Schnell, CH
Alexander Schnell, Baden CH
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20090255117 | GAS TURBINE HOT GAS COMPONENT REPAIR METHOD - A gas turbine engine hot gas component repair method for defects that do not extend through the thickness of the component is provided. First defects are removed by machining a cavity in the surface of a component. Coupons, fittable within the cavities are manufactured, are for example coated with brazing medium on an inner surface and then joined to the component by joining means such as laser metal forming. The joint holds the coupon during later heat treatment, thereby eliminating a need for holding aids. Before heat treatment, a further brazing medium can be applied to the surface of the coupon overlapping onto the component. A single heat treatment, brazing the coupon to the component and, brazing the brazing medium to the outer surface of the coupon can, then be used to complete the repair. | 10-15-2009 |
20110048018 | COMBUSTION DEVICE OF A GAS TURBINE - A combustion device for a gas turbine that includes a portion having first and second walls that defines an inside of the combustion device, a zone between the first and second walls and an outside of the combustion device. A plurality of first passages connect the inside of the combustion device to the zone between the first and second walls and a plurality of second passages connect the zone between the first and second walls to the outside of the combustion device. A plurality of chambers are defined within the zone between the first and second walls, each chamber being connected with one first passage and at least one second passage. Each chamber defining a Helmholtz damper. | 03-03-2011 |
20110103967 | ABRASIVE SINGLE-CRYSTAL TURBINE BLADE - A turbine blade for a turbine rotor, is provided having a single-crystal basic body which has a blade tip and extends in the radial direction. The turbine blade includes at least one oxidation-resistant intermediate coating, which is applied by laser metal forming and is epitaxially bonded to the basic body, is arranged on the radially outer blade tip, and in that an at least single-layer, wear-resistant and oxidation-resistant coating, which is applied by laser metal forming and consists of oxidation-resistant binder material and abrasive particles embedded therein, is arranged on at least certain regions of said epitaxial intermediate coating. | 05-05-2011 |
20110171039 | BLADE ARRANGEMENT OF A GAS TURBINE - A blade arrangement of a gas turbine, with at least one blade which in the radial direction projects into a hot gas passage arranged concentrically to an axis, and terminates in a blade tip which with a clearance lies opposite a heat shield which delimits the hot gas passage. The blade and the heat shield are movable in relation to each other in the circumferential direction, and the blade tip and the heat shield are covered with coatings, which enable a directed cutting of the blade tip into the heat shield. By such a blade arrangement, a reduction of the clearance as a result of cutting in is simply achieved by the heat shield having a porous thermal barrier coating as an outer, abradable coating, and by the blade tip being provided with a homogenous, metallic cover coating. | 07-14-2011 |
20120063911 | DUAL BRAZING ALLOY ELEMENT, PROCESS FOR PRODUCING IT AND USES THEREOF - A dual brazing alloy element for a materially integral connection of a ceramic surface to a metallic surface includes a first layer having a Ni-based brazing alloy with a Ni content of at least 50% by weight and having at least one component configured to lower a melting point of the Ni-based brazing alloy selected from the group consisting of Si, B, Mn, Sn and Ge. A second layer includes an active brazing alloy material having a total content of 1-15% by weight of at least one active element selected from the group consisting of Ti, Hf, Zr and V. | 03-15-2012 |
Christian Schnell, Basel CH
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20100280094 | COMPOSITIONS AND METHODS TO TREAT MUSCULAR & CARDIOVASCULAR DISORDERS - The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or double stranded oligonucleotides such as dsRNA) and their use in the treatment of muscular and cardiovascular disorders resulting from dysregulation of mir-208-2. | 11-04-2010 |
20120114744 | COMPOSITIONS AND METHODS TO TREAT MUSCULAR & CARDIOVASCULAR DISORDERS - The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or double stranded oligonucleotides such as dsRNA) and their use in the treatment of muscular and cardiovascular disorders resulting from dysregulation of mir-208-2. | 05-10-2012 |
Christian Rene Schnell, Basel CH
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20120041052 | Compositions and Methods to Treat Muscular & Cardiovascular Disorders - The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or double stranded oligonucleotides such as dsRNA) and their use in the treatment of muscular and cardiovascular disorders resulting from dysregulation of mir-208-2. | 02-16-2012 |
20130230923 | Short Interfering Ribonucleic Acid (siRNA) for Oral Administration - Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification. | 09-05-2013 |
Lisa Schnell, Zurich CH
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20080317741 | Biomarkers For Anti-Nogo-A Antibody Treatment in Spinal Cord Injury - This disclosure of this invention confirms, at the level of gene expression, the injured spinal cord and motor cortex as the primary sites of action of the anti-Nogo-A antibody treatment applied intrathecally. The disclosure further provides methods for predicting the response of a subject to a medicament comprising an anti-Nogo-A antibody. | 12-25-2008 |
20110059110 | ANTIBODY (11C7) ANTI NOGO-A AND ITS PHARMACEUTICAL USE - This invention relates to molecules, such as for example monoclonal antibodies or Fab fragments thereof, which are capable of binding to the human NogoA polypeptide or human NiG or human NiG- or human NogoA_623-640 with a dissociation constant, 1000 nM; polynucleotides encoding such a binding molecule; an expression vector comprising such polynucleotides; the use of such a binding molecule in the treatment of nerve repair, a pharmaceutical composition comprising such a binding molecule; and to a method of treatment of diseases associated with nerve repair. | 03-10-2011 |
Marc Schnell, Zuerich CH
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20120242335 | Cryogenic probehead cooler in a nuclear magnetic resonance apparatus - An NMR (nuclear magnetic resonance) apparatus has a magnet system disposed in a cryostat ( | 09-27-2012 |
