Mitchell, PA
Austin Mitchell, Pittsburgh, PA US
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20110112454 | Patella Alignment Device - One embodiment of the invention is a knee (or elbow) band assembly | 05-12-2011 |
Claire Mitchell, Philadelphia, PA US
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20090220516 | Neuroprotection of retinal ganglion cells - This invention relates to the neuroprotection of the optic nerve and the treatment of glaucoma, more specifically, the invention is directed to a method of preventing, inhibiting, decreasing incidence and suppressing death in ganglion cells by manipulating the P2X | 09-03-2009 |
20090247483 | Method for Treatment of Macular Degeneration - Provided is a method of treating or preventing age-related macular degeneration (AMD) in a patient subject to, or symptomatic of the disease, wherein the method comprises restoring normal lysosomal pH (pH | 10-01-2009 |
20120264708 | Method For Treatment Of Macular Degeneration By Modulating P2Y12 or P2X7 Receptors - Provided is a method of treating or preventing age-related macular degeneration (AMD) in a patient subject to, or symptomatic of the disease, wherein the method comprises restoring normal lysosomal pH (pH | 10-18-2012 |
20140336142 | Method For Treatment Of Macular Degeneration By Modulating P2Y12 or P2X7 Receptors - Provided is a method of treating or preventing age-related macular degeneration (AMD) in a patient subject to, or symptomatic of the disease, wherein the method comprises restoring normal lysosomal pH (pH | 11-13-2014 |
Claire H. Mitchell, Philadelphia, PA US
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20130338145 | Method for Mediating Dopamine Receptor-Driven Reacidification of Lysosomal pH - Provided is a method of treating or preventing age-related macular degeneration (AMD) or Stargardt's disease in a patient subject to, or symptomatic of the disease, whereby normal lysosomal pH (pH | 12-19-2013 |
David B. Mitchell, Yardley, PA US
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20110290722 | ACTIVATED SLUDGE PROCESS IN WASTEWATER TREATMENT - The present disclosure relates to methods of treating highly contaminated wastewater using waste activated sludge as an adsorbent. | 12-01-2011 |
David T. Mitchell, Newtown, PA US
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20090214762 | SPATIOTEMPORAL AND GEOMETRIC OPTIMIZATION OF SENSOR ARRAYS FOR DETECTING ANALYTES IN FLUIDS - Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed. | 08-27-2009 |
Dora P. Mitchell, Langhorne, PA US
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20110236325 | METHODS TO TREAT OR PREVENT A SKIN CONDITION USING A NELL1 PEPTIDE - The described invention provides methods and compositions utilizing a NELL1 peptide or nucleic acid encoding a NELL1 peptide for treating or preventing a skin condition. The methods include treating or preventing manifestations of aging in human skin, repairing damage to skin, and preventing skin scarring. Methods are also provided for assaying a test peptide for NELL1 activity. | 09-29-2011 |
George N. Mitchell, Mars, PA US
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20090178590 | METHOD FOR REINFORCING CONCRETE - A method for making a multi-stage cementitious material with high-temperature reinforcing fibers | 07-16-2009 |
Gina Mitchell, Columbia, PA US
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20140284185 | WOVEN WIRE CONVEYOR BELT AND A METHOD OF FORMING THE SAME - A woven wire conveyor belt having a plurality of spiral wires and a plurality of connecting wires operably associated with the plurality of spiral wires to form a conveying surface with a plurality of openings formed therein. Each of the plurality of spiral wires has a first side wall and a second side wall that are substantially flat. The connecting wires can be crimped or straight wires. The spiral wires can be left spiral wires, right spiral wires or a combination of left and right spiral wires. The spiral wires and the connecting wires are preferably formed from round wire. Preferably, the woven wire conveyor belt is an endless belt. The conveyor belt can be a balanced weave wire belt, a double weave wire belt, a rod reinforced weave wire belt, a chevron weave wire belt, a double balance weave wire belt, and a single weave wire belt. | 09-25-2014 |
Glenn Michael Mitchell, Sellersville, PA US
