Shields, CA
Barton Shields, Escondido, CA US
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20140006555 | REMOTE TRANSFER OF ELECTRONIC IMAGES TO A VEHICLE | 01-02-2014 |
David E. Shields, San Lorenzo, CA US
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20090247452 | PHARMACEUTICAL FORMULATIONS FOR REDUCING PAIN - The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 10-01-2009 |
20110021436 | METHOD FOR REDUCING PAIN WITH ZICONOTIDE AND MORPHINE - The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 01-27-2011 |
20110021437 | METHOD FOR REDUCING PAIN WITH ZICONOTIDE AND BACLOFEN - The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 01-27-2011 |
20120003290 | METHOD FOR REDUCING PAIN - The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 01-05-2012 |
20130096066 | PHARMACEUTICAL FORMULATION FOR REDUCING PAIN - The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 04-18-2013 |
20130225499 | METHOD FOR ADMINISTERING OMEGA-CONOPEPTIDE - The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 08-29-2013 |
20140107038 | METHOD FOR ADMINISTERING OMEGA-CONOPEPTIDE - The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl 1, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 04-17-2014 |
20140371153 | METHOD FOR ADMINISTERING OMEGA-CONOPEPTIDE - The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl 1, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 12-18-2014 |
20150374787 | METHOD FOR ADMINISTERING OMEGA-CONOPEPTIDE - The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl 1, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil. | 12-31-2015 |
Derek Shields, Los Angeles, CA US
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20080313042 | USER DRIVEN SYSTEM FOR ENABLING ASSOCIATIVE ENDORSEMENT AND DISTRIBUTION OF BRANDING CAPSULES - Building brand awareness that enables users to personally endorse and drive branded messages to a plurality of targets that have a high likelihood of being receptive to the message and associated branding. To ensure that the brand messaging is kept consistent with the desires of the advertiser a repository of brand capsules is available for driving users to select from. To propagate a brand capsule into the community the driving user selects the brand capsule from the repository and associates it with an anticipated event the driving user wishes to associate with the chosen brand. After identification of the targets the brand capsule is forwarded to the targets via a transport mechanism appropriate for carrying the encapsulated imagery and data to the target users. By sending out the brand capsule the driving user implicitly or explicitly endorses the brand by associating it with a personal event, message or request. | 12-18-2008 |
Gary L. Shields, Rancho Santa Fe, CA US
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20110118834 | FLUIDIC INTRAOCULAR LENS SYSTEMS AND METHODS - The present invention relates to a fluidic intraocular lens inserted into a capsular bag of an eye to replace a crystalline lens. The fluidic intraocular lens may be shaped by elastic membranes bonded to a support ring. The space inside the device may be filled with optically transparent fluid or gel having an index of refraction greater than the index of vitreous humor. The device may be such designed so that the focusing power of the lens can be changed by the deformation of the capsular bag, which may be subsequently controlled by a ciliary muscle. | 05-19-2011 |
James Preston Shields, Wildomar, CA US
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20130058594 | Localized Dust Containment Apparatus - A portable, removable dust containment system is disclosed for capturing and containing the dust generated by work performed on a work surface, such as the wall or ceiling inside a room. The device includes a transparent plastic bag with a first large opening at one end, and with the bag tapering to a smaller second opening at a second end. The device is removably affixed by an adhesive onto a wall surface, with the perimeter of the first opening surrounding an area where work is to be done on the wall. The user extends his or her hand through the second opening and closes the second opening. Any dust generated by the work is captured and contained within the bag and can be discarded when the bag is removed from the wall. | 03-07-2013 |
Janice M. Shields, San Marcos, CA US
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20120283597 | Device for Collecting a Urine Sample - A device and method for collecting a urine sample from a neonate is provided. The device is attached to the neonate shortly after birth and removed after the neonate produces a urine sample. An interior shell and an exterior shell form the device, and an absorbent material is located inside the interior shell to absorb the urine sample. The interior shell and the exterior shell are connected by a hinge and are initially in a nesting position, with the exterior shell on top of the interior shell. After the urine sample is absorbed by the absorbent material, the exterior shell is rotated around an axis defined by the hinge to contact and compress the absorbent material to release the urine sample for collection. | 11-08-2012 |
