Andrew Turner
Andrew Turner, King Of Prussia, PA US
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20080220002 | MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS - Modified fission proteins of transferrin and therapeutic proteins or peptides, preferably antibody variable regions, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor. | 09-11-2008 |
20110091543 | ORAL DELIVERY OF MODIFIED TRANSFERRIN FUSION PROTEINS - Pharmaceutical compositions containing modified fusion proteins of transferrin and therapeutic proteins or peptides with increased serum half-life or increased serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, but does exhibit binding to iron and/or the transferrin receptor. Such fusion proteins may be administered orally. | 04-21-2011 |
20110092677 | MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS - Modified fusion proteins of transferrin and therapeutic proteins or peptides, preferably antibody variable regions, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor. | 04-21-2011 |
Andrew Turner, Durham, NC US
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20100316623 | PHENYLALANINE HYDROXYLASE FUSION PROTEIN AND METHODS FOR TREATING PHENYLKETONURIA - The present invention provides Phenylalanine Hydroxylase (PAH) fusion proteins and pharmaceutical compositions comprising the same, as well as encoding polynucleotides and vectors, and methods for treating hyperphenylalaninemia, including PKU, by enzyme replacement therapy. The fusion proteins have phenylalanine hydroxylase activity when administered: and have an increased half-life or persistence in circulation, as compared to unfused counterparts. The PAH fusion proteins are suitable for enzyme replacement therapy in PKU patients by converting phenylalanine in the circulation to tyrosine, thereby controlling phenylalanine levels. | 12-16-2010 |
20110178017 | MODIFIED VASOACTIVE INTESTINAL PEPTIDES - The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP. | 07-21-2011 |
Andrew Turner, Heighington GB
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20100140240 | POSITIONING MEANS AND METHOD OF USE THEREOF - A positioning device ( | 06-10-2010 |
20130117166 | ASSET MANAGEMENT SYSTEM AND A METHOD FOR ENABLING A PERSON TO FIND A LOCATION WITHIN AN AREA OF SPACE - A method for enabling a person to find a first location within an area of space. The method comprising the steps of dividing an area into a plurality of distinguishable sub-areas, dividing each sub-area into a grid, providing a person with information concerning the distribution of the sub-areas within the area, providing the person with information concerning a first sub-area in which a first location resides within the area, and providing the person with information concerning the grid reference of the first location within the first sub-area. An asset management system is also disclosed that preferably incorporates the above grid reference system. | 05-09-2013 |
Andrew Turner, Morrisville, NC US
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20090275481 | Anchored Transferrin Fusion Protein Libraries - Fusion proteins comprising a transferrin moiety, a stalk moiety, and cell wall linking member and peptide libraries thereof are disclosed. The present invention includes a method of screening peptide libraries displayed in fusion proteins expressed by host cells. The fusion proteins of the present invention include transferrin fusion proteins capable of expression in yeast. | 11-05-2009 |
Andrew Turner, Cheshire GB
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20080269294 | Benzamide Compounds Useful as Histone Deacetylase Inhibitors - The invention concerns benzamide compounds of formula (I), wherein R | 10-30-2008 |
Andrew Turner, Warwickshire GB
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20080220930 | Linear Actuator - A linear actuator includes permanent magnet annuli arranged about an armature core for axial movement in a tubular stator upon energisation of coils arranged in concentric association with the armature. The stator has portions extending radially inwards of the coils and towards one another beneath each coil, which define a spacing between the coil and the armature. The annuli have a substantially radially magnetised structure and the coils are configured for single phase power input. In one embodiment (FIG. | 09-11-2008 |
Andrew Turner, Nashville, TN US
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20110112933 | SYSTEM AND METHOD OF MEDIA DISTRIBUTION MANAGEMENT - There is a media distribution system and method configured to distribute media over a computerized network including a media distribution module configured to selectively permit access to media over a computerized network and including a user interface module. The media distribution system also includes an operational administration module in communication with the media distribution module and configured to facilitate operational management of the media distribution module by selectably altering operational parameters of the media distribution module. In addition, the media distribution system includes a supervisory administration module in communication with the operational administration module and configured to selectably determine operational parameters available to the operational administration module for control. Furthermore, the media distribution system includes a network module in communication with the media distribution module and configured to transfer data over a computerized network. | 05-12-2011 |
Andrew Turner, Macclesfield GB
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20120225907 | BENZAMIDE COMPOUNDS USEFUL AS HISTONE DEACETYLASE INHIBITORS - The invention concerns benzamide compounds of formula (I): compound of formula (I): | 09-06-2012 |
20150376170 | BENZOXAZINONE AMIDES AS MINERALOCORTICOID RECEPTOR MODULATORS - Disclosed are certain derivatives of benzoxazinone amides of formula (I), or pharmaceutically acceptable salts thereof, | 12-31-2015 |
Andrew Turner, Lasalle CA
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20140102387 | VALVE TIMING CONTROL - A valve timing control having a stator body constructed of a plastic material. The stator body has an annular side wall and a front plate which, together, define a plurality of annularly spaced internal cavities within the stator body. A rotor having a plurality of vanes is positioned within the stator body so that one vane is positioned within each cavity. The rotor is movable relative to the stator body between a first and second rotational position. A plurality of threaded metal inserts are embedded within the stator body and used to attach a metal sprocket to the stator body at a position opposed to the front plate. Two of these inserts also receive the impact load from the rotor. | 04-17-2014 |
20150075464 | VALVE TIMING CONTROL - A valve timing control having a stator body constructed of a plastic material. The stator body has an annular side wall and a front plate which, together, define a plurality of annularly spaced internal cavities within the stator body. A rotor having a plurality of vanes is positioned within the stator body so that one vane is positioned within each cavity. The rotor is movable relative to the stator body between a first and second rotational position. A plurality of threaded metal inserts are embedded within the stator body and used to attach a metal sprocket to the stator body at a position opposed to the front plate. Two of these inserts also receive the impact load from the rotor. | 03-19-2015 |
Andrew Turner, Cambridge GB
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20150220465 | SPECULATIVE INTERRUPT SIGNALLING - A data processing system | 08-06-2015 |
Andrew Turner, Mississauga CA
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20150314893 | SPACECRAFT CAPTURE MECHANISM - The present invention provides a capture mechanism for capturing and locking onto the Marman flange located on the exterior surfaces of spacecraft/satellites. The capture mechanism achieves its goal of quickly capturing a client spacecraft by splitting the two basic actions involved into two separate mechanisms. One mechanism performs the quick grasp of the target while the other mechanism rigidises that grasp to ensure that the target is held as firmly as desired. | 11-05-2015 |
Andrew Turner, Durham GB
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20160042615 | EVACUATION ASSISTANCE APPARATUS - An evacuation assistance apparatus for indicating a route within a building or other structure is disclosed. Multiple housings contain laser light line sources for producing a beam of laser light as a linear line. Adjusters are used to alter the laser light line so that the line starts substantially vertically below said housing. The adjusters also allow the line to be directed on to a portion of the wall to highlight an exit doorway. The apparatus is provided as a modular system including multiple sensors making it suitable for installation in many buildings and providing feedback information to prevent or determine the cause of a fire. | 02-11-2016 |