Murthy, US
Akshay Locharia Murthy, New York, NY US
Patent application number | Description | Published |
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20130041849 | Methods and Systems for Providing a Municipal Index Swap - In at least one aspect the invention comprises a computer-implemented method comprising: (a) electronically receiving data regarding characteristics of a plurality of tax exempt municipal bonds; (b) electronically receiving data describing a plurality of rules for inclusion of the tax exempt municipal bonds in a municipal bond index; (c) constructing a municipal bond index by applying the rules to characteristics of the plurality of tax exempt municipal bonds; and (d) quoting a municipal swap having a reference index, wherein the reference index is the municipal bond index. Other aspects comprise related computer systems and apparatuses, as well as various embodiments. | 02-14-2013 |
Akshay Locharla Murthy, New York, NY US
Patent application number | Description | Published |
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20100191671 | METHODS AND SYSTEMS FOR PROVIDING A MUNICIPAL INDEX SWAP - In at least one aspect the invention comprises a computer-implemented method comprising: (a) electronically receiving data regarding characteristics of a plurality of tax exempt municipal bonds; (b) electronically receiving data describing a plurality of rules for inclusion of the tax exempt municipal bonds in a municipal bond index; (c) constructing a municipal bond index by applying the rules to characteristics of the plurality of tax exempt municipal bonds; and (d) quoting a municipal swap having a reference index, wherein the reference index is the municipal bond index. Other aspects comprise related computer systems and apparatuses, as well as various embodiments. | 07-29-2010 |
Anand S. Murthy, Portland, OR US
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20080242061 | PRECURSOR GAS MIXTURE FOR DEPOSITING AN EPITAXIAL CARBON-DOPED SILICON FILM - A precursor gas mixture for depositing an epitaxial carbon-doped silicon film is described. The precursor gas mixture is comprised of a volume of a silicon precursor gas, a volume of acetylene gas and a volume of a carrier gas. A method of forming a semiconductor structure having an epitaxial carbon-doped silicon film is also described. In the method, a substrate having a high polarity dielectric region and a low polarity crystalline region is provided. A precursor gas is flowed to provide a silyl surface above the high polarity dielectric region and a carbon-doped silicon layer above the low polarity crystalline region. The silyl surface is then removed from above the high polarity dielectric region. The flowing and removing steps are repeated to provide a carbon-doped silicon film of a desired thickness above the low polarity crystalline region. | 10-02-2008 |
20090011565 | Field effect transistor structure with abrupt source/drain junctions - Microelectronic structures embodying the present invention include a field effect transistor (FET) having highly conductive source/drain extensions. Formation of such highly conductive source/drain extensions includes forming a passivated recess which is back filled by epitaxial deposition of doped material to form the source/drain junctions. The recesses include a laterally extending region that underlies a portion of the gate structure. Such a lateral extension may underlie a sidewall spacer adjacent to the vertical sidewalls of the gate electrode, or may extend further into the channel portion of a FET such that the lateral recess underlies the gate electrode portion of the gate structure. In one embodiment the recess is back filled by an in-situ epitaxial deposition of a bilayer of oppositely doped material. In this way, a very abrupt junction is achieved that provides a relatively low resistance source/drain extension and further provides good off-state subthreshold leakage characteristics. Alternative embodiments can be implemented with a back filled recess of a single conductivity type. | 01-08-2009 |
20100133595 | FIELD EFFECT TRANSISTOR STRUCTURE WITH ABRUPT SOURCE/DRAIN JUNCTIONS - Microelectronic structures embodying the present invention include a field effect transistor (FET) having highly conductive source/drain extensions. Formation of such highly conductive source/drain extensions includes forming a passivated recess which is back filled by epitaxial deposition of doped material to form the source/drain junctions. The recesses include a laterally extending region that underlies a portion of the gate structure. Such a lateral extension may underlie a sidewall spacer adjacent to the vertical sidewalls of the gate electrode, or may extend further into the channel portion of a FET such that the lateral recess underlies the gate electrode portion of the gate structure. In one embodiment the recess is back filled by an in-situ epitaxial deposition of a bilayer of oppositely doped material. In this way, a very abrupt junction is achieved that provides a relatively low resistance source/drain extension and further provides good off-state subthreshold leakage characteristics. Alternative embodiments can be implemented with a back filled recess of a single conductivity type. | 06-03-2010 |
20100151669 | FORMING ABRUPT SOURCE DRAIN METAL GATE TRANSISTORS - A gate structure may be utilized as a mask to form source and drain regions. Then the gate structure may be removed to form a gap and spacers may be formed in the gap to define a trench. In the process of forming a trench into the substrate, a portion of the source drain region is removed. Then the substrate is filled back up with an epitaxial material and a new gate structure is formed thereover. As a result, more abrupt source drain junctions may be achieved. | 06-17-2010 |
20110147828 | SEMICONDUCTOR DEVICE HAVING DOPED EPITAXIAL REGION AND ITS METHODS OF FABRICATION - Embodiments of the present invention describe a epitaxial region on a semiconductor device. In one embodiment, the epitaxial region is deposited onto a substrate via cyclical deposition-etch process. Cavities created underneath the spacer during the cyclical deposition-etch process are backfilled by an epitaxial cap layer. The epitaxial region and epitaxial cap layer improves electron mobility at the channel region, reduces short channel effects and decreases parasitic resistance. | 06-23-2011 |
20110147842 | MULTI-GATE SEMICONDUCTOR DEVICE WITH SELF-ALIGNED EPITAXIAL SOURCE AND DRAIN - A channel strained multi-gate transistor with low parasitic resistance and method of manufacturing the same. A gate stack may be formed over a semiconductor fin having a gate-coupled sidewall height (H | 06-23-2011 |
20120153387 | TRANSISTORS WITH HIGH CONCENTRATION OF BORON DOPED GERMANIUM - Techniques are disclosed for forming transistor devices having source and drain regions with high concentrations of boron doped germanium. In some embodiments, an in situ boron doped germanium, or alternatively, boron doped silicon germanium capped with a heavily boron doped germanium layer, are provided using selective epitaxial deposition in the source and drain regions and their corresponding tip regions. In some such cases, germanium concentration can be, for example, in excess of 50 atomic % and up to 100 atomic %, and the boron concentration can be, for instance, in excess of 1E20 cm | 06-21-2012 |
20130154016 | TIN DOPED III-V MATERIAL CONTACTS - Techniques are disclosed for forming transistor devices having reduced parasitic contact resistance relative to conventional devices. The techniques can be implemented, for example, using a metal contact such as one or more metals/alloys on silicon or silicon germanium (SiGe) source/drain regions. In accordance with one example embodiment, an intermediate tin doped III-V material layer is provided between the source/drain and contact metal to significantly reduce contact resistance. Partial or complete oxidation of the tin doped layer can be used to further improve contact resistance. In some example cases, the tin doped III-V material layer has a semiconducting phase near the substrate and an oxide phase near the metal contact. Numerous transistor configurations and suitable fabrication processes will be apparent in light of this disclosure, including both planar and non-planar transistor structures (e.g., FinFETs, nanowire transistors, etc), as well as strained and unstained channel structures. | 06-20-2013 |
20130161756 | NANOWIRE TRANSISTOR DEVICES AND FORMING TECHNIQUES - Techniques are disclosed for customization of nanowire transistor devices to provide a diverse range of channel configurations and/or material systems within the same integrated circuit die. In accordance with one example embodiment, sacrificial fins are removed and replaced with custom material stacks of arbitrary composition and strain suitable for a given application. In one such case, each of a first set of the sacrificial fins is recessed or otherwise removed and replaced with a p-type layer stack, and each of a second set of the sacrificial fins is recessed or otherwise removed and replaced with an n-type layer stack. The p-type layer stack can be completely independent of the process for the n-type layer stack, and vice-versa. Numerous other circuit configurations and device variations are enabled using the techniques provided herein. | 06-27-2013 |
20130240989 | SELECTIVE GERMANIUM P-CONTACT METALIZATION THROUGH TRENCH - Techniques are disclosed for forming transistor devices having reduced parasitic contact resistance relative to conventional devices. The techniques can be implemented, for example, using a standard contact stack such as a series of metals on, for example, silicon or silicon germanium (SiGe) source/drain regions. In accordance with one example such embodiment, an intermediate boron doped germanium layer is provided between the source/drain and contact metals to significantly reduce contact resistance. Numerous transistor configurations and suitable fabrication processes will be apparent in light of this disclosure, including both planar and non-planar transistor structures (e.g., FinFETs), as well as strained and unstrained channel structures. Graded buffering can be used to reduce misfit dislocation. The techniques are particularly well-suited for implementing p-type devices, but can be used for n-type devices if so desired. | 09-19-2013 |
20130248999 | CONTACT RESISTANCE REDUCTION EMPLOYING GERMANIUM OVERLAYER PRE-CONTACT METALIZATION - Techniques are disclosed for forming transistor devices having reduced parasitic contact resistance relative to conventional devices. The techniques can be implemented, for example, using a standard contact stack such as a series of metals on, for example, silicon or silicon germanium (SiGe) source/drain regions. In accordance with one example such embodiment, an intermediate boron doped germanium layer is provided between the source/drain and contact metals to significantly reduce contact resistance. Numerous transistor configurations and suitable fabrication processes will be apparent in light of this disclosure, including both planar and non-planar transistor structures (e.g., FinFETs), as well as strained and unstrained channel structures. Graded buffering can be used to reduce misfit dislocation. The techniques are particularly well-suited for implementing p-type devices, but can be used for n-type devices if so desired. | 09-26-2013 |
20130264639 | COLUMN IV TRANSISTORS FOR PMOS INTEGRATION - Techniques are disclosed for forming column IV transistor devices having source/drain regions with high concentrations of germanium, and exhibit reduced parasitic resistance relative to conventional devices. In some example embodiments, the source/drain regions each includes a thin p-type silicon or germanium or SiGe deposition with the remainder of the source/drain material deposition being p-type germanium or a germanium alloy (e.g., germanium:tin or other suitable strain inducer, and having a germanium content of at least 80 atomic % and 20 atomic % or less other components). In some cases, evidence of strain relaxation may be observed in the germanium rich cap layer, including misfit dislocations and/or threading dislocations and/or twins. Numerous transistor configurations can be used, including both planar and non-planar transistor structures (e.g., FinFETs and nanowire transistors), as well as strained and unstrained channel structures. | 10-10-2013 |
20130277752 | SELF-ALIGNED CONTACT METALLIZATION FOR REDUCED CONTACT RESISTANCE - Techniques are disclosed for forming low contact resistance transistor devices. A p-type germanium layer is provided between p-type source/drain regions and their respective contact metals, and an n-type III-V semiconductor material layer is provided between n-type source/drain regions and their respective contact metals. The n-type III-V semiconductor material layer may have a small bandgap (e.g., <0.5 eV) and/or otherwise be doped to provide desired conductivity, and the p-type germanium layer can be doped, for example, with boron. After deposition of the III-V material over both the n-type source/drain regions and the germanium covered p-type source/drain regions, an etch-back process can be performed to take advantage of the height differential between n and p type regions to self-align contact types and expose the p-type germanium over p-type regions and thin the n-type III-V material over the n-type regions. The techniques can be used on planar and non-planar transistor architectures. | 10-24-2013 |
20130285155 | III-V LAYERS FOR N-TYPE AND P-TYPE MOS SOURCE-DRAIN CONTACTS - Techniques are disclosed for forming transistor devices having reduced parasitic contact resistance relative to conventional devices. In some example embodiments, the techniques can be used to implement the contacts of MOS transistors of a CMOS device, where an intermediate III-V semiconductor material layer is provided between the p-type and n-type source/drain regions and their respective contact metals to significantly reduce contact resistance. The intermediate III-V semiconductor material layer may have a small bandgap (e.g., lower than 0.5 eV) and/or otherwise be doped to provide the desired conductivity. The techniques can be used on numerous transistor architectures (e.g., planar, finned, and nanowire transistors), including strained and unstrained channel structures. | 10-31-2013 |
20140001441 | INTEGRATION METHODS TO FABRICATE INTERNAL SPACERS FOR NANOWIRE DEVICES | 01-02-2014 |
20140001520 | CONTACT RESISTANCE REDUCED P-MOS TRANSISTORS EMPLOYING GE-RICH CONTACT LAYER | 01-02-2014 |
20140027816 | HIGH MOBILITY STRAINED CHANNELS FOR FIN-BASED TRANSISTORS - Techniques are disclosed for incorporating high mobility strained channels into fin-based transistors (e.g., FinFETs such as double-gate, trigate, etc), wherein a stress material is cladded onto the channel area of the fin. In one example embodiment, silicon germanium (SiGe) is cladded onto silicon fins to provide a desired stress, although other fin and cladding materials can be used. The techniques are compatible with typical process flows, and the cladding deposition can occur at a plurality of locations within the process flow. In some cases, the built-in stress from the cladding layer may be enhanced with a source/drain stressor that compresses both the fin and cladding layers in the channel. In some cases, an optional capping layer can be provided to improve the gate dielectric/semiconductor interface. In one such embodiment, silicon is provided over a SiGe cladding layer to improve the gate dielectric/semiconductor interface. | 01-30-2014 |