20150016809 | Warming Bag for Neonate Nutritional Liquid - A sterilized system component is disclosed for holding a container of neonate nutritional liquid during a warming of the nutritional liquid. Structurally, the system component includes a pouch-shaped receptacle having a water-filled enclosure. The receptacle includes an outer bag and an inner bag. The inner bag is conformed to be received into the outer bag with the open end of the inner bag affixed to the periphery of the outer bag opening to create a permanent, fluid-tight seal. This permanent seal then creates an enclosed fluid chamber between the inner bag and the outer bag that can be filled with warm water through a fluid port that is provided in the outer bag. Prior to the warming procedure, both the receptacle and the water that is used need are sterilized using ultraviolet radiation from a germicidal lamp. | 01-15-2015 |
20150050398 | UV Adapter for Preparation of Neonate Nutritional Fluid - A system for preparing a nutritional liquid for ingestion by a neonate is disclosed. The system includes a receptacle for sterilizing water for use in warming the nutritional liquid. A sterilizer having an ultraviolet (UV) light source is engaged with the receptacle, and a fluid pump is provided to pump sterilized water from the receptacle and into a sleeve compartment of a warming bag. The sleeve compartment surrounds an interior pocket that is dimensioned to receive a container that is filled with the nutritional liquid. The system also includes a heater/vibrator having a reservoir and a heating element. The reservoir is dimensioned to receive the warming bag and liquid-filled container. When the heating element is activated, heat is conducted from the heating element to the reservoir, from the reservoir to the water, and from the water to the nutritional liquid in the liquid-filled container. | 02-19-2015 |
Jason Shields, San Diego, CA US
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20110097145 | CHASSIS MOUNT - A mounting assembly includes a chassis for receiving electronic components. First and second wedge members are coupled to a base panel of the chassis and each include an angled surface oriented towards a common direction. A mounting plate is adapted to be secured to a supporting surface, including first and second wedge receiving elements including complementary angled surfaces adapted to receive to the angled surfaces of the first and second wedge members. An intermediate member couples the first and second wedge receiving elements to maintain a fixed distance therebetween, and clamping structure is accessible from at least one face panel. The clamping structure is adapted to move the first and second wedge members towards the respective first and second wedge receiving elements such that engagement of the respective angled surfaces with the respective complementary angled surfaces applies a clamping force to the first and second wedge members. | 04-28-2011 |
Jason Robert Shields, Pleasanton, CA US
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20160033763 | PROTECTED LENS COVER PLATE FOR AN OPTICAL METROLOGY DEVICE - A cover plate or lens for an optical metrology device that is positioned under a wafer during measurement is protected with a purge device. The purge device may include a ring that extends around a periphery of the cover plate or lens. The ring includes a plurality of apertures through which a purge gas or air is expelled over the surface of the cover plate or lens. Additionally or alternatively, one or more heating elements may be provided that extend around the periphery of the cover plate or lens. The heating elements heat the cover plate above a dewpoint temperature of contaminant vapor. A heat sensor may be used to monitor the temperature of the cover plate to control the heating elements and/or to compensate for optical changes of the cover plate caused by heating during measurement of a wafer. | 02-04-2016 |
Jeffery A. Shields, Sunnyvale, CA US
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20120038051 | BURIED SILICIDE LOCAL INTERCONNECT WITH SIDEWALL SPACERS AND METHOD FOR MAKING THE SAME - A buried local interconnect and method of forming the same counterdopes a region of a doped substrate to form a counterdoped isolation region. A hardmask is formed and patterned on the doped substrate, with a recess being etched through the patterned hardmask into the counterdoped region. Dielectric spacers are formed on the sidewalls of the recess, with a portion of the bottom of the recess being exposed. A metal is then deposited in the recess and reacted to form silicide at the bottom of the recess. The recess is filled with fill material, which is polished. The hardmask is then removed to form a silicide buried local interconnect. | 02-16-2012 |