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20100041234 | Process For Restoring Dielectric Properties - A method for preparing an interlayer dielectric to minimize damage to the interlayer's dielectric properties, the method comprising the steps of: depositing a layer of a silicon-containing dielectric material onto a substrate, wherein the layer has a first dielectric constant and wherein the layer has at least one surface; providing an etched pattern in the layer by a method that includes at least one etch process and exposure to a wet chemical composition to provide an etched layer, wherein the etched layer has a second dielectric constant, and wherein the wet chemical composition contributes from 0 to 40% of the second dielectric constant; contacting the at least one surface of the layer with a silicon-containing fluid; optionally removing a first portion of the silicon-containing fluid such that a second portion of the silicon-containing fluid remains in contact with the at least one surface of the layer; and exposing the at least one surface of the layer to UV radiation and thermal energy, wherein the layer has a third dielectric constant that is restored to a value that is at least 90% restored relative to the second dielectric constant. | 02-18-2010 |
20100055921 | Selective Etching of Silicon Dioxide Compositions - A process for selectively etching a material comprising SiO | 03-04-2010 |
Helen J. Mitchell, Richboro, PA US
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20090275515 | 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS - Compounds of structural formula (I) are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HFV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents. | 11-05-2009 |
20100267633 | N-(4-Oxo-3,4-Dihydroquinazolin-2Yl) Butanamides as Androgen Receptor Modulators - The invention relates to substituted N-(4-oxo-3,4-dihydroquinazolin-2-yl)butanamid derivatives which modulate androgen receptors to treat conditions such as: osteoporosis, peridontal disease, bone fracture, frailty, and sarcopenia. | 10-21-2010 |
20110003797 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE CARBOXAMIDES AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention is directed to hexahydrocyclopentyl[f]imidazole carboxamides and derivatives thereof as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 01-06-2011 |
20110105440 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE SULFONAMIDES AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention is directed to hexahydrocyclopentylf]indazole carboxamides and derivatives thereof as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 05-05-2011 |
20120095055 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE 5-HYDROXYMETHYL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention encompasses compounds of Formula (I): or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 04-19-2012 |
20120122899 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS - The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. | 05-17-2012 |
20120122900 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS - The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. | 05-17-2012 |
20120172397 | HEXAHYDROCYCLOPENTA[f]INDAZOLE 5-YL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention encompasses compounds of Formula (I) or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 07-05-2012 |
20120214846 | HEXAHYDROCYCLOPENTYL[F]INDAZOLE PYRIDYL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS - The present invention encompasses compounds of Formula (I): or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 08-23-2012 |
20130231358 | PIPERIDINONE CARBOXAMIDE INDANE CGRP RECEPTOR ANTAGONISTS - The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. | 09-05-2013 |
20140005214 | PIPERIDINONE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS | 01-02-2014 |
20150031716 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS - The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. | 01-29-2015 |
Jaime Tadeo Mitchell, Bethlehem, PA US
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20110054924 | PATIENT COMMUNICATIONS DEVICE - A handheld patient communication device ( | 03-03-2011 |
John William Mitchell, Allentown, PA US
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20120149794 | N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes - The present invention provides compounds produced by the reaction of glycidyl ethers and glycidyl esters with ether compounds including N,N,N′-trimethyl-bis-(aminoethyl)ether. N,N,N′-trimethyl-bis-(aminoethyl)ether and its derivatives can be used as polyurethane catalysts. | 06-14-2012 |
Kevin Mitchell, Downingtown, PA US
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20100124013 | Laptop computer carrying case that transforms into a desk top - A laptop computer carrying case transforms into a desktop for use of a laptop or similar electronic device having a keyboard and a hingeably openable display. The laptop key board is held by bands in the lower portion of the case and the display is held in the top section of the case. Hinge structures are provided on the left and right sidewalls of the bottom section of the case. When the hinge structures are pivotally angularly separated, the bottom section containing the keyboard will be substantially horizontal enabling use of the laptop in a standing or mobile position. When the laptop is not being used, the case may be closed and the hinge structures closed with the laptop being carried by the strap over the shoulder. The hinge structure is provided with structure for limiting the amount by which the arms of the hinge may be pivotally angularly separated thereby providing stability to the laptop case in the desk top position. Detent means is provided to hold the arms of the hinge structure in aligned position when the case is being used to carry the laptop. | 05-20-2010 |
