
20080262335 | Skin screw electrode - Electrodes providing excellent recording and physical stability. The present invention encompasses electrodes that include a plurality of small teeth that possess a novel design shape and orientation. The shallow and relatively long teeth preferably run parallel to the rim of the electrode that presses against the patient's skin. When the electrode is twisted onto skin, the tiny teeth penetrate the stratum corneum and move nearly horizontally under the stratum corneum, thus anchoring the electrode securely to the skin. The electrodes of the present invention cause minimal discomfort to the patient since the small teeth do not extend to the pain fibers which are located in deeper layers of the skin. The electrodes may house a wide diversity of electronic components to enable numerous experimental and medical implementations. The electrodes the present invention may also be used wirelessly either singularly or as an array so that no electrode leads extend away from the patients body. The electrodes of the present invention may be fabricated using precision photo-chemical etching techniques that are well known in the art. The present invention also includes an electrode installation device that preferably employs the electrodes of the present invention. | 10-23-2008 |
20090005667 | ELECTRODE SYSTEMS, DEVICES AND METHODS - An electrode system include a flowable and cohesive surface contact element comprising a hydrophilic polymer swollen with an electrolyte fluid, the contact element having a Q′ ratio of at least 5 as defined by the equation | 01-01-2009 |
20090012433 | METHOD, APPARATUS AND SYSTEM FOR FOOD INTAKE AND PHYSICAL ACTIVITY ASSESSMENT - Electronic systems, devices and methods are provided to accurately measure both food intake and physical activity in a subject. A device is provided to be placed on a subject which records video as well as other physiological and/or environmental data. Video data can be analyzed along with other data obtained by the device to determine food consumption and physical activity of the subject, much of which is accomplished by automated computer-implemented processes. | 01-08-2009 |
20090171413 | IMPLANTABLE DEVICE, SYSTEM INCLUDING SAME, AND METHOD UTILIZING SAME - An implantable device. The implantable device includes a computing device, a microelectromechanical system (MEMS) pH sensor connected to the computing device, and a communication system connected to the computing device. | 07-02-2009 |
20110101788 | Wireless Energy Transfer System - A wireless energy transfer system includes a first energy transfer unit having at least one resonant frequency, a second energy transfer unit having the at least one resonant frequency, and a load. The first wireless energy transfer unit includes a first coil magnetically coupled to a first wireless energy transfer cell, and the second wireless energy transfer unit includes a second coil magnetically coupled to a second wireless energy transfer cell. The first coil receives first energy and through the magnetic coupling between the first coil and the first wireless energy transfer cell, the first wireless energy transfer cell is caused to generate second energy, wherein the second wireless energy transfer cell receives the second energy and through the magnetic coupling between the second wireless energy transfer cell and the second coil, the second coil is caused to provide third electromagnetic wave energy to the load. | 05-05-2011 |
20130267794 | Method, Apparatus and System for Food Intake and Physical Activity Assessment - Electronic systems, devices and methods are provided to accurately record and analyze food intake and physical activity in a subject. A device is provided to be placed on a subject which records video using at least two video cameras positioned to record stereoscopic image pair, as well as other physiological and/or environmental data including, for example, oxygen saturation, heart rate, and environmental factors such as physical location, temperature, and humidity. Video data is analyzed along with other data obtained by the device to determine food consumption and/or physical activity of the subject, much of which is accomplished by automated computer-implemented processes. | 10-10-2013 |
20130293025 | RESONANCE-BASED WIRELESS POWER TRANSFER SYSTEM - A wireless power transfer system including a driver coil array, a hexagonally-packed transmitter mat, a receiver coil, and a load coil for powering a medical implant. The magnetically coupled resonance between two isolated parts is established by an array of primary coils and a single small secondary coil to create a transcutaneous power link for implanted devices as moving targets. The primary isolated part includes a driver coil array magnetically coupled to a mat of hexagonally packed primary coils. Power is injected by the driver coils into the transmitter coils in the transmitter mat to maintain resonance in the presence of losses and power drawn by the receiver coil from the magnetic field. The implanted secondary isolated part includes a receiver coil magnetically coupled to a load coil. A rectification/filter system is connected to the load coil supplying DC power to the electronic circuits of the implant. | 11-07-2013 |