20120276706 | DAMASCENE METAL-INSULATOR-METAL (MIM) DEVICE IMPROVED SCALEABILITY - A present method of fabricating a memory device includes the steps of providing a dielectric layer;, providing an opening in the dielectric layer, providing a first conductive body in the opening, providing a switching body in the opening, the first conductive body and switching body Filling the opening, and providing a second conductive body over the switching body. In an alternate embodiment, a second dielectric layer is provided over the first-mentioned dielectric layer, and the switching body is provided in an opening in the second dielectric layer. | 11-01-2012 |
Jeffrey Shields, Sunnyvale, CA US
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20130062587 | Resistive Switching Devices Having Alloyed Electrodes And Methods of Formation Thereof - In accordance with an embodiment of the present invention, a resistive switching device comprises a bottom electrode, a switching layer disposed over the bottom electrode, and a top electrode disposed over the switching layer. The top electrode comprises an alloy of a memory metal and an alloying element. The top electrode provides a source of the memory metal. The memory metal is configured to change a state of the switching layer. | 03-14-2013 |
20130214234 | Resistive Switching Devices and Methods of Formation Thereof - In accordance with an embodiment of the present invention, a resistive switching device includes an opening disposed within a first dielectric layer, a conductive barrier layer disposed on sidewalls of the opening, a fill material including an inert material filling the opening. A solid electrolyte layer is disposed over the opening. The solid electrolyte contacts the fill material but not the conductive barrier layer. A top electrode is disposed over the solid electrolyte. | 08-22-2013 |
Jeffrey A. Shields, Sunnyvale, CA US
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20090163018 | Method to prevent alloy formation when forming layered metal oxides by metal oxidation - The present method of fabricating a resistive memory device includes the steps of providing a first electrode, oxidizing a portion of the first electrode with an oxidizing agent, providing a metal body on the oxidized portion of the first electrode, oxidizing the entire metal body with an oxidizing agent, and providing a second electrode on the oxidized metal body. | 06-25-2009 |
Jeffrey Allan Shields, Sunnyvale, CA US
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20130285004 | SOLID ELECTROLYTE MEMORY ELEMENTS WITH ELECTRODE INTERFACE FOR IMPROVED PERFORMANCE - A memory element can include a first electrode; a second electrode; and a memory material programmable between different resistance states, the memory material disposed between the first electrode and the second electrode and comprising a solid electrolyte with at least one modifier element formed therein; wherein the first electrode is an anode electrode that includes an anode element that is ion conductible in the solid electrolyte, the anode element being different than the modifier element. | 10-31-2013 |
20140293676 | PROGRAMMABLE IMPEDANCE MEMORY ELEMENTS AND CORRESPONDING METHODS - A memory element programmable between different impedance states can include a first electrode; a switching layer formed in contact with the first electrode and including at least one metal oxide; and a buffer layer in contact with the switching layer. A buffer layer can include a first metal, tellurium, a third element, and a second metal distributed within the buffer layer. A second electrode can be in contact with the buffer layer. | 10-02-2014 |
Jefry E. Shields, San Marcos, CA US
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20090023902 | Method for the extraction of intracellular proteins from a fermentation broth - A method for extracting an intracellular peptide, protein or other polypeptide from a whole fermentation broth using a water miscible alcohol, or a water miscible or partially water miscible glycol ether. | 01-22-2009 |
Jerome Shields, San Francisco, CA US
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20100321583 | Temporally Smoothing a Motion Estimate - For a frame set of a moving image sequence, a motion estimate is accessed. The motion estimate describes a change to a region of a reference frame with respect to at least one other frame. The reference frame and the other frames are displaced from each other within the frame set from over a temporal window. The regions of the two frames contain at least a portion of an image feature. The motion estimate is smoothed over the temporal window. The smoothing may facilitate aligning, at least in part, the image feature within the set of frames. | 12-23-2010 |
Jon Barton Shields, Escondido, CA US
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20140148197 | EMERGENCY, SECURITY, AND ACCESSIBILITY APPARATUS AND METHODS - Systems, methods, means and computer program products for determining a position of an object in an environment are disclosed. Certain systems, methods, means and computer program products carry out position determination for asset tracking, emergency evacuations, navigation and other uses. | 05-29-2014 |