Marc A. Schnell, Zuerich CH
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20140283530 | Method for cryogenic cooling of an NMR detection system with the assistance of a container filled with a cryogenic fluid - A method for the transmission/reception of RF signals for NMR measurements uses a heat exchanger ( | 09-25-2014 |
Marc A. Schnell, Zurich CH
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20110100027 | Cooling device for cryogenic cooling of an NMR detection system with the assistance of a container filled with a cryogenic fluid - A cryo probe head for the transmission/reception of RF signals for NMR measurements with a heat exchanger ( | 05-05-2011 |
Pascal Schnell, Baerschwil CH
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20120234568 | Portable Machine Tool Switching Unit - A portable machine tool switching unit includes a turning knob unit, which has a coupling unit that can be rotatably driven for coupling to at least one switching element, and further includes at least one energy storage element provided for storing switching energy in the case of a preselection. The energy storage element is integrated in the turning knob unit. | 09-20-2012 |
20130233447 | Bearing Device - A bearing device of a portable power tool, in particular a router, has at least one main body unit. The main body unit is formed as a corner guiding unit and has a bearing surface and a lead-through opening. The bearing surface is configured to bear on a workpiece. The lead-through opening is configured to receive an insert tool configured to perform work on a workpiece. | 09-12-2013 |
20130240087 | PORTABLE POWER TOOL - A portable power tool includes at least one seating unit configured to seat on a workpiece, at least one housing unit mounted so as to be movable relative to the seating unit, and at least one movement delimitation unit that has at least one movement delimitation element configured to set a length of a movement travel of the housing unit relative to the seating unit. The portable power tool further includes at least one decoupling unit configured, in at least one operating state, to decouple the movement delimitation unit from a movement of the housing unit when the movement delimitation element is in a fixed state. The decoupling of the movement delimination unit occuring at least in the case of a movement of the housing unit in the direction of the seating unit. | 09-19-2013 |
20130240088 | PORTABLE POWER TOOL - A portable power tool includes at least one drive unit configured to drive an insert tool, at least one housing unit in which the drive unit is disposed, and at least one marking unit configured to mark a relative position of a drive axis of the drive unit on a workpiece to be machined. The the marking unit is disposed on the housing unit. | 09-19-2013 |
Raffael Schnell, Lenzburg CH
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20100276727 | REVERSE-CONDUCTING SEMICONDUCTOR DEVICE - A reverse-conducting semiconductor device is disclosed with an electrically active region, which includes a freewheeling diode and an insulated gate bipolar transistor on a common wafer. Part of the wafer forms a base layer with a base layer thickness. A first layer of a first conductivity type with at least one first region and a second layer of a second conductivity type with at least one second and third region are alternately arranged on the collector side. Each region has a region area with a region width surrounded by a region border. The RC-IGBT can be configured such that the following exemplary geometrical rules are fulfilled: each third region area is an area, in which any two first regions have a distance bigger (i.e., larger) than two times the base layer thickness; the at least one second region is that part of the second layer, which is not the at least one third region; the at least one third region is arranged in the central part of the active region in such a way that there is a minimum distance between the third region border to the active region border of at least once the base layer thickness; the sum of the areas of the at least one third region is between 10 and 30% of the active region; and each first region width is smaller than the base layer thickness. | 11-04-2010 |
Raffael Schnell, Seon CH
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20120199954 | SEMICONDUCTOR DEVICE - A semiconductor device which provides a small and simple design with efficient cooling. A first electrically conducting cooling element is in contact with first electrodes of semiconductor elements for forwarding a heat load from the semiconductor elements and for electrically connecting the first electrodes of the semiconductor elements to an external apparatus. A second electrically conducting cooling element is in contact with second electrodes of the semiconductor elements for forwarding a heat load from the semiconductor elements and for electrically connecting the second electrodes of the semiconductor elements to an external apparatus. The semiconductor device includes an interface which is electrically connected to gates of the semiconductor elements for external control of respective states of the semiconductor elements. | 08-09-2012 |
20130106469 | CONTROL CONTACT DRIVING SYSTEM | 05-02-2013 |
20140320178 | INTELLIGENT GATE DRIVER FOR IGBT - A reverse-conducting insulated gate bipolar transistor, particularly a bi-mode insulated gate transistor, is controlled by responding to an ON command by applying high-level gate voltage for a first period, during which a current is fed into a connection point, from which it flows either through the RC-IGBT or along a different path. Based hereon, it is determined whether the RC-IGBT conducts in its forward/IGBT or reverse/diode mode, and the RC-IGBT is either driven at high or low gate voltage. Subsequent conduction mode changes may be monitored in the same way, and the gate voltage may be adjusted accordingly. A special turn-off procedure may be applied in response to an OFF command in cases where the RC-IGBT conducts in the reverse mode, wherein a high-level pulse is applied for a second period before the gate voltage goes down to turn-off level. | 10-30-2014 |
Thomas Schnell, Muttenz CH
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20130087637 | SANITARY INSERTION UNIT AND SHOWER FITTING HAVING A SANITARY INSERTION UNIT - A sanitary insertion unit which has a sealing ring ( | 04-11-2013 |