Eastman, CA
Alan Eastman, Sunol, CA US
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20120279599 | Infrastructure Corrosion Analysis - The disclosure relates to systems, methods and apparatus for analyzing an infrastructure system including measurement of a parameter associated with the infrastructure system, electronically recording the measured parameter as a data, transferring the data to an infrastructure unit which may be remote from the infrastructure system, analyzing the data to generate a risk model, and predicting a characteristic of the infrastructure system according to the risk. An implementation plan may be generated, and/or maintenance services may be performed as per the characteristic that is predicted. | 11-08-2012 |
Brian Eastman, San Diego, CA US
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20080261921 | FUSED RING HETEROCYCLE KINASE MODULATORS - The present invention provides fused ring heterocycles as kinase modulators, pharmaceutical compositions containing these modulators, and methods of using these modulators to treat diseases mediated by kinase activity. | 10-23-2008 |
20090143352 | PYRROLO-PYRIDINE KINASE MODULATIORS - The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity. | 06-04-2009 |
20090258853 | Somatostatin Agonists - This invention relates to compounds which are agonists of somatostatin and selective toward somatostatin receptor subtype SSTR2. The compounds are useful in the treatment and prevention of diabetes, and diabetes-related pathologies, including retinopathy, neuropathy and nephropathy. Many of the compounds are orally active. Thus, it is an object of this invention to describe such compounds. It is a further object to describe the specific preferred stereoisomers of the somatostatin agonists. A still further object is to describe processes for the preparation of such compounds. Another object is to describe methods and compositions which use the compounds as the active ingredient thereof. | 10-15-2009 |
20100036118 | Fused Ring Heterocycle Kinase Modulators - The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity. | 02-11-2010 |
20100152098 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF - Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism. | 06-17-2010 |
20130316943 | BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF - Disclosed herein are polybasic bacterial efflux pump inhibitors containing boronic acid functionality and their methods of synthesis, methods of use, and pharmaceutical compositions. Some embodiments include methods of treating or preventing a bacterial infection by co-administering to a subject infected with bacteria or at risk of infection with bacteria the efflux pump inhibitor with another anti-bacterial agent. | 11-28-2013 |
Brian Eastman, Irvine, CA US
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20140261455 | STERILE DRAPE FOR A SURGICAL DISPLAY AND METHOD RELATED THERETO - A method of providing a sterile drape, and a sterile drape, for covering a display of a phacoemulsification console are disclosed. The method and the drape may include providing the sterile drape may be provided in a sterile package dedicated for a patient, enabling removal of the sterile drape from the package by a sterile user, providing a finger guard pocket in the sterile drape suitable for receiving fingers of the sterile user, and providing a fitted pocket to allow for fitting of the sterile drape over the display. | 09-18-2014 |
Brian J. Eastman, Irvine, CA US
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20140276372 | PHACOEMULSIFICATION FLOW RATE DETECTION SYSTEM AND METHOD - A phacoemulsification flow rate detection system and method for directly measuring the rate of fluid flowing into and out of the eye during a cataract operation. | 09-18-2014 |
20140378986 | FOOT PEDAL SYSTEM AND APPARATUS - A phacoemulsification system and method, and a foot pedal device, system and method. The devices, systems and methods may include a console comprising a plurality of modes for at least one physically associated surgical instrument, and a foot pedal communicatively associated with said console and suitable for varying ones of the plurality of modes. The foot pedal may include a foot pedal base, and at least two electronically actuated sensors physically associated with the foot pedal base, communicatively connected to the console, and suitable for receiving physical indications of variations in ones of the plurality of modes. | 12-25-2014 |
Brian W. Eastman, San Diego, CA US
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20080280899 | Inhibitors of Akt Activity - The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention. | 11-13-2008 |
20090062327 | Inhibitors of AKT Activity - The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer. | 03-05-2009 |
20090203903 | Thiazolyl mglur5 antagonists and methods for their use - The identification of a unique series of compounds which possesses special advantages in terms of drug-like properties due to their possessing advantageous properties in terms of potency and/or pharmacokinetic and/or selectivity and/or in vivo receptor occupancy properties. Specifically, the selection of a 1,3-thiazol-2-yl ring member linked by an ethynylene to the 3 position of a pyridyl ring or the 5 position of a pyrimidinyl ring, wherein the ring is substituted with selected substituents, results in a compound having superior drug-like properties. The invention includes pharmaceutically acceptable salt forms of these heterocyclic compounds, in particular chloride salts and trifluoroacetate salts. | 08-13-2009 |
20110230526 | Thiazolyl Mglur5 Antagonists and Methods for Their Use - The identification of a unique series of compounds which possesses special advantages in terms of drug-like properties due to their possessing advantageous properties in terms of potency and/or pharmacokinetic and/or selectivity and/or in vivo receptor occupancy properties. Specifically, the selection of a 1,3-thiazol-2-yl ring member linked by an ethynylene to the 3 position of a pyridyl ring or the 5 position of a pyrimidinyl ring, wherein the ring is substituted with selected substituents, results in a compound having superior drug-like properties. The invention includes pharmaceutically acceptable salt forms of these heterocyclic compounds, in particular chloride salts and trifluoroacetate salts. | 09-22-2011 |
