Patent application number | Description | Published |
20090202469 | Detection of inflammatory disease and composition for preventing or treatment of inflammatory disease - A novel method for detection of an inflammatory disease and a novel composition for prevention or treatment of an inflammatory disease are provided. The method for detection of an inflammatory disease comprises using RANKL and/or OPG as a marker in a biological sample. The composition for prevention or treatment of an inflammatory disease comprises RANKL and/or M-CSF as an active ingredient. | 08-13-2009 |
20100086489 | OSTEOPENIA ANIMAL MODEL - The present invention provides a method for producing an osteopenia animal model by RANKL administration and an osteopenia animal model. | 04-08-2010 |
20100105612 | AGENT CONTAINING FUSED PROTEIN OF SOLUBLE RANKL WITH EPITOPE TAG - The present invention provides a reagent containing a fused protein of RANKL with an epitope tag that has improved effects of differentiating and activating osteoclasts and improved preservation stability compared with the case of using RANKL alone, and an agent for differentiating and activating osteoclasts that can be used in vitro or in vivo, containing, as an active ingredient, a fused protein of soluble RANKL with an epitope tag peptide. | 04-29-2010 |
20100260680 | NOVEL BONE MASS INCREASING AGENT - The present invention provides an osteogenesis enhancer comprising a molecule capable of acting on RANKL that enhances differentiation, proliferation, maturation, or calcification of osteoblasts or cells capable of differentiating into osteoblasts. A pharmaceutical composition for treatment or prevention of bone metabolism diseases associated with osteopenia, which comprising, as an active ingredient, a compound that acts on RANKL located on osteoblasts or cells capable of differentiating into osteoblasts and promotes differentiation, proliferation, maturation, or calcification of osteoblasts or cells capable of differentiating into osteoblasts is provided. | 10-14-2010 |
20110117645 | METHOD FOR PROLIFERATION OF PLURIPOTENT STEM CELLS - For efficient proliferation of pluripotent stem cells in a system free from any animal-derived material such as feeder cells or serum, the present invention provides a method for proliferation of pluripotent stem cells, which comprises culturing the pluripotent stem cells in a medium free from both feeder cells and serum in a system containing laminin-5. | 05-19-2011 |
20110177069 | NOVEL INDUCER OF CHONDROCYTE PROLIFERATION AND DIFFERENTIATION - This invention provides a method for administration of an effective amount of RANKL-binding molecules that act on prechondrocytes and/or mesenchymal stem cells, accelerate cartilage differentiation, proliferation, and maturation of such cells, enhance chondrocyte differentiation, and induce chondrocyte proliferation to induce chondrocyte proliferation and differentiation or increase cartilage matrix production and a pharmaceutical composition used for inducing chondrocyte proliferation and differentiation or increasing cartilage matrix production. The pharmaceutical composition used for treatment or prevention of a chondropathies comprises, as an active ingredient, a compound that acts on prechondrocytes and/or mesenchymal stem cells and induces at least one of the following: (a) acceleration of prechondrocyte and/or mesenchymal stem cell differentiation; (b) acceleration of prechondrocyte and/or mesenchymal stem cell proliferation; (c) acceleration of prechondrocyte and/or mesenchymal stem cell maturation; (d) enhancement of chondrocyte differentiation; (e) chondrocyte proliferation; and (f) increased production of the cartilage matrix. | 07-21-2011 |
Patent application number | Description | Published |
20090026865 | Motor and Its Rotor and Magnetic Core for Rotor - A first non-magnetic portion, a second non-magnetic portion, and a third non-magnetic portion are arranged around an axis, from an end toward the center of a permanent magnet burying hole. A fourth non-magnetic portion is further provided between the second non-magnetic portion and the third non-magnetic portion. Angles around the axis are determined as follows with reference to a position between permanent magnet burying holes. The position between the first non-magnetic portion and the second non-magnetic portion is expressed by a first angle. The position between the third non-magnetic portion and the fourth non-magnetic portion is expressed by a second angle, and the second angle is twice the first angle. The end of the third non-magnetic portion located closer to the pole center is expressed by a third angle. The first angle and the third angle are values obtained by dividing 360 degrees respectively by a value that is seven times, and a value that is three times, the number of the permanent magnet burying holes. | 01-29-2009 |
20100119378 | ROTARY COMPRESSOR - A rotary compressor includes a compression mechanism, an electric motor and a controller. The compression mechanism includes a piston and a cylinder having two cylinder chambers. The electric motor is configured to change volumes of the cylinder chambers by eccentrically moving the cylinder and the piston relative to each other. The controller is configured to change an output torque of the electric motor in accordance with a variation in a load torque of the compression mechanism in one turn of rotation. | 05-13-2010 |
20100135830 | ROTATING ELECTRIC MACHINE AND COMPRESSOR - A rotating electric machine for a compressor includes a case, a plurality of teeth, coils and insulating films. The teeth are circumferentially arranged around a predetermined axis forming a center of the teeth. Each tooth has a first end disposed radially at an opposite side thereof from the predetermined axis. The a back yoke has a circular outer periphery, and a cylindrical inner periphery connecting the first ends of the teeth. The outer periphery has a plurality of concave parts opening radially inwardly toward the teeth at positions overlapping with the teeth as viewed radially. A minimum distance measured from an exposure surface of each tooth to the concave part overlapping therewith is smaller than a radial width of the back yoke at a portion where the concave parts are not provided. The exposure surfaces extend radially inwardly of the inner periphery. | 06-03-2010 |
20120013210 | BUS RING, AND FIXING STRUCTURE THEREOF - There is provided a bus ring attached to a stator having a plurality of stator teeth aligned in a circumferential direction and a winding wound around each of the stator teeth along an end face of the stator of a rotary electrical machine in an axial direction, and the bus ring is made by curving a conductive wire in an arc shape with a diameter smaller than that of the stator, and staple-shaped bent portions are formed at the conductive wire and the winding is connected to the bent portions. There is also provided a fixing structure of the bus ring configured such that an insulator is interposed between each of the stator teeth and the winding protruding in the axial direction from the end face of the stator to enter inside the conductive wire of the bus ring. | 01-19-2012 |
20140021820 | ROTOR AND ROTARY ELECTRIC MACHINE USING THE SAME - A first rotor core including a plurality of gaps penetrating through the first rotor core along an axial direction is provided. A second rotor core being in contact with an axial end of the first rotor core and having a plurality of magnet-housing slots facing the gaps is also provided. The gaps have a magnetic resistance lower than that of the magnet-housing slots. | 01-23-2014 |