Patent application number | Description | Published |
20090088428 | CYCLOHEXYLIMIDIAZOLE LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 - The present invention discloses novel compounds of Formula I: (I) having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity. | 04-02-2009 |
20090111800 | CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 - The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity. | 04-30-2009 |
20090156571 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 - The present invention discloses novel compounds of Formula I: possessing 11 β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11 β-HSD type 1 activity. | 06-18-2009 |
Patent application number | Description | Published |
20080310585 | DETECTOR ARRAY AND SYSTEM - In some embodiments, an optical mask for a CT detector is disclosed. In some embodiments, the mask is intercalated between a photodiode array and a scintillator array forming the CT detector. In some embodiments, the optical mask may extend along one or more axes and differentially absorbs and/or reflects light emitted from the scintillators at edges of photodiodes forming the diode array, with less absorption or reflection at edges of tiled die forming the diode array than in central portions of each of the die. Through selective absorption and/or reflection, transference of light photons from a scintillator to the photodiode corresponding to a neighboring scintillator is spatially modified, at least partially compensating for spatial differences in crosstalk signals between adjacent pairs of photodiode/scintillator cell elements. This reduction in differential crosstalk reduces artifacts in a reconstructing data descriptive of internal portions of a subject, which improves diagnostic value of the data. | 12-18-2008 |
20120146174 | PHOTOSENSOR ASSEMBLY AND METHOD FOR PROVIDING A PHOTOSENSOR ASSEMBLY - A photodiode assembly includes a semiconductor substrate, a photodiode cell, a ground diffusion region, and a guard band. The photodiode cell includes a first volume of the substrate doped with a first type of dopant. The diffusion region includes a second volume of the substrate that is doped with a second, opposite type of dopant. The guard band is disposed in the substrate and at least partially extends around an outer periphery of the photodiode cell. The guard band includes a third volume of the substrate that is doped with the first type of dopant. At least one of the ground diffusion region or the guard band is conductively coupled with a ground reference to conduct one or more of electrons or holes that drift from the photodiode cell through the substrate. The guard band is disposed closer to the photodiode cell than the ground diffusion region. | 06-14-2012 |
Patent application number | Description | Published |
20110105092 | SYSTEMS AND METHODS FOR ENHANCING A USER VISIT TO A SITE PREMISES - Exemplary systems and methods for enhancing a user visit to a site premises are disclosed. An exemplary method includes a mobile device tracking a geographic location of the mobile device, accessing site data associated with a site premises, and providing an interactive user interface configured to enhance a visit of a user of the mobile device to the site premises based on the site data associated with the site premises and the geographic location of the mobile device within the site premises. In certain embodiments, an output may be selected based on the geographic location of the mobile device within the site premises and provided via the interactive user interface for experiencing by the user of the mobile device. Corresponding systems and methods are also disclosed. | 05-05-2011 |
20110106613 | ELECTRONIC COUPON DISTRIBUTION, COLLECTION, AND UTILIZATION SYSTEMS AND METHODS - Exemplary electronic coupon distribution, collection, and utilization systems and methods are disclosed. An exemplary method includes maintaining coupon data representative of at least one electronic coupon collected by a consumer, the coupon data accessible by a mobile computing device associated with the consumer, detecting an occurrence of a predetermined trigger event related to the at least one electronic coupon, and providing, in response to the predetermined trigger event, a message for presentation to the consumer via the mobile computing device associated with the consumer, the message configured to direct the consumer to a physical location of a product associated with the at least one electronic coupon. Corresponding systems and methods are also disclosed. | 05-05-2011 |
20120023152 | Methods and Systems for Providing Location-Based Interactive Golf Content for Display by a Mobile Device - An exemplary method includes an interactive golf content computing system detecting a geographic location of a mobile device associated with a golfer while the golfer is playing a golf hole, selecting interactive golf content associated with one or more other golfers who played the golf hole previous to the playing of the golf hole by the golfer in accordance with the detected geographic location, and providing the selected interactive golf content for display by the mobile device. Corresponding methods and systems are also described. | 01-26-2012 |