Karl Richard Shields, North Hills, CA US
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20100113111 | Radiation Redirecting External Case For Portable Communication Device and Antenna Embedded In Battery of Portable Communication Device - An advanced antenna or set of antennae for a wireless device is provided by embedding the antennae into the battery case or generally the largest surface area of a wireless phone. The antenna connections are made through the battery's connections to the wireless device. The antenna design can be compact and located in any area of the battery. The antenna design can be thin and flat, located at the back surface of the battery or the large rear surface of a wireless phone, facing away from the user. An RF shielding device can be embedded into the battery and configured in relation to the antenna such that the RF field intensity and the consequent specific absorption rate for the user is lowered while the outgoing signals of the wireless device remain fully adequate for the function of the wireless device. This feature is preserved for a multi-band operation because a digital phase shifter is used between two radiating antennae. An external case is used as a complement to the wireless phone to provide additional antennae, power and capability. | 05-06-2010 |
20100234081 | RF RADIATION REDIRECTION AWAY FROM PORTABLE COMMUNICATION DEVICE USER - A case for a wireless device includes a number of RF coupling elements mounted in the case and configured such that RF radiation is coupled from an internal antenna of the wireless device out of the device to a first RF coupling element, and from the first RF coupling element to a RF redirector coupling element that redirects the RF radiation in a direction outward from said wireless device that is opposite to a user side of the wireless device. A corrugated metallic shield is optionally provided on an opposite side of the case, facing a user of the device. | 09-16-2010 |
20120044115 | External Case for Redistribution of RF Radiation Away From Wireless Communication Device User and Wireless Communication Device Incorporating RF Radiation Redistribution Elements - A case for a wireless tablet computer device includes a number of RF resonant loop elements and elongated RF director coupling strip elements mounted in the case and configured such that RF radiation is coupled from an internal antenna of the wireless device out of the device to the RF resonant and coupling elements. The case incorporates a cut-out section in a location leaving exposed a strip that covers an area proximate the internal antenna. The RF resonant loops and director coupling strip elements alternatively may be incorporated with the wireless tablet computer device itself. | 02-23-2012 |
20120309472 | RADIATION REDIRECTING EXTERNAL CASE FOR PORTABLE COMMUNICATION DEVICE AND ANTENNA EMBEDDED IN BATTERY OF PORTABLE COMMUNICATION DEVICE - An antenna or set of antennae for a wireless device is provided by embedding the antennae into the battery case or generally the surface area of a wireless phone. The antenna connections are through the battery's connections to the wireless device. The antenna can be located at the back surface of the battery or the rear surface of a wireless phone, facing away from the user. An RF shielding device can be embedded into the battery and configured in relation to the antenna such that the RF field intensity and the consequent specific absorption rate for the user is lowered while the outgoing signals of the wireless device remain fully adequate for the function of the wireless device. This feature is preserved for a multi-band operation because a digital phase shifter is used between two radiating antennae. An external case is used as a complement to the wireless phone. | 12-06-2012 |
20130252677 | RADIATION REDIRECTING ELEMENTS FOR PORTABLE COMMUNICATION DEVICE - An antenna or set of antennae for a wireless device is provided by embedding the antennae into the battery case or generally the surface area of a wireless phone. The antenna connections are through the battery's connections to the wireless device. The antenna can be located at the back surface of the battery or the rear surface of a wireless phone, facing away from the user. An RF shielding device can be embedded into the battery and configured in relation to the antenna such that the RF field intensity and the consequent specific absorption rate for the user is lowered while the outgoing signals of the wireless device remain fully adequate for the function of the wireless device. This feature is preserved for a multi-band operation because a digital phase shifter is used between two radiating antennae. An external case is used as a complement to the wireless phone. | 09-26-2013 |