20140062212 | Wireless Energy Transfer System - A wireless energy transfer system includes a first energy transfer unit having at least one resonant frequency, a second energy transfer unit having the at least one resonant frequency, and a load. The first wireless energy transfer unit includes a first coil magnetically coupled to a first wireless energy transfer cell, and the second wireless energy transfer unit includes a second coil magnetically coupled to a second wireless energy transfer cell. The first coil receives first energy and through the magnetic coupling between the first coil and the first wireless energy transfer cell, the first wireless energy transfer cell is caused to generate second energy, wherein the second wireless energy transfer cell receives the second energy and through the magnetic coupling between the second wireless energy transfer cell and the second coil, the second coil is caused to provide third electromagnetic wave energy to the load. | 03-06-2014 |
20140187901 | ELECTRODE SYSTEMS, DEVICES AND METHODS - An electrode system include a flowable and cohesive surface contact element comprising a hydrophilic polymer swollen with an electrolyte fluid, the contact element having a Q′ ratio of at least 5 as defined by the equation | 07-03-2014 |
Patent application number | Description | Published |
20090306790 | Elastase Treatment of Tissue Matrices - A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time. | 12-10-2009 |
20100272782 | ACELLULAR TISSUE MATRIX COMPOSITIONS FOR TISSUE REPAIR - The invention provides tissue repair compositions and methods of making the tissue repair compositions. Also featured are methods of treatment using the tissue repair compositions and articles of manufacture that include the tissue repair compositions. | 10-28-2010 |
20110135706 | NERVE TREATMENT DEVICES AND METHODS - Devices and methods for treating defects in peripheral nerves are provided. The devices can include acellular arterial tissue matrices that facilitate regrowth of nerve tissue across a gap or defect in a peripheral nerve. | 06-09-2011 |
20110208320 | ABDOMINAL WALL TREATMENT DEVICES - Devices and methods for treating or repairing openings in an body wall are provided. The devices and methods can include acellular tissue matrices. The tissue matrices can be positioned within the abdominal opening and can be used to close the opening. | 08-25-2011 |
20110238186 | PREPARATION OF REGENERATIVE TISSUE SCAFFOLDS - Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response. | 09-29-2011 |
20120010728 | METHOD FOR SHAPING TISSUE MATRICES - Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents. | 01-12-2012 |
20140296623 | Preparation of Regenerative Tissue Scaffolds - Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response. | 10-02-2014 |
Patent application number | Description | Published |
20120059411 | DEVICE AND METHOD FOR TREATMENT OF INCISION OR HERNIA - Devices and methods for treating an abdominal incision or hernia are described. An implant for the restoration or prophylactic treatment of an abdominal wall comprises an elongate element and at least one sheet connected to the elongate element along a longitudinal axis of the elongate element. The elongate element is positioned along the line of incision, and the at least one sheet is secured to the abdominal muscles surrounding the incision. | 03-08-2012 |
20120263763 | REGENERATIVE MATERIALS - Methods of making tissue fillers are provided. In certain embodiments, the tissue is flake-like and has regenerative properties. | 10-18-2012 |
20130028984 | NATURAL TISSUE SCAFFOLDS AS TISSUE FILLERS - Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers. | 01-31-2013 |
20130121970 | METHOD FOR ELIMINATION OF SPACE THROUGH TISSUE APPROXIMATION - Acellular tissue matrix compositions for use in tissue approximation are provided. Also provided are methods for making and using the compositions to approximate tissue. | 05-16-2013 |
20130123920 | DEVICE FOR TENDON AND LIGAMENT TREATMENT - Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include acellular arterial tissue matrices that facilitate regrowth of the damaged tissue. | 05-16-2013 |
20130236439 | ENZYME-ACTIVATED COLLAGEN AND TISSUE MATRICES - Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include enzyme-activated acellular tissue matrices that facilitate regrowth of the damaged tissue. | 09-12-2013 |
20130280801 | FLOWABLE TISSUE MATRICES - Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized tissue or gelatin gel comprising partially or completely decellularized tissue or synthetic gelatin. The flowable tissue matrix compositions can contain factors that promote or enhance native cell migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the flowable tissue matrix compositions. The compositions can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration, and can promote or enhance native cell migration, proliferation, and/or revascularization. | 10-24-2013 |
20140004549 | Method for Enzymatic Treatment of Tissue Products | 01-02-2014 |
20140088701 | Processed Adipose Tissue - The present disclosure provides tissue products produced from adipose-containing tissues, as well as methods for producing such tissue products. The tissue products can comprise decellularized and partially de-fatted tissues. In addition, the present disclosure provides systems and methods for using such products. | 03-27-2014 |
20140186460 | Elastic Tissue Matrix Derived Hydrogel - A tissue-derived hydrogel, as well as methods of making and using such hydrogels, are provided. | 07-03-2014 |
Patent application number | Description | Published |
20140350310 | CATALYTIC PROCESS OF MAKING 1,3,3,3-TETRAFLUOROPROPENE - This disclosure relates to processes of making 1,3,3,3-tetrafluoropropene. The processes involve dehydrofluorinating 1,1,1,3,3-pentafluoropropane in vapor phase in the presence of a catalyst comprising a metal compound supported on alumina to produce a product mixture comprising 1,3,3,3-tetrafluoropropene, wherein said metal compound is selected from the group consisting of salts of sodium, potassium, zinc, magnesium, calcium, cobalt, copper, and chromium, and mixtures thereof. | 11-27-2014 |