20140027860 | SELF-ALIGNED 3-D EPITAXIAL STRUCTURES FOR MOS DEVICE FABRICATION - Techniques are disclosed for customization of fin-based transistor devices to provide a diverse range of channel configurations and/or material systems within the same integrated circuit die. In accordance with one example embodiment, sacrificial fins are removed and replaced with custom semiconductor material of arbitrary composition and strain suitable for a given application. In one such case, each of a first set of the sacrificial fins is recessed or otherwise removed and replaced with a p-type material, and each of a second set of the sacrificial fins is recessed or otherwise removed and replaced with an n-type material. The p-type material can be completely independent of the process for the n-type material, and vice-versa. Numerous other circuit configurations and device variations are enabled using the techniques provided herein. | 01-30-2014 |
20140084369 | SEMICONDUCTOR DEVICE HAVING DOPED EPITAXIAL REGION AND ITS METHODS OF FABRICATION - Embodiments of the present invention describe a epitaxial region on a semiconductor device. In one embodiment, the epitaxial region is deposited onto a substrate via cyclical deposition-etch process. Cavities created underneath the spacer during the cyclical deposition-etch process are backfilled by an epitaxial cap layer. The epitaxial region and epitaxial cap layer improves electron mobility at the channel region, reduces short channel effects and decreases parasitic resistance. | 03-27-2014 |
20140175543 | CONVERSION OF THIN TRANSISTOR ELEMENTS FROM SILICON TO SILICON GERMANIUM - Embodiments of the present disclosure provide techniques and configurations associated with conversion of thin transistor elements from silicon (Si) to silicon germanium (SiGe). In one embodiment, a method includes providing a semiconductor substrate having a channel body of a transistor device disposed on the semiconductor substrate, the channel body comprising silicon, forming a cladding layer comprising germanium on the channel body, and annealing the channel body to cause the germanium to diffuse into the channel body. Other embodiments may be described and/or claimed. | 06-26-2014 |
20140197377 | CMOS NANOWIRE STRUCTURE - Complimentary metal-oxide-semiconductor nanowire structures are described. For example, a semiconductor structure includes a first semiconductor device. The first semiconductor device includes a first nanowire disposed above a substrate. The first nanowire has a mid-point a first distance above the substrate and includes a discrete channel region and source and drain regions on either side of the discrete channel region. A first gate electrode stack completely surrounds the discrete channel region of the first nanowire. The semiconductor structure also includes a second semiconductor device. The second semiconductor device includes a second nanowire disposed above the substrate. The second nanowire has a mid-point a second distance above the substrate and includes a discrete channel region and source and drain regions on either side of the discrete channel region. The first distance is different from the second distance. A second gate electrode stack completely surrounds the discrete channel region of the second nanowire. | 07-17-2014 |
20140239345 | STRAINED TRANSISTOR INTEGRATION FOR CMOS - Various embodiments of the invention relate to a CMOS device having (1) an NMOS channel of silicon material selectively deposited on a first area of a graded silicon germanium substrate such that the selectively deposited silicon material experiences a tensile strain caused by the lattice spacing of the silicon material being smaller than the lattice spacing of the graded silicon germanium substrate material at the first area, and (2) a PMOS channel of silicon germanium material selectively deposited on a second area of the substrate such that the selectively deposited silicon germanium material experiences a compressive strain caused by the lattice spacing of the selectively deposited silicon germanium material being larger than the lattice spacing of the graded silicon germanium substrate material at the second area. | 08-28-2014 |
20150054031 | TIN DOPED III-V MATERIAL CONTACTS - Techniques are disclosed for forming transistor devices having reduced parasitic contact resistance relative to conventional devices. The techniques can be implemented, for example, using a metal contact such as one or more metals/alloys on silicon or silicon germanium (SiGe) source/drain regions. In accordance with one example embodiment, an intermediate tin doped III-V material layer is provided between the source/drain and contact metal to significantly reduce contact resistance. Partial or complete oxidation of the tin doped layer can be used to further improve contact resistance. In some example cases, the tin doped III-V material layer has a semiconducting phase near the substrate and an oxide phase near the metal contact. Numerous transistor configurations and suitable fabrication processes will be apparent in light of this disclosure, including both planar and non-planar transistor structures (e.g., FinFETs, nanowire transistors, etc), as well as strained and unstrained channel structures. | 02-26-2015 |
20150060945 | TRANSISTORS WITH HIGH CONCENTRATION OF BORON DOPED GERMANIUM - Techniques are disclosed for forming transistor devices having source and drain regions with high concentrations of boron doped germanium. In some embodiments, an in situ boron doped germanium, or alternatively, boron doped silicon germanium capped with a heavily boron doped germanium layer, are provided using selective epitaxial deposition in the source and drain regions and their corresponding tip regions. In some such cases, germanium concentration can be, for example, in excess of 50 atomic % and up to 100 atomic %, and the boron concentration can be, for instance, in excess of 1E20 cm | 03-05-2015 |
20150069473 | TRANSISTOR FABRICATION TECHNIQUE INCLUDING SACRIFICIAL PROTECTIVE LAYER FOR SOURCE/DRAIN AT CONTACT LOCATION - Techniques are disclosed for transistor fabrication including a sacrificial protective layer for source/drain (S/D) regions to minimize contact resistance. The sacrificial protective layer may be selectively deposited on S/D regions after such regions have been formed, but prior to the deposition of an insulator layer on the S/D regions. Subsequently, after contact trench etch is performed, an additional etch process may be performed to remove the sacrificial protective layer and expose a clean S/D surface. Thus, the sacrificial protective layer can protect the contact locations of the S/D regions from contamination (e.g., oxidation or nitridation) caused by insulator layer deposition. The sacrificial protective layer can also protect the S/D regions from undesired insulator material remaining on the S/D contact surface, particularly for non-planar transistor structures (e.g., finned or nanowire/nanoribbon transistor structures). | 03-12-2015 |
Anupama V. Murthy, Omaha, NE US
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20090119133 | METHOD AND SYSTEM FOR POLICY UNDERWRITING AND RISK MANAGEMENT OVER A NETWORK - A system and method for collecting insurance information, providing premium quotations, and automating policy issuance and claim processing. An embodiment utilizes automated, task-based work flow process that enables all parties to work efficiently to issue policies and handle policies. | 05-07-2009 |
Ashlesh K. Murthy, San Antonio, TX US
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20090098165 | METHODS AND COMPOSITIONS FOR IMMUNIZATION AGAINST CHLAMYDIAL INFECTION AND DISEASE - The present invention provides | 04-16-2009 |
20110123491 | METHODS AND COMPOSITIONS FOR IMMUNIZATION AGAINST CHLAMYDIAL INFECTION AND DISEASE - The present invention provides | 05-26-2011 |
Ashok Murthy, Tualatin, OR US
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20100264214 | METHOD AND SYSTEM FOR PROVIDING CONTRACT-FREE "PAY-AS-YOU-GO" OPTIONS FOR UTILIZATION OF MULTI-FUNCTION DEVICES - A method and system including a plurality of multifunctional devices being operatively associated with at least one controller and each having a preset amount of preloaded consumables at a time of initial use; and a software application for enabling at least one user to access the plurality of multifunctional devices, the software application being configured to receive information from a prepaid card, the information including a financial value relating to usage of some of the preset amount of preloaded consumables in the plurality of multifunctional devices; wherein the financial value of the prepaid card is applied by the at least one user across the plurality of multifunctional devices in any desired uniform or non-uniform financial proportions in accordance with usage determinations; and wherein the at least one user is enabled to pay for access to the plurality of multifunctional devices in time staggered installments without pre-established contractual obligations. | 10-21-2010 |
20110188067 | PRE-PAID DOCUMENT PROCESSING DEVICES AND OPERATING METHODS - Document processing devices and methods are presented, in which the device stores a remaining print unit value in its memory that represents the amount of print units currently available to enable the device to perform the document processing operations, and a programmable computer of the device selectively performs document processing jobs for users and decrements the remaining print unit value until the value reaches zero and the device provides for expenditure of print units according to color content and/or coverage levels determined for a given job. | 08-04-2011 |
20110191148 | METHODS AND APPARATUS FOR MANAGING PRE-PAID PRINTING SYSTEM ACCOUNTS - Methods and systems are presented for managing document processing device usage in which a customer accesses a management system to buy and pay for account credits, and to apply print units to specific managed device by conversion of account credits based on current pricing information for the specified account and the particular device at the time of the request. | 08-04-2011 |
Ashwin Murthy, Bellevue, WA US
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20130185404 | EFFICIENT PORT MANAGEMENT FOR A DISTRIBUTED NETWORK ADDRESS TRANSLATION - A central NAT manager efficiently allocates ports to endpoints of a tenant application in a hosting environment for NAT purposes. In some instances, the central NAT manager may pre-allocate ports to endpoints as part of the initial configuration of the tenant application. The pre-allocation process may include persisting pre-allocated port state information in storage and configuring endpoints and a NAT device with the pre-allocated port state information. Additional ports may be dynamically allocated to endpoints during runtime using dynamically determined port allocation sizes. In other instances, the central NAT manager may reserve ports for endpoints during the initial configuration of the tenant application by assigning ports to endpoints and persisting port assignment information to storage. During runtime, endpoints may issue port allocation requests to the central NAT manager, which may allocate ports to the endpoints from the range of ports initially reserved for each endpoint. | 07-18-2013 |
20140019602 | LOAD BALANCING FOR SINGLE-ADDRESS TENANTS - Load balancing for single-address tenants. When a load balancer detects that a virtual address is associated with a single destination address, the load balancer sets a flag to distinguish the virtual address from virtual addresses that are associated with a plurality of destination addresses. The load balancer instructs the router to bypass the load balancer for network packets that are addressed to the virtual address, and refrains from storing subsequent flow state for the virtual address. When the virtual address is to be scaled up with an additional destination address, the load balancer sets a flag to distinguish the virtual address from virtual addresses that are associated with a single destination addresses. The load balancer instructs the router to route network packets that are addressed to the virtual address through the load balancer, instead of bypassing the load balancer, and starts storing flow state for the virtual address. | 01-16-2014 |
20140351395 | LOAD BALANCING FOR SINGLE-ADDRESS TENANTS - When a load balancer detects that a virtual address is associated with a single destination address, the load balancer sets a flag to distinguish the virtual address from virtual addresses that are associated with a plurality of destination addresses. The load balancer instructs the router to bypass the load balancer for network packets that are addressed to the virtual address, and refrains from storing subsequent flow state for the virtual address. When the virtual address is to be scaled up with an additional destination address, the load balancer sets a flag to distinguish the virtual address from virtual addresses that are associated with a single destination addresses. The load balancer instructs the router to route network packets that are addressed to the virtual address through the load balancer, instead of bypassing the load balancer, and starts storing flow state for the virtual address. | 11-27-2014 |
20140373146 | DOS DETECTION AND MITIGATION IN A LOAD BALANCER - A load balancer that is able to detect and mitigate a Denial of Service (DOS) attack. The load balancer is placed in the flow path of network data packets that are destined for one or more tenant addresses. The load balancer analyzes performance parameters regarding the network data packets that are destined for the one or more tenant addresses and are received at the load balancer. The performance parameters describe network data packet flow to the tenant addresses. The load balancer detects, based on the analysis of the performance parameters, that one or more of the tenant addresses are being subjected to a DOS attack. The load balancer performs a mitigation operation to isolate the one or more tenant addresses being subjected to the DOS attack. | 12-18-2014 |
Avinash K. Murthy, Austin, TX US
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20130023714 | Medical and Imaging Nanoclusters - In one embodiment the present invention discloses a nanocluster or a nanorose composition comprising two or more closely spaced nanoparticles each comprising one or more metals, metal oxides, inorganic substances, or a combination thereof and one or more stabilizers. The stabilizers are in contact with the two or more closely spaced nanoparticles to form a nanocluster composition in which the inorganic weight percentage is greater than 50% and the average size is below 300 nm, and the nanocluster composition has magnetic properties, optical properties or a combination of both. | 01-24-2013 |
Bala K. Murthy, Troy, MI US
