Patent application number | Description | Published |
20120020959 | USE OF THE SPARC MICROENVIRONMENT SIGNATURE IN THE TREATMENT OF CANCER - The invention provides multiparametric anti-SPARC antibody-based techniques for predicting the response to chemotherapy. | 01-26-2012 |
20120148613 | MULTIVALENT ENTRAIN-AND-AMPLIFY IMMUNOTHERAPEUTICS FOR CARCINOMA - The present invention provides a method of treating a cell proliferative disease such as cancer by providing to a subject in need thereof an immunogenic composition comprising plasmid and peptide(s) or analogues thereof. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response. | 06-14-2012 |
20130101504 | SPARC BINDING ANTIBODIES AND USES THEREOF - The invention provides SPARC binding antibodies that target disease sites, in particular, tumors and uses thereof to diagnose and treat diseases, in particular, cancerous tumors. | 04-25-2013 |
20130281376 | SPARC MICROENVIRONMENT SIGNATURE, PLASMA SPARC, AND LDH AS PROGNOSTIC BIOMARKERS IN THE TREATMENT OF CANCER - The invention provides multiparametric anti-SPARC antibody-based techniques for treating cancers as well as determining prognosis and predicting the response to therapy, including chemotherapy, radiotherapy, surgical therapy and combination therapies. | 10-24-2013 |
Patent application number | Description | Published |
20080293726 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 11-27-2008 |
20120123164 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 05-17-2012 |
20130065904 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 03-14-2013 |
20140315910 | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders - One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders. | 10-23-2014 |
Patent application number | Description | Published |
20090063638 | Method and Apparatus for Processing Messages in Messaging System - Techniques are disclosed for processing messages in a messaging system, particularly during an overload condition. For example, a method of processing messages of an instant messaging system includes the following steps. A message from a first instant messaging user is received during an overload condition. A message type associated with the received message is determined. The method then decides whether to send the message to a second instant messaging user based on the determined message type of the received message. In another method, processing messages in an instant messaging system includes the following steps. Presence information associated with a first instant messaging system user is received. The presence information is sent to a second instant messaging system user when the second messaging system user requests the presence information associated with the first instant messaging system user. | 03-05-2009 |
20090177779 | Methods and Apparatus for Randomization of Periodic Behavior in Communication Network - A technique for use in a client, wherein the client supports a state-based signaling protocol (e.g., Session Initiation Protocol or SIP), includes initiating a given session state between the client and a server that also supports the state-based signaling protocol, and refreshing the given session state in a randomized manner. Further, a technique for use in a server, wherein the server supports a state-based signaling protocol (again, e.g., SIP), includes randomly assigning an expiration time duration for a given session state between the server and a client that also supports the state-based signaling protocol, and reporting the randomly assigned expiration time for the given session state to the client. By randomizing various behaviors of the client, the server, or both, bursty traffic in the communication network is reduced or eliminated. | 07-09-2009 |
20100077018 | Virtual Presence Server - Techniques are disclosed for generating and managing presentities in accordance with a virtual presence server. By way of example, a method for requesting information from at least one server comprises the following steps. A client request, which expresses a request that can not be satisfied by a single existing presentity, is obtained at an intermediate server, wherein the intermediate server operates as a virtual presence server. The virtual presence server (i.e., intermediate server) creates a set of software objects for a virtual presentity, the set of objects embodying logic to combine presence information from one or more of existing presentities and external information sources, in accordance with at least one existing presence server. The virtual presence server creates an association between the request of the client and the created virtual presentity that allows the presence information to be propagated back to the client. | 03-25-2010 |
20110078290 | ENERGY-EFFICIENT SERVER LOCATION DETERMINATION FOR CONFIGURATION CHANGES - At a data center controller, a first server location is determined from a set of available server locations at which to change a server active state for a data center. A time and configuration change for the data center are forecasted. A second server location is determined from the set of available server locations at which to change the server active state based upon the forecasted configuration change for the data center. An available server location is selected at which to change the server active state based upon the first server location, the second server location, and the forecasted time associated with the forecasted configuration change for the data center. | 03-31-2011 |
20110078480 | ENERGY-EFFICIENT SERVER LOCATION DETERMINATION - A heat potential value for each of a set of available server locations is calculated via a data center controller based upon at least one active server in a data center. A minimal calculated heat potential value for the set of available server locations is identified. An available server location associated with the identified minimal calculated heat potential value is selected from the set of available server locations. | 03-31-2011 |