20140287697 | RADIATION REDIRECTING ELEMENTS FOR PORTABLE COMMUNICATION DEVICE - An antenna or set of antennae for a wireless device is provided by embedding the antennae into the battery case or generally the surface area of a wireless phone. The antenna connections are through the battery's connections to the wireless device. The antenna can be located at the back surface of the battery or the rear surface of a wireless phone, facing away from the user. An RF shielding device can be embedded into the battery and configured in relation to the antenna such that the RF field intensity and the consequent specific absorption rate for the user is lowered while the outgoing signals of the wireless device remain fully adequate for the function of the wireless device. This feature is preserved for a multi-band operation because a digital phase shifter is used between two radiating antennae. An external case is used as a complement to the wireless phone. | 09-25-2014 |
20150077295 | RF RADIATION REDIRECTION AWAY FROM PORTABLE COMMUNICATION DEVICE USER - A case for a wireless device includes a number of RF coupling elements mounted in the case and configured such that RF radiation is coupled from an internal antenna of the wireless device out of the device to a first RF coupling element, and from the first RF coupling element to a RF redirector coupling element that redirects the RF radiation in a direction outward from said wireless device that is opposite to a user side of the wireless device. A corrugated metallic shield is optionally provided on an opposite side of the case, facing a user of the device. | 03-19-2015 |
Karl Richard Shields, Oceanside, CA US
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20150141089 | EXTERNAL CASE FOR REDISTRIBUTION OF RF RADIATION AWAY FROM WIRELESS COMMUNICATION DEVICE USER AND WIRELESS COMMUNICATION DEVICE INCORPORATING RF RADIATION REDISTRIBUTION ELEMENTS - A case for a wireless tablet computer device includes a number of RF resonant loop elements and elongated RF director coupling strip elements mounted in the case and configured such that RF radiation is coupled from an internal antenna of the wireless device out of the device to the RF resonant and coupling elements. The case incorporates a cut-out section in a location leaving exposed a strip that covers an area proximate the internal antenna. The RF resonant loops and director coupling strip elements alternatively may be incorporated with the wireless tablet computer device itself. | 05-21-2015 |
Kevin E. Shields, Santa Barbara, CA US
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20140097129 | PARTICLE MANIPULATION SYSTEM WITH CYTOMETRIC CONFIRMATION - A MEMS-based particle manipulation system which uses a particle manipulation stage and a plurality of laser interrogation regions. The laser interrogation regions may be used to assess the effectiveness or accuracy of the particle manipulation stage. In one exemplary embodiment, the particle manipulation stage is a microfabricated valve, which sorts a target particle from non-target particles in a fluid stream. The laser interrogation stages are disposed in the microfabricated fluid channels at the input and output of the valve. By reversing the flow from output to input, the same laser interrogation region may be used to perform the cytometry. The cytometry may be performed throughout the sorting process to optimize or control the sorting, or may be performed afterward to allow a multi-pass, sequential sort to be performed on the same sample. | 04-10-2014 |
20150093810 | Particle manipulation system with out-of-plane channel and focusing element - A particle manipulation system uses a MEMS-based, microfabricated particle manipulation device, which has an inlet channel, output channels, and a movable member formed on a substrate. The movable member moves parallel to the fabrication plane, as does fluid flowing in the inlet channel. The movable member separates a target particle from the rest of the particles, diverting it into an output channel. However, at least one output channel is not parallel to the fabrication plane. The device may be used to separate a target particle from non-target material in a sample stream. The target particle may be, for example, a stern cell, zygote, a cancer cell, a component of blood, bacteria or DNA sample, for example. The particle manipulation system may also include a microfluidic structure which focuses the target particles in a particular portion of the inlet channel. | 04-02-2015 |
20150093817 | Particle manipulation system with out-of plane channel - A particle manipulation system uses a MEMS-based, microfabricated particle manipulation device which has an inlet channel, output channels, and a movable member formed on a substrate. The movable member moves parallel to the fabrication plane, as does fluid flowing in the inlet channel. The movable member separates a target particle from the rest of the particles, diverting it into an output channel. However, at least one output channel is not parallel to the fabrication plane. The device may be used to separate a target particle from non-target material in a sample stream. The target particle may be, for example, a stem cell, zygote, a cancer cell, a T-cell, a component of blood, bacteria or DNA sample, for example. The particle manipulation system may also include a microfluidic structure which focuses the target particles in a particular portion of the inlet channel. | 04-02-2015 |