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20090173311 | ENGINE CONTROL SYSTEM FOR INCREASED VEHICLE FUEL ECONOMY - An engine control system comprises a driver input module, a cylinder actuation module, and an active fuel management (AFM) module. The driver input module generates a fuel saver mode (FSM) signal having a first state based upon a driver input. The cylinder actuation module selectively disables at least one of a plurality of cylinders of an engine based upon a deactivation signal having a first state. The AFM module generates the deactivation signal based on at least one engine parameter and at least one threshold. The at least one threshold is modified when the FSM signal has the first state. | 07-09-2009 |
Chetan Murthy, Gainesville, FL US
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20100223237 | LOSSLESS DATA COMPRESSION AND REAL-TIME DECOMPRESSION - A method, information processing system, and computer program storage product store data in an information processing system. Uncompressed data is received and the uncompressed data is divided into a series of vectors. A sequence of profitable bitmask patterns is identified for the vectors that maximizes compression efficiency while minimizes decompression penalty. Matching patterns are created using multiple bit masks based on a set of maximum values of the frequency distribution of the vectors. A dictionary is built based upon the set of maximum values in the frequency distribution and a bit mask savings which is a number of bits reduced using each of the multiple bit masks. Each of the vectors is compressed using the dictionary and the matching patterns with having high bit mask savings. The compressed vectors are stored into memory. Also, an efficient placement is developed to enable parallel decompression of the compressed codes. | 09-02-2010 |
Kalpana C. Murthy, Plano, TX US
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20090129267 | SYSTEM AND METHOD FOR DISCOVERING SCTP ASSOCIATIONS IN A NETWORK - Systems and methods for discovering SCTP associations between devices communicating in a network are described. A method comprises monitoring packets communicated among a plurality of source and destination devices, determining a combination of source EP address, source port number, destination IP address, and destination port number that defines an association between a source device and a destination device, and resolving a combination of source and destination verification tags that further defines the association based upon the combination of EP addresses and port numbers. The method further comprises ascertaining whether a subsequently monitored packet belongs to the association based at least in part upon an element of the combination of verification tags after at least one element of the combination of EP addresses and port numbers has changed during the ongoing communication. | 05-21-2009 |
20120147776 | SYSTEMS AND METHODS FOR DISCOVERING SCTP ASSOCIATIONS IN A NETWORK - Systems and methods for discovering SCTP associations between devices communicating in a network are described. A method comprises monitoring packets communicated among a plurality of source and destination devices, determining a combination of source EP address, source port number, destination IP address, and destination port number that defines an association between a source device and a destination device, and resolving a combination of source and destination verification tags that further defines the association based upon the combination of EP addresses and port numbers. The method further comprises ascertaining whether a subsequently monitored packet belongs to the association based at least in part upon an element of the combination of verification tags after at least one element of the combination of EP addresses and port numbers has changed during the ongoing communication. | 06-14-2012 |
Kanneganti Murthy, Stoneham, MA US
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20090191208 | Antibodies against flagellin and uses thereof - The present invention provides a novel class of monoclonal antibodies which have a high affinity, broad spectrum neutralizing reactivity to flagellin from various Gram-negative bacteria including, but not limited to, | 07-30-2009 |
20090208506 | Antibodies against flagellin and uses thereof - The present invention provides a novel class of monoclonal antibodies which have a high affinity, broad spectrum neutralizing reactivity to flagellin from various Gram-negative bacteria including, but not limited to, | 08-20-2009 |
20100239583 | ANTIBODIES AGAINST FLAGELLIN AND USES THEREOF - The present invention provides a novel class of monoclonal antibodies which have a high affinity, broad spectrum neutralizing reactivity to flagellin from various Gram-negative bacteria including, but not limited to, | 09-23-2010 |
Kartik Murthy, Seattle, WA US
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20130073621 | ENFORCING COMMUNICATION POLICY RULES ON SHARED DOCUMENTS - A system is provided for automatically enforcing communication policy rules for document sharing between a communication server and a publishing server. The system may enable a policy agent to examine a communication containing a document attachment before the communication may be delivered to a recipient. The policy agent may evaluate the communication against communication policy rules, and if the policy agent determines that the communication policy rules are not violated, then a document upload agent may transfer the attached document to the publishing server. The system may then deliver the communication message to the recipient. If the policy agent determines that the communication policy rules are violated, then the system may prevent the document upload agent from transferring the attached document to the publishing server and may continue to deliver the communication to the recipient without the document attachment. | 03-21-2013 |
Kartik S. Murthy, Seattle, WA US
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20120284357 | CLIENT CALCULATION OF LINKS TO NETWORK LOCATIONS OF FILES TO UPLOAD - A link to a file to be stored at a network location is calculated using a client before the file is uploaded to the network location. The client may calculate the link to the network location either while online or offline. In response to determining to upload a file, a link to the file at the network location is calculated before uploading the file. The created link may be a direct link that specifies the file at the network location as the destination of the link and/or a redirect link that when used redirects the user to the file at the network location. The link may be created using various information (e.g. a default location, filename, and/or a unique key). When online, the client may reserve a specific link with the network location before the file is uploaded. | 11-08-2012 |
20130254710 | STACKS FOR CONTENT ORGANIZATION - Stacks that associate different electronic content are created using tags that are associated with electronic content. Stacks may be personal, organizational and/or shared. A tag may be associated with different types of electronic content (e.g. documents, people, contacts, meetings, emails, . . . ) that may be stored in different locations. The tag acts as an identifier that travels with the content as the electronic content is used. Content may be automatically/manually tagged. As the tagged content is used, the different applications that interact with the content (e.g. a messaging application, a content application) can use the tag to perform different actions. Changes to content with a tag may be aggregated such that users looking at the “consolidated” view can see all changes made to content or activity related to that content. | 09-26-2013 |
Mahesh Murthy, Newark, DE US
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20090324929 | Composite Membrane and Moisture Adjustment Module Using Same - A composite membrane and moisture adjustment module using the same is disclosed. The composite membrane includes a moisture-permeable resin layer interposed between porous membranes that constitute a pair; and the mean thickness of the moisture-permeable resin layer is 5 μm or less. | 12-31-2009 |
20100230277 | Capacitive Deionization Cell With Balanced Electrodes - A capacitive deionization cell comprising a first electrode, an anion membrane adjacent said first electrode forming an anion membrane-electrode conjugate, a cation membrane in spacial relation with said anion membrane defining a fluid flow path between said anion membrane and said cation membrane, and a second electrode adjacent said cation membrane forming a cation membrane-electrode conjugate, wherein said anion membrane-electrode conjugate and said cation membrane-electrode conjugate each have an effective capacitance, and the ratio of the effective capacitance of said cation membrane-electrode conjugate to the effective capacitance of said anion membrane-electrode conjugate is a non-zero number less than 2. | 09-16-2010 |
Manu Murthy, Chicago, IL US
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20100050621 | Machine control system having hydraulic warmup procedure - A control system for a machine is disclosed. The control system may have a pump, a low pressure reservoir, and at least one actuator connected to receive fluid pressurized by the pump and discharge fluid to the low pressure reservoir. The control system may also have a bypass passage situated to allow fluid to bypass the at least one actuator, and a warmup valve disposed within the bypass passage and being movable between a flow-passing position and a flow-blocking position. The control system may further have a hydraulic temperature sensor configured to generate a signal indicative of a temperature of the fluid, and a controller in communication with the pump, the warmup valve, and the hydraulic temperature sensor. The controller may be configured to move the warmup valve to the flow-passing position, fix a displacement position of the pump, and adjust an input speed of the pump in response to the signal. | 03-04-2010 |
Muki Murthy, Sammamish, WA US
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20080201780 | Risk-Based Vulnerability Assessment, Remediation and Network Access Protection - A system administrator may define a vulnerability and vulnerability setting for the client machine and may associate a level of risk with the vulnerability. The client may assess the level of risk associated with the vulnerability setting on the client machine and may report data regarding the level of risk to the system administrator. | 08-21-2008 |
Mukunda Murthy, Sammamish, WA US
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20080244071 | Policy definition using a plurality of configuration items - Policy definition using a plurality of configuration items is described. In one or more implementations, a plurality of policies is defined, each having a different combination of a plurality of configuration items. The policies are then implemented such that each of the clients is provided a respective amount of access to one or more resources based on compliance with applicable policies. | 10-02-2008 |
Narasimha Murthy, East Windsor, NJ US
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20090259664 | Infrastructure and Architecture for Development and Execution of Predictive Models - A system that enables development and execution of predictive models comprises a centralized data management system, a data extraction tool a model validation tool and a model execution tool. In embodiments, a data management system includes a data management server that can be accessed via a web browser that stores data in the form of a flat file. An extraction tool extracts data. A model validation tool validates a model by scoring an analytical environment data set and a production environment data set. A model execution tool allows a user to select when and how often a model is scored. | 10-15-2009 |
20090259685 | Infrastructure and Architecture for Development and Execution of Predictive Models - A system that enables development and execution of predictive models comprises a centralized data management system, a data extraction tool a model validation tool and a model execution tool. In embodiments, a data management system includes a data management server that can be accessed via a web browser that stores data. An extraction tool includes a data filter adapted to filter data based on, for example, a population criteria, a sample size, and a date range criteria. A model validation tool validates the model. A model execution tool allows a user to score the model. | 10-15-2009 |
20110196818 | INFRASTRUCTURE AND ARCHITECTURE FOR DEVELOPMENT AND EXECUTION OF PREDICTIVE MODELS - A system that enables development and execution of predictive models comprises a centralized data management system, a data extraction tool a model validation tool and a model execution tool. In embodiments, a data management system includes a data management server that can be accessed via a web browser that stores data. An extraction tool includes a data filter adapted to filter data based on, for example, a population criteria, a sample size, and a date range criteria. A model validation tool validates the model. A model execution tool allows a user to score the model. | 08-11-2011 |
20120265720 | INFRASTRUCTURE AND ARCHITECTURE FOR DEVELOPMENT AND EXECUTION OF PREDICTIVE MODELS - A system that enables development and execution of predictive models comprises a centralized data management system, a data extraction tool a model validation tool and a model execution tool. In embodiments, a data management system includes a data management server that can be accessed via a web browser that stores data. An extraction tool includes a data filter adapted to filter data based on, for example, a population criteria, a sample size, and a date range criteria. A model validation tool validates the model. A model execution tool allows a user to score the model. | 10-18-2012 |
20130091148 | INFRASTRUCTURE AND ARCHITECTURE FOR DEVELOPMENT AND EXECUTION OF PREDICTIVE MODELS - A system that enables development and execution of predictive models comprises a centralized data management system, a data extraction tool a model validation tool and a model execution tool. In embodiments, a data management system includes a data management server that can be accessed via a web browser that stores data in the form of a flat file. An extraction tool extracts data. A model validation tool validates a model by scoring an analytical environment data set and a production environment data set. A model execution tool allows a user to select when and how often a model is scored. | 04-11-2013 |
20130332232 | INFRASTRUCTURE AND ARCHITECTURE FOR DEVELOPMENT AND EXECUTION OF PREDICTIVE MODELS - A system that enables development and execution of predictive models comprises a centralized data management system, a data extraction tool a model validation tool and a model execution tool. In embodiments, a data management system includes a data management server that can be accessed via a web browser that stores data. An extraction tool includes a data filter adapted to filter data based on, for example, a population criteria, a sample size, and a date range criteria. A model validation tool validates the model. A model execution tool allows a user to score the model. | 12-12-2013 |
Narayan Krishna Murthy, Redmond, WA US