20110119367 | Methods and Apparatus for Randomization of Periodic Behavior in Communication Network - A technique for use in a client, wherein the client supports a state-based signaling protocol (e.g., Session Initiation Protocol or SIP), includes initiating a given session state between the client and a server that also supports the state-based signaling protocol, and refreshing the given session state in a randomized manner. Further, a technique for use in a server, wherein the server supports a state-based signaling protocol (again, e.g., SIP), includes randomly assigning an expiration time duration for a given session state between the server and a client that also supports the state-based signaling protocol, and reporting the randomly assigned expiration time for the given session state to the client. By randomizing various behaviors of the client, the server, or both, bursty traffic in the communication network is reduced or eliminated. | 05-19-2011 |
20110302292 | SYSTEMS AND METHODS FOR SERVICE ASSURANCE USING VIRTUALIZED FEDERATED PRESENCE INFRASTRUCTURE - Systems, methods, apparatuses and program products configured to provide a topology-service tool are described. A presence-federation solution asset is leveraged to address topology-federation problems. A network topology tool takes as input network endpoints, for example caller and callee telephone numbers, determines a network service flow used to connect the network endpoints, and develops a network topology view of the service flow along with associated network device related information. | 12-08-2011 |
20120166420 | SYSTEMS AND METHODS FOR CREATING SCALABLE PRESENCE SUBSCRIPTIONS IN FEDERATED PRESENCE ENVIRONMENTS - Systems and associated methods for providing scalable presence subscriptions in federated presence environments are described. Embodiments provide for intelligent addition of subscriptions to a presence system. Embodiments identify if a virtualized presentity (corresponding to a new query) can be composed from existing virtualized presentities, and if so, corresponding query processing cells (QPCs) (servicing existing queries) are reused to retrieve the presence information (partially or fully) for the new incoming query. Embodiments organize the existing QPCs into a hierarchy such that a QPC/virtual presentity at a higher layer fetches presence information of all or some presentities from QPCs/virtual presentities at lower layer(s) to service the new query. | 06-28-2012 |
20120272075 | ENERGY-EFFICIENT SERVER LOCATION DETERMINATION - A heat potential value for each of a set of available server locations is calculated via a data center controller based upon at least one active server in a data center. A minimal calculated heat potential value for the set of available server locations is identified. An available server location associated with the identified minimal calculated heat potential value is selected from the set of available server locations. A maximal calculated heat potential value is identified for the set of available server locations. An available server location associated with the identified maximal calculated heat potential value is selected from the set of available server locations. A server located at the selected available server location associated with the identified maximal calculated heat potential value is automatically de-energized. | 10-25-2012 |
20160077869 | EXTENDING CLOUD COMPUTING TO ON-PREMISES DATA - A method and system are provided. The method includes defining an application manifest that describes a computing solution for transfer from a cloud site to an on-premises computing appliance at a given premises. The computing solution is executable for a dataset resident at the given premises. The method further includes defining a characterization of a local premises environment in which the computing solution will be executed. The method also includes modifying the application manifest using the characterization of the local premises environment by at least one of adding, removing and modifying at least one component of the application manifest to provide a modified application manifest. The method additionally includes installing the computing solution in a computing appliance at the local premises environment according to the modified application manifest. The computing appliance is for executing the computing solution. | 03-17-2016 |
Patent application number | Description | Published |
20120079209 | METHOD AND APPARATUS FOR IMPLEMENTING MULTI-PROCESSOR MEMORY COHERENCY - A method and an apparatus for implementing multi-processor memory coherency are disclosed. The method includes: a Level-2 (L2) cache of a first cluster receives a control signal of the first cluster for reading first data; the L2 cache of the first cluster reads the first data in a Level-1 (L1) cache of a second cluster through an Accelerator Coherency Port (ACP) of the L1 cache of the second cluster if the first data is currently maintained by the second cluster, where the L2 cache of the first cluster is connected to the ACP of the L1 cache of the second cluster; and the L2 cache of the first cluster provides the first data read to the first cluster for processing. The technical solution under the present invention implements memory coherency between clusters in the ARM Cortex-A9 architecture. | 03-29-2012 |
20130282939 | METHOD AND APPARATUSES FOR MONITORING SYSTEM BUS - Embodiments of the present invention provide a method and apparatuses for monitoring a system bus. The method includes: performing, by a monitoring apparatus, real-time monitoring on a corresponding system bus, and when detecting that a command is transmitted through the system bus, obtaining command information; determining, according to the command information, whether a command transmission exception occurs in the system bus; if no command transmission exception occurs in the system bus, when detecting that data corresponding to the command is transmitted through the system bus, determining, according to the data and the amount of the data, whether a command exception occurs in the system bus; and when detecting that a response message corresponding to the command is transmitted through the system bus, obtaining a command wait time of the command, and determining, according to the command wait time, whether a timeout exception occurs in the system bus. | 10-24-2013 |