20150211685 | PARTICLE MANIPULATION SYSTEM WITH STAY-WET ALGORITHM - A MEMS-based particle manipulation system which uses a particle manipulation stage and a sensor to detect when the sample volume is exhausted or nearly exhausted. The sensor sends a signal to a fluid control means that reverses the pressure between one of the output channels and the input channels, to keep the surfaces wet with a volume of the sample fluid. This volume can be maintained in the channel until an operator intervenes, or it can be repeatedly shuttled back and forth between the input channel and an output channel. By keeping the channels wet, material from the sample stream does not become adhered to the channel walls, which might otherwise irreversibly change or damage the device. | 07-30-2015 |
Michael Shields, San Francisco, CA US
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20140104993 | SYSTEMS AND METHODS FOR PROVIDING WARNING OF ANOMALOUS ALARM CLOCK SETTINGS - Systems and methods relate to managing an alarm clock function of a device. The systems and methods for compare a time setting of a new alarm by a user to one or more previous times settings that the alarm has been set to determine whether to warn the user about and/or require the user to confirm the time setting of the new alarm. The systems and methods can detect a user input indicating a first time setting for the alarm clock function. Further, the systems and methods can examine the one or more previous time settings associated with the alarm clock function determine, based on the one or more previous time settings, whether to query the user to confirm an activation of the alarm clock function at the first time setting. | 04-17-2014 |
Robert L. Shields, San Mateo, CA US
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20090087428 | ANTI-FC-GAMMA RIIB RECEPTOR ANTIBODY AND USES THEREFOR - The present application describes antibodies that selectively bind human FcγRIIB, with little or no binding to other human FcγRs, e.g., human FcγRIIA. The invention also provides isolated bispecific antibodies comprising an antibody that selectively binds FcγRIIB, and a second antibody that specifically binds an activating receptor. Various uses, including therapeutic uses, for those antibodies are also described, including administration with anti-tumor antibodies and methods of inhibiting immune responses and suppressing histamine release. | 04-02-2009 |
Rodney M. Shields, Ukiah, CA US
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20130330486 | One-Way Graphics Materials and Methods - Included herein are base materials and methods for use in creation of one-way graphics, including a dye-receptive substrate with a pattern of ink-repellent material over the dye-receptive substrate. An image may be printed selectively onto the base material to leave a visual perforation pattern that allows vision through the printed image under appropriate illumination. Also disclosed are printing methods involving the application of variously ordered layers of light-absorbing, light-reflective, and image mediums to printing substrates with physically raised and lowered areas to create one-way graphics. The invention also includes new forms of one-way graphics, including lenticular and holographic one-way displays, and one-way displays having internal lighting sources. | 12-12-2013 |
20130335716 | Projection Graphics Using One-Way Vision Screens - A method and apparatus for one-way graphics using a projector that projects an image onto a screen, wherein the screen is comprised of a non-transparent material, and the screen contains voids sufficient in size and distribution to allow clarity of vision when viewed through from the side opposite the projection, and wherein the area of the screen substantially reflects the projected image so that on observer viewing the screen from the projection side of the screen sees the image that is projected onto the screen. The apparatus and method may further comprise a light-absorbing layer on the back of the screen, wherein the voids in the screen extend through the light-absorbing layer. The one-way screen may include additional transparent layers for mounting and adhesion. | 12-19-2013 |