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20100299340 | DISTRIBUTED CONTACT INFORMATION DISCOVERY AND SHARING - A contact sharing system is described herein that allows multiple people to share their address books of contact information so that a person can search for contact information among the address books of the person's existing contacts in addition to any publicly available searchable sources of contact information. Because at least one of a person's contacts is likely to have contact information for the person or business that the person is trying to reach, searching the contacts of contacts is more likely to produce relevant search results than searching anonymous or public sources of contact information alone. Thus, the contact sharing system makes it easier for people to find contact information for people and businesses that they are trying to reach. | 11-25-2010 |
Nihal Murthy, Charlotte, NC US
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20110094834 | BRAKE CALIPER WITH BRAKE PAD TIMING AND RETRACTION CONTROLLER - A brake caliper is provided with a timing and retraction controller that that adjusts brake timing, eliminates parasitic brake losses and dampens out-of-plane vibration between the brake pad and rotor. The brake caliper includes a housing disposed over a brake rotor; first and second opposing brake pads extendably and retractably mounted on opposite sides of the caliper housing, brake pistons that extend and retract the brake pads into and out of frictional engagement with the rotor, and brake pad timing and retraction controllers disposed on opposite sides of the caliper housing. Each controller includes a Belleville spring or other resilient member with a short compression travel limited to between about 1.50 mm and 0.025 mm. The short stroke Belleville spring of each controller applies a hold-off force against the extension force of the brake pistons that slightly delays brake pad extension and slightly reduces brake pad clamping force against the rotor, thereby advantageously providing a front wheel braking bias when applied to the rear wheels of a vehicle. The restorative force applied by the short stroke Belleville forcefully and uniformly retracts the brake pad from the rotor, eliminating parasitic brake losses, and dampening out-of-plane vibration between the brake pad and rotor. | 04-28-2011 |
Niren Murthy, Seattle, WA US
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20100160216 | ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes (at physiologic pH, but can become active toward cell membranes if the environment is acidified below ca. pH 6.8), coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontopheresis, and/or electrophereis can also be used with the disrupting agents. | 06-24-2010 |
Niren Murthy, Atlanta, GA US
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20080199957 | ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontophoresis, and/or electrophoresis can also be used with the disrupting agents. | 08-21-2008 |
20090011993 | Novel strategies for delivery of active agents using micelles and particles - The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles. | 01-08-2009 |
20100062968 | Novel strategies for delivery of active agents using micelles and particles - The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles. | 03-11-2010 |
20100210504 | ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes (at physiologic pH, but can become active toward cell membranes if the environment is acidified below ca. pH 6.8), coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontopheresis, and/or electrophereis can also be used with the disrupting agents. | 08-19-2010 |
20110070166 | REDUCED DYE PROBES FOR THE DETECTION OF RADICAL OXYGEN SPECIES - Reduced dyes, such as hydrocyanines, deuterocyanines, and/or other deuterated dyes capable of detecting one or more reactive oxygen species are described herein. The reduced dyes exhibit little or no fluorescence due to the disrupted π conjugation. However, upon reaction with ROS, the reduced dyes are oxidized, regenerating the extended π conjugation and causing a substantial increase in fluorescence intensity. In many case, the oxidized dye is generally membrane impermeable. However, upon reduction, many of the reduced dyes are membrane permeable. Thus, reduced dyes can accumulate in cells and/or tissue to amplify the signal. Once inside the cell or tissue, the reduced dye is reoxidized upon reaction with ROS, and the oxidized dye again becomes membrane impermeable, trapping the dye within the cell. The reduced dyes can be used to image ROS, such as hydroxide radical and superoxide, in serum, cell cultures, tissue explants, and in vivo. | 03-24-2011 |
20110104293 | SYNERGISTIC INDUCTION OF HUMORAL AND CELLULAR IMMUNITY BY COMBINATORIAL ACTIVATION OF TOLL-LIKE RECEPTORS - Described herein are compositions that include a selected antigen, a TLR4 ligand and a TLR7/TLR8 ligand, wherein the antigen and TLR ligands are encapsulated in nanoparticles. Co-administration of both a TLR4 ligand and a TLR7/TLR8 ligand results in the synergistic induction of humor and cellular immunity as evidenced by an increase in pro-inflammatory cytokine production, an increase in the number of CD8 | 05-05-2011 |
20110288238 | ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontopheresis, and/or electrophoresis can also be used with the disrupting agents. | 11-24-2011 |
20120302575 | Methods for Preventing Oxidative Stress Injury of a Tissue by a Folate-Tempol Conjugate. - The present disclosure is generally related to methods of preventing oxidative stress injury induced by renal is-chemia-reperfusion by a Folate-TEMPOL conjugate. | 11-29-2012 |
20140105826 | REDUCED DYE PROBES FOR THE DETECTION OF RADICAL OXYGEN SPECIES - Reduced dyes, such as hydrocyanines, deuterocyanines, and/or other deuterated dyes capable of detecting one or more reactive oxygen species are described herein. The reduced dyes exhibit little or no fluorescence due to the disrupted π conjugation. However, upon reaction with ROS, the reduced dyes are oxidized, regenerating the extended π conjugation and causing a substantial increase in fluorescence intensity. In many case, the oxidized dye is generally membrane impermeable. However, upon reduction, many of the reduced dyes are membrane permeable. Thus, reduced dyes can accumulate in cells and/or tissue to amplify the signal. Once inside the cell or tissue, the reduced dye is reoxidized upon reaction with ROS, and the oxidized dye again becomes membrane impermeable, trapping the dye within the cell. The reduced dyes can be used to image ROS, such as hydroxide radical and superoxide, in serum, cell cultures, tissue explants, and in vivo. | 04-17-2014 |
20140171367 | Polymer Hydrogels For In Vivo Applications And Methods For Using And Preparing Same - Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated. | 06-19-2014 |
20140219950 | ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS - Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontophoresis, and/or electrophoresis can also be used with the disrupting agents. | 08-07-2014 |
Nitish K. Murthy, Allen, TX US
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20130089212 | Method and System for Hybrid Noise Cancellation - From a first microphone, first microphone signals are received that represent first sound waves. From a second microphone, second microphone signals are received that represent second sound waves. In response to the first microphone signals, analog processing is performed to estimate noise in the first sound waves, and first analog signals are generated for cancelling at least some of the estimated noise in the first sound waves. In response to the second microphone signals, digital processing is performed to estimate noise in the second sound waves, and digital information is generated for cancelling at least some of the estimated noise in the second sound waves. The digital information is converted into second analog signals that represent the digital information. The first and second analog signals are combined into third analog signals for cancelling at least some of the estimated noise in the first and second sound waves. | 04-11-2013 |
Nitish Krishna Murthy, Allen, TX US
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20130013304 | Method and Apparatus for Environmental Noise Compensation - A method of environmental noise compensation a speech audio signal is provided that includes estimating a fast audio energy level and a slow audio energy level in an audio environment, wherein the speech audio signal is not part of the audio environment, and applying a gain to the speech audio signal to generate an environment compensated speech audio signal, wherein the gain is updated based on the estimated slow audio energy level when the estimated fast audio energy level is not indicative of an audio event in the audio environment and the estimated gain is not updated when the estimated fast audio energy level is indicative an audio event in the audio environment. | 01-10-2013 |
20130156214 | Method and System for Active Noise Cancellation According to a Type of Noise - Microphone signals are received from a microphone. The microphone signals represent first sound waves. A determination is made about a type of noise that likely exists in the first sound waves. In response to the type of noise, cancellation signals are generated by filtering the microphone signals with at least one of: a first filter in response to the type of noise indicating that a first type of noise likely exists in the first sound waves; and a second filter in response to the type of noise indicating that a second type of noise likely exists in the first sound waves. In response to the cancellation signals, second sound waves are output from a speaker for cancelling at least some noise in the first sound waves. | 06-20-2013 |
20140112491 | Method and Apparatus for a Configurable Active Noise Canceller - A method and apparatus for active noise canceling. The method includes retrieving an input sample from at least one of a feedback or feedforward microphone digitized through the sigma-delta converter, retrieving the input sample and a related filter, wherein the filter is customized to the particular headset, outputting a filtered signal through a speaker without any interpolation and reducing order of CIC filters, and outputting a response sharply tapered down. | 04-24-2014 |
20150025878 | Dominant Speech Extraction in the Presence of Diffused and Directional Noise Sources - A method of dominant speech extraction is provided that includes acquiring a primary audio signal from a microphone and at least one additional audio signal from at least one additional microphone, wherein the acquired audio signals include speech and noise, decomposing each acquired audio signal into a low frequency sub-band signal and a high frequency sub-band signal, applying speech suppression beamforming to the low frequency sub-band signals to generate a reference channel having an estimate of noise in the low frequency sub-band signals, applying noise cancellation to the low frequency sub-band signal of the primary audio signal using the reference channel to generate a first signal having a low frequency estimate of the speech, applying noise suppression beamforming to the high frequency sub-band signals to generate a second signal having a high frequency estimate of the speech, and combining the first and second signals to generate a full-band audio signal. | 01-22-2015 |
20150040671 | STRUCTURAL HEALTH MONITORING SYSTEM AND METHOD - A method includes: transmitting, via a signal generator, an electrical driving signal, the electrical driving signal having a mean square error; transmitting, via a wave generating component, a Lamb wave, the Lamb wave having many different modes; estimating, via an estimating component, a propagation parameter associated with the Lamb wave; and estimating, via an estimating component, a thickness of a material. | 02-12-2015 |
Pawan Rajpanth Murthy, Powell, OH US
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20080222012 | System and method for advertising online vehicle sales - Vehicle information is provided by a private seller of a vehicle over a network to an online vehicle transaction server. A periodic payment amount is then calculated for the vehicle based on the provided vehicle information, as well as certain predetermined financing terms. In one embodiment a vehicle advertisement number is generated for the subject vehicle, and may serve as a identifier or online pointer to a webpage containing the subject vehicle's information, including the previously-calculated periodic payment amount. In embodiment, a vehicle advertisement document may be generating to include the vehicle advertisement number and the vehicle's sales price represented as the previously-calculated periodic payment amount. The advertisement document may be downloaded by the private vehicle seller and placed in the subject vehicle as a sale sign. | 09-11-2008 |
Pratap S. Murthy, Ann Arbor, MI US
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20120152187 | PUMP ACTUATOR ANTI-ROTATION DEVICE - A tappet having a contiguous body, an outer wall and transverse web. The outer wall defines a cylindrically-shaped outer surface and a recess. The recess is disposed within cylindrical surface of the body. An alignment member is press-fit between two staked ends of the recess, which engage opposite sides of the alignment member. The alignment member extends outwardly from the cylindrically-shaped surface. A roller is mounted to the contiguous body at the cam contacting end of the tappet. | 06-21-2012 |
Raghu Murthy, St. Joseph, MI US
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20110150609 | CRUCIBLE SHUTTLE ASSEMBLY AND METHOD OF OPERATION - A crucible handling shuttle includes a pair of opposed dual crucible-gripping arms mounted on a rotatable head. The shuttle is removably plugged into a sliding block of a carriage to move between a furnace and a crucible loading station. The carriage includes mechanical, electrical, and pneumatic plugs or sockets which couple to mating sockets or plugs of the shuttle. A linear actuator extends between the carriage and the furnace base to raise and lower the carriage and shuttle coupled thereto. | 06-23-2011 |
Rakesh Murthy, Arlington, TX US
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20100126297 | Microrobots with large actuation volumes, and controllers, systems, and methods - Robots, and atomic force microscopes including robots, that utilize in-plane actuators to provide large out-of-plane working volumes and forces. | 05-27-2010 |
20100145511 | Microcrawler and conveyor robots, controllers, systems, and methods - Robots, controllers, systems, and methods for microcrawler robots (e.g., with stick-slip gaited locomotion and/or with power multiplexing between actuators). | 06-10-2010 |
20140195094 | Microcrawler and Conveyor Robots, Controllers, Systems, and Methods - Robots, controllers, systems, and methods for microcrawler robots (e.g., with stick-slip gaited locomotion and/or with power multiplexing between actuators). | 07-10-2014 |
Ramana M. Murthy, Phoenix, AZ US
