Patent application number | Description | Published |
20080262033 | 4-Phenyl-5-Oxo-1,4,5,6,7,8- Hexahydroquinoline Derivatives as Medicaments for the Treatment of Infertility - The present invention- relates to 2-methyl-4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives having the general Formula (I) wherein the substituents are defined as in the description, or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives, as well as to the use of these 2-methyl-4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives in therapy, more specifically for the treatment of fertility disorders. | 10-23-2008 |
20080275042 | 4-Phenyl-5-Oxo-1,4,5,6,7,8-Hexahydroquinoline Derivatives for the Treatment of Infertility - The present invention relates to 4-phenyl-5-oxo-1,4)5,6,7,8-hexahydroquinoline derivatives according to Formula I, Formula I or a pharmaceutically acceptable salt thereof, wherein R | 11-06-2008 |
20080300270 | 4-Phenyl-5-Oxo-1,4,5,6,7,8,- Hexahydroquinoline Derivatives as Medicaments for the Treatment of Infertility - The invention relates to a 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivative according to Formula (I), wherein the substituents are defined as in the description, or a pharmaceutically salt thereof. The compounds of this invention are potent FSH receptor activators and may be used for treating fertility disorders in e.g. controlled ovarian hyperstimulation and IVF procedures. | 12-04-2008 |
20110028450 | Ring-annulated dihydropyrrolo[2,1-alpha]isoquinolines - The invention relates to ring-annulated dihydropyrrolo[2,1-a]isoquinoline compounds according to general Formula I | 02-03-2011 |
20110028451 | Dihydrobenzoindazoles - The invention relates to benzoindazole derivatives according to general Formula I | 02-03-2011 |
20110039832 | DIHYDRO)PYRROLO[2,1-A]ISOQUINOLINES - The invention relates to 5,6-dihydropyrrolo[2,1-a]isoquinoline and pyrrolo[2,1-a]isoquinoline derivatives according to general formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of infertility. | 02-17-2011 |
20110172267 | TSH receptor antagonizing tetrahydroquinoline compounds - The present invention relates the use of a compound, a pharmaceutical composition, compounds and a kit for treating or preventing disorders in a mammal responsive to TSH receptor mediated pathways, including disorders such as hyperthyroidism, Graves' disease, Graves Ophthalmopathy, Graves' associated pretibial dermopathy, nodular goitre and thyroid cancer comprising administering to said mammal an effective amount of a tetrahydroquinoline compound of Formula (I) or an pharmaceutically acceptable salt thereof. | 07-14-2011 |
20140256725 | FSH RECEPTOR ANTAGONISTS - The invention relates to FSH receptor antagonist according to general formula I or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders. | 09-11-2014 |
20140350043 | FSH RECEPTOR ANTAGONISTS - The invention relates to FSH receptor antagonist according to general formula (I) or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders. | 11-27-2014 |
20150329545 | FSH RECEPTOR ANTAGONISTS - The invention relates to FSH receptor antagonist according to general formula I | 11-19-2015 |
Patent application number | Description | Published |
20120309041 | Determination of Exosomel Biomarkers for Predicting Cardiovascular Events - The present invention relates to a method of predicting the risk of a subject developing a cardiovascular event, comprising determining the presence of a biomarker that is indicative of the risk of developing a cardiovascular event in exosomes from the subject. The exosomes are suitably isolated from a body fluid selected from serum, plasma, blood, urine, amniotic fluid, malignant ascites, bronchoalveolar lavage fluid, synovial fluid, breast milk, saliva, in particular serum. The biomarker is selected from the proteins Vitronectin, Serpin F2, CD14, Cystatin C, Plasminogen, Nidogen 2 or any combination of two or more of these proteins. | 12-06-2012 |
20140024046 | Exosomal Biomarkers for Cardiovasular Events - The present invention relates to a method of predicting the risk of a subject developing a cardiovascular event, comprising determining the presence of a biomarker that is indicative of the risk of developing a cardiovascular event in an exosome sample from the subject. The exosomes are suitably isolated from a body fluid selected from serum, plasma, blood, urine, amniotic fluid, malignant ascites, bronchoalveolar lavage fluid, synovial fluid, breast milk, saliva, in particular serum. Alternatively, the exosomes are present in a body fluid, in particular serum. The biomarker is selected from the proteins Vitronectin, Serpin F2, CD14, Cystatin C, Plasminogen, Nidogen 2, Serpin G1 or any combination of two or more of these proteins. The invention further relates to a method of diagnosing the occurrence of acute coronary syndrome in a subject, comprising determining the presence of a biomarker that is indicative of the occurrence of acute coronary syndrome in an exosome sample from the subject. In this method the biomarker is selected from Serpin F2, CD14, Cystatin C or combinations thereof. | 01-23-2014 |
Patent application number | Description | Published |
20110314169 | GROUP ACCESS TO IP MULTIMEDIA SUBSYSTEM SERVICE - A method of facilitating access to services of an IP Multimedia Subsystem network by user terminals and services located behind an access point to said network. The access point is associated with a subscription to the IP Multimedia Subsystem network. The method comprises including within an Implicit Registration Set defined for said subscription, a wildcarded Public User Identity, Public Service Identity, Public User Identity sub-domain representative of a range of Public User Identities, or Public Service Identity sub-domain representative of a range of Public Service Identities. At IP Multimedia Subsystem registration of said access point with the IP Multimedia Subsystem network, the Public User Identities and Service Identities contained in the Implicit Registration Set are distributed to a Serving Call Session Control Function allocated to said access point and to a Proxy Call Session Control Function to which said access point is attached. | 12-22-2011 |
20120011273 | GROUP ACCESS TO IP MULTIMEDIA SUBSYSTEM SERVICE - A method of facilitating access to services of an IP Multimedia Subsystem, by users groups that require alternative handling in relation to the standard handling of IP Multimedia Subsystem users. Functioning instructions are added to the user groups subscription maintained in the IP Multimedia Subsystem, instructing nodes in the IP Multimedia Subsystem to adapt their standard functioning for this specific group of users. The instructions in a subscription of a specific user group, provide a node of the IP Multimedia Subsystem that does no longer need to be specific for certain types of users, but has a standard way of operation, that is modified by instructions for dedicated operation for only that specific user group. In further aspect embodiments are disclosed providing improved solutions for known problems of IP Multimedia Subsystems making use of functioning instructions included in the subscription. | 01-12-2012 |
20120296953 | GROUP ACCESS TO IP MULTIMEDIA SUBSYSTEM SERVICE - A method of facilitating access to services of an IP Multimedia Subsystem, by users groups that require alternative handling in relation to the standard handling of IP Multimedia Subsystem users. Functioning instructions are added to the user group s subscription maintained in the IP Multimedia Subsystem, instructing nodes in the IP Multimedia Subsystem to adapt their standard functioning for this specific group of users. The instructions in a subscription of a specific user group, provide a node of the IP Multimedia Subsystem that does no longer need to be specific for certain types of users, but has a standard way of operation, that is modified by instructions for dedicated operation for only that specific user group. In further aspect embodiments are disclosed providing improved solutions for known problems of IP Multimedia Subsystems making use of functioning instructions included in the subscription. | 11-22-2012 |