20130335809 | Dynamically Variable Graphic Material Using Electrostatically Attracted Particles - Dynamically-variable graphic displays, including a panel comprised of colored microspheres, each a single pixel with an embedded electrical charge; one or more electrodes capable of receiving an electrical charge, each electrode situated so that it can interact with at least one of said microspheres; an energy source connected to the electrodes via conductive elements capable of changing the polarity of said electrodes, such change in polarity causing the microspheres to move to change the color displayed to a viewer; and a substrate. Also included within the invention are dynamically-variable graphic display panels that enable one-way graphics through distribution of pixels to create image and silhouette patterns, wherein the image pattern is visible from the front of the panel under conditions of illumination, and wherein the silhouette pattern creates a substantially transparent area of clear vision from the back of the display panel through the panel. | 12-19-2013 |
20140259534 | MODULAR TELESCOPING POWER POLE AND BAR CLAMP/SPREADER TOOL - The invention is a set of modular telescoping tools. A first preferred embodiment is a power-transmitting telescoping extension pole, to which various specialized tools, including power tools, may be attached. The apparatus comprises an inner tube and outer tube, wherein the outer tube receives said inner tube, a coupling at the tool-end of the pole, a power transmission, capable of transmitting power from the user-end of the pole to the tool-end of the pole, and a control mechanism attached to the telescopic tube at the user-end of the telescopic tube. A second preferred embodiment is a set of telescoping bar clamps and spreader tools. In the simplest embodiment, the invention comprises a telescoping tube and a set of jaws, wherein the telescoping tube includes a first shaft having a first diameter, a second shaft having a second diameter that is less than the first diameter, and a locking mechanism. | 09-18-2014 |
20140261382 | Self-Warming Container - An apparatus for warming substances comprising a container, said container including a first compartment containing a substance that reacts exothermically with water, a second compartment containing water, wherein said second compartment is attached to said first compartment by a valve, and a third compartment, wherein at least 50% of the third compartment's volume is surrounded by said first compartment, and wherein said first and third compartments are separated by a thermally conductive wall. In a preferred embodiment, the substance that reacts exothermically with water is an anhydrous zeolite. | 09-18-2014 |
20140262737 | WAVE PISTON DESALINATOR - An apparatus and method for desalination use kinetic energy in ocean waves as a power source. The apparatus comprises a wave tank and a condensation tank, the wave tank and condensation tank being connected by two pipes, each with a one-way valve, that produced a cycle of water saturated air from the wave tank to the condensation tank with a return of relatively desaturated air back to the wave tank following condensation of water. The wave tank captures the up and down motion of the waves and converts it to a pumping action. Air inside the wave tank is compressed when a wave comes in and has a negative pressure when the wave recedes. A saline water spray is introduced during wave troughs. Water evaporates into the negative pressure air hydrating the air. When the next wave comes in the water level rises inside the wave tank pressurizing the air. | 09-18-2014 |
20140263733 | Self-Regulating Irrigation Controller - A self-regulating irrigation system utilizing a hydro-expansive material to regulate fluid flow. an irrigation control valve that includes (i) a sprinkler with a control valve, wherein said control valve comprises a control spring and a diaphragm located within the sprinkler head, (ii) a base extending down from said sprinkler head, and (iii) a hydro-expansive control membrane attached to the diaphragm and the base. The hydro-expansive control membrane is a length of hydro-expansive material that is short enough and strong enough to overcome the force of the control spring when the control membrane is dry, yet long enough that it will extend when wet so that the force of the control spring overcomes the force of the control membrane to close the diaphragm. | 09-18-2014 |
20140270901 | Zip Fasteners and Binders - An apparatus and method for binding sheets of material, comprising two mating binding strips are placed on opposite sides of a stack of sheets of perforated material, such that retaining surfaces can hold the sheets of material together in a bound volume. The binding strips mate via retaining straps that lock using a zip or ratcheting mechanism in the fastening head. At least one retaining tooth on the fastening head catches with a ratchet tooth on the retaining strip. In one preferred embodiment, one binding strip has at least two flexible retaining strips of notched material having at least one surface covered with detents, ridges, or retaining teeth. The female binding strip (or “locking strip”) has a plurality of fastening heads with locking mechanisms such as pawls. Each fastening head receives a retaining strip through a receiving passageway oriented in the same plane as the sheets of bound material. | 09-18-2014 |