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20110153476 | SYSTEM AND METHOD FOR DETERMINING TAX LIABILITY IN RESPONSE TO A MOBILITY - A tax event system is configured to evaluate a taxable event that gives rise to tax liability in multiple jurisdictions. The system provides for real time determination of location information (e.g. work location, residence location, assignment location, and the like) for the calculation of tax liability. Such real time analysis allows for transactions to be settled and tax liability to be satisfied in time periods prescribed by various regulating authorities. | 06-23-2011 |
Sankarshan Murthy, Towson, MD US
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20100276168 | POWER TOOL WITH IMPACT MECHANISM - A power tool with a housing, a motor, a transmission, a spindle and an impact mechanism. The motor has an output shaft that drives the transmission. The transmission has a plurality of planet gears, a planet carrier journally supporting the planet gears for rotation about an axis, and a ring gear that is in meshing engagement with the planet gears. The impact mechanism has a plurality of anvil lugs, an impactor and an impactor spring. The anvil lugs are coupled to the ring gear and are not engaged by the planet gears. The impactor is mounted to pivot about the spindle and has a plurality of hammer lugs. The impactor spring biases the impactor toward the ring gear to cause the hammer lugs to engage the anvil lugs. A power tool having an impact mechanism with an external adjusting member that can be moved to vary a trip torque of the impact mechanism is also provided. | 11-04-2010 |
20110203821 | POWER SCREWDRIVER HAVING ROTARY INPUT CONTROL - A power tool includes an output shaft configured to rotate about a longitudinal axis, a motor drivably connected to the output shaft to impart rotary motions thereto, and a rotational motion sensor spatially separated from the output shaft and operable to determine the user-imparted rotational motion of the power tool with respect to the longitudinal axis. A controller is electrically connected to the rotational motion sensor and the motor. The controller determines angular velocity of the power tool about the axis, rotational displacement of the power tool about the axis, and/or a direction of the rotational displacement using input from the rotational motion sensor. The controller then controls the motor according to the angular velocity, the rotational displacement, and/or the direction of the rotational displacement. | 08-25-2011 |
20110278966 | Motor With Overmolded Permanent Magnets - A permanent magnet electric motor has a stator and a rotor. The stator has a stator housing with at least a North pole and a South pole. Each pole includes at least two permanent magnets arranged on an inner surface of the stator housing near the pole tips and an overmold of magnetic material molded around the permanent magnets and over the inner surface of the stator between the permanent magnets. Alternatively, an overmold of magnetic material may be provided over an inner surface of the stator, where the thickness of the overmold layer is greater near tips of each pole than in the middle portion of each pole. | 11-17-2011 |
20110298313 | Motor With Permanent Magnets and Method of Manufacturing Power Tool With Same - A permanent magnet electric motor has a stator and a rotor. The stator has a stator housing with at least a North pole and a South pole, each pole including permanent magnets affixed to an inner surface of the stator housing, where at least two of the magnets within a pole have dissimilar characteristics, e.g., different widths or different grades of demagnetization resistance. | 12-08-2011 |
20110303432 | POWER TOOL TRANSMISSION - A power tool that includes a housing assembly, a motor received in the housing assembly, a trigger, an output spindle, a transmission and a bearing. The transmission is received in the housing assembly and transmits rotary power between the motor and the output spindle. The transmission has an output planetary stage with an output planet carrier. The transmission also has a member that is axially movable between a first position, which causes the transmission to operate in a first speed ratio, and a second position in which the transmission operates in a second speed ratio that is different than the first speed ratio. The bearing is disposed radially between and engages both the housing assembly and the output planet carrier. The output spindle is at least partially received into the output planet carrier such that the bearing indirectly supports the output spindle. | 12-15-2011 |
20130126201 | Transmission for Power Tool with Variable Speed Ratio - A power tool includes a housing, a motor contained in the housing, an output shaft extending proximate a front of the housing, an end effector coupled to the output shaft and configured to hold an accessory; and a transmission disposed in the housing between the motor and the output shaft. The transmission includes a variable ratio gear set configured to transmit power from the motor to the output shaft at a substantially variable speed ratio. The transmission may further include a constant ratio gear set configured to transmit power from the motor at a substantially constant speed ratio. The transmission may be automatically or manually shiftable between a first mode where it transmits power through the constant speed ratio gear set and a second mode where it transmits power through the variable speed ratio gear set. | 05-23-2013 |
Sankarshan Murthy, Cockeysville, MD US
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20100033036 | Motor With Permanent Magnets and Method of Manufacturing; Power Tool With Same - An electric motor has a rotor and a stator. The rotor or the stator has arced permanent magnets that have essentially the same inner radius (IR) and outer radius (OR). In an aspect, the stator has a stator housing having a plurality of poles. Each pole includes a plurality of flat magnets affixed to an inner surface of the stator housing. In an aspect, flats on the outside of the stator housing key the stator assembly in a power tool housing. In an aspect, flat magnets are pre-magnetized, pre-assembled with alternating magnetic polarities, inserted into a stator housing, and remagnetized to a final, desired magnetic polarity configuration. In an aspect, pre-magnetized magnets and unmagnetized magnets are pre-assembled with unmagnetized magnets between magnetized magnets, the pre-assembled magnets inserted into a stator housing, and the unmagnetized magnets magnetized to a final, desired magnetic polarity configuration. In an aspect, pre-magnetized magnets are inserted between anchors inwardly extending from an inner surface of a stator housing with the anchors retaining each magnet placed in the stator housing between anchors from being angularly displaced by subsequently inserted magnets. In an aspect, pre-magnetized magnets are inserted in recesses in an inner surface of a stator housing with the recesses retaining each magnet placed in the stator housing between anchors from being angularly displaced by subsequently inserted magnets. In an aspect, each pole has at least three magnets, at least one of the magnets being thinner than the other magnets. In an aspect, the outer most magnets are made of magnetic material that is more resistant to demagnetization than at least one of the other magnets. In an aspect, the magnets of each pole are unevenly spaced over the pole In an aspect, a power tool includes such an electric motor. | 02-11-2010 |
20110152029 | HYBRID IMPACT TOOL WITH TWO-SPEED TRANSMISSION - A power tool that includes a housing, a motor, a planetary transmission, a first bearing and a second bearing. The motor is disposed in the housing and includes an output shaft. The planetary transmission has a sun gear, a plurality of first planet gears, a first ring gear and a carrier. The sun gear is driven by the output shaft. The first planet gears are driven by the sun gear and have teeth that are meshingly engaged to teeth of the first ring gear. The carrier includes a rear carrier plate and a front carrier plate between which the first and second planet gears are received. The rear carrier plate includes a first bearing aperture. The first bearing is received in the first bearing aperture and is configured to support the output shaft. The second bearing is received onto the rear carrier plate to support the carrier relative to the housing. | 06-23-2011 |
20110232930 | SPINDLE BEARING ARRANGEMENT FOR A POWER TOOL - A power tool with a motor, a housing, a transmission, an output spindle, a front bearing and a rear bearing. The motor has an output shaft. The transmission is disposed in the housing and receives a rotary input from the output shaft. The transmission includes an input planetary stage, which has an input planet carrier, and an output planetary stage. The output spindle is driven by the transmission and has a first end, which extends at least partly through the input planetary stage, and a second end opposite the first end. The front bearing is disposed between the output spindle and the housing to support the second end of the output spindle for rotation about the spindle axis. The rear bearing indirectly supports the first end of the output spindle in the housing for rotation about the spindle axis. | 09-29-2011 |
Sankarshan N. Murthy, Cockeysville, MD US
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20100071923 | HYBRID IMPACT TOOL - A power tool having a rotary impact mechanism and a mode change mechanism. The impact mechanism is driven by an output member of a transmission and includes a hammer and an anvil. The mode change mechanism includes a mode collar that is movable between a first position, in which the mode collar directly couples the hammer to the transmission output member to inhibit movement of the hammer relative to the spindle, and a second position in which the mode collar does not inhibit movement of the hammer relative to the spindle. A power tool having an impact mechanism with an external adjusting member that can be moved to vary a trip torque of the impact mechanism is also provided. | 03-25-2010 |
Sankarshan N. Murthy, Towson, MD US
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20130306341 | HYBRID IMPACT TOOL - A power tool having a rotary impact mechanism and a mode change mechanism. The impact mechanism is driven by an output member of a transmission and includes a hammer and an anvil. The mode change mechanism includes a mode collar that is movable between a first position, in which the mode collar directly couples the hammer to the transmission output member to inhibit movement of the hammer relative to the spindle, and a second position in which the mode collar does not inhibit movement of the hammer relative to the spindle. | 11-21-2013 |
Saravana Radha Krishna Murthy, Rockville, MD US
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20110152355 | METHOD FOR PREDICTING AND DETECTING TUMOR METASTASIS - The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-ΔN, and inhibitors of CPE-ΔN and compositions thereof. | 06-23-2011 |
20150031744 | METHOD FOR PREDICTING AND DETECTING TUMOR METASTASIS - The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-ΔN, and inhibitors of CPE-ΔN and compositions thereof. | 01-29-2015 |
Sechashayee S. Murthy, Yorktown Heights, NY US
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20120011316 | INTELLIGENT STORAGE PROVISIONING WITHIN A CLUSTERED COMPUTING ENVIRONMENT - Embodiments of the present invention provide an approach for intelligent storage planning and planning within a clustered computing environment (e.g., a cloud computing environment). Specifically, embodiments of the present invention will first determine/identify a set of storage area network volume controllers (SVCs) that is accessible from a host that has submitted a request for access to storage. Thereafter, a set of managed disk (mdisk) groups (i.e., corresponding to the set of SVCs) that are candidates for satisfying the request will be determined. This set of mdisk groups will then be filtered based on available space therein, a set of user/requester preferences, and optionally, a set of performance characteristics. Then, a particular mdisk group will be selected from the set of mdisk groups based on the filtering. | 01-12-2012 |
Seshashayee Murthy, Yorktown Heights, NY US
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20110153507 | SYSTEM, METHOD, AND APPARATUS FOR SERVER-STORAGE-NETWORK OPTIMIZATION FOR APPLICATION SERVICE LEVEL AGREEMENTS - A computer-implemented method for determining, from a system including a plurality of data center resources, at least one configuration of data center resources for an implementation of an application. The method includes receiving application information and receiving information regarding known internal features up the data center resources. The method also includes provisioning the system of data center resources and creating possible configurations of data center resources for implementing application. The method also includes correlating models and data center resources to create an interrelated representation of the models and the data center resources. The models predict a relationship of parameters for the possible configurations. The method also includes creating a multiple dimensional analysis of parameters for the possible configurations of data center resources using the interrelated representation and selecting a configuration of data center resources from the possible configurations using the multiple dimensional analysis of parameters. | 06-23-2011 |
Seshashayee S. Murthy, Somers, NY US
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20110022879 | AUTOMATED DISASTER RECOVERY PLANNING - A system and associated method for automated disaster recovery (DR) planning. A DR planning process receives disaster recovery requirements and a target environment configuration from a user to design DR plans for the target environment configuration that meets disaster recovery requirements. The DR planning process accesses a knowledgebase containing information on replication technologies, best practice recipes, and past deployment instances. The DR planning process creates the DR plans by analyzing the disaster recovery requirements into element risks, associating replication technologies to protect each element risks, combining associated replication technologies based on the best practice recipes, and selecting highly evaluated combination based on the past deployment instances. The DR planning process presents the DR plans as classified by replication strategy-architecture combination for each DR plans and marks how strongly each DR plans are recommended. | 01-27-2011 |
20110055621 | DATA REPLICATION BASED ON CAPACITY OPTIMIZATION - A system and associated method for replicating data based on capacity optimization. A local node receives the data associated with a key. The local node within a local domain communicates with nodes of remote domains in a system through a communication network. Each domain has its own distributed hash table that partitions key space and assigns a certain key range to an owner node within the domain. For new data, the local node queries owner nodes of domains in the system progressively from the local domain to remote domains for a duplicate of the new data. Depending on a result returned by owner nodes and factors for replication strategies, the local node determines a replication strategy and records the new data in the local node pursuant to the replication strategy. | 03-03-2011 |