20120289696 | THIAZOLYL MGLUR5 ANTAGONISTS AND METHODS FOR THEIR USE - The identification of a unique series of compounds which possesses special advantages in terms of drug-like properties due to their possessing advantageous properties in terms of potency and/or pharmacokinetic and/or selectivity and/or in vivo receptor occupancy properties. Specifically, the selection of a 1,3-thiazol-2-yl ring member linked by an ethynylene to the 3 position of a pyridyl ring or the 5 position of a pyrimidinyl ring, wherein the ring is substituted with selected substituents, results in a compound having superior drug-like properties. The invention includes pharmaceutically acceptable salt forms of these heterocyclic compounds, in particular chloride salts and trifluoroacetate salts. | 11-15-2012 |
Brock Eastman, Chico, CA US
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20140106686 | METHODS AND SYSTEMS FOR HIGH CAPACITY WIRELESS BROADBAND DELIVERY - System enhancement(s) are disclosed that can add capabilities, such as, using Frequency Division Multiple Access (FDMA) and/or Time Division Multiple Access (TDMA) and/or Frequency Division Duplex (FDD) capabilities along with Multi-Input Multi-Output (MIMO) antennas and/or Global Positioning System (GPS) synchronization. The use of two radios in both the base-station and the subscriber-station, i.e., customer premises equipment (CPE), e.g., can allow frequency division to be utilized, exploiting higher receive gains at the CPE while not affecting transmissions occurring on the other radio's frequency. | 04-17-2014 |
Darren Eastman, Cupertino, CA US
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20090177922 | DETECTION OF SYSTEM BATTERY ERRORS - In an example embodiment, a method is provided to identify an error associated with a system battery. This system battery is operably associated with a computing device and is used to power the computing device. A parameter of the system battery is tested and an error associated with the system battery may be detected. In an example, the error may be detected before the operating system is loaded onto the computing device. In another example, the error may be detected when the computing device is waking from a reduced power mode. | 07-09-2009 |
Jim Eastman, San Francisco, CA US
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20140266247 | TEST PATTERN MEMBRANE AND METHOD FOR TESTING CAPACITIVE SENSORS - A test pattern membrane test method uses a test pattern membrane to test the capacitive sensors of a device. The device is placed in the test fixture. The capacitive sensors are read without the test pattern membrane, storing as a set of baseline measurements. The test pattern membrane is placed on the unit to be tested. The test pattern membrane has a plurality of conductive areas on a non-conductive substrate. The conductive areas are arranged in a pattern that corresponds to the pattern of capacitive sensors. The sensors are read again to obtain a set of stimulated measurements. Differences for each of the sensors are determined between the sensor readings with and without the test pattern membrane in place. This difference is compared to a threshold. A sensor is considered to be functioning properly if the difference value is greater than the sensor's threshold value. | 09-18-2014 |
John Eastman, Santa Cruz, CA US
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20100321709 | AUTOMATED AUDIT SYSTEM, APPARATUS AND METHOD - A system, apparatus and method are provided to automate an audit of an information technology (IT) system. | 12-23-2010 |
20110016308 | ENCRYPTED DOCUMENT TRANSMISSION - Apparatuses, systems and methods are provided for secure transmission of data. | 01-20-2011 |
Jon Eastman, Beverly Hills, CA US
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20080288423 | SYSTEM AND METHOD FOR PROVIDING ACCESS TO A NETWORK - A method provides access to, and time for, using a network associated with a commercial establishment through a proxy server. The method enables access to the proxy server within a selected physical area adjacent to the commercial establishment; establishing data communication between a cash register within the commercial establishment and the proxy server; and enabling network access for a given time duration related to a commercial transaction between the customer and the commercial establishment. The transaction my include trade dealing in cash, airline miles or other point based system, certificates, coupons and any other trade related instrument. | 11-20-2008 |
Lisa Marie Eastman, Santa Rosa, CA US
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20140022774 | Decorative Candle Wrapper - A kit for the decoration of an imitation candle which includes a removable, replaceable, and reusable decorative wrapper which adheres to the surface of the candle and is translucent such that the glow of the imitation candle enhances the decorative design. The kit optionally includes an imitation candle and/or a holder for decorative wrappers that are not in use. | 01-23-2014 |
Paul Scott Eastman, Danville, CA US
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20100016175 | QUANTUM DOT-ENCODED BEAD SET FOR CALIBRATION AND QUANTIFICATION OF MULTIPLEXED ASSAYS, AND METHODS FOR THEIR USE - Control beads are disclosed that allow for improved quantitation of analytes in multiplexed bead assays. The control beads have a range of concentrations of calibration moieties that provide for the preparation of a titration curve. The titration curve can be used to quantify the concentration of the analytes. The titration curve can be used to correlate the signal obtained from a bead with the concentration (or absolute number of molecules) of the analyte bound to the bead. | 01-21-2010 |
20120065090 | QUANTUM DOT-ENCODED BEAD SET FOR CALIBRATION AND QUANTIFICATION OF MULTIPLEXED ASSAYS, AND METHODS FOR THEIR USE - Control beads are disclosed that allow for improved quantitation of analytes in multiplexed bead assays. The control beads have a range of concentrations of calibration moieties that provide for the preparation of a titration curve. The titration curve can be used to quantify the concentration of the analytes. The titration curve can be used to correlate the signal obtained from a bead with the concentration (or absolute number of molecules) of the analyte bound to the bead. | 03-15-2012 |