20120058744 | Mobile Services Access Management Methods and Systems - An exemplary method includes a mobile services access management system maintaining a mobile services access schedule associated with a mobile access device, the mobile services access schedule specifying one or more restricted access time periods during which access by the mobile access device to one or more mobile services requires entry of a predetermined access code, receiving a request to access at least one mobile service within the one or more mobile services during one of the one or more restricted access time periods, receiving entry of a predetermined access code in conjunction with the request, granting the mobile access device access to the at least one mobile service, and providing a notification of the access to a predetermined recipient. Corresponding methods and systems are also disclosed. | 03-08-2012 |
20140057661 | SYSTEMS AND METHODS FOR ENHANCING A USER VISIT TO A SITE PREMISES - Exemplary systems and methods for enhancing a user visit to a site premises are disclosed. An exemplary method includes a mobile device tracking a geographic location of the mobile device, accessing site data associated with a site premises, and providing an interactive user interface configured to enhance a visit of a user of the mobile device to the site premises based on the site data associated with the site premises and the geographic location of the mobile device within the site premises. In certain embodiments, an output may be selected based on the geographic location of the mobile device within the site premises and provided via the interactive user interface for experiencing by the user of the mobile device. Corresponding systems and methods are also disclosed. | 02-27-2014 |
Patent application number | Description | Published |
20090220553 | Composition and Method for Inhibiting, Preventing, or Ameliorating Complications Associated With Ingestion of a Medicinal, Chemical, or Biological Substance or Agent - The application relates, in part, to a therapeutic composition comprising a pharmaceutically active agent and a diarrheagenic agent. | 09-03-2009 |
20130142836 | COMPOSITION AND METHOD FOR INHIBITING, PREVENTING, OR AMELIORATING COMPLICATIONS ASSOCIATED WITH INGESTION OF A MEDICINAL, CHEMICAL, OR BIOLOGICAL SUBSTANCE OR AGENT - The application relates, in part, to a therapeutic composition comprising a pharmaceutically active agent and a diarrheagenic agent. | 06-06-2013 |
20130232103 | METHOD OF CONTINUOUS PREDICTION OF PATIENT SEVERITY OF ILLNESS, MORTALITY, AND LENGTH OF STAY - A method for predicting a patient's outcome variable, such as a probability of mortality/recovery, includes accessing at least one of a plurality past patients' data fields including physiological and/or laboratory data, and a time of stay indicating how long each patient had been under care at the time. An outcome variable estimation algorithm is generated by data mining from a plurality of past patients' physiological and/or laboratory data, corresponding time of stay, and associated outcome variables. A current patient's outcome variable is determined from the current patient's physiological and/or laboratory data, the current time of stay, and the outcome variable estimation algorithm. | 09-05-2013 |
Patent application number | Description | Published |
20110024189 | WELL DRILLING METHODS WITH EVENT DETECTION - A drilling method includes assigning values to behaviors of drilling parameters during a drilling operation; forming multiple parameter signatures, each of the parameter signatures comprising a respective combination of the values; comparing the parameter signatures to multiple event signatures, each of the event signatures being indicative of a respective drilling event; and controlling the drilling operation in response to at least a partial match resulting from comparing the parameter signatures to the event signatures. Another method includes defining an event signature comprising a unique combination of a behavior of each of multiple drilling parameters, the event signature being indicative of a drilling event; accessing data from each of multiple sensors which sense the respective drilling parameters during a drilling operation; determining multiple parameter signature segments from the respective sensed drilling parameters; combining the parameter signature segments, thereby forming a parameter signature; and comparing the parameter signature to the event signature. | 02-03-2011 |
20110303462 | ANNULUS PRESSURE SETPOINT CORRECTION USING REAL TIME PRESSURE WHILE DRILLING MEASUREMENTS - A method of controlling pressure in a wellbore can include determining a real time wellbore pressure Pwb | 12-15-2011 |
20150083401 | DRILLING OPERATION CONTROL USING MULTIPLE CONCURRENT HYDRAULICS MODELS - A control system for drilling a subterranean well can include multiple concurrently running hydraulics models, each of the hydraulics models outputting a pressure setpoint, in real time during a drilling operation. A method of controlling a drilling operation can comprise concurrently running multiple hydraulics models during the drilling operation, and switching between outputs of the multiple hydraulics models to control the drilling operation, the switching being performed during the drilling operation. Another method of controlling a drilling operation can include controlling operation of at least one flow control device, thereby maintaining a pressure at a pressure setpoint, and selecting the pressure setpoint from among outputs of multiple concurrently running hydraulics models. | 03-26-2015 |