Seshashayee S. Murthy, Yorktown Heights, NY US
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20110138391 | CONTINUOUS OPTIMIZATION OF ARCHIVE MANAGEMENT SCHEDULING BY USE OF INTEGRATED CONTENT-RESOURCE ANALYTIC MODEL - A system and associated method for continuously optimizing data archive management scheduling. A job scheduler receives, from an archive management system, inputs of task information, replica placement data, infrastructure topology data, and resource performance data. The job scheduler models a flow network that represents data content, software programs, physical devices, and communication capacity of the archive management system in various levels of vertices according to the received inputs. An optimal path in the modeled flow network is computed as an initial schedule, and the archive management system performs tasks according to the initial schedule. The operations of scheduled tasks are monitored and the job scheduler produces a new schedule based on feedbacks of the monitored operations and predefined heuristics. | 06-09-2011 |
20110213508 | OPTIMIZING POWER CONSUMPTION BY DYNAMIC WORKLOAD ADJUSTMENT - A system and associated method for optimizing power consumption of a data center by dynamic workload adjustment. A current workload distribution of the data center is shifted to an optimal workload solution that provides acceptable level of service with the least amount of power consumption. The sum of power cost and migration cost that corresponds to the optimal workload solution is the lowest among all sums that correspond to respective candidate workload solutions. The power cost is determined by a maximum temperature of the data center and accompanying cooling cost for each candidate workload solution. The migration cost is determined by performance degradation that occurs during shifting a workload distribution of the data center from the current workload distribution to each candidate workload solution. | 09-01-2011 |
20110231541 | SYSTEM AND METHOD FOR A STORAGE AREA NETWORK VIRTUALIZATION OPTIMIZATION - A method is implemented in a computer infrastructure having computer executable code tangibly embodied on a computer readable storage medium having programming instructions. The programming instructions are operable to determine one or more optimal mappings between a server layer and a storage layer through a network layer based on performance metrics of one or more ports of at least one of the server layer, the storage layer and the network layer. | 09-22-2011 |
20110314164 | INTELLIGENT NETWORK STORAGE PLANNING WITHIN A CLUSTERED COMPUTING ENVIRONMENT - Embodiments of the present invention provide an integrated host and subsystem port selection methodology that uses performance measurements combined with information about active data paths. This technique also helps in resilient fabric planning by selecting ports from redundant fabrics. In a typical embodiment, host port to storage port pairs that create a path between a host and a storage device will be identified. From these pairs, a set of host port to storage port candidates for communicate data from the host to the storage device will be identified based on a set of resiliency constraints. Then, a specific host port to storage port pair will be selected from the set based on a lowest joint workload measurement. A path will then be created between the specific host port and storage port, and data will be communicated from the host to the storage device via the path. | 12-22-2011 |
20120042061 | CALIBRATING CLOUD COMPUTING ENVIRONMENTS - In general, embodiments of present invention provide an approach for calibrating a cloud computing environment. Specifically, embodiments of the present invention provide an empirical approach for obtaining end-to-end performance characteristics for workloads in the cloud computing environment (hereinafter the “environment”). In a typical embodiment, different combinations of cloud server(s) and cloud storage unit(s) are determined. Then, a virtual machine is deployed to one or more of the servers within the cloud computing environment. The virtual machine is used to generate a desired workload on a set of servers within the environment. Thereafter, performance measurements for each of the different combinations under the desired workload will be taken. Among other things, the performance measurements indicate a connection quality between the set of servers and the set of storage units, and are used in calibrating the cloud computing environment to determine future workload placement. Along these lines, the performance measurements can be populated into a table or the like, and a dynamic map of a data center having the set of storage units can be generated. | 02-16-2012 |
20120047265 | PERFORMANCE ISOLATION FOR STORAGE CLOUDS - Embodiments of the present invention provide performance isolation for storage clouds. Under one embodiment, workloads across a storage cloud architecture are grouped into clusters based on administrator or system input. A performance isolation domain is then created for each of the clusters, with each of the performance isolation domains comprising a set of data stores associated with a set of storage subsystems and a set of data paths that connect the set of data stores to a set of clients. Thereafter, performance isolation is provided among a set of layers of the performance isolation domains. Such performance isolation is provided by (among other things): pooling data stores from separate performance isolation domains into separate pools; assigning the pools to device adapters, RAID controller, and the set of storage subsystems; preventing workloads on the device adapters from exceeding capacities of the device adapters; mapping the set of data stores to a set of Input/Output (I/O) servers based on an I/O capacity and I/O load of the set of I/O servers; and/or pairing ports of the set of I/O servers with ports of the set of storage subsystems, the pairing being based upon availability, connectivity, I/O load, and I/O capacity. | 02-23-2012 |
20120079097 | PROACTIVE IDENTIFICATION OF HOTSPOTS IN A CLOUD COMPUTING ENVIRONMENT - The present invention proactively identifies hotspots in a cloud computing environment through cloud resource usage models that use workload parameters as inputs. In some embodiments the cloud resource usage models are based upon performance data from cloud resources and time series based workload trend models. Hotspots may occur and can be detected at any layer of the cloud computing environment, including the server, storage, and network level. In a typical embodiment, parameters for a workload are identified in the cloud computing environment and inputted into a cloud resource usage model. The model is run with the inputted workload parameters to identify potential hotspots, and resources are then provisioned for the workload so as to avoid these hotspots. | 03-29-2012 |
20120116743 | OPTIMIZING STORAGE CLOUD ENVIRONMENTS THROUGH ADAPTIVE STATISTICAL MODELING - Embodiments of the present invention provide an approach for adapting an information extraction middleware for a clustered computing environment (e.g., a cloud environment) by creating and managing a set of statistical models generated from performance statistics of operating devices within the clustered computing environment. This approach takes into account the required accuracy in modeling, including computation cost of modeling, to pick the best modeling solution at a given point in time. When higher accuracy is desired (e.g., nearing workload saturation), the approach adapts to use an appropriate modeling algorithm. Adapting statistical models to the data characteristics ensures optimal accuracy with minimal computation time and resources for modeling. This approach provides intelligent selective refinement of models using accuracy-based and operating probability-based triggers to optimize the clustered computing environment, i.e., maximize accuracy and minimize computation time. | 05-10-2012 |
20120221745 | SYSTEM AND METHOD FOR A STORAGE AREA NETWORK VIRTUALIZATION OPTIMIZATION - A method is implemented in a computer infrastructure having computer executable code tangibly embodied on a computer readable storage medium having programming instructions. The programming instructions are operable to determine one or more optimal mappings between a server layer and a storage layer through a network layer based on performance metrics of one or more ports of at least one of the server layer, the storage layer and the network layer. | 08-30-2012 |
20120304182 | CONTINUOUS OPTIMIZATION OF ARCHIVE MANAGEMENT SCHEDULING BY USE OF INTEGRATED CONTENT-RESOURCE ANALYTIC MODEL - A system and associated method for continuously optimizing data archive management scheduling. A job scheduler receives, from an archive management system, inputs of task information, replica placement data, infrastructure topology data, and resource performance data. The job scheduler models a flow network that represents data content, software programs, physical devices, and communication capacity of the archive management system in various levels of vertices according to the received inputs. An optimal path in the modeled flow network is computed as an initial schedule, and the archive management system performs tasks according to the initial schedule. The operations of scheduled tasks are monitored and the job scheduler produces a new schedule based on feedbacks of the monitored operations and predefined heuristics. | 11-29-2012 |
20130179537 | TRANSMITTING OF CONFIGURATION ITEMS WITHIN A NETWORK - A method, system and program product for transmitting configuration item data by a network object within a network. The steps include the network object detecting a change; the network object detecting an amount of traffic within the network; the network object transmitting configuration item data to the network at a level based on the amount of traffic present within the network. If all of the configuration item data was not sent and the network object detects that the amount of network traffic within the network is below a determined amount, the network object transmits remaining configuration item data to the network; and if all configuration item data was sent, returns to the step of the network object detecting a change. | 07-11-2013 |
20130261826 | OPTIMIZING POWER CONSUMPTION BY DYNAMIC WORKLOAD ADJUSTMENT - A method and system for optimizing power consumption of a data center by dynamic workload adjustment. At least one candidate workload solution for the data center is generated. Each candidate workload solution represents a respective application map that specifies a respective workload distribution among application programs of the data center. Workload of the data center is dynamically adjusted from a current workload distribution to an optimal workload solution. The optimal workload solution is a candidate workload solution of the at least one candidate workload solution having a lowest sum of a respective power cost and a respective migration cost. Dynamically adjusting the workload of the data center includes: estimating a respective overall cost of each candidate workload solution, selecting the optimal workload solution that has a lowest overall cost as determined from the estimating, and transferring the optimal workload solution to devices of a computer system for deployment. | 10-03-2013 |
20130282910 | INTELLIGENT STORAGE PROVISIONING WITHIN A CLUSTERED COMPUTING ENVIRONMENT - Embodiments of the present invention provide an approach for intelligent storage planning and planning within a clustered computing environment (e.g., a cloud computing environment). Specifically, embodiments of the present invention will first determine/identify a set of storage area network volume controllers (SVCs) that is accessible from a host that has submitted a request for access to storage. Thereafter, a set of managed disk (mdisk) groups (i.e., corresponding to the set of SVCs) that are candidates for satisfying the request will be determined. This set of mdisk groups will then be filtered based on available space therein, a set of user/requester preferences, and optionally, a set of performance characteristics. Then, a particular mdisk group will be selected from the set of mdisk groups based on the filtering. | 10-24-2013 |
20130298131 | CONTINUOUS OPTIMIZATION OF ARCHIVE MANAGEMENT SCHEDULING BY USE OF INTEGRATED CONTENT-RESOURCE ANALYTIC MODEL - A method and associated system for continuously optimizing data archive management scheduling. A flow network is modeled. The flow network represents data content, software programs, physical devices, and communication capacity of the archive management system in various levels of vertices such that an optimal path in the flow network from a task of at least one archive management task to a worker program of the archive management system represents an optimal initial schedule for the worker program to perform the task. | 11-07-2013 |
20130333000 | SYSTEM AND METHOD FOR A STORAGE AREA NETWORK VIRTUALIZATION OPTIMIZATION - A method is implemented in a computer infrastructure having computer executable code tangibly embodied on a computer readable storage medium having programming instructions. The programming instructions are operable to determine one or more optimal mappings between a server layer and a storage layer through a network layer based on performance metrics of one or more ports of at least one of the server layer, the storage layer and the network layer. | 12-12-2013 |
Seshashayee Sankarshana Murthy, Somers, NY US
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20110010343 | OPTIMIZATION AND STAGING METHOD AND SYSTEM - An optimization method and system. The method includes receiving by a computing system a data footprint associated with data and a human resource model. The data footprint comprises a primary data section, a secondary data section, and an archive data section. A plurality of data storage strategies are associated with the primary data section, said secondary data section, and said archive data section. The plurality of data storage strategies are compared to each other. A data staging orchestrator software module is executed. The computing system determines based on results of executing the data staging orchestrator software module, an optimal migration time, an optimal migration speed, and an optimal migration cost for managing storage for portions of the data. The computing system executes a risk modulation software module and determines a risk associated with the managing. | 01-13-2011 |
20120191661 | OPTIMIZATION AND STAGING - An optimization method and system. The method includes receiving by a computing system a data footprint associated with data and a human resource model. The data footprint comprises a primary data section, a secondary data section, and an archive data section. A plurality of data storage strategies are associated with the primary data section, said secondary data section, and said archive data section. The plurality of data storage strategies are compared to each other. A data staging orchestrator software module is executed. The computing system determines based on results of executing the data staging orchestrator software module, an optimal migration time, an optimal migration speed, and an optimal migration cost for managing storage for portions of the data. The computing system executes a risk modulation software module and determines a risk associated with the managing. | 07-26-2012 |