Marilyn A. Mitchell, Philadelphia, PA US
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20080242623 | Microutrophin and Uses Thereof - A microutrophin containing a utrophin having internal deletions (relative to a native utrophin) in the hinge regions and a C-terminal deletion is provided. Also provided are vectors and compositions useful for delivering the microutrophin for the treatment of muscular disorders, including Duchenne Muscular Dystrophy. | 10-02-2008 |
Nicholas C. Mitchell, Gibsonia, PA US
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20090178590 | METHOD FOR REINFORCING CONCRETE - A method for making a multi-stage cementitious material with high-temperature reinforcing fibers | 07-16-2009 |
Paul Andrew Mitchell, Lancaster, PA US
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20080197273 | Light Detection Apparatus - A light detection apparatus is described. The apparatus includes a photomultiplier tube having a window for receiving light incident thereon. A photocathode is affixed to an inner surface of the window in a known manner. The apparatus further includes an optical fiber and a means for coupling the optical fiber to the window of said photomultiplier tube so that light can be introduced into the window at an angle that results in total internal reflection of the light. The coupling means may be embodied as a fiber optic terminal connector. Alternatively, the coupling means may include a prism affixed to the outside surface of the window. | 08-21-2008 |
Rebekah J. Mitchell, Milton, PA US
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20110109116 | Ice Guard - The Ice Guard is a specially designed protective covering configured specifically to encompass the entire front windshield or rear window of a vehicle, thus protecting these areas from the elements. Generally rectangular in shape and gently contoured for a custom fit, the Ice Guard is designed to encompass the windshield completely, thus effectively preventing the accumulation of frost, ice or snow. The Ice Guard is produced in a range of sizes appropriate for the various makes and model vehicles on the market. | 05-12-2011 |
Slade Mitchell, Chester Springs, PA US
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20150349883 | LIGHT BASED LOCATION SYSTEM - Aspects of the disclosure relate to a light source based location and operation system. A computing device may detect an encoded light signal containing an identifier from a light source at a location. The encoded light signal can be decoded to obtain the identifier, and a request for information based on the identifier can be transmitted in response to decoding the identifier. Information associated with the identifier may be received in response to the request for information including location information corresponding to the location of the light source. The location information may be used to provide additional information to the user or enable a user to control devices based on the location information. | 12-03-2015 |
Stew Mitchell, Old Forge, PA US
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20120028001 | Thermoformed or Molded Partition - A partition panel is made of two overlaying sheets of high density polyethylene or other plastic material which have been bonded together around a perimeter and at selected regions such that the partition panel contains bonded regions where the two sheets are bonded together and hollow regions where the two sheets are spaced apart from one another. The partition panel is preferably made by thermoforming. | 02-02-2012 |
Wesley Mitchell, Glenshaw, PA US
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20130147131 | Rotary Stage With Integrated Collet Closer Assembly - A rotary stage having an integrated collet closure assembly includes: an actuating piston positioned in a piston housing; a drawbar configured to be moved axially depending on the position of the actuating piston to open and close the collet closure assembly, and rotationally by movement of a rotating shaft of the rotary stage; and a pair of thrust bearings provided between the actuating piston and the drawbar. The pair of thrust bearings acts as an interface between the actuating piston and the drawbar such that the drawbar rotates freely and the actuating piston and the piston housing remain stationary in a rotary direction. | 06-13-2013 |
William Brian Mitchell, Erie, PA US
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20140169869 | Quick Assembling Furniture - The invention is directed to furniture such as of floor independently standing or wall mounted furniture, cabinetry, containers, boxes that can be lightweight, modular, easily assembled and disassembled. | 06-19-2014 |