20140298627 | Hook-and-Loop Fastener - A fastening system comprising a sheet of filaments that form a plurality of loops that are bent to form hooks, attached to a support matrix, such that when a first sheet and second sheet of filaments are brought into contact, the hooks can mate with the loops of the opposing sheet in a reversible locking position. In a second embodiment, the fastening system comprises a first base material having a multiplicity of filament loops and a second base material having a carpet of straight filaments, each filament having at least one notch sized to lock onto the filament loops of the first base material. Methods for manufacturing said materials are also described. | 10-09-2014 |
Rodney M. Shields, Potter Valley, CA US
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20150286046 | Dynamically Variable Graphic Material Using Electrostatically Attracted Particles - Dynamically-variable graphic displays, including a panel comprised of a plurality of electrostatic particles and a plurality of electrodynamic contacts supported within a nonconductive substrate, wherein each electrostatic particle is situated within a channel in the nonconductive substrate such that the nonconductive substrate comprises a plurality of channels oriented in one direction. Also included within the invention are dynamically-variable graphic display panels comprising electrostatic particles that each comprise a plurality of sectors, each having a different color and a fixed magnetic polarity relative to said sectors, and a plurality of electrodynamic contacts, each contact located adjacent to an electrostatic particle and positioned for interaction with one of the electrostatic particles. | 10-08-2015 |
Sharon J. Shields, San Ramon, CA US
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20090068065 | Simple, Field Portable Colorimetric Detection Device For Organic Peroxides and Hydrogen Peroxide - A simple and effective system for the calorimetric determination of organic peroxides and hydrogen peroxide. A peroxide pen utilizing a swipe material attached to a polyethylene tube contains two crushable vials. The two crushable vials contain a calorimetric reagent separated into dry ingredients and liquid ingredients. After swiping a suspected substance or surface the vials are broken, the reagent is mixed thoroughly and the reagent is allowed to wick into the swipe material. The presence of organic peroxides or hydrogen peroxide is confirmed by a deep blue color. | 03-12-2009 |
Steven C. Shields, Newport Beach, CA US
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20090094653 | METHOD AND SYSTEM FOR SIMULTANEOUS CONFERENCING AND INTERACTIVE DISPLAY AND CONTROL OF VIDEO OVER A DISTRIBUTED NETWORK - A video is played simultaneously at different nodes of a distributed network. The simultaneous playing is controlled through an intermediary server, which receives playback instructions from one or more of the different nodes and then sends simultaneous playback commands each of the different nodes in response to the playback instructions. The different nodes then play the video in accordance with the playback commands. | 04-09-2009 |
Steven E. Shields, San Diego, CA US
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20120170633 | Method and System for Communication Channel Characterization - In accordance with the present invention, a method of processing a signal is described that includes receiving a signal having an encoded digital packet, wherein the digital packet includes packet data and a packet frame, wherein the packet frame includes a common digital signal that is common to each one of a plurality of digital packets. The method further includes sampling a signal associated with the received signal to provide a sampled signal. The method further includes performing a channel characterization by contrasting a signal representative of the sampled signal with a signal representative of the common digital signal. A corresponding system is also described. | 07-05-2012 |
Tom Shields, San Mateo, CA US
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20110131099 | Method and Apparatus for Maximizing Publisher Revenue - A computer implemented method for maximizing publisher revenue for online advertising is provided. The computer implemented method includes determining a ratio of guaranteed ad impressions to expected remaining ad impressions. If the ratio is less than a threshold, the method includes, identifying a minimum bid value, the minimum bid value based on the ratio; comparing the minimum bid value to a received bid value for an ad impression; allocating the ad impression to an owner of the received bid when the received bid value is greater than or equal to the minimum bid value; and displaying an ad of the owner of the received bid. If the ratio is greater than the threshold, the method includes, allocating the ad impression to an owner of the guaranteed ad impressions. In one embodiment, the method operations are stored on a computer readable storage medium. | 06-02-2011 |