Seshashayee Sankarshana Murthy, Yorktown Heights, NY US
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20100211956 | METHOD AND SYSTEM FOR CONTINUOUS OPTIMIZATION OF DATA CENTERS BY COMBINING SERVER AND STORAGE VIRTUALIZATION - The invention provides a method and system for continuous optimization of a data center. The method includes monitoring loads of storage modules, server modules and switch modules in the data center, detecting an overload condition upon a load exceeding a load threshold, combining server and storage virtualization to address storage overloads by planning allocation migration between the storage modules, to address server overloads by planning allocation migration between the server modules, to address switch overloads by planning allocation migration mix between server modules and storage modules for overload reduction, and orchestrating the planned allocation migration to reduce the overload condition in the data center. | 08-19-2010 |
20110167424 | INTEGRATED DIFFERENTIATED OPERATION THROTTLING - A method and system for throttling a plurality of operations of a plurality of applications that share a plurality of resources. A difference between observed and predicted workloads is computed. If the difference does not exceed a threshold, a multi-strategy finder operates in normal mode and applies a recursive greedy pruning process with a look-back and look-forward optimization to select actions for a final schedule of actions that improve the utility of a data storage system. If the difference exceeds the threshold, the multi-strategy finder operates in unexpected mode and applies a defensive action selection process to select actions for the final schedule. The selected actions are performed according to the final schedule and include throttling of a CPU, network, and/or storage. | 07-07-2011 |
Shashi K. Murthy, Newton, MA US
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20140057280 | METHODS AND COMPOSITIONS FOR HIGHLY SPECIFIC CAPTURE AND RELEASE OF BIOLOGICAL MATERIALS - Disclosed herein are hydrogel compositions and methods of making hydrogel compositions. Furthermore, methods of specifically capturing and releasing biological materials from a sample using the disclosed hydrogel compositions are disclosed, including methods of utilizing the compositions in microfluidic devices. | 02-27-2014 |
20140065688 | METHODS AND COMPOSITIONS FOR MAGNETOPHORETIC SEPARATION OF BIOLOGICAL MATERIALS - Disclosed herein are devices for the magnetophoretic separation of target biological materials including a separation chamber that has a plurality of channels, and one or more wires carrying a current, the wires generating a magnetic force that deflects magnetically-labeled target biological materials into a buffer stream. In addition, methods of separating target biological materials from non-target biological materials in a sample are disclosed. Finally, methods for constructing a magnetophoretic separation device are disclosed. | 03-06-2014 |
Shreedhar Rajpanth Murthy, Cincinnati, OH US
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20110196330 | ABSORBENT ARTICLE COMPRISING FLUID HANDLING ZONES - An absorbent article comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet. The absorbent article comprises a first fluid handling zone having a first Transverse Fluid Travel Distance and a second fluid handling zone having a second Transverse Fluid Travel Distance. The first Transverse Fluid Travel Distance is at least about 50% greater than said second Transverse Fluid Travel Distance, which results in an absorbent article that is better able to handle bodily fluids and reduce the risk of accidental leakage of bodily fluids onto a consumer's undergarments. | 08-11-2011 |
20140031779 | ABSORBENT ARTICLE COMPRISING FLUID HANDLING ZONES - An absorbent article comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet. The absorbent article comprises a first fluid handling zone having a first Transverse Fluid Travel Distance and a second fluid handling zone having a second Transverse Fluid Travel Distance. The first Transverse Fluid Travel Distance is at least about 50% greater than said second Transverse Fluid Travel Distance, which results in an absorbent article that is better able to handle bodily fluids and reduce the risk of accidental leakage of bodily fluids onto a consumer's undergarments. | 01-30-2014 |
Shridhara C. Murthy, Ann Arbor, MI US
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20090246829 | SEQUENCE ANALYSIS OF THE TETRAVALENT ROTAVIRUS VACCINE - Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus:human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules. | 10-01-2009 |
Sohan Rajpanth Murthy, Cincinnati, OH US
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20100240569 | STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE SORBITOL ACETAL DERIVATIVES - Fluid detergent compositions comprising from about 0.01% to about 1% by weight of an external structurant comprising dibenzylidene sorbitol acetal derivatives for providing desired rheological benefits such as product thickening, shear thinning behavior, as well as particle suspension capabilities. | 09-23-2010 |
20100240571 | STRUCTURED FLUID DETERGENT COMPOSITIONS COMPRISING DIBENZYLIDENE POLYOL ACETAL DERIVATIVES AND DETERSIVE ENZYMES - Fluid detergent compositions comprising an external structurant comprising dibenzylidene polyol acetal derivatives for providing desired rheological benefits such as product thickening, shear thinning behavior, as well as particle suspension capabilities, and a detersive enzyme such as lipase. | 09-23-2010 |
Sreekant Murthy, Sewell, NJ US
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20100130367 | Methods of Quantitatively Assessing Inflammation with Biosensing Nanoparticles - The present invention includes a method of using one or more biomarkers to identify individuals with inflammatory disease using Quantum Dots conjugated to targeting moieties that will specifically bind to biomarker proteins or nucleic acids encoding the biomarker, where detection of the biomarker is associated with the inflammatory disease. | 05-27-2010 |
20120253265 | METHODS AND DEVICES FOR THE TREATMENT AND PREVENTION OF MALIGNANCY IN ENTERIC DISEASES USING NON-THERMAL PLASMA - Non-thermal plasma is a partly ionized gas, which can be generated by a high-voltage electric field at a low pressure. Disclosed herein are apparatuses and methods for treating an enteric disease in vivo using non-thermal plasma. The disclosed apparatuses have a first conduit comprising a lumen and a tip; a first electrode disposed within the lumen of the first conduit; a second electrode comprised of a metal conduit disposed within the first conduit; an insulator disposed within the lumen of the first conduit, the insulator configured to electrically insulate the first electrode from the second electrode; and a gas channel disposed between the outer surface of the metal conduit and the inner surface of the first conduit, the gas channel being capable of feeding a gas from a gas source to the tip, wherein when the potential is applied, the gas is ionized to produce the non-thermal plasma. | 10-04-2012 |
20130034863 | Apparatus and Methods for Detecting Inflammation Using Quantum Dots - Apparatus and methods for detecting an a biomarker indicative of an inflammatory condition, including a capillary tube adapted for one or more biomarkers to adhere to an interior surface thereof, a light source for energizing quantum dots conjugated with the biomarkers within the capillary tube, and a detection system for detecting and quantifying fluorescent energy emitted by the quantum dots in one or more predetermined wavelength ranges, each wavelength range being correlated to one and only one of the biomarkers. A method of stabilizing the fluorescence intensity of quantum dots is also disclosed. | 02-07-2013 |
Srinivasa V. Murthy, Lewisville, NC US
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20110257168 | DERIVATIVES OF OXABISPIDINE AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS - The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 10-20-2011 |
20120309737 | 3,6-Diazabicyclo[3.1.1]heptanes as Neuronal Nicotinic Acetycholine Receptor Ligands - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 12-06-2012 |
20140288169 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS - The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for their use, and their pharmaceutical compositions. | 09-25-2014 |
20140315880 | 3,6-DIAZABICYCLO[3.1.1]HEPTAINES AS NEURONAL NICOTINIC ACETYCHOLINE RECEPTOR LIGANDS - The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 10-23-2014 |
20150080576 | SUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES - Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are amide compounds which can be prepared from certain heteroaryl carboxylic acids and certain diazabicycloalkanes. The compounds exhibit selectivity for, and bind with high affinity to, neuronal nicotinic receptors of the α4β2 subtype in the central nervous system (CNS). The compounds and compositions can be used to treat and/or prevent a wide variety of conditions or disorders, particularly CNS disorders. The compounds can: (i) alter the number of nicotinic cholinergic receptors of the brain of the patient, (ii) exhibit neuroprotective effects, and (iii) when employed in effective amounts, not result in appreciable adverse side effects (e.g. side effects such as significant increases in blood pressure and heart rate, significant negative effects upon the gastrointestinal tract, and significant effects upon skeletal muscle). | 03-19-2015 |
Srinivasa V. Murthy, Winston-Salem, NC US
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20100173968 | SUB-TYPE SELECTIVE AZABICYCLOALKANE DERIVATIVES - Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are amide, ketone, and ester compounds prepared from certain azabicycloalkane carboxylic acids. The resulting compounds exhibit selectivity for, and bind with high affinity to, neuronal nicotinic receptors of the α4β2 subtype in the central nervous system (CNS). The compounds and compositions can be used to treat and/or prevent a wide variety of conditions or disorders, such as those disorders characterized by dysfunction of nicotinic cholinergic neurotransmission, including disorders involving neuromodulation of neurotransmitter release, such as dopamine release. CNS disorders, which are characterized by an alteration in normal neurotransmitter release, are another example of disorders that can be treated and/or prevented. The compounds can: (i) alter the number of nicotinic cholinergic receptors of the brain of the patient, (ii) exhibit neuroprotective effects, and (iii) when employed in effective amounts, not result in appreciable adverse side effects (e.g. side effects such as significant increases in blood pressure and heart rate, significant negative effects upon the gastrointestinal tract, and significant effects upon skeletal muscle). | 07-08-2010 |
Sudhindra Murthy, Irving, TX US
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20110119714 | AUTOSCROLLING THROUGH INTERACTIVE TELEVISION CONTENT - A video client device receives a request for interactive television content. The video client device provides, in response to the request, the interactive television content for display on a video display device. The video client device receives an instruction to initiate an autoscroll function. The video client device retrieves, in response to the instruction, configuration information that identifies a manner for performing the autoscroll function. The video client device performs the autoscroll function to automatically scroll through the interactive television content, in a horizontal direction or a vertical direction, on the video display device based on the configuration information. | 05-19-2011 |
Sudhindra S. Murthy, Irving, TX US
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20110052146 | SYSTEMS AND METHODS FOR ENHANCING UTILIZATION OF RECORDED MEDIA CONTENT PROGRAMS - Exemplary systems and methods for enhancing utilization of recorded media content programs are disclosed. An exemplary method includes a media content processing system maintaining data representative of a recorded media content program in a data storage facility, accessing program highlights data for the recorded media content program, the program highlights data specifying a set of one or more select segments of the recorded media content program, and utilizing the program highlights data to access and play back the set of one or more select segments of the recorded media content program for experiencing by a user. In some examples, the end user has control of selection and playback of the set of one or more select segments of the recorded media content program. Corresponding systems and methods are also disclosed. | 03-03-2011 |
Sudhir N. Murthy, Washington, DC US
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20140069863 | METHOD AND APPARATUS FOR NITROGEN REMOVAL IN WASTEWATER TREATMENT - A reactor and control method thereof for nitrogen removal in wastewater treatment achieves a measured control of maintaining high ammonia oxidizing bacteria (AOB) oxidation rates while achieving nitrite oxidizing bacteria (NOB) repression, using various control strategies, including: 1) ammonia and the use of ammonia setpoints, 2) operational DO and the proper use of DO setpoints, 3) bioaugmentation of a lighter flocculant AOB fraction, and 4) proper implementation of transient anoxia within a wide range of reactor configurations and operating conditions. | 03-13-2014 |
20140069864 | METHOD AND APPARATUS FOR NITROGEN REMOVAL IN WASTEWATER TREATMENT - One or more reactor and one or more control methods are used for nitrogen removal in wastewater treatment to achieve measured control of maintaining high ammonia oxidizing bacteria (AOB) oxidation rates while achieving nitrite oxidizing bacteria (NOB) out-selection, using various control strategies, including: 1) ammonia and the use of ammonia setpoints; 2) operational DO and the use of DO setpoints; 3) bioaugmentation of anammox and lighter flocculant AOB fraction; and 4) implementation of transient anoxia in several reactor configurations and conditions for removal of oxidized nitrogen using anammox or heterotrophic organisms. Controls described maximize nitrogen removal with minimal aeration, through control of transient anoxia and aerobic SRT, out-selection of NOB, and control of DO concentrations or aeration interval by keeping the reactor ammonia (NH | 03-13-2014 |
Sudhir N. Murthy, Herndon, VA US
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20140083936 | METHOD AND APPARATUS FOR WATER TREATMENT USING SCREENS - An apparatus and method for selecting, retaining or bioaugmenting solids in an activated sludge process for improving wastewater treatment using screens. The screens can be used to separate and retain solids based on size, compressibility or shear resistance. The screens are used to separate and select slow growing organisms, faster settling organisms, or materials added to absorb, treat or remove constituents in the activated sludge process. A swapping screen arrangement provides another means of selecting various particles. The exposed shear rate or time, particle compression, or SRTs can be adjusted manually and/or automatically in response to detected readings from an instrument such as a spectrophotometer or other optical approaches to optimize selection of organisms. The present disclosure may be configured as an activated sludge system operated at different solids residence times (SRT) for different solids fractions allowing slow growing organisms to get established in competition with faster growing organisms or aggregates thereof. | 03-27-2014 |
20140131273 | METHOD AND APPARATUS FOR WASTEWATER TREATMENT USING SCREENS - An apparatus and method for selecting and retaining solids in an activated sludge process for the improving wastewater treatment using screens. The screens can be used to separate and retain solids based on size or compressibility. The screens are used to separate and select for slow growing organisms, faster settling organisms, or materials added to absorb, treat or remove constituents in the activated sludge process. | 05-15-2014 |
20140263041 | METHOD AND APPARATUS FOR MAXIMIZING NITROGEN REMOVAL FROM WASTEWATER - A reactor and control method for maximizing nitrogen removal and minimizing aeration requirements through control of transient anoxia and aerobic SRT, repression of NOB, and control of dynamic DO concentrations or aeration interval by keeping the reactor NH | 09-18-2014 |
Vasudeva Murthy, Rockville, MD US
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20120179836 | SYSTEM AND METHOD FOR PROCESSING, ASSIGNING, AND DISTRIBUTING ELECTRONIC REQUESTS - A system and method for processing and managing electronic requests is disclosed. The system may comprise an input module configured to receive a plurality of electronic requests associated with at least one of a product, service, order, and status. The system may comprise a classification module configured to assign each electronic request with at least one category. The system may comprise a transformation module configured to convert the plurality of electronic requests into a format compatible with one or more downstream systems. The system may comprise a distribution module configured to distribute the plurality of electronic requests based on routing rules to one or more downstream systems, wherein the one or more downstream systems responds to the at least one request. The system may comprise a management module configured to manage the plurality of electronic requests, wherein managing the plurality of electronic requests comprises receiving status notifications associated with the at least request from the one or more downstream systems. The system may also comprise a monitoring module configured to present, via a graphical user interface, information associated with at least one of the plurality of electronic requests to a user. | 07-12-2012 |
Vasudeva Sankarshana Murthy, Ann Arbor, MI US
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20110027040 | FASTENER ASSEMBLY - A fastener assembly for attaching a fastener to an opening of a sheet material is disclosed. The sheet material is typically located adjacent to a base structure and the fastener assembly affords radial movement of the fastener relative to the opening of the sheet material. The radial movement allows the fastener to be aligned with a desired location on the base structure, e.g. a threaded aperture—after being attached to the sheet material. In this manner, the fastener assembly provides for the placement of the fastener in difficult to reach and/or see locations until it can be attached to the base structure. | 02-03-2011 |
20120043792 | BUCKLE FOR CENTER OCCUPANT FOR BENCH SEAT WITH EXTENDED TRAVEL - A 60/40 bench seat is provided allowing for increased sliding travel along a set of tracks to allow for easier ingress and egress of a vehicle passenger accessing the rear of a bench seat. The 60/40 bench seat assembly allows for increased travel along the tracks without adding significant increases in assembly parts, cost, or weight. The 60/40 bench seat assembly is provided including a profile member and a buckle. The 60/40 bench seat assembly is divided into a 40% section seat and a 60% section seat. The 60/40 seat assembly further includes a profile member operable to push down the buckle to allow for increased travel of the 60% seat. The buckle includes a first surface and the profile includes a second surface contacting the buckle first surface thereby pushing the buckle towards a vehicle floor. | 02-23-2012 |
Vinay Mudinoor Murthy, Elmont, NY US
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20140191900 | METHOD AND APPARATUS FOR SIMULTANEOUS MULTI-MODE PROCESSING PERFORMING TARGET DETECTION AND TRACKING USING ALONG TRACK INTERFEROMETRY (ATI) AND SPACE-TIME ADAPTIVE PROCESSING (STAP) - The present invention discloses one or more methods to perform multimode processing using a single set of measured data in a multi-sensor fusion framework. In this context, various data processing methodologies are combined in parallel in a suitable manner to simultaneously image, detect, identify and track moving targets over clutter such as stationary background using data obtained from a single set of measurements. Traditionally multiple sets of data would be required to perform these tasks, furthermore the disparate datum would be processed independently of one another. By using a common data source and interconnected processors the information content of the measured data can be fully exploited and leveraged to provide actionable intelligence and aid logistics. | 07-10-2014 |
20140282035 | ON-DEMAND SIMULTANEOUS SYNTHETIC APERTURE RADAR (SAR) AND GROUND MOVING TARGET INDICATION (GMTI) USING MOBILE DEVICES - Methods and apparatus are provided for obtaining current geographic imagery and moving target geolocations and tracks from a typically autonomous remote platform device with sensors spanning the electromagnetic spectrum through a mobile device interface. An autonomous system is provided capable of interpreting high-level commands, measuring data using multiple sensors and processing the data to generate relevant data products which expedites the data measurement/processing procedure enabling field personnel to request and receive mission-critical intelligence in a timely manner. | 09-18-2014 |
Vinit S. Murthy, Houston, TX US
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20100222501 | SCALABLE PROCESS FOR SYNTHESIZING UNIFORMLY-SIZED COMPOSITE NANOPARTICLES - A method for making composite nanoparticles comprises a) providing an amount of a polyelectrolyte having a charge, b) providing an amount of a counterion having a valence of at least 2, the counterion having a charge opposite the charge of the polyelectrolyte, c) combining the polyelectrolyte and the counterion in a solution such that the polyelectrolyte self-assembles to form a plurality of polymer aggregates, the plurality of polymer aggregates having an average diameter less than about 100 nm, d) adding a precursor to the solution, wherein the precursor has a charge opposite the charge of the polyelectrolyte, and e) allowing the precursor to infuse each polymer aggregate and polymerize so as to produce composite nanoparticles. The composite nanoparticles comprise a polymer aggregate containing at least one polyelectrolyte and at least one counterion and a polymer network crosslinked throughout the polymer aggregate. The polymer network may be inorganic, e.g silicon-containing. | 09-02-2010 |
20130345099 | Nano-Encapsulated Triggered-Release Viscosity Breaker - A method for the encapsulation and triggered-release of water-soluble or water-dispersible materials. The method comprises a) providing an amount of electrolyte having a charge, b) providing an amount of counterion having a valence of at least 2, c) combining the polyelectrolyte and the counterion in a solution such that the polyelectrolyte self-assembles to form aggregates, d) adding a compound to be encapsulated, and e) adding nanoparticles to the solution such that nanoparticles arrange themselves around the aggregates. Release of the encapsulated species is triggered by disassembly or deformation of the microcapsules though disruption of the charge interactions. This method is specifically useful for the controlled viscosity reduction of the fracturing fluids commonly utilized in the oil field. | 12-26-2013 |
Vinit S. Murthy, Guilderland, NY US
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20100267594 | Nano-encapsulated triggered-release viscosity breakers - A method for the encapsulation and triggered-release of water-soluble or water-dispersible materials. The method comprises a) providing an amount of electrolyte having a charge, b) providing an amount of counterion having a valence of at least 2, c) combining the polyelectrolyte and the counterion in a solution such that the polyelectrolyte self-assembles to form aggregates, d) adding a compound to be encapsulated, and e) adding nanoparticles to the solution such that nanoparticles arrange themselves around the aggregates. Release of the encapsulated species is triggered by disassembly or deformation of the microcapsules though disruption of the charge interactions. This method is specifically useful for the controlled viscosity reduction of the fracturing fluids commonly utilized in the oil field. | 10-21-2010 |
Vinit Satish Murthy, West Chester, OH US
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20120217269 | Feeder for Particle Delivery - A feeder apparatus includes a hopper having a longitudinal axis and a wall having an external surface and an internal surface defining a thickness therebetween. The wall defines an infeed end for receipt of particulate material and an outfeed end for conveyance of the particulate material from the hopper. The outfeed end defines or has an outfeed aperture therein. A base disposed such that at least a portion of the base is substantially coextensive with the outfeed aperture. The base has at least one base aperture therethrough to facilitate conveyance of the particulate material from the hopper. The base aperture may be concentrically or eccentrically disposed relative to the longitudinal axis of said hopper. At least one of the base and the hopper is capable of rotation relative to another of the base and hopper, such that the base aperture is in at least intermittent in particulate flow communication with the outfeed aperture. | 08-30-2012 |
V.srinivasa Murthy, Winston-Salem, NC US
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20100081683 | NICOTINIC ACETYLCHOLINE RECEPTOR SUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES - Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are amide compounds which can be prepared from certain heteoraryl carboxylic acids and certain diazabicycloalkanes. The compounds exhibit selectivity for, and bind with high affinity to, neuronal nicotinic receptors of the a4β2 subtype in the central nervous system (CNS). The compounds and compositions can be used to treat and/or prevent a wide variety of conditions or disorders, particularly CNS disorders. The compounds can: (i) alter the number of nicotinic cholinergic receptors of the brain of the patient, (ii) exhibit neuroprotective effects, and (iii) when employed in effective amounts, not result in appreciable adverse side effects (e.g. side effects such as significant increases in blood pressure and heart rate, significant negative effects upon the gastrointestinal tract, and significant effects upon skeletal muscle). | 04-01-2010 |
V. Srinivasa Murthy, Winston-Salem, NC US
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20100144700 | HETEROCYCLIC-CARBONYL-DIAZABICYCLOALKANES AS MODULATORS OF THE NEURONAL NICOTINIC ACETYLCHOLINE ALPHA 4 BETA 2, SUBTYPE RECEPTOR FOR THE TREATMENT OF CNS RELATED DISORDERS - A compound of Formula 1: A-C(O)-Cy, wherein A is a diazabicyclic core, containing 7, 8, or 9 ring atoms, and selected from the following: 2,6-diazabicyclo[3.2.0]heptane; 3,6-diazabicyclo[3.ZO]heptane; 2,7-diazabicyclo[4.2.0]octane; 3,7-diazabicyclo[4.2.0]octane; 3,8-diazabicyclo[4.2.0]octane; 2,7-diazabicyclo[3.3.0]octane; 2,7-diazbicyclo[4.3.0]nonane; 2,8-diazbicyclo[4.3.0]nonane; 3,7-diazabicyclo[4.3.0]nonane; 3,8-diazabicyclo[4.3.0]nonane; 3,9-diazabicyclo[4.3.0]nonane; 2,6-diazabicyclo[3.2.1]octane; 3,6-diazabicyclo[3.2.1]octane; wherein the diazabicycle is attached as a radical to the depicted carbonyl via either one of the two ring nitrogen atoms, such that the carbonyl forms an amide bond with the ring nitrogen; Cy is a heteroaryl group; The compounds exhibit selectivity for, and bind with high affinity to, neuronal nicotinic receptors of the α402 subtype in the central nervous system (CNS). The compounds and compositions can be used to treat and/or prevent a wide variety of conditions or disorders, particularly CNS disorders. The compounds are believed to: (i) alter the number of nicotinic cholinergic receptors of the brain of the patient, (ii) exhibit neuroprotective effects, and (iii) when employed in effective amounts, not result in appreciable adverse side effects, namely side effects such as significant Increases in blood pressure and heart rate, significant negative effects upon the gastrointestinal tract, and significant effects upon skeletal muscle. | 06-10-2010 |
20100173932 | SUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES - Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are amide compounds which can be prepared from certain heteroaryl carboxylic acids and certain diazabicycloalkanes. The compounds exhibit selectivity for, and bind with high affinity to, neuronal nicotinic receptors of the α4β2 subtype in the central nervous system (CNS). The compounds and compositions can be used to treat and/or prevent a wide variety of conditions or disorders, particularly CNS disorders. The compounds can: (i) alter the number of nicotinic cholinergic receptors of the brain of the patient, (ii) exhibit neuroprotective effects, and (iii) when employed in effective amounts, not result in appreciable adverse side effects (e.g. side effects such as significant increases in blood pressure and heart rate, significant negative effects upon the gastrointestinal tract, and significant effects upon skeletal muscle). | 07-08-2010 |
20110071180 | SUB-TYPE SELECTIVE AMIDES OF DIAZABICYCLOALKANES - The present invention relates to compounds of the following formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 03-24-2011 |
Yerramilli V.s.n. Murthy, Falmouth, ME US
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20100240741 | PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS - Pharmaceutical compositions comprising an aptamer and an amino acid ester or amide or an aptamer; a divalent metal cation; and a carboxylic acid, a phospholipid, a phosphatidyl choline, or a sphingomyelin. Methods of treating or preventing a condition in an animal comprising administering to the animal the pharmaceutical compositions. | 09-23-2010 |
20110034430 | Phospholipid Gel Compositions for Drug Delivery and Methods of Treating Conditions Using Same - The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of a pharmaceutically active agent and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions. One particular type of condition for which the pharmaceutical compositions are useful is a microbial infection, e.g., of the skin, ear, or eye, especially for veterinary applications. | 02